• Title/Summary/Keyword: cross sectional method

Search Result 1,324, Processing Time 0.026 seconds

Comparison study of modeling covariance matrix for multivariate longitudinal data (다변량 경시적 자료 분석을 위한 공분산 행렬의 모형화 비교 연구)

  • Kwak, Na Young;Lee, Keunbaik
    • The Korean Journal of Applied Statistics
    • /
    • v.33 no.3
    • /
    • pp.281-296
    • /
    • 2020
  • Repeated outcomes from the same subjects are referred to as longitudinal data. Analysis of the data requires different methods unlike cross-sectional data analysis. It is important to model the covariance matrix because the correlation between the repeated outcomes must be considered when estimating the effects of covariates on the mean response. However, the modeling of the covariance matrix is tricky because there are many parameters to be estimated, and the estimated covariance matrix should be positive definite. In this paper, we consider analysis of multivariate longitudinal data via two modeling methodologies for the covariance matrix for multivariate longitudinal data. Both methods describe serial correlations of multivariate longitudinal outcomes using a modified Cholesky decomposition. However, the two methods consider different decompositions to explain the correlation between simultaneous responses. The first method uses enhanced linear covariance models so that the covariance matrix satisfies a positive definiteness condition; in addition, and principal component analysis and maximization-minimization algorithm (MM algorithm) were used to estimate model parameters. The second method considers variance-correlation decomposition and hypersphere decomposition to model covariance matrix. Simulations are used to compare the performance of the two methodologies.

Modeling of Hemodynamics in Stenosed Artery (협착 동맥혈관의 혈류유동 모델링)

  • Kim, Seong-Jong;Park, Young-Ran;Kim, Shagn-Jin;Kang, Hyung-Sub;Kim, Jin-Shang;Oh, Sung-Hoon;Kang, Sung-Jun;Kim, Gi-Beum
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.13 no.5
    • /
    • pp.2285-2290
    • /
    • 2012
  • This study is about atherosclerosis which occupies the highest rate in many diseases people have and we have studied about atherosclerosis for abdominal aorta. Atherosclerosis is the phenomenon which blood vessel gets narrower, harder and thicker due to the stenosis of colesterol in blood vessel. If it becomes worse, arteries will be hard and blood can't flow smoothly, and even it can reach to death. In this study, the geometric models of the considered stenotic blood flow are two different types of constriction of cross-sectional area of blood vessel; 20 and 45% of constriction in each elastic wall and rigid wall. We have modeled by using finite element method to observe the changes of velocity and pressure. In case of the diameter of blood vessel decreased 45% in elastic wall model, the values of velocity and pressure were higher than the case of 20% and in case of the diameter of blood vessel decreased 45% in rigid wall model, the values of velocity and pressure were higher than the case of 20%. In cases of elastic wall models of the diameters of blood vessels decreased each of 20% and 45%, recirculation zones appeared. This results show understanding of hemodynamic properties depending on stenosed blood vessels.

THE RISK INDICATORS OF DENTAL EROSION IN 8- AND 9-YEAR-OLD SCHOOLCHILDREN IN YANGSAN (양산시에 거주하는 8~9세 어린이의 치아침식증과 관련된 위험요인 분석)

  • Kim, Hyun-Jung;Kim, Shin;Jeong, Tae-Sung
    • Journal of the korean academy of Pediatric Dentistry
    • /
    • v.40 no.1
    • /
    • pp.1-10
    • /
    • 2013
  • Dental erosion is a complex disease of multifactorial etiology with high risk of loss of tooth structure, which still has not been appropriate interest. The aim of this study was to assess the prevalence and risk indicators of dental erosion in Korean school children. A cross-sectional survey was performed on 664 children aged 8~9 years. Data concerning gender, types of caregiver, dietary habits, oral hygiene habits and parental knowledge were obtained from a questionnaire, which was answered by the parents of the children. Association between erosion and the factors were statistically analyzed with chi-squared test and independent t-test at a significance level of 0.05. Dental erosion was present in 242 children. In carbonated drinks, dental erosion was significantly associated with preference, frequency of consumption and the ingestion method (p < 0.05). In fruit juices, dental erosion was significantly associated with preference and frequency of consumption (p < 0.05), but no significant associations were found with the ingestion method (p > 0.05). There were no significant associations between dental erosion and gender, type of caregiver, oral hygiene habits and parental knowledge (p > 0.05). In conclusion, it was considered that motivation to be followed by practice is important as well as education for prevention of dental erosion.

