• 제목/요약/키워드: cross links

검색결과 148건 처리시간 0.022초

링크확률과 개체명 인식을 이용한 영-한 교차언어 링크 탐색 (English-Korean Cross-lingual Link Discovery Using Link Probability and Named Entity Recognition)

  • 강신재
    • 한국지능시스템학회논문지
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    • 제23권3호
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    • pp.191-195
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    • 2013
  • 본 논문에서는 방대한 웹 자원의 연결성을 더욱 증가시키기 위해 영어 위키피디아 문서로부터 한국어 위키피디아 문서로의 교차언어 링크를 자동으로 탐색하는 방법을 제안한다. 어구의 링크확률을 대략 추정하여 사용하던 기존의 방법에 비해, 본 연구에서는 위키피디아 문서 집합으로부터 추출한 제목 목록과 링크 확률과 같은 다양한 정보들과 개체명 인식 결과를 함께 사용하여 링크가 걸릴 앵커 후보를 선택한다. 앵커 후보를 한국어 대역어로 번역한 후, 대역어에 가장 적합한 한국어 웹문서를 찾아 교차언어 링크로 설정하게 된다. 실험한 결과 MAP 수치로 0.375를 얻었다.

Sequence Specificity for DNA Interstrand cross-linking induced by anticancer drug chlorambucil

  • Yoon, Jung-Hoon;Lee, Chong-Soon
    • Archives of Pharmacal Research
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    • 제20권6호
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    • pp.550-554
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    • 1997
  • Chlorambucil is known to alkylate primarily N7 of guanine and N3 of adenine to induce DNA monofunctional adducts and interstrand cross-links (ISC). We have investigated the sequence specificity for DNA ISC induced by chlorambucil using duplex oligomers containing a defined cross-linkable sequences $ 5^{I}-A*TT, 5^{I}-G*TTor5^{I}-G*CC$ under bar which asterisk indicates the potential cross-linking site and underlined base indicates the potential cross-linking site on the opposite strand. An analysis of 20% denaturing polyacrylamide gel electrophoresis showed that chlorambucil was albe to induce DNA ISC in the duplex oligomers containing a sequence $5^I-GCC$. The formation of DNA ISC was not observed in the duplex oligomers containing sequences $5^I-ATT$. or $5^I-GTT$. These results indicate that chlorambucil induces guanine-guanine DNA ISC but not guanine-adenine or adenine-adenine DNA ISC. In addition, we have tested the ability of chlorambucil to induce DNA ISC within $5^I-GNNC$ or $5^I-GNNC$sequences using duplex oligomers containing the sequence$5^I-G^4G^3G^2^C$. The result of DNA strand cleavage assay showed that DNA ISC was formed at the $5^I-GGC$ sequence (an 1,3 cross-link, $G^1-G^3$) but not at $5^I-GGGC$ (an 1,4 cross-link, $G^1-G^4$) or $5^I-GC$ sequence (an 1,2 cross-link, $G^1-G^2$).

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개념도를 이용한 구조적 지식의 조사 연구 -초등학교 평면 도형 단원을 중심으로- (An Analysis on Structural Knowledges by Concept Maps -Focused on Plane Figures in Elementary School-)

  • 정승진;박배훈
    • 한국수학교육학회지시리즈C:초등수학교육
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    • 제2권1호
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    • pp.65-73
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    • 1998
  • The purpose of this study is to investigate significant differences of structural knowledges among the groups(high, middle, low) when the 6th grade subjects structured the concepts of the plane figures, triangle and quadrangle, by concept maps, and to analyse the features of concept maps according to hierarchy. For this purpose, the following two research contents were investigated: 1. Investigating significant differences of structural knowledge in the concepts of the plane figures using concept maps among the groups(high, middle, low). 2. Analysing the features of concept maps according to hierarchy. The structural knowledges represented on the concept maps of triangle and quadrangle which were drawn by the subjects were analysed by propositions, hierarchies, and cross-links. Subject-self Reports about how to make the concept maps were used to analyse the features of concept maps according to hierarchy. The conclusions drawn from the results were as fellows: First, there were significant differences among the groups in proposition links. Second, there wasn't my significant difference among the groups in hierarchy. Third, there were significant differences among the groups in cross-links, and Fourth, the results of analysing the concept maps by hierarchy showed that there were differences among the individuals in constructing the knowledges.

