Objectives: This study was conducted to estimate the health-related quality of life using EQ5-D by socio-demographic characteristics and mental health among Seoul citizens for developing health promotion programs. Methods: The study subjects using cluster-stratified sampling method were 1234 adults over 19 years old from 17 dong, S-Ku in Seoul City. A cross-sectional study with face-to-face interview was used to collect data. A questionnaire measuring socio-demographic variables, Symptom Checklist-90-Revised (SCL-90-R) and Euroqol EQ-5D instrument. The Difference on the EQ-5D index among groups were tested with Mann-Whitney U test and Kruskal Wallis test. Results: The mean EQ-5D index for all subjects was 0.946(${\pm}0.105$). The EQ-5D index were significantly different by sex, age, marital status, eduction level and income. The EQ5-D indexes among clinical mental health groups were the lowest scores and significantly different from other groups. Conclusion: The findings suggest that the future intervention of health promotion programs should be carefully designed and tailored by socio-demographic variables. Especially, the mental health programs need to be developed.
In this paper, the displacement and stress strength safeties have been presented for cylindrical hollow rollers of a wire saw machine. Using the finite element method, the hollow roller with Y-shaped shift and vertical columns between three tubes has been developed to analyze the displacement behavior and stress strength safeties. For the same diameter and length of hollow roller models with a different weight, the displacement behavior safety of Y-shaped shift column and vertical column models is heavily depending on the total length of a hollow roller, which is closely related to the bending moment of a hollow roller structure. But, the stress strength of a hollow roller is more influenced by the cross sectional area of a hollow roller for the similar weight. Thus, this paper recommends Y-shaped hollow roller for increasing the roller strength safety and decreasing a total roller weight.
Purpose: The purpose of this study was to investigate the relationships between LLFDI and quality of sleep in older men with prostatic hypertrophic symptoms. Methods: The secondary analysis of data collected for the 2nd stage BK(Brain Korea)21 project was performed. The original data were collected using a cross-sectional, face-to-face, and private interview method. The questionnaires consisted of prostatic hypertrophic symptoms, late-life function and disability, quality of sleep, and demographic profiles. Results: A total of 112 older men included in this study. The major findings of this study were as follow; 1) 29.5% of participants had more than moderate symptoms of prostatic hypertrophy. 2) There were a significant positive correlation of prostatic hypertrophic symptoms with subjective sleep quality, sleep latency, sleep disturbances, use of sleeping medication, and daytime dysfunction found, whereas there was a negative relationship with frequency dimension. 3) The LLFDI is significantly associated with urgency, weak stream, and intermittency. The quality of sleep is significantly associated with weak stream which explained 11.2% of variance. Conclusion: These results may contribute to a better understanding late-life function and disability, quality of sleep in older men with prostatic hypertrophic symptoms. Therefore, health programs for prompting older men's health should be planned based on results of the study.
Omran, Dalia Abd El Hamid;Awad, AbuBakr Hussein;Mabrouk, Mahasen Abd El Rahman;Soliman, Ahmad Fouad;Aziz, Ashraf Omar Abdel
Asian Pacific Journal of Cancer Prevention
/
v.16
no.1
/
pp.381-385
/
2015
Background:Hepatocellular carcinoma (HCC) is the second most common malignancy in Egypt. Data mining is a method of predictive analysis which can explore tremendous volumes of information to discover hidden patterns and relationships. Our aim here was to develop a non-invasive algorithm for prediction of HCC. Such an algorithm should be economical, reliable, easy to apply and acceptable by domain experts. Methods: This cross-sectional study enrolled 315 patients with hepatitis C virus (HCV) related chronic liver disease (CLD); 135 HCC, 116 cirrhotic patients without HCC and 64 patients with chronic hepatitis C. Using data mining analysis, we constructed a decision tree learning algorithm to predict HCC. Results: The decision tree algorithm was able to predict HCC with recall (sensitivity) of 83.5% and precession (specificity) of 83.3% using only routine data. The correctly classified instances were 259 (82.2%), and the incorrectly classified instances were 56 (17.8%). Out of 29 attributes, serum alpha fetoprotein (AFP), with an optimal cutoff value of ${\geq}50.3ng/ml$ was selected as the best predictor of HCC. To a lesser extent, male sex, presence of cirrhosis, AST>64U/L, and ascites were variables associated with HCC. Conclusion: Data mining analysis allows discovery of hidden patterns and enables the development of models to predict HCC, utilizing routine data as an alternative to CT and liver biopsy. This study has highlighted a new cutoff for AFP (${\geq}50.3ng/ml$). Presence of a score of >2 risk variables (out of 5) can successfully predict HCC with a sensitivity of 96% and specificity of 82%.
