• 한국유체기계학회 논문집
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• 제11권1호
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• pp.9-17
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• 2008

A numerical study for three-dimensional laminar flow in the entrance region of helical tubes connected with straight ones is carried out to investigate the effects of Reynolds number, pitch and curvature ratio on the oscillation periods of the flow. The fully elliptic governing equations were solved by means of a finite volume method. The fully developed laminar flow boundary condition was applied at the straight tube inlet. This results cover a curvature ratio range of 1/10${\sim}$1/320, a pitch range of 0.0${\sim}$3.2, and a Reynolds number range of 62.5${\sim}$2000. A comparison is made with previous experimental correlations and numerical data. The developments of velocity, local and average friction factors are discussed. The average friction factors are oscillatory in the entrance region of helical pipes. It has been found that the angle required for the flow to be similarly developed is most affected by the curvature ratio. The pitch and Reynolds number do not have any significant effect on the angle. The characteristic angle ${\phi}_c(={\phi}/sqrt{\delta})$, or the characteristic length to diameter ratio $s_c(=l\sqrt{\delta} cos(atan{\lambda})/d)$, can be useful to represent the development of flow in helical tubes. As the pitch increases and as the curvature ratio and Reynolds number decrease, the amplitude and the number of flow oscillations along the main streamwise direction decrease.

• Structural Engineering and Mechanics
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• 제25권4호
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• pp.481-500
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• 2007

The dynamic instability of doubly curved panels, subjected to non-uniform tensile in-plane harmonic edge loading $P(t)=P_s+P_d\;{\cos}{\Omega}t$ is investigated. The present work deals with the problem of the occurrence of combination resonances in contrast to simple resonances in parametrically excited doubly curved panels. Analytical expressions for the instability regions are obtained at ${\Omega}={\omega}_m+{\omega}_n$, (${\Omega}$ is the excitation frequency and ${\omega}_m$ and ${\omega}_n$ are the natural frequencies of the system) by using the method of multiple scales. It is shown that, besides the principal instability region at ${\Omega}=2{\omega}_1$, where ${\omega}_1$ is the fundamental frequency, other cases of ${\Omega}={\omega}_m+{\omega}_n$, related to other modes, can be of major importance and yield a significantly enlarged instability region. The effects of edge loading, curvature, damping and the static load factor on dynamic instability behavior of simply supported doubly curved panels are studied. The results show that under localized edge loading, combination resonance zones are as important as simple resonance zones. The effects of damping show that there is a finite critical value of the dynamic load factor for each instability region below which the curved panels cannot become dynamically unstable. This example of simultaneous excitation of two modes, each oscillating steadily at its own natural frequency, may be of considerable interest in vibration testing of actual structures.

• Archives of Pharmacal Research
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• 제20권5호
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• pp.459-464
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• 1997

The human liver cDNA clone UDPGTh2, encoding a liver UDP-glucuronosyltransferase (UDPGT) was isolated from a .gamma. gt 11 cDNA library by hybridization to mouse transferase cDNA clone, UDPGTm1. UDPGTh2 encoded a 529 amino acid protein with an amino terminus membrane-insertion signal peptide and a carboxyl terminus membrane-spanning region. There were three potential asparagine-linked glycosylation sites at residues 67, 68, and 315. In order to obtain UDPGTh2 protein encoded from cloned human liver UDP-glucuronosyltransferase cDNA, the clone was inserted into the pSVL vector (pUDPGTh2) and expressed in COS 1 cells. The presence of a transferase with Mr-52,000 in transfected cells cultured in the presence of $[^{35}S]$ methionine was shown by immunocomplexed products with goat antimouse transferase IgG and protein A-Sepharose and analysis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and autoradiography. The expressed UDPGT was a glycoprotein as indicated by electrophoretic mobility shift in Mr-3,000-4,000 when expressed in the presence of tunicamycin. The extent of glycosylation was difficult to assess, although one could assume that glycosyl structures incorporated at the level of endoplasmic reticulum were always the core oligosaccharides. Thus, it is likely that at least two moieties inserted can account for the shift of Mr-3,000-4,000. This study demonstrates the cDNA and deduced amino acid sequence of human liver UDP-glucuronosyltransferase cDNA, UDPGTh2.

