• The Korean journal of internal medicine
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• 제39권3호
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• pp.477-487
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• 2024

Background/Aims: Risk factors for progression to critical illness in hospital-acquired coronavirus disease 2019 (COVID-19) remain unknown. Here, we assessed the incidence and risk factors for progression to critical illness and determined their effects on clinical outcomes in patients with hospital-acquired COVID-19. Methods: This retrospective cohort study analyzed patients admitted to the tertiary hospital between January 2020 and June 2022 with confirmed hospital-acquired COVID-19. The primary outcome was the progression to critical illness of hospital-acquired COVID-19. Patients were stratified into high-, intermediate-, or low-risk groups by the number of risk factors for progression to critical illness. Results: In total, 204 patients were included and 37 (18.1%) progressed to critical illness. In the multivariable logistic analysis, patients with preexisting respiratory disease (OR, 3.90; 95% CI, 1.04-15.18), preexisting cardiovascular disease (OR, 3.49; 95% CI, 1.11-11.27), immunocompromised status (OR, 3.18; 95% CI, 1.11-9.16), higher sequential organ failure assessment (SOFA) score (OR, 1.56; 95% CI, 1.28-1.96), and higher clinical frailty scale (OR, 2.49; 95% CI, 1.62-4.13) showed significantly increased risk of progression to critical illness. As the risk of the groups increased, patients were significantly more likely to progress to critical illness and had higher 28-day mortality. Conclusions: Among patients with hospital-acquired COVID-19, preexisting respiratory disease, preexisting cardiovascular disease, immunocompromised status, and higher clinical frailty scale and SOFA scores at baseline were risk factors for progression to critical illness. Patients with these risk factors must be prioritized and appropriately isolated or treated in a timely manner, especially in pandemic settings.

• Acute and Critical Care
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• 제33권4호
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• pp.269-270
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• 2018

• Tuberculosis and Respiratory Diseases
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• 제65권3호
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• pp.239-242
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• 2008

외인성 지방성 폐렴은 자세한 병력 청취 없이는 의심하기 힘든 비교적 드문 질환이다. 저자들은 비특이적인 임상 증상과 방사선 소견을 보인 환자에서 스쿠알렌을 섭취한 과거력에 주목하였으며 외인성 지방성 폐렴을 의심 하에 기관지폐세척술 및 폐 생검을 통하여 확진하였다.

• 한국임상수의학회지
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• 제22권3호
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• pp.198-201
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• 2005

이 연구의 목적은 BUN 및 혈청 creatining, total protein, albumin과 glucose의 장기간에 걸친 개체 내 변이를 산정하여, 각각의 critical difference를 구성하는 것이다. 임상적으로 건강한 20마리의 개에서 일주일에 한번씩 총 8주간 채혈하여, 장기간에 걸친 개체 내 변이를 구하고, critical difference를 산출하였다. BUN은 9.01 mg/dl, 혈청 creatining은 0.52 mg/dl, total protein은 0.99 g/dl, albumin은 0.39 g/dl, glucose는 20.64 mg/dl로 critical difference가 산출되었다. 동일한 개에서 연속적으로 측정된 검사항목 치가 critical value보다 차이가 적으면, 이 차이는 생리적인 변화에 기인한다고 할 수 있으며, critical value보다 차이가 크면, 다른 요인, 즉 질병의 진행이나 다른 동반된 질병의 존재를 의미한다고 할 수 있다.

• 한국지반공학회논문집
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• 제19권1호
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• pp.61-75
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• 2003

한계상태 토질역학을 사질토의 전단거동에 대한 적용을 용이하게 하기 위해서, 표준삼축 시험으로부터 사질토에서의 한계상태정수 결정에 관하여 종합적인 고찰을 실시하였다. 첫째로, 문헌에 있는 어휘론적인 차이점들을 명확히 함으로써, 한계상태는 대변형에서의 궁극적인 최종상태를 나타냄을 추론하였다. 둘째로, 한계상태정수의 특성들에 관하여 검토하였고, 초기상태, 구주 하중조건 및 배수조건에 따른 한계상태선의 유일성과 유사한계상태조건의 민감성을 검증하였다. 셋째로, 한계상태정수로부터 액상화후 전단강도 즉 액상화된 흙에서의 신뢰할 수 있는 궁극적인 전단강도를 산정하기 위하여 한계상태 토질역학을 예제로서 적용하였다.

• 한국수학교육학회지시리즈A:수학교육
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• 제50권1호
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• pp.69-87
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• 2011

The aim of this research is to develop a 'program which improves critical thinking' to improve elementary school students' mathematical thinking, and investigate the effect of program by applying and verifying the program. In order to achieve the objective, the author determined the factors of critical thinking capabilities matched to the discipline of mathematics, and accordingly designed relevant programs and test questions for critical thinking skills which contributes to improving the critical thinking of elementary school students, and thus applied the program the developed program of improving the critical thinking to both preliminary and main experiments, which verified the effects of the test method. The following results have been acquired through this research : In the preliminary inspection that this researcher has developed, it was able to predict that 'the program which improves critical thinking' would have a positive influence on the students' critical thinking. In the main experiment which was performed after modifying and supplementing it, the result showed that the program had a positive influence on the students' critical thinking.

