• Tuberculosis and Respiratory Diseases
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• 제84권2호
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• pp.105-114
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• 2021

Background: Complementary and alternative medicine (CAM) has been used frequently, and its use continues to increase in lung cancer patients, despite insufficient scientific of its efficacy. To investigate this situation, we analyzed the current awareness and use of CAM in Korean lung-cancer patients. Methods: This prospective survey-based study was performed at seven medical centers in South Korea between August and October 2019. The survey assessed general patient characteristics and the awareness and use of CAM. We analyzed differences in the clinical parameters of patients aware and not aware of CAM and of CAM non-users and users. Results: Of the 434 patients included in this study, 68.8% responded that they were aware of CAM and 30.9% said they had experienced it. In univariate analysis, the patients aware of CAM were younger with poor performance status, had advanced-stage lung cancer, received more systemic therapy, and received concurrent chemoradiation therapy (CCRT). By multiple logistic regression, younger age, poor performance status, advanced stage, and prior CCRT were identified as independent risk factors for CAM awareness. There were no significant differences in the general characteristics and cancer-associated clinical parameters of CAM non-users and users. Conclusion: Specific clinical parameters were associated with patients' awareness of CAM, although there were no significantly different characteristics between CAM users and non-users.

• 한국산학기술학회논문지
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• 제4권3호
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• pp.223-229
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• 2003

ICRP-60 신권고에 맞게 수정된 방사선피폭선량 계산프로그램인 K-DOSE 60을 4개 발전소 (고리, 월성, 울진, 영광)에 적용하여 주변주민 최대개인피폭선량을 평가하였다 핵종, 장기, 경로별로 결정변수값들을 도출한 결과, 경로는 성인의 경우 농작물, 유아의 경우 우유가, 핵종은 ³H, /sup 133/Xe, /sup 60/Co (고리 1,2발전소), /sup 14/C, /sup 41/Ar(월성 1,2발전소)로 나타났으며, 모든 장기에 대한 피폭선량차이가 매우 작았다. "출력 대 입력" 변동에 근거한 민감도 분석결과, 핵종의 화학적 형태가 타 입력변수들보다 10² factor만큼 높은 민감도를 보였으며, 전이/농축계수에 의한 민감도는 섭취량이나 방출량의 그것에 비하여 상대적으로 매우 낮았다. PCC를 이용한 상관성 민감도의 경우는 4가지 입력변수 모두 0.97 이상의 높은 상관성을 보였다.

• 한국터널지하공간학회 논문집
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• 제6권2호
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• pp.129-139
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• 2004

터널의 환기설계에 관련하여 종류식과 횡류식의 환기용량의 산정을 위해서 필요한 제반 가정들을 검토하였고, 종류식 설계에서의 최종 값인 임계유속 산정을 위한 몇 가지의 공식을 분석하였다. 이를 토대로 특정 공식을 개선하기 위한 방안을 실험결과를 토대로 제시하였다. 횡류식 설계에서 국제적으로 사용되고 있는 용량산정에 관한 지침은 화재공학적 의미가 전혀 없으며 관행적으로 적용되어 온 것임을 알 수 있었다. 뿐만 아니라 기존의 횡류식 환기설계에는 설계개념조차 명확하지 않음을 입증하였다. 즉 횡류식 시스템에서는 종류식에서의 "연기의 역류 방지를 위한 최소 유속의 유지"라는 개념조차 없이 환기용량이 결정되어 왔으며, 이것은 터널의 화재환기가 오염물질의 환기로부터 시작되어 정확한 화재공학적 분석이 결여되었기 때문이다. 이러한 문제를 해결하기 위한 시도로 횡류식 환기의 설계개념으로서 연기전파거리와 연기축적을 제안하였다. 축소모델 터널을 이용하여 연기전파거리에 관한 실험결과를 제시하였고, 이를 이용하여 기존의 관행대로 설계된 유럽의 터널들에 적용하였을 때 안전성에 문제가 있음을 보였다.