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Formation and Physical Properties of Yogurt

  • Lee, W.J.;Lucey, J.A.
    • Asian-Australasian Journal of Animal Sciences
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    • 제23권9호
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    • pp.1127-1136
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    • 2010
  • Yogurt gels are a type of soft solid, and these networks are relatively dynamic systems that are prone to structural rearrangements. The physical properties of yogurt gels can be qualitatively explained using a model for casein interactions that emphasizes a balance between attractive (e.g., hydrophobic attractions, casein cross-links contributed by calcium phosphate nanoclusters and covalent disulfide cross-links between caseins and denatured whey proteins) and repulsive (e.g., electrostatic or charge repulsions, mostly negative at the start of fermentation) forces. Various methods are discussed to investigate the physical and structural attributes of yogurts. Various processing variables are discussed which influence the textural properties of yogurts, such as total solids content, heat treatment, and incubation temperatures. A better understanding of factors contributing to the physical and structural attributes may allow manufacturers to improve the quality of yogurt.

Seismic performance of high-strength steel framed-tube structures with bolted web-connected replaceable shear links

  • Lian, Ming;Cheng, Qianqian;Guan, Binlin;Zhang, Hao;Su, Mingzhou
    • Steel and Composite Structures
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    • 제37권3호
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    • pp.323-339
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    • 2020
  • In steel framed-tube structures (SFTSs), the plastic hinges at beam-ends cannot be adequately improved because of the large cross sections of spandrel beams, which results in the lower ductility and energy dissipation capacities of traditional SFTSs. To address this drawback, high-strength steel fabricated SFTSs with bolted web-connected replaceable shear links (HSFTS-SLs) have been proposed. In this system, shear links use conventional steel and are placed in the middle of the deep spandrel beams to act as energy dissipative components. In this study, 2/3-scaled HSFTS-SL specimens were fabricated, and cyclic loading tests were carried out to study the seismic performance of both specimens. The finite element models (FEMs) of the two specimens were established and the numerical results were compared with the test results. The results showed that the specimens had good ductility and energy dissipation capacities due to the reliable deformation capacities. The specimens presented the expected failure modes. Using a shorter shear link can provide a higher load-carrying capacity and initial elastic lateral stiffness but induces lower ductility and energy dissipation capacity in HSFTS-SLs. The performance of the specimens was comparable to that of the original sub-structure specimens after replacing shear links. Additionally, the expected post-earthquake recoverability and resilience of the structures could be achieved by replacing shear links. The acceptable residual interstory drift that allows for easy replacement of the bolted web-connected shear link was 0.23%. The bolted web-connected shear links had reliable hysteretic responses and deformation capacities. The connection rotation had a notable contribution to total link rotation. The results of the numerical analysis run for the proposed FEMs were consistent with the test results. It showed that the proposed FEMs could be used to investigate the seismic performance of the HSFTS-SL.

UCI 상호참조에 기반한 참조연계시스템의 구현 (Establishment of Reference Linking Systems on UCI Cross-Reference)

  • 박승범;이상원
    • 한국IT서비스학회지
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    • 제12권1호
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    • pp.115-130
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    • 2013
  • This paper describes Cross reference services in Knowledge contents based on UCI. Cross references are effective features that can increase the value of the contents. Knowledge contents include academic papers, research reports, archives, historical and cultural heritage, and professional databases. Cross references are consists of reference-to and cited-by links which can be made by reference list in article. Some of cross reference services provided are considered. We designed cross reference services for knowledge contents in Korea and prototype services are provided. The reference linking service in the area of national R&D will enable the linking of heterogeneous information produced at different sources.

비타민 C가 in vitro 계에서 콜라겐 미숙가교 생성에 미치는 영향 (The Effect of L-Ascorbic Acid on the Formation of Immature Crosslink in Bone Collagen in vitro)

  • 김미향
    • 한국식품영양과학회지
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    • 제28권6호
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    • pp.1332-1338
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    • 1999
  • Intermolecular collagen cross links stabilize collagen fibrils and are necessary for normal tensile strength in collagen fibrils. Once the fibrils are aligned, hydroxyllysine, hydroxylysine derived aldehyde modified enzymatically, reacts with hydroxylysine to form the dehydrodihydroxylysinonorleucine (DHLNL), an immature crosslink. Pyridinoline, one of matured cross links is presumably formed nonenzymatically through condensation of DHLNL and hydroxylysine residue. It is widely distributed in hard connective tissues such as cartilage, bone and tendon. L ascorbic acid(AsA) is well known to be required for the enzymatic hydroxylation of proline and lysine in collagen fibrils. The purpose of this study is to clarify the role of AsA on the biosynthesis of DHLNL in vitro. We examined the effect of AsA on the formation of hydroxylysine and DHLNL in collagen. Pyridinoline and DHLNL were measured as a function of time. The contents of DHLNL was increased, reached maximum within 2 hr and was held until 24 hr, then it decreased slowly. On the contrary, pyridinoline increased gradually after 24 hr and continued to increase for 2 weeks. Moreover, the contents of DHLNL remarkably decreased at 60 min after incubation, the contents of DHLNL was decreased by addition of AsA or dehydroascorbic acid(DHA). These results suggest that the supplementation of AsA causes decrease in DHLNL formation and pyridinoline formed by nonenzymatic reaction of DHLNL.

