• Title/Summary/Keyword: critical parameters

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Reliability of analytical models for the prediction of out-of-plane capacity of masonry infills

  • Pasca, Monica;Liberatore, Laura;Masiani, Renato
    • Structural Engineering and Mechanics
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    • v.64 no.6
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    • pp.765-781
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    • 2017
  • The out-of-plane response of infill walls has recently gained a growing attention and has been recognised fundamental in the damage assessment of reinforced concrete and steel framed buildings subjected to seismic loads. The observation of damage after earthquakes highlighted that out-of-plane collapse of masonry infills may occur even during seismic events of low or moderate intensity, causing both casualty risks and unfavourable situations affecting the overall structural response. Even though studies concerning the out-of-plane behaviour of infills are not as many as those focused on the in-plane response, in the last decades, a substantial number of researches have been carried out on the out-of-plane behaviour of infills. In this study, the out-of-plane response is investigated considering different aspects. First, damages observed after past earthquakes are examined, with the aim of identifying the main parameters involved and the most critical configurations. Secondly, the response recorded in about 150 experimental tests is deeply examined, focusing on the influence of geometrical characteristics, boundary conditions, prior in-plane damage, presence of reinforcing elements and openings. Finally, different theoretical capacity models and code provisions are discussed and compared, giving specific attention to those based on the arching theory. The reliability of some of these models is herein tested with reference to experimental results. The comparison between analytically predicted and experimental values allows to appreciate the extent of approximation of such methods.

Conjugated Linoleic Acid as a Key Regulator of Performance, Lipid Metabolism, Development, Stress and Immune Functions, and Gene Expression in Chickens

  • Choi, Yang-Ho
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.3
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    • pp.448-458
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    • 2009
  • It has been well documented from animal and human studies that conjugated linoleic acid (CLA) has numerous beneficial effects on health. In chickens, CLA exerts many effects on performance ranging from egg quality and yolk lipids to meat quality. Although there are several CLA isomers available, not all CLA isomers have the same incorporation rates into egg yolk: cis-9,trans-11 and trans-10,cis-12 CLA isomers are more favorably deposited into egg yolk than other isomers investigated, but of the two isomers, the former has a higher incorporation rate than the latter. CLA alters the amounts and profiles of lipids in plasma, muscles and liver. Furthermore, increased liver weight was reported in chickens fed dietary CLA. As observed in egg yolk, marked reduction in intramuscular lipids as well as increased protein content was observed in different studies, leading to elevation in protein-to-fat ratio. Inconsistency exists for parameters such as body weight gain, feed intake, feed conversion ratio, egg production rate and mortality, depending upon experimental conditions. One setback is that hard-cooked yolks from CLA-consuming hens have higher firmness as refrigeration time and CLA are increased, perhaps owing to alterations in physico-chemistry of yolk. Another is that CLA can be detrimental to hatchability when provided to breeders: eggs from these breeders have impaired development in embryonic and neonatal stages, and have increased and decreased amounts of saturated fatty acids and monounsaturated fatty acids (MUFAs), respectively. Thus, both problems can be fully resolved if dietary sources rich in MUFAs are provided together with CLA. Emerging evidence suggests that CLA exerts a critical impact on stress and immune functions as it can completely nullify some of the adverse effects produced by immune challenges and reduce mortality in a dose-dependent manner. Finally, CLA is a key regulator of genes that may be responsible for lipid metabolism in chickens. CLA down-regulates both expression of the gene encoding stearoyl-CoA desaturase-1 and its protein activity in the chicken liver while up-regulating mRNA of sterol regulatory element-binding protein-l.

Optimization of Direct Lysine Decarboxylase Biotransformation for Cadaverine Production with Whole-Cell Biocatalysts at High Lysine Concentration

  • Kim, Hyun Joong;Kim, Yong Hyun;Shin, Ji-Hyun;Bhatia, Shashi Kant;Sathiyanarayanan, Ganesan;Seo, Hyung-Min;Choi, Kwon Young;Yang, Yung-Hun;Park, Kyungmoon
    • Journal of Microbiology and Biotechnology
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    • v.25 no.7
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    • pp.1108-1113
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    • 2015
  • Cadaverine (1,5-diaminopentane) is an important industrial chemical with a wide range of applications. Although there have been many efforts to produce cadaverine through fermentation, there are not many reports of the direct cadaverine production from lysine using biotransformation. Whole-cell reactions were examined using a recombinant Escherichia coli strain overexpressing the E. coli MG1655 cadA gene, and various parameters were investigated for the whole-cell bioconversion of lysine to cadaverine. A high concentration of lysine resulted in the synthesis of pyridoxal-5'-phosphate (PLP) and it was found to be a critical control factor for the biotransformation of lysine to cadaverine. When 0.025 mM PLP and 1.75 M lysine in 500 mM sodium acetate buffer (pH6) were used, consumption of 91% lysine and conversion of about 80% lysine to cadaverine were successfully achieved.