• Tuberculosis and Respiratory Diseases
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• 제85권2호
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• pp.175-184
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• 2022

Background: Post-tuberculosis (TB) sequelae is a commonly encountered clinical entity, especially in high TB burden countries. This may represent chronic anatomic sequelae of previously treated TB, with frequent symptomatic presentation. This pilot study was aimed to investigate the pulmonary functions and systemic inflammatory markers in patients with post-TB sequelae (PTBS) and to compare them with post-TB without sequelae (PTBWS) participants and healthy controls. Methods: A total of 30 participants were enrolled, PTBS (n=10), PTBWS (n=10), and healthy controls (n=10). Pulmonary function tests included spirometry and measurement of airway impedance by impulse oscillometry. Serum levels of matrix metalloproteinase (MMP)-1, transforming growth factor-β, and interferon-γ were estimated. Results: Slow vital capacity (SVC), forced vital capacity (FVC), forced expiratory volume in 1 second (FEV₁), FEV₁/FVC, and peak expiratory flow were significantly lower in PTBS as compared to controls. SVC and FEV₁ were significantly less in PTBS as compared to PTBWS. Total airway impedance (Z₅), total airway resistance (R₅), central airway resistance (R₂₀), area of reactance (Ax), and resonant frequency (Fres) were significantly higher and respiratory reactance at 5 and 20 Hz (X₅, X₂₀) were significantly lower in PTBS as compared to PTBWS. Spirometry parameters correlated with impulse oscillometry parameters in PTBS. Serum MMP-1 level was significantly higher in PTBS as compared to other groups. Conclusion: Significant pulmonary function impairment was observed in PTBS, and raised serum MMP-1 levels compared with PTBWS and healthy controls. Follow-up pulmonary function testing is recommended after treatment of TB for early diagnosis and treatment of PTBS.

• 대한전자공학회논문지
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• 제26권11호
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• pp.1658-1665
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• 1989

Reactor design considerations over several critical parameters for a planar type reactive ion etcher are given. The etch uniformity is taken as a principal design constraint. The characteristics of economicaly available vacuum pumping system are taken as practical design constraints. A set of theoretical conditions on the chamber geometry and on the gas delivery and vacuum system, that satisfy the design constraints, are derived from basic properties of RF glow discharge and gas dynamics. The theoretical results are applied to decide design parameters of a practical single-wafer-per-chamber planar type reactive ion etching machine.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2004년도 가을 학술발표회 논문집
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• pp.445-450
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• 2004

Tunnel fire accident is one of the critical railway accidents, together with collision and derailment. For the safe operation many tunnel design guidelines are proposed but many Korean railway tunnels do not satisfy these guidelines. For the safety improvement, current safety level is estimated in this study. But so many uncertainties in major input parameters make the safety estimation difficult. In this study, probabilistic techniques are applied for the consideration of uncertainties in major input parameters. As results of this study, probabilistic safety estimation code is developed.

• 천문학회보
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• 제42권2호
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• pp.57.3-58
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• 2017

We report the detailed design of an unprecedented wideband(band7+8) corrugated feed horn in ASTE focal plane array aiming for future ALMA receiver. We have found that such design constraints as return loss, cross-polarization level, beam width and phase curvature can be controlled by optimizing critical corrugation parameters at the throat and flare region of the horn. The success of optimization manifest itself through simulated aperture effciency over 80 % at the entire frequency range. Physical implications of the resulting corrugation parameters are discussed.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2001년도 가을 학술발표회 논문집
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• pp.253-260
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• 2001

In a structural inverse problem with a limitation to the number of measuring degrees of freedom, the selection of optimal sensor locations (OSL) is critical for a good result. The current research proposes and a new OSL method and compares it with a widely used OSL method. The proposed method utilizes the sensitivity of eigenvectors with respect to the structural parameters. A simulation study for a tower structure is carried out. The structural parameters are estimated by a SI method. The influences of OSL on SI results are investigated.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2003년도 춘계학술대회논문집
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• pp.489-494
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• 2003

Vibration localization characteristics of open loop repeated structures with mistuning are investigated in this paper. Mistuning of a periodic structure often creates significant non-uniformity in vibration responses. As a result of the localization, critical fatigue problems often occur in repeated structures. Therefore, it is of great importance to predict the vibration response of the mistuned repeated structures accurately. In this paper, a simplified model for the open-loop repeated structure is introduced and dimensionless parameters which influence the localization characteristics are identified. The effects of the parameters on the localization characteristics are investigated through numerical study.

• Wind and Structures
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• 제32권1호
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• pp.19-30
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• 2021

This study presents buckling analysis of a simply supported sandwich plate with functionally graded porous layers. In the kinematic relation of the plate, a hyperbolic shear displacement model is used. The governing equations of the problem are derived by using the principle of virtual work. In the solution of the governing equations, the Navier procedure is implemented. In the porosity effect, four different porosity types are used for functionally graded sandwich layers. In the numerical examples, the effects of the porosity parameters, porosity types and geometry parameters on the critical buckling of the functionally graded sandwich plates are investigated.