• 한국산업보건학회지
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• 제31권2호
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• pp.173-183
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• 2021

Objectives: This study evaluated the skin permeability of lawsone in henna hair dyes to understand the exposure characteristics of henna hair dyes in the human body. It examined the protective effects of protectants by applying protectants A, B, and C to test skin. Methods: Skin absorption tests were conducted using Franz diffusion cells according to OECD test guideline 428. After applying one kind of natural henna hair dye and chemical henna hair dye, respectively, to a standardized pig skin model, samples of receptor fluid were collected at 1h, 3h, 6h, and 24h. The skin permeation of lawsone was determined using HPLC. After the skin absorption experiment, the skin to which hair dye was applied was analyzed to determine the residual amount of lawsone in the skin. Results: The cumulative permeation of both natural and chemical henna hair dyes increased over time, and the natural henna hair dye had a flux value (t=3.194, p<.05) high both in the K_p value (t=3.207, p<.05) and the residual amount (t=22.701, p<.001). For skin treated with a protectant, the cumulative permeation of natural henna hair dye 24h control and the cumulative permeation of protectant A, B, and C increased over time. Flux and K_p values were in the order control > protectant A > protectant C > protectant B. The residual amount (F=4.469, p<.05) was in the order of protectant C > protectant A > protectant B > control. At 3h, the dye application time of natural henna hair dye, the lawsone flux value (F=4.454, p<.05) and K_p value (F=4.455, p<.05) were higher in the control group than in the protectant groups. The 24h cumulative permeation of the chemical henna hair dye increased with time in both the control and the protectant groups, and the flux and K_p values were in the order of protectant A > protectant C > protectant B > control. The residual amount (F=7.901, p<.01) was in the order of protectant B > protectant A> protectant C > control. Conclusions: Within the normal dyeing time for henna hair dye (three hours for natural henna hair dyes and 30 minutes for chemical henna hair dyes) lawsone skin penetration was not observed even when no protective agent was applied. After that time, however, evidence of skin penetration and retention of lawsone and the protective effect of protective agents were observed.

• 무역학회지
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• 제43권1호
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• pp.109-130
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• 2018

원산지결정기준 중 하나인 누적기준은 원산지결정기준을 완화 할 수 있는 방안으로 특정 조건들을 충족했을 때 비원산지재료도 원산지재료로 인정해주는 규정이다. 한-캐나다 FTA에서는 자동차 품목의 경우 기존의 일반적인 누적기준이 아닌 교차누적기준을 적용하였다. 이는 원산지결정기준의 확장과 편리함을 위한 것으로 제3국의 원재료나 중간재에도 원산지자격을 부여한다. 본 논문에서는 한-캐나다 FTA 발효 이전과 이후 교차누적의 대상 품목인 84, 85, 87, 94류의 대미자동차 부품 수입액의 변화의 여부를 실증분석하고 교차누적의 실효성을 살펴보았다. 분석대상은 각 류에서 자동차 부품으로 지정된 품목만 선택하여 분석하였는데 분석대상 품목 35개 품목 중 21개 품목에서 유의한 변화가 나타났다. 2015년 1월 기준으로 수입액이 단기적으로 큰 폭으로 증가하였거나, 추세적 증가율이 전보다 상승한 것으로 나타났다. 이러한 결과는 교차누적의 도입으로 우리나라 자동차 수출기업들이 한-캐나다 FTA의 교차누적을 활용하고 있음을 반증하는 것이라고 할 수 있다. 또한 수출확대와 시장확보를 위해 FTA 체결 시 교차누적의 도입을 적극적으로 검토할 필요성이 있다.

• Journal of Electrical Engineering and information Science
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• 제3권1호
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• pp.117-125
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• 1998

In this paper, in order to investigate the fading reduction effect of narrowband and broadband signals in an indoor multipath propagation environment, both the received narrowband signal while a vehicle unit in motion and the frequency sweeped broadband signal received by vertical polarized antenna, horizontal polarized antenna and circularly polarized antenna are analyzed. Specifically, in order to evaluate polarization diversity effect, we examined the difference of fading reduction effect between the polarization diversity reception and the space diversity reception. Using the correlation coefficient and correlation graph for the polarization diversity branches, the diversity effect is evaluated. And also, using the cumulative distribution for the received signal strength simulated by diversity reception, the diversity effect is also estimated. From the evaluation results it was found that the polarization diversity which use a circularly polarized antenna at the transmitting end and the vertical and horizontal polarized antenna branches at the receiving end is markedly excellent.