A simple colorimetric method for the clinical evaluation of caries activity in adults (성인의 치면세균막 내 산생성능력과 치아우식경험과의 연관성)

  • Kim, Hyo-Jung;Ku, Hye-Min;Lee, Eun-Song;Kwon, Ho-Keun;Kim, Baek-Il
    • The Journal of the Korean dental association
    • /
    • v.55 no.6
    • /
    • pp.413-422
    • /
    • 2017
  • Purpose: The aim of this study was to confirm the validity of the $Cariview^{TM}$, test in adults by assessing correlations between $Cariview^{TM}$, scores and caries experience using a quantitative light-induced fluorescence (QLF) technique. Methods: This retrospective cross-sectional study included 111 patients aged 19-64 years who visited a dental clinic in Seoul from 2015 to 2016, and underwent the $Cariview^{TM}$, test and had their teeth photographed with the Qraycam. Plaque was scraped with sterilized cotton swabs, and then placed in a culture medium and incubated at $37^{\circ}C$ for 48 h. Finally, the degree of color change was evaluated, and scored on a 0-100 point scale. Caries experience index included not only cavitated lesions but also early caries that were detected on white and fluorescence images. Participants were divided into low, moderate and high caries risk groups according to the $Cariview^{TM}$, score, and caries experience was compared between risk groups using ANCOVA. Spearman correlation coefficients were calculated to analyze the associations between $Cariview^{TM}$, scores and caries indices. Result: The mean age of the participants was 40 years, and the mean $Cariview^{TM}$, score was $53.6{\pm}20.7$. The WDMFT and the DMFT indices significantly increased with caries risk, and this increase was significantly different between the low- and high-risk groups. The $Cariview^{TM}$, test scores were significantly correlated with the WDMFT (r = 0.28, P = 0.003) and DMFT (r = 0.29, P = 0.002) indices. Conclusion: The $Cariview^{TM}$, test could be a clinically useful and simple method for assessing caries risk in adults.

  • PDF

Fabrication and loss measurement of $P_2O_5-SiO_2$ optical waveguides on Si (Si을 기판으로한 $P_2O_5-SiO_2$ 광도파로의 제작 및 손실측정)

  • 이형종;임기건;정창섭;정환재;김진승
    • Korean Journal of Optics and Photonics
    • /
    • v.3 no.4
    • /
    • pp.258-265
    • /
    • 1992
  • A low loss optical waveguide of $P_{2}O_{5}-SiO_{2}$on Si substrate is produced by using the chemical vapour deposition method of $SiO_2$ thin films used in Si technology. Propagation loss of the waveguide layer was 1.65 dB/cm as produced and reduced down to 0.1 dB/cm after heat treatment at $1100^{\circ}C$. By using laser lithography and reactive ion etching method $P_{2}O_{5}-SiO_{2}$ waveguide was produced and subsequently annealed at $1100^{\circ}C$.As a result of this annealing the shape of the waveguide core was changed from rectangular to semi-circular form, and the propagation loss was reduced as down to 0.03 dB/cm at 0.6328$\mu$m and 0.04dB/cm at 1.53$\mu$m. We think that the mechanism of the reduction in propagation loss during the heat treatment is the following: 1) The hydrogen bonding in waveguide layer, which causes absorption loss, is dissociated and diffused out. 2) The roughness of the interface and the micro-structure of the waveguide layer is removed. 3) The irregularities in the cross-sectional shape of the waveguide which was induced during the lithographic process were disappeared by flowing of the waveguide core.