Background: Prostatic adenocarcinoma is one of the main causes of cancer death, and its timely diagnosis and preventing its progression dramatically helps improve life indexes. Given the high disease recurrence rate, today, research is more inclined toward exploring causes of recurrence and development, and innovation of modern treatment methods. Several studies have explored over-expression of human epidermal growth factor receptor 2 (HER-2/neu) in prostatic cancer so far, with different results. Thus, it was decided to investigate HER-2/neu overexpression in patients with prostatic adenocarcinoma in Iran. Materials and Methods: A sample size of 40 patients with prostate cancer entered the study, using a cross-sectional, non-randomized sampling method. Parameters studied included patient age at surgery, Gleason score, serum prostatic specific antigen (PSA) before surgery, and positive sample rate after immunohistochemical staining to investigate HER-2/neu overexpression. Results: In terms of HER-2/neu receptor staining rate, of 40 slides, 16 (40%) scored 0, 13 (32.5%) 1+, 7 (17.5%) 2+, and 4 (10%) 3+. In total 27.5% of slides showed HER-2/neu overexpression. In terms of age, an inverse correlation was found (-0.181), but without significance (p=0.263). In terms of serum PSA, the correlation coefficient was 0.449 (p=0.004). With respect to Gleason score, the coefficient was 0.190 (p=0.240). Conclusions: In this study, HER-2/neu overexpression occurred in 27.5% of prostate cancer cases, which is a relatively high figure, compared to similar studies elsewhere. While, we failed to reveal any relationship between HER-2/neu expression status with progression and prognosis of disease, it was demonstrated that the serum PSA level was significantly higher in cases with increased receptor expression.
We investigated the distribution of HPV genotypes in Uyghur women in Xinjiang region of China, and behavioral factors which could predispose them to HPV infection. In this cross-sectional study, women aged 15-59 years were recruited by cluster sampling method in Yutian region in 2009. Liquid-based cytology samples were analyzed centrally for HPV genotype with a linear array detector. Univariate and multivariate logistic regression analyses were performed to identify behavioral risk factors for HPV infection. A total of 883 Uyghur women were recruited successfully. The prevalence of high-risk HPV and low-risk HPV were 7.25% and 1.58%, respectively; the most common HPVs were HPV16, 51, 31, 39 and 58. We found that age of first sexual intercourse was a strong predictor for HPV infection (odds ratio of 4.01 for ${\leq}15$ years versus ${\geq}25$). Having sexual partners ${\geq}3$ was the second predictor (OR 3.69, 95% CI 2.24-7.16). Cleaning the vagina after sex showed an increased risk of HPV infection (OR 2.72; 95% CI 1.98-5.13); Using the condom showed protective factors for HPV infection (OR 0.36; 95%CI0.12-0.53). HPV16, 51, 31, 39 and 58 were the priority types; the age of first sexual intercourse was identified as a major risk factor for HPV infection. Other notable risks were number of sexual partners and cleaning the vagina after sex. Changing these behavioral risk factors could help to reduce the occurrence of cervical cancer in this population.
Breast and cervical cancers are among leading causes of morbidity and mortality in women worldwide. Regular screening is very important for early detection of these cancers, but studies indicate low rates of screening participation. In this survey we studied the rate of screening participation among women 18-64 years old referred to urban health centers in Kerman, Iran in 2015. A cross-sectional study was carried out on 240 women who were selected using a multistage sampling method. Data collected using a questionnaire covered demographics and questions about common cancer screening status in women. Analysis was by SPSS 19. The mean age of participants was $31.7{\pm}7$. Most (97.1%) were married, housewives (83.3%), had high school diploma (43.8%) and a monthly income more than ten million Rls. The frequency of the Pap test performance was higher in women who were employed and with a university degree (p<0.05). The frequency of mammography performance in women over 40 years was also higher in women with university degree (p<0.05). There was no statistically significant difference in the frequency of pelvic examination, and self and clinical breast examinations based on education, household income and employment (p>0.05). Our study found that the rate of screening participation among women is low. Investigation of the barriers, increasing the awareness of women about the importance and advantages of screening and also more incentives for health personnel especially family physicians to pay more attention to preventive programs could be effective.
