• Title/Summary/Keyword: cop

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DNA Binding Specificity of Proteus mirabilis Transcription Regulator (Proteus mirabilis 전사 조절 단백질의 DNA 결합 특성)

  • Gang, Jong-Back
    • Korean Journal of Microbiology
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    • v.47 no.2
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    • pp.158-162
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    • 2011
  • Amino acid sequence alignment shows that $\underline{P}$roteus $\underline{m}$irabilis $\underline{t}$ranscription $\underline{r}$egulator (PMTR) has cystein sequence homology at metal binding domain to CueR (copper resistance) protein, which conserves two cysteins (Cys 112 and Cys 120 in PMTR). Gel shift assay revealed that PMTR protein bound to promoter region of Escherichia coli copA (copper-translocating P-type ATPase) and Proteus mirabilis atpase (putative copper-translocating P-type ATPase) genes except that of E. coli zntA (zinc-translocating P-type ATPase) gene. DNase I protection experiment indicated that PMTR protein protected the region over -35 box and close to -10 box. DNase I hypersensitive bases were shown at C and A bases of labeled template strand and at G and C bases of labeled non-template strand of DNA. These hypersensitive bases were appeared in other metalloregulatory proteins of MerR family, which suggests protein-induced DNA bending.

Performance Analysis of New Working Solution for Absorption Refrigeration Machine using Treated Sewage (하수처리수이용 신용액 흡수식 냉동기의 성능해석)

  • 권오경;유선일;윤정인
    • Journal of Energy Engineering
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    • v.7 no.2
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    • pp.231-240
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    • 1998
  • The global environmental problems such as CFC, energy losses in heat recovery system as well as summer peak time power demands, the development of high efficiency absorption refrigeration systems is one of the most promising method in this problems. The absorption refrigeration system to utilize treated sewage is available for environmental protection and energy conservation. Simulation analysis on the double-effect absorption refrigeration cucles with parallel or series flow type has been performed. LiBr+LiI+LiCl+LiNO$_3$ solution was selected as the new working fluid. The main purpose of this study is evaluating the possibilities of effective utilization of treated sewage as a cooling water for the absorber and condenser. The other purpose of the present study is to determine the optimum designs and operating conditions based on the operating constraints and the coefficient of performance in the parallel or series flow type. In this study, we found out the characteristic of new working solution through the cycle simulation and compared LiBr solution to evaluate. The absorption refrigeration machine using the new working fluid was obtained better results COP rise and compactness of system by comparison with LiBr solution.

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A Response to Postural Response to Sine Curve Vestibular Electric Stimulation during Standing (기립자세동안 전정기관에 인가된 정현파 전류자극에 대한 자세균형 응답)

  • Lee, Ah-Reum;Yu, Mi;Kim, Jin-Ho;Kim, Dong-Wook;Kim, Jung-Ja
    • Journal of Biomedical Engineering Research
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    • v.31 no.3
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    • pp.210-216
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    • 2010
  • This study is vestibular electric stimulation applied between the mastoids during quiet standing elicits postural sway. The aim of this study was to characterize the postural sway response to continuous sinusoidal vestibular electric stimulation across various stimulus frequencies and amplitudes. Binaural bipolar sinusoidal vestibular electric stimulation was applied to the skin overlying the mastoid processes of 10 subjects while they stood on a force plate. The position of the center of pressure(COP) and signals at the feet are obtained on an force plate, while the head and whole body center of mass(COM) was measured with motion analysis system. The stimulus conditions included eight frequencies (1/64, 1/32, 1/16, 1/8, 1/4, 1/2, 1, and 2Hz) and six peak amplitudes (0.1, 0.25, 0.5, 0.7, 1 and 2mA). Each subject experienced one trial at each amplitude-frequency pair. The stimuli elicited sway in lateral plane in all subjects, as evidenced by changes in the stimulus frequency. Our results demonstrate that the vestibular system is sensitive to vestibular electric stimulation intensity changes and responds by altering the magnitude of the response accordingly.

Effect of Treadmill Walking Training using the Metronome on Gait Pattern (메트로놈을 이용한 트레드밀 보행훈련이 보행패턴에 미치는 영향)

  • Yoon, Won-Chan;Park, Sun-Wook
    • Journal of the Korean Society of Physical Medicine
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    • v.15 no.2
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    • pp.101-108
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    • 2020
  • PURPOSE: The purpose of this study was to investigate the effect of treadmill walking training using the metronome on the gait pattern. METHODS: A total of 33 healthy persons were studied consisting of 17 female and 16 male in the 20-30 age group. A gait analysis program was installed on a treadmill with a built - in gait analysis sensor and laptop. After 9 minutes of treadmill walking, gait analysis was performed for 1 minute. The mean values of the differences in the step length, angle of COP, separation line standard deviation and step force of the lower legs affecting walking symmetry were calculated for treadmill walking and treadmill walking using the metronome. The Shapiro-Wilk test was used to test the normality of the collected data and a paired t-test was performed to analyze the difference in walking before and after using the metronome. RESULTS: As a result of the analysis, the mean of difference between the measured values of the bilateral lower extremity for step length, angle of COP, separation line standard deviation and step force were statistically significant before and after treadmill walking using the metronome. CONCLUSION: Therefore, the treadmill walking training using the metronome is effective in decreasing the difference in the foot width, gait angle, gait distribution, and foot pressure. Because of this, the treadmill walking training using the metronome has a significant effect on walking symmetry among the elements for correct walking, which is a means for enabling efficient and continuous walking.