  • PDF

The Analysis of Research Trends of Elderly in the Dental Hygiene Discipline (치위생학에서의 노인연구동향)

  • Goong, Hwa-Soo;Seo, Kawoun
    • Journal of dental hygiene science
    • /
    • v.18 no.4
    • /
    • pp.201-209
    • /
    • 2018
  • The aim of this study was to identify bibliographic characteristics and research trends of articles published on the elderly people in dental hygiene. An analysis was done of 191 articles published from 1999 to 2017. Bibliographic characteristics were nine items such as publication journal, research design, research participants, number of researchers, data analysis method, keywords, research topic, and validity and reliability report. The collected data were analyzed using descriptive statistics of statistical program. First, the research on the elderly, which was published in dental hygiene, started to be published in 1999 and on going. Though major publications have been published in Journal of Korean Society of Dental Hygiene and Journal of Dental Hygiene Science, the kinds of journals are becoming diverse. Second, cross-sectional research was the most. Third, the elderly were the most studied subjects, but the criteria varied. Fourth, the number of authors was largest in order of two and three person. Fifth, data analysis method was in order of descriptive statistics, t-test, and ANOVA. Sixth, there were many duplication of keywords about oral, elderly, and health. Seventh, oral health behavior science was the most studied subject. Eighth, validity and reliability were reported at 27.4% and 51.6%, respectively. Ninth, only 15.7% of study was founded research funding. Based on the results of this study, we consider increase experimental research further. Therefore, it is recommeded that validity and reliability should be reported in research paper, and the keywords used in the field of dental hygiene should be agreed upon.

Market Imperfections as an Explanation for Higher Premiums in Foreign Takeovers of U.S. Companies (외국기업(外國企業)이 미국기업(美國企業)을 인수(引受)할 때 지불(支拂)하는 높은 프레미엄에 대한 설명(說明)으로서의 시장불완전성(市場不完全性))

  • Jung, Hyung-Chan
    • The Korean Journal of Financial Management
    • /
    • v.8 no.2
    • /
    • pp.209-255
    • /
    • 1991
  • This paper develops a simple model to explain the reasons why foreign acquirers pay significantly higher premiums for U.S. target firms than do U.S. buyers. We also provide empirical work on the valuation effect of foreign takeovers and the determinants of the wealth gains of U.S. target shareholders involved in foreign takeovers. The results indicate that target wealth gains are significantly higher in foreign takeovers than in domestic takeovers, after controlling for the wealth effects of payment method, acquisition type, tax status, size and time period of bids. This confirms the valuation effect of foreign takeovers. Furthermore, the results of cross-sectional regression analysis show that the variation in U.S. target wealth gains is explained by extra tax benefits stemming from double tax deductions for acquisition-related interest expenses incurred by foreign acquirers. These findings imply that differential taxation across tax jurisdictions is the main source of the valuation effect of foreign takeovers. In addition, we find that there exists a valuation effect of the nationality of the foreign acquirers. Japanese companies pay significantly higher premiums than do non-Japanese acquirers. The finding also indicates that competition among bidders increases the abnormal returns to U.S. target shareholders in foreign takeovers.