A Study on the Characteristics of an Air Cavity Attached Under a Flat Plate (평판에 형성된 공기공동 특성에 관한 연구)

  • Kim, Jong-Hyun;Oh, Jae-Young;Seo, Dae-Won;Lee, Seung-Hee
    • Journal of the Society of Naval Architects of Korea
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    • v.48 no.5
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    • pp.396-403
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    • 2011
  • The concept of an air lubrication has long been an object of attention since it can be utilized to reduce the frictional resistance, and what is more, it is eco-friendly. The present study examines the basic characteristics of an air cavity with intention of applying the air lubrication technology to the reduction of the resistance of a ship without excessive power increment. For the purpose, an air cavity was created at the bottom of a flat plate by injecting air behind a backward step and the hydrodynamic properties of the air cavity and the surrounding flow has been investigated experimentally and numerically. The influence of the step height and the air flow rate have been more carefully studied since they are presumed to be the main parameters affecting the characteristics of an air cavity. The results indicates that the shapes of the air cavities attached on the flat plate become "U" or "V" type depending on the incoming flow velocity and air flow rate. The study also confirms that the length of the air cavity increases with increase in air flow rate but there is a certain critical limit in the flow rate above which increase in the air cavity length is no more evident.

Reactor Neutron Activation Analysis by a Single Comparator Method

  • Lee, Chul
    • Nuclear Engineering and Technology
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    • v.5 no.2
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    • pp.137-149
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    • 1973
  • A method of activation analysis, based on the irradiation and counting of an iron wire which contains manganese impurity as the single comparator. has been elaborated by critical evaluation of nuclear data involved in activation and activity measurement. The variation of effective cross section is investigated as a function of the spectral index and other parameters such as a measure of the proportion of epithermal neutrons in the reactor spectrum. The errors induced by shifts in the neutron spectrum in the irradiation positions are discussed. The known amount of each element is irradiated simultaneously together with the single comparator, and the obtained values are compared with the known amount of each element. The results show that en general the random errors are not greater than those obtained by using the conventional relative method, but the systematic errors were up to about 20%. This method is applied to the determinations of fourteen rare earth elements in monazite as well as other seven elements in the standard kale powder. The satisfactory reproducibility of the present method makes possible the determination of the elements with an accuracy attainable with the conventional relative method.

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OECD/NEA BENCHMARK FOR UNCERTAINTY ANALYSIS IN MODELING (UAM) FOR LWRS - SUMMARY AND DISCUSSION OF NEUTRONICS CASES (PHASE I)

  • Bratton, Ryan N.;Avramova, M.;Ivanov, K.
    • Nuclear Engineering and Technology
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    • v.46 no.3
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    • pp.313-342
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    • 2014
  • A Nuclear Energy Agency (NEA), Organization for Economic Co-operation and Development (OECD) benchmark for Uncertainty Analysis in Modeling (UAM) is defined in order to facilitate the development and validation of available uncertainty analysis and sensitivity analysis methods for best-estimate Light water Reactor (LWR) design and safety calculations. The benchmark has been named the OECD/NEA UAM-LWR benchmark, and has been divided into three phases each of which focuses on a different portion of the uncertainty propagation in LWR multi-physics and multi-scale analysis. Several different reactor cases are modeled at various phases of a reactor calculation. This paper discusses Phase I, known as the "Neutronics Phase", which is devoted mostly to the propagation of nuclear data (cross-section) uncertainty throughout steady-state stand-alone neutronics core calculations. Three reactor systems (for which design, operation and measured data are available) are rigorously studied in this benchmark: Peach Bottom Unit 2 BWR, Three Mile Island Unit 1 PWR, and VVER-1000 Kozloduy-6/Kalinin-3. Additional measured data is analyzed such as the KRITZ LEU criticality experiments and the SNEAK-7A and 7B experiments of the Karlsruhe Fast Critical Facility. Analyzed results include the top five neutron-nuclide reactions, which contribute the most to the prediction uncertainty in keff, as well as the uncertainty in key parameters of neutronics analysis such as microscopic and macroscopic cross-sections, six-group decay constants, assembly discontinuity factors, and axial and radial core power distributions. Conclusions are drawn regarding where further studies should be done to reduce uncertainties in key nuclide reaction uncertainties (i.e.: $^{238}U$ radiative capture and inelastic scattering (n, n') as well as the average number of neutrons released per fission event of $^{239}Pu$).

Seismic response of masonry infilled RC frames: practice-oriented models and open issues

  • Lima, Carmine;De Stefano, Gaetano;Martinelli, Enzo
    • Earthquakes and Structures
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    • v.6 no.4
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    • pp.409-436
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    • 2014
  • Although it is widely accepted that the interaction -between masonry infill and structural members significantly affects the seismic response of reinforced concrete (RC) frames, this interaction is generally neglected in current design-oriented seismic analyses of structures. Moreover, the role of masonry infill is expected to be even more relevant in the case of existing frames designed only for gravitational loads, as infill walls can significantly modify both lateral strength and stiffness. However, the additional contribution to both strength and stiffness is often coupled to a modification of the global collapse mechanisms possibly resulting in brittle failure modes, generally related to irregular distributions of masonry walls throughout the frame. As a matter of principle, accurate modelling of masonry infill should be at least carried out by adopting nonlinear 2D elements. However, several practice-oriented proposals are currently available for modelling masonry infill through equivalent (nonlinear) strut elements. The present paper firstly outlines some of the well-established models currently available in the scientific literature for modelling infill panels in seismic analyses of RC frames. Then, a parametric analysis is carried out in order to demonstrate the consequences of considering such models in nonlinear static and dynamic analyses of existing RC structures. Two bay-frames with two-, three- and four-storeys are considered for performing nonlinear analyses aimed at investigating some critical aspects of modelling masonry infill and their effects on the structural response. Particularly, sensitivity analyses about specific parameters involved in the definition of the equivalent strut models, such as the constitutive force-displacement law of the panel, are proposed.