• 경영과정보연구
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• 제4권
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• pp.327-348
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• 2000

There are three major motives for M&A, financial synergy effect, operating & managerial synergy effect, and tax effect. The purpose of this study is to prove the operating & managerial synergy effect of M&A. To do this, we analyze the market-ripple effect of M&A, focusing on the increase in market power. Specifically we use cross-sectional data from 1985 to 1998 to show whether a market power of mergers is higher than that of a matched non-merging control group. we use time series data to show whether a market power of merger is higher than that of pre-merger. Also we use the event study using market model to show the stock price movement after mergers. The result is that although revenue increase after mergers, profit of the firms does not improve after mergers. Also there is sufficient evidence to say that there is a cumulative abnormal return for the firms after mergers.

• 한국조리학회지
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• 제22권4호
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• pp.181-191
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• 2016

본 연구에서는 친환경농산물 선택결정요인이 소비자신뢰와 추천의도에 미치는 영향요인들과 그 요인을 이용한 앞으로의 활용방안을 제시하고자 한다. 총 220부의 설문지를 배포하여 불성실하게 응답한 10부의 설문지를 제외한 나머지 210부의 유효한 설문지를 실증연구에 사용되었다. 조사연구의 목적을 달성하기 위하여 통계프로그램 SPSS 18.0을 활용하여 빈도분석, 요인분석 및 신뢰도분석, 상관관계분석, 회귀분석을 실시하였다. 분석결과를 보면 선택결정요인에 대한 측정항목의 탐색적 요인분석 결과, 3개 요인으로 KMO 값은 0.735, 총분산비율 79.373%, 소비자신뢰에 대한 요인분석은 총분산비율 75.431%, KMO 값은 0.695로 나타났다. 추천의도에 대한 요인분석은 총분산설명력 68.428%, KMO 값은 0.694로 나타났다. 변수들 간의 상관관계가 다른 변수에 의해 설명되는 정도가 좋게 분석되었고, 유의확률이 0.000으로 나타나 전반적으로 변수들 간의 상관관계는 유의적이다. 따라서 선택결정요인에 따른 소비자신뢰는 추천의도에 미치는 영향에 관한 가설은 채택되었다.

• Journal of Advanced Research in Ocean Engineering
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• 제1권2호
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• pp.106-114
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• 2015

In the fabrication of offshore oil and gas facilities, the significance of dimension control is growing continuously. But, it is difficult to determine the deformation of the structure during fabrication by simple lab tests due to the large size and the complicated shape. Strain-boundary method (a kind of shrinkage method) based on the shell element was proposed to predict the welding distortion of a structure effectively. Modeling of weld geometry in shell element is still a difficult task. In this paper, a concept of imaginary temperature pair is introduced to handle the effect of geometric factors such as groove shape, plate thickness and pass number, etc. Single pass imaginary temperature pair formula is derived from the relation between the groove area and the FE mesh size. By considering the contribution of each weld layer to the whole weldment, multi-pass imaginary temperature is also derived. Since the temperature difference represents the distortion increment, cumulative distortion curve can be drawn by integrating the temperature difference. This curve will be a useful solution when engineers meet some problems occurred in the shipyard. A typical example is shown about utilization of this curve. Several verifications are conducted to examine the validity of the proposed methodology. The applicability of the model is also demonstrated by applying it to the fabrication process of the heavy ship block. It is expected that the imaginary temperature model can effectively solve the modeling problem in shell element. It is also expected that the cumulative distortion curve derived from the imaginary temperature can offer useful qualitative information about angular distortion without FE analysis.

• 한국실내디자인학회논문집
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• 제27권3호
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• pp.136-144
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• 2018

The purpose of this study is to examined the unconscious response of the pupil in the observation toward the image in the eye-tracking experiments that target on a large complex cultural space. Twenty-five men participated in this experiment and the observation data were analyzed in seconds per minute on watching time. It could examine the unconscious response of information searching in the change of pupil size in the process of observing the space. The results could be defined as following several points. First, it was possible to outline the unconscious response characteristics of pupil by analyzing sudden changes in pupil size as total, cumulative, and individual. The response characteristics using frequency and time can be utilized as the analytical method to examine the degree of interest of spatial components according to the purpose of analysis in the future. Second, according to the over ${\pm}5%$ of cumulative variation rate on the pupil size change, during in the 60 seconds, the continuous pupil dilation was used 25.2 seconds in 8.8 rounds and the pupil reduction was used 18.0 seconds in 7.0 rounds. Third, when the variation rate of ${\pm}5%$ or more was regarded as the sudden changes on pupil size by individual variation, the pupil dilation was 7.2 rounds of 8.6 seconds and pupil reduction was 6.0 seconds in 5.0 rounds. This means that the pupil increases 9.3% in one expansion and decreases -8.5% in the reduction process. As regarding pupil changes as cumulative rate, it appeared high change rate on pupil reduction but it became higher on pupil dilation in individual.