  • PDF

Measurement of Flexural Modulus of Lamination Layers on Flexible Substrates (유연 기판 위 적층 필름의 굽힘 탄성계수 측정)

  • Lee, Tae-Ik;Kim, Cheolgyu;Kim, Min Sung;Kim, Taek-Soo
    • Journal of the Microelectronics and Packaging Society
    • /
    • v.23 no.3
    • /
    • pp.63-67
    • /
    • 2016
  • In this paper, we present an indirect method of elastic modulus measurement for various lamination layers formed on polymer-based compliant substrates. Although the elastic modulus of every component is crucial for mechanically reliable microelectronic devices, it is difficult to accurately measure the film properties because the lamination layers are hardly detached from the substrate. In order to resolve the problem, 3-point bending test is conducted with a film-substrate specimen and area transformation rule is applied to the cross-sectional area of the film region. With known substrate modulus, a modulus ratio between the film and the substrate is calculated using bending stiffness of the multilayered specimen obtained from the 3-point bending test. This method is verified using electroplated copper specimens with two types of film-substrate structure; double-sided film and single sided film. Also, common dielectric layers, prepreg (PPG) and dry film solder resist (DF SR), are measured with the double-sided specimen type. The results of copper (110.3 GPa), PPG (22.3 GPa), DF SR (5.0 GPa) were measured with high precision.

A Biomechanical Modeling of Human Pharyngeal Muscular Dysfunction by Using FEM(Finite Element Method) (유한요소법을 이용한 인두의 기능이상에 대한 생체역학적 모델)

  • Kim Sung Jae;Bae Ha Suk;Choi Byeong Cheol;Kim Sung Min
    • Journal of Biomedical Engineering Research
    • /
    • v.24 no.6 s.81
    • /
    • pp.515-522
    • /
    • 2003
  • Pharynx is a system transporting foods by peristaltic motion(contraction and expansion movement! into the esophagus and functioning as airway passages. In this study, structural changes of pharyngeal dysfunction are analyzed by biomechanical model using CT and FEM(finite clement method). Loading condition was assumed that equal pressure was loaded sequentially to inside of pharyngeal tissue. In order to analyze the pharyngeal muscular dysfunction by biomechanical model. the pharyngeal dysfunctions was classified into 3 cases. Taking into account the clinical complication by neuromuscular symptoms such as pharyngeal dysfunction after stroke. we assumed that a change of material property is caused by muscular tissue stiffness. A deformation of cross sectional area of the pharynx is analyzed increasing the stiffness $25\%,\;50\%,\;75\%$ in each case on the basis of stress-strain relationship. Based on three-dimensional reconstruction of pharyngeal structure using limited factor - techniques and the optimization procedure by means of inverse dynamic approach. the biomechanical model of the human pharynx is implemented. The results may be used as clinical index illustrating the degree of pharyngeal muscular dysfunction. This study may be used as useful diagnostic model in discovering early deglutitory impediment caused by physiological or pathological pharyngeal dysfunction.

Pillar stability in very near-twin tunnels (초근접 병설터널의 필라 안정성 확보)

  • Kim, Donggyou;Koh, Sungyil;Lee, Jeongyong;Lee, Chulhee
    • Journal of Korean Tunnelling and Underground Space Association
    • /
    • v.24 no.6
    • /
    • pp.699-714
    • /
    • 2022
  • The objective of this study is to suggest a safe and economical pillar reinforcement method when very near-twin tunnels with a minimum interval of 1 m passes through a soft zone such as weathered soil or weathered rock. A standard cross-sectional view of a two-lane road tunnel was applied to suggest a pillar reinforcement method for the very near-twin tunnels. The thickness of the pillar was 1 m. The ground condition around the tunnel was weathered soil or weathered rock. There were four reinforcement methods for pillar stability evaluation. These were rock bolt reinforcement, pre-stressed steel strand reinforcement, horizontal steel pipe grouting reinforcement, horizontal steel pipe grouting + prestressed steel strand reinforcement. When the ground condition was weathered soil, only the pillar reinforced the horizontal steel pipe grouting + prestressed steel strand did not failed. When the ground condition was weathered rock, there were no failure of the pillar reinforced the horizontal steel pipe grouting or the horizontal steel pipe grouting + prestressed steel strand. It is considered that the horizontal steel pipe grouting reinforcement played a role in increasing the stability of the upper part of the pillar by supporting the upper load applied to the upper part of the pillar.