• 농촌계획
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• 제20권3호
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• pp.67-74
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• 2014

The purpose of this study is to estimate regional economic effects of spatial diffusion of wildfire using Cobb-Douglas production function of agriculture and forestry. The analysis is applied to Gangwon and Gyeongbuk provinces where are the most damaged of wildfire in Korea. The damaged areas are derived from multiplied by the occurrence probability of wildfire and diffusion areas of wildfire for micro-spatial unit level with ArcGIS techniques. The models of wildfire provides that the spatial diffusion of wildfire increases with the rising of highest temperature and average wind speed. Through the production function, value added of Agriculture and Forest sectors get damaged where the Cos-converted slope aspect of mountains are toward the South. The production model provides reductions of regional value added by increasing damaged areas of wildfire. It reveals that the most damaged region is Andong city in Gyeongbuk province, where value added loss is 1.25 billion Won, which is about 0.72% of total value added in agriculture and forestry of the city. As a view of policy makers, it needs to be considered to establish prevention policies against wildfires because regional economic losses from wildfire are depending on geographical conditions and performances of the major industry related to wildfire's diffusion such as agriculture or tourism sector according to the result of analysis.

• 대한의생명과학회지
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• 제12권4호
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• pp.303-310
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• 2006

Ankyrins are a ubiquitously expressed family of intracellular adaptor proteins involved in targeting diverse proteins to specialized membrane domains in both the plasma membrane and the endoplasmic reticulum. We described here that the C-terminal domain of ankyrin-B interact specifically with Z-line portion of titin in yeast two-hybrid analysis, in vitro pull-down assays and localization experiments in COS-7 cells. In this study we provide the first experimental evidence that Z-line portion of titin is necessary for the localization of ankyrin-B and ankyrin-B links between the sarcolemma and the myofibril in costameres.

• 복식
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• 제38권
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• pp.17-29
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• 1998

The purpose of this paper is to explore a new methodology for the historiography of Korean cos-tumes. In particular, I focus on the possibility for systematic, historical methods appropriate for the history of Korean costumes. First, I characterize the general historiography of costumes as involving two aspects-one as the social science and the other as historical science(Geschichteswissenschaft). My contention is that any historical study of costume should be established on the intersection of social and historical studies, and their entangling relations with many a neighboring field of sciences. It requires in other words, an interdisciplinary approach that combines various methodologies of social sciences as well as those of history. Second, I present an overall review of the historical methodology with a special emphasis on the“Quellenkunde”of orthodox historiography. Building on the review, third, I pay attention to recent innovations in historical methodologies, such as“New History”that draws on history, sociology and social history, and their applicability to the history of Korean costmes. In this regards. I adress among others, the following theoretical perspectives : 1) comparioson and comparative history, 2) the formatived and paternal approaches toward the history of costume, 3) particulartiy and universality of Korean costume. I conclued that the history of Korean costumes should broaden its theoretical horizon in order to accomodate a wider range of research agenda, including costumes of neighboring cultures, while remaining sensitive to new theories and methods of the neighboring social historical sciences. For this purpose, it is emphasized that an international collaboration among researchers of the region, as well as that across the different disciplinnary boundaries, is indispensable for successful studies that can embrace diverse fields and areas.

• 한국지능시스템학회:학술대회논문집
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• 한국퍼지및지능시스템학회 1997년도 춘계학술대회 학술발표 논문집
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• pp.98-103
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• 1997

Defuzzification plays a great role in fuzzy control system. Defuzzification is a process which maps from a space defined over an output universe of discourse into a space of nonfuzzy(crisp) number. But, it's impossible to convert a fuzzy set into a numeric value without losing some information during defuzzification. Also it's very hard to find a number that best represents a fuzzy set. Many methods have been used for defuzzification but most of then were problem dependent. There has been no rule which guides how to select a method that is suitable to solve given problem. Here, we have investigated most widely used methods and we have analyzed their characteristics and evaluated them. D. Driankov and Mizumoto have suggested 5 criteria which the‘ideal’defuzzification method should satisfy. But, they didn't considered about control action. Output fuzzy set if not only a fuzzy set but also a sequence of control action. We suggested 4 new criteria which describe sequence of cont ol action from some experiments. In addition, we have compared each method in simple adaptive fuzzy control. COG(Center of Gravity), or COS(Center of Sums) methods were successful in fuzzy control. However, at transition region, MOM(Mean of Maxima) was best among others in adaptive fuzzy control.