A plate type supporting structure of a tube bundle in axial flow generates a certain band of a high frequency periodic excitation of a vortex shedding and/or a flow separation due to sharp edge of the plate thickness and a severe pressure drop due to a cross-sectional area of the supports. With a design consideration of the low vibration and a small flow resistance, the analysis method is uniquely confined to an experimental approach because a complex geometry of a cylindrical tube bundle and/or physical phenomena related to the fluid-structure interaction of tube bundle in a flow impede a theoretical or a numerical approach. A 5x5 cylindrical tube bundle with 5 supports which were discretely located along the bundle's axis was tested in the FIVPET hydraulic test loop for a design evaluation and an analysis perspectives. A high frequency flow-induced vibration of the supporting structures of the cylindrical tube bundle was measured at a outer surface of a supporting structure through a transparent flow housing by the laser dopper vibrometer. Pressure drop in-between three measurement distances was measured by the differential pressure transmitter. High frequency vibration and pressure drop fairly depends on the geometric design of supporting structure. So, these two parameters would be used as a qualitative design variables for design evaluation and analysis.
Purpose: The purpose of this study was investigate the relationships among perceived social support, instrumental support needs, and depression of healthy, community dwelling elderly women. Method: This study was designed to examine whether the perceived social support and instrumental support were correlated with depression in elderly women. Data were cross-sectional and community-dwelling elderly individuals. The subject was 98 elderly women recruited from Elderly Welfare Center and Community center for Elderly. The instruments for this study were Personal Resource Questionnaire-part II, Geriatric Depression Scale (Short Form), and Instrumental Support Activities Checklist. Data were gathered by means of structured personal interviews. The internal consistency of the instruments was relatively good. Result: The participants' perceived social support was moderately high and instrumental support needs was low. Depression was mild and moderate relatively. The correlation analysis showed that the perceived social support was negatively related to depression and negatively related with instrumental support needs. Conclusion: The findings suggested that more perceived social support, less their depressive symptom in elderly women. It also revealed that the age, marital status, and socioeconomic status of elderly women also are important indicator of the elderly depression. Therefore nursing assessment and the design of intervention that incorporate the determinants supported in this study, such as perceived social support of the elderly women are needed in adopting and maintain health promoting lifestyle for the mental health and effective functioning in later life in women.
Background: The Asia Pacific consensus for colorectal cancer (CRC) recommends that screening programs should begin by the age of 50. However, there have been reports about increasing incidence of CRC at a younger age (i.e. early-onset CRC). Little is known about the features of early-onset CRC in the Vietnamese population. Aim: To describe the clinical, endoscopic and pathological characteristics of early-onset CRC in Vietnamese. Method: A prospective, cross-sectional study was conducted at the University Medical Center from March 2009 to March 2011. All patients with definite pathological diagnosis of CRC were recruited. The early-onset CRC group were analyzed in comparison with the late-onset (i.e. ${\geq}$ 50-year-old) CRC group. Results: The rate of early-onset CRC was 28% (112/400) with a male-to-female ratio of 1.3. Some 22.3% (25/112) of the patients only experienced abdominal pain and/or change in bowel habit without alarming symptoms, 42.9% (48/112) considering their symptoms intermittent. The rate of familial history of CRC in early-onset group was significantly higher that of the late-onset group (21.4% versus 7.6%, p<0.001). The distribution of CRC lesions in rectum, distal and proximal colon were 51.8% (58/112), 26.8% (30/112) and 21.4% (24/112), respectively; which was not different from that in the late-onset group (${\chi}2$, p = 0.29). The rates for poorly differentiated tumors were also not significantly different between the two groups: 12.4% (14/112) versus 8.3% (24/288) (${\chi}2$, p = 0.25). Conclusion: A high proportion of CRC in Viet Nam appear at an earlier age than that recommended for screening by the Asia Pacific consensus. Family history was a risk factor of early-onset CRC. Diagnosis of early-onset CRC needs more attention because of the lack of alarming symptoms and their intermittent patterns as described by the patients.
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