Computational design of mould sprue for injection moulding thermoplastics

  • Lakkannan, Muralidhar;Mohan Kumar, G.C.;Kadoli, Ravikiran
    • Journal of Computational Design and Engineering
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    • v.3 no.1
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    • pp.37-52
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    • 2016
  • To injection mould polymers, designing mould is a key task involving several critical decisions with direct implications to yield quality, productivity and frugality. One prominent decision among them is specifying sprue-bush conduit expansion as it significantly influences overall injection moulding; abstruseness anguish in its design criteria deceives direct determination. Intuitively designers decide it wisely and then exasperate by optimising or manipulating processing parameters. To overwhelm that anomaly this research aims at proposing an ideal design criteria holistically for all polymeric materials also tend as a functional assessment metric towards perfection i.e., criteria to specify sprue conduit size before mould development. Accordingly, a priori analytical criterion was deduced quantitatively as expansion ratio from ubiquitous empirical relationships specifically a.k.a an exclusive expansion angle imperatively configured for injectant properties. Its computational intelligence advantage was leveraged to augment functionality of perfectly injecting into an impression gap, while synchronising both injector capacity and desired moulding features. For comprehensiveness, it was continuously sensitised over infinite scale as an explicit factor dependent on in-situ spatio-temporal injectant state perplexity with discrete slope and altitude for each polymeric character. In which congregant ranges of apparent viscosity and shear thinning index were conceived to characteristically assort most thermoplastics. Thereon results accorded aggressive conduit expansion widening for viscous incrust, while a very aggressive narrowing for shear thinning encrust; among them apparent viscosity had relative dominance. This important rationale would certainly form a priori design basis as well diagnose filling issues causing several defects. Like this the proposed generic design criteria, being simple would immensely benefit mould designers besides serve as an inexpensive preventive cliché to moulders. Its adaption ease to practice manifests a hope of injection moulding extremely alluring polymers. Therefore, we concluded that appreciating injectant's polymeric character to design exclusive sprue bush offers a definite a priori advantage.

Application of cost-sensitive LSTM in water level prediction for nuclear reactor pressurizer

  • Zhang, Jin;Wang, Xiaolong;Zhao, Cheng;Bai, Wei;Shen, Jun;Li, Yang;Pan, Zhisong;Duan, Yexin
    • Nuclear Engineering and Technology
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    • v.52 no.7
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    • pp.1429-1435
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    • 2020
  • Applying an accurate parametric prediction model to identify abnormal or false pressurizer water levels (PWLs) is critical to the safe operation of marine pressurized water reactors (PWRs). Recently, deep-learning-based models have proved to be a powerful feature extractor to perform high-accuracy prediction. However, the effectiveness of models still suffers from two issues in PWL prediction: the correlations shifting over time between PWL and other feature parameters, and the example imbalance between fluctuation examples (minority) and stable examples (majority). To address these problems, we propose a cost-sensitive mechanism to facilitate the model to learn the feature representation of later examples and fluctuation examples. By weighting the standard mean square error loss with a cost-sensitive factor, we develop a Cost-Sensitive Long Short-Term Memory (CSLSTM) model to predict the PWL of PWRs. The overall performance of the CSLSTM is assessed by a variety of evaluation metrics with the experimental data collected from a marine PWR simulator. The comparisons with the Long Short-Term Memory (LSTM) model and the Support Vector Regression (SVR) model demonstrate the effectiveness of the CSLSTM.

Effects of Surfactant Molecules’ Head- and Tail-groups on the Solubilization of p-Chlorobenzoic Acid (p-클로로벤조산의 가용화에서 계면활성제분자의 머리-그룹과 꼬리-그룹이 미치는 효과)

  • Lee, Byung-Hwan;Lee, Nam-Min
    • Journal of the Korean Chemical Society
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    • v.59 no.5
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    • pp.379-386
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    • 2015
  • The solubilization of p-chlorobenzoic acid in aqueous solutions of pure cationic, nonionic, amphoteric, and their mixed surfactant systems have been measured by the UV-Vis spectrophotometric method. The effects of hydrophobic tail-group with different chain length and the hydrophilic head-group on the solubilization of p-chlorobenzoic acid have been studied and also thermodynamic parameters have been calculated from the dependence of Ks values on the temperature. The results show that the values of ΔGo for the solubilization by all surfactant systems are negative and the values of ΔHo and ΔSo are all positive.