• Journal of Preventive Medicine and Public Health
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• 제28권2호
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• pp.386-397
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• 1995

A cross sectional study was performed to evaluate the neurobehavioral effects of chronic exposure of complex organic solvents, using NCTB(Neurobehavioral Core Test Battery) recommended by WHO(World Health Organization). Forty female shoe factory workers and twenty-two controls matched with age were participated. The tests were performed in the morning before start of work, to exclude the effects of acute exposure. Workers were exposed mainly to toluene, methyl ethyl ketone, n-hexane, cyclo-hexane, dichloroethylene, trichloroethylene, benzene, xylenes etc. The ranges of present solvent exposure of hygienic effect were $0.46\sim0.71$ in the process using adhesives indirectly, and $1.83\sim2.39$ in the process using it directly. We reclassified the subjects, according to cumulative exposure. It showed significantly poorer performances in high exposed group on Santa Ana Dexterity and Benton Visual Retention, compared with control group. After controlling confounder, the significances were still remained. But, further cohort studies, having the information of personal exposure dose from entering a factory, are required to clarify the effects of chronic exposure of complex organic solvents in relation to dose and duration of exposure.

• Childhood Kidney Diseases
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• 제20권2호
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• pp.45-49
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• 2016

Purpose: This study was performed to evaluate the effects of cyclosporine-A (CsA) on linear growth in pediatric patients with steroid-dependent (SDNS) or resistant nephrotic syndrome (SRNS). Methods: Thirty-five pediatric patients with SDNS or SRNS undergoing glucocorticoid (GC) and/or CsA treatment were retrospectively reviewed. Seventeen patients were treated with GC alone and 18 were treated with GC and CsA. The cumulative doses of GC and CsA were quantified (mg/kg/day). Linear growth during the follow-up period was defined as the difference in Z-score between the initial and final height according to the follow-up period (${\Delta}$ height Z score/year). The associations between linear growth and clinical parameters were analyzed. Results: The linear growth of patients in the two groups was not significantly different (P=0.262). The ${\Delta}$ height Z score/year did not show a significant correlation with the cumulative doses of CsA, but was negatively correlated with the cumulative dose of GC and positively correlated with the Z score for height at the time of diagnosis. Conclusion: In children with SDNS or SRNS undergoing GC therapy, added CsA treatment may not have harmful effects on linear growth.

• Asian-Australasian Journal of Animal Sciences
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• 제19권5호
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• pp.627-631
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• 2006

The objective of this study was to evaluate the association of genetic differences in the bovine leptin gene and milk yield, reproduction, body condition score (BCS), and plasma glucose level in Iranian Holstein cows. In total, two hundred and thirty eight cows were used and genotyped for a restricted fragment length polymorphism at the leptin gene locus. Two genotypes, AA and AB, have been distinguished which have the frequencies of 0.89 and 0.11, respectively. The genotypes were distributed according to the Hardy - Weinberg equilibrium ($x^2$ = 0.733). During the first 12 wk of lactation, milk yield and composition, live weight, BCS and plasma glucose were measured in 50 cows. Data were analyzed based on a repeated measures ANOVA. During this period, milk yield and composition, live weight, BCS and plasma glucose level were similar among the genotypes. The first cumulative 60-d milk yield, 305-d milk yield, days to first breeding, days open and days from first breeding to conception using previous lactation records were also analyzed using Standard Least Square within mixed models. Fixed effects were year, season, parity and age at calving, and sire. For the reproductive traits the cumulative first 60-d milk yield was also added to the model. Animal was fitted as a random effect. A significant association was detected between the RFLP-AB genotype and 305-d milk yield (p<0.05). The first 60-d cumulative milk yield was similar for the two genotypes (p = 0.21) and tended to be higher in the heterozygous cows. The heterozygous genotypes at the above mentioned locus had a trend to better reproductive performance than the homozygous. The results demonstrate that the RFLP B-allele can yield a higher 305-d milk production with a trend to better reproductive performance.