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호르몬 투여가 난소를 절제한 흰쥐의 골단백질 성숙에 미치는 영향 (Effect of Hormone Replacement Therapy on the Change of Pyridinoline from Bone and Cartilage Collagen of Ovariectomized Rats)

  • 김미향;유리나;하배진;김상애;고진복
    • 한국식품영양과학회지
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    • 제26권3호
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    • pp.475-479
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    • 1997
  • A decrease in the circulating levels of estrogen, occuring as a consequence of post menopausal decline or from surgical ovariectomy, results in an accelerated loss of bone. Estrogen has been shown to stimulate lysyl oxidase activity, and the treatment with estrogen increased the pyridinium content of cortical bone. a trivalent mature cross-links collagen fibrils named pyridinoline, which is especially abundant in collagen of cartilage and bone, markedly increases with growth in humans and rats. The main aim of this study was to examine the increased bone loss caused by ovariectomy through monitoring the concentrations of the collagen and the pyridinium cross-links of collagen, pyridinoline. The ovariectomized rats, 4 weeks old, were divided at random into two or three groups of 5. Ovariectomies were carried out on both of the saline-treated group(OVX(NH)) and the estrogen-treated group(OVX(H)) using the dorsal approach and sham operations were performed on the sham-operated group(sham). They were maintained under identical conditions for 4 or 8 weeks and were allowed free access to food and water. it was observed that there was no significant difference between the control group and the sham-operated group, however, the control group had a higher content of collagen than the saline-treated group after 4 weeks and 8 weeks. Based on these results, iot is supposed that estrogen can enhance collagen synthesis and affects the pyridinoline formation in collagen fibrils through stimulating lysyl oxidase activity.

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수지 가공 면직물의 강도 회복을 위한 효소처리 연구 (Strength Restoration of The DP Finished Cotton Fabric by Enzymatic Treatment)

  • 전미선;김주혜;박명자
    • 복식문화연구
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    • 제12권5호
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    • pp.737-742
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    • 2004
  • The purpose of this study is restoration for tearing strength of the durable press (DP) finished 100% cotton fabric by enzymatic treatment. Dimethylol Dihydroxy Ethylene Urea (DMDHEU) was used as a DP finish chemical. Enzymes (cellulase, pectinase, protease, lipolase) were selected based on their specific reaction activities. Ideal application of the enzymes for this work was to remove cross-links created by DMDHEU on the surface of the fibers to offer migration property between microstructures of cellulose, yet cross-links that exist inside of the fibers are still remained to impart effect of wrinkle resistance. Physical characteristics (tearing strength, wrinkle recovery, FT-IR) of enzyme treated samples were measured and compared. It was found out that, in case of enzyme treatment, most of enzymes didn't have a great effect on tearing strength, but, in case of Protease, tearing strength increased at DMDHEU 2% treatment. As a result of an experiment on wrinkle recovery of the textiles treated with enzyme making density of DMDHEU different whenever respective experiment was made, it was discovered that density of DMDHEU increased as wrinkle recovery increased and, in the relation to enzyme treatment especially in Lipase enzyme treatment, the lesser density of DMDHEU, the more wrinkle recovery increased.

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Quality Control of Photosystem II during Photoinhibition

  • Yamamoto, Yasusi
    • Journal of Photoscience
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    • 제9권2호
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    • pp.55-58
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    • 2002
  • The reaction center Dl protein of photosystem II is the target of photodamage by excess illumination. The Dl protein is damaged by reactive oxygen species generated by photochemical reactions and then degraded by specific proteolytic enzymes. We found that the Dl protein also cross-links with the surrounding polypeptides, such as D2 and CP43 in isolated thylakoids or photosystem II-enriched membranes from spinach under the illumination with strong visible light. The cross-linking was observed in spinach leaf discs as well when they were illuminated at higher temperature (40°C). It was also shown that the cross-linked products are digested efficiently by a protease(s) in the stroma. Thus the cross-linking/digestion processes of the Dl protein seem to comprise a new pathway in the turnover of the photodamaged Dl protein. It should be noted, however, that the cross-linked products of the Dl protein and CP43 induced by endogenous cationic radicals in the donor-side photoinhibition are resistant to proteolytic digestion. Accumulation of these cross-linked products in the thylakoids may lead to the decay of the function of chloroplasts and finally to the death of plant cells. Thus, we suggest that the quality control of photosystem II, especially removal of the cross-linked products of the Dl protein, is crucial for the survival of chloroplasts under the light stress.

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