• 천문학논총
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• 제30권2호
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• pp.121-123
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• 2015

We report our measurements of the trigonometric distance and proper motion of IRAS 20056+3350, obtained from the annual parallax of $H_2O$ masers. Our distance of $D=4.69^{+0.65}_{-0.51}kpc$, which is 2.8 times larger than the near kinematic distance adopted in the literature, places IRAS 20056+3350 at the leading tip of the Local arm and proximal to the Solar circle. We estimated the proper motion of IRAS 20056+3350 to be (${\mu}_{\alpha}cos{\delta}$, ${\mu}_{\delta}$) = ($-2.62{\pm}0.33$, $-5.65{\pm}0.52$) $mas\;yr^{-1}$ from the group motion of $H_2O$ masers, and use our results to estimate the angular velocity of Galactic rotation at the Galactocentric distance of the Sun, ${\Omega}_0=29.75{\pm}2.29km\;s^{-1}kpc^{-1}$, which is consistent with the values obtained for other tangent points and Solar circle objects.

• 수산해양기술연구
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• 제33권1호
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• pp.9-26
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• 1997

Stokes drift(SD) and Lagrangian discharge(LD) are important factors for analysis of flushing time, tidal exchange, solute transport and pollutant dispersion. The factors should be calculated using the approached method to flow phenomena. The aim of this paper re-examines the previous procedures for computing the SD and LD, and is to propose the new method approached to stratified flow field in the cross-section of coastal region, e.g. Masan Bay. The intensity of velocity near the bottom boundary layer(BBL) depends on the sea-bed irregularity in the coastal estuaries. So we calculated the depth mean velocity(DMV) considering that of BBL omitted in Kjerfve's calculation method. It revealed that BBL effect resulting in application of the bay acts largely on DMV in half more among 1l stations. The new expression of SD and LD per unit width in the cross-section using the developed DMV and proposed decomposition procedure of current were derived as follow : $$Q=u_0+\frac{1}{2}H_1{U_1cos(\varphi_h-\varphi_u)+U_3cos(\varphi_h-\varphi{ud})} LD ED SD$(Q_{skim}+Q_{sk2}) The third term, $Q_{sk2}$, on the right-hand of the equation is showed newly and arise from vertical oscillatory shear. According to the results applied in 3 cross-sections including 11 stations of the bay, the volume difference between proposed and previous SD was founded to be almost 2 times more at some stations. But their mean transport volumes over all stations are 18% less than the previous SD. Among two terms of SD, the flux of second term, $Q_{skim}$, is larger than third term, $Q_{sk2}$, in the main channel of cross-section, so that $Q_{skim}$ has a strong dependence on the tidal pumping, whereas third term is larger than second in the marginal channel. It means that $Q_{sk2}$ has trapping or shear effect more than tidal pumping phenomena. Maximum range of the fluctuation in LD is 40% as compared with the previous equations, but mean range of it is showed 11% at all stations, namely, small change. It mean that two components of SD interact as compensating flow. Therefore, the computation of SD and LD depend on decomposition procedure of velocity component in obtaining the volume transport of temporal and spacial flow through channels. The calculation of SD and LD proposed here can separate the shear effect from the previous SD component, so can be applied to non-uniform flow condition of cross-section, namely, baroclinic flow field.

• 생명과학회지
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• 제17권3호통권83호
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• pp.356-361
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• 2007

${\beta}-catenin$과 결합하는 ErbB2의 부위를 조사하기 위하여 proteasome에 의하여 분해되지 않는 ${\beta}-catenin$과 다양한 ErbB2 construct를 COS7 세포에 transfection한 후 ErbB2 단백질을 그것의 항체로 가라앉혔다. 이 때 공침한 ${\beta}-catenin$을 Western blot으로 분석하였다. C 말단에서부터 잘려진 ErbB2 단백질 중에 kinase 영역을 가지고 있는 것들만 ${\beta}-catenin$과 공침하였다. kinase 영역의 필요성을 확인하기 위하여 kinase 영역이 내부에서 제거된 ErbB2 construct를 ${\beta}-catenin$과 transfection 한 후 동일한 실험을 실시하였다. 이 실험에서 ${\beta}-catenin$는 kinase 영역이 내부적으로 제거된 ErbB2 단백질과 공침하지 않았다. 이 결과는 ${\beta}-catenin$과 결합하는 ErbB2의 위치는 kinase 영역내에 있음을 제시한다.