• Earthquakes and Structures
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• 제18권1호
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• pp.45-56
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• 2020

The application of critical excitation method with displacement-based objective function for multi degree of freedom (MDOF) systems is investigated. To this end, a new critical excitation method is developed to find the critical input motion of a MDOF system as a synthetic accelerogram. The upper bound of earthquake input energy per unit mass is considered as a new constraint for the problem, and its advantages are discussed. Considering this constraint, the critical excitation method is then used to generate synthetic accelerograms for MDOF models corresponding to three shear buildings of 10, 16, and 22 stories. In order to demonstrate the reliability of generated accelerograms to estimate dynamic response of the structures, three target ground motions with considerable level of energy contents are selected to represent "real critical excitation" of each model, and the method is used to re-generate these ground motions. Afterwards, linear dynamic analyses are conducted using these accelerograms along with the generated critical excitations, to investigate the key parameters of response including maximum displacement, maximum interstory drift, and maximum absolute acceleration of stories. The results show that the generated critical excitations can make an acceptable estimate of the structural behavior compared to the target ground motions. Therefore, the method can be reliably implemented to generate critical excitation of the structure when real one is not available.

• 여성건강간호학회지
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• 제12권4호
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• pp.316-325
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• 2006

Purpose: The purpose of this study was to develop a Critical Pathway for Uterine Artery Embolization patients. Method: There were 6 steps that were taken. Step 1 was selecting a diagnosis, and Step 2 was organizing a development team consisting of 7 experts. Step 3 analyzed the medical records, and Step 4 drew up a preliminary Critical Pathway. Step 5 tested the clinical validity of the preliminary Critical Pathway, and Step 6 developed the final Critical Pathway. Result: The contents of the medical practices observed in the medical records were investigated in seven areas: monitoring/assessment, treatment, medication, diet, activity, consults, and education/discharge plan; and a total of 73 items was identified. The validity of the 73 items was examined by a group of specialists. 68 items were adopted, 4 items revised, 1 item removed, and 1 item was added. Using the results, a preliminary Critical Pathway was drawn up. According to the results from examining the clinical validity of the preliminary Critical Pathway with five patients for five weeks, 3 items which showed discrepancy were revised and another 3 items were added. Then, the final Critical Pathway was completed. Conclusion: This Critical Pathway needs to be clinically applied and continuously to measure its effects in terms of the length of stay, cost.effectiveness, and the patients' and staffs' satisfaction.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2003년도 추계학술대회
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• pp.484-489
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• 2003

The mass flow rate of gas flow through critical nozzle depends on the nozzle supply conditions and the cross-sectional area at the nozzle throat. In order that the critical nozzle can be operated at a wide range of supply conditions, the nozzle throat diameter should be controlled to change the flow passage area. This can be achieved by means of a variable critical nozzle. In the present study, both experimental and computational works are performed to develop variable critical nozzle. A cone-cylinder with a diameter of d is inserted into conventional critical nozzle. It can move both upstream and downstream, thereby changing the cross-sectional area of the nozzle throat. Computational work using the axisymmetric, compressible Navier-Stokes equations is carried out to simulate the variable critical nozzle flow. An experiment is performed to measure the mass flow rate through variable critical nozzle. The present computational results are in close agreement with measured ones. The boundary layer displacement and momentum thickness are given as a function of Reynolds number. An empirical equation is obtained to predict the discharge coefficient of variable critical nozzle.

• 수산해양교육연구
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• 제19권2호
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• pp.206-218
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• 2007

The purpose of this study was to investigate effects of critical thinking dispositions on vocational personalities in university students. Subjects were 111 University students in Busan. The questionnaire used in this research were Holland's Vocational Personality Questionnaire and California Critical Thinking Disposition Inventory. The results were analyzed by correlation analysis and enter multiple regression using the SPSS statistical package (SPSS for windows 12.0; SPSS Inc., Chicago, IL, USA). The study results were as follow: First, the students had much more S and R vocational personality characteristics than the others in vocational personality characteristics and had higher inquisitiveness and self-confidence scores than the others in critical thinking dispositions. Second, there were significant relationships between vocational personality types and critical thinking dispositions. Third, some of the vocational personality types were affected by the critical thinking dispositions. Especially I, E, and C personality of vocational personalities were prospected by critical thinking dispositions. Therefore, It's necessary that we understand the relationships between vocational personality types and critical thinking dispositions. Also we have to think over how to development career programs for university students to match to the learner's vocational personality type and critical thinking dispositions.