Effects of Various Sensory Stimulation on Surface Area and Velocity of Center of Pressure During One Leg Standing in Healthy Adults (건강인의 한발 서기 시 다양한 감각 자극이 압력 중심점 이동 면적과 속도에 미치는 영향)

  • Kim, Ga-hyun;Tak, Ji-yeon;Lim, Hak-hyun;Jeong, Hee-seon;Woo, Young-keun
    • Physical Therapy Korea
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    • v.22 no.3
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    • pp.41-49
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    • 2015
  • This study aimed to evaluate the surface area and velocity of center of pressure (COP) during one leg standing by stimulating the sensory system in normal adults. Thirty subjects were enrolled in this study. Subjects were asked to stand on one leg during testing conditions. Testing conditions included 6 different sensory stimulations as follows: eyes opened, eyes closed, eyes opened with vibrator, eyes opened with head-mounted display (HMD), eyes opened with vibrator and HMD, and eyes closed with vibrator. During each testing condition, the surface area and velocity of center of pressure were measured. There were significant differences in the mean surface area and the mean velocity of COP between the "eyes opened" condition and the other five testing conditions (p<.05). However, in the comparison between the "eyes closed" and "eyes opened with HMD" conditions, there were no significant differences in the tested parameters. This study shows that closing eyes or keeping eyes opened while using HMD to experience virtual reality has the same effect on one leg standing balance. This finding should be considered in the evaluation or intervention of balance, especially one leg standing balance and balance while standing with a small base of support.

Effect of Hip Joint Mobilization on Hip Mobility, Balance and Gait With Stroke Patients (고관절 관절가동기법이 뇌졸중 환자의 고관절 가동성, 균형과 보행능력에 미치는 효과)

  • Kim, Young-Hoon;Jang, Hyun-Jeong;Kim, Suhn-Yeop
    • Physical Therapy Korea
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    • v.21 no.2
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    • pp.8-17
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    • 2014
  • The purpose of this study was to examine the effects of hip joint mobilization (HJM) on walking ability, balance ability, and the joint range of motion in stroke patients to minimize the problems of the musculoskeletal system in patients with central nervous system diseases. All volunteers were randomly assigned to the HJM group ($n_1=14$) and the general neurodevelopment therapy (NDT) group ($n_2=16$). The HJM procedure involved applying Maitland mobilization techniques (distraction, lateral gliding, inferior gliding, and anterior gliding) by grade 3 to both hip joint. The mobilization process included mobilization and NDT for 15 min/day, 3 days a week for 4 weeks. The outcome measures were evaluated, including the hip joint passive range of motion (ROM) test and femur head anterior glide test (FHAG) using prone figure four test, dynamic and static balance abilities [timed up and go (TUG) test and center of pressure (COP) analysis], and walking ability [10-meter walking test (10MWT) and 6-min walking test (6MWT)]. Both the groups showed significant post-training differences in the hip joint ROM (FHAG and degree of hip extension) and 10MWT. The post-training improvements in the TUG test were significantly greater in patients of the HJM group than in the NDT group; however, there were no post-training improvements in COP in both groups. Patients in the HJM group showed post-training improvement in the 6MWT; however, statistically significant differences were not observed. Patients in the NDT group showed post-training improvements in the 6MWT. These results suggest that HJM improves hip joint ROM, dynamic balance ability, and walking speed in stroke patients. However, further studies are required to evaluate the long-term therapeutic efficacy of HJM in stroke patients.

Operating characteristics of 3RT heat pumps

  • Moon, Chang-Uk;Choi, Kwang-Hwan;Yoon, Jung-In;Jeon, Min-Ju;Heo, Seong-Kwan;Sung, Yo-Han;Park, Sung-Hyeon;Lee, Jin-Kook;Son, Chang-Hyo
    • Journal of Advanced Marine Engineering and Technology
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    • v.41 no.2
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    • pp.140-145
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    • 2017
  • Newly designed vapor-injection heat pumps have been proposed and analyzed in the present study. An economizer-type vapor-injection (V-I) system has been employed as the standard system because of its reliability and simple control method. The V-I system has a re-cooler and re-heater for cooling and heating, respectively. Solar panels have been installed in the V-I heat pump as well as in the re-heater in order to enhance heating capacity and performance. R410A has been employed as a working fluid and performance analysis has been conducted under various conditions. Results are summarized as follows: (1) The V-I system with the re-cooler yielded a marginally higher coefficient of performance (COP) than the conventional V-I refrigeration system. (2) By increasing the re-cooler cooling capacity, enhanced system performance as compared to the conventional V-I system was observed. (3) The re-heater negatively affected the system performance; hence, the V-I heat pump with the re-heater yielded a lower COP than that of the conventional V-I heat pump used for heating. (4) Although the solar panels increased the system performance, this increase could not offset performance degradation by the re-heater.

Studies on the Steady State and Dynamic Characteristics of a Carbon Dioxide Air-Conditioning System for Vehicles (자동차용 이산화탄소 냉방 시스템의 정상상태 및 동적 특성에 관한 연구)

  • Park, Min-Su;Kim, Sung-Chul;Kim, Dal-Won;Kim, Min-Soo
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.31 no.6 s.261
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    • pp.531-538
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    • 2007
  • In this study, an air conditioning system using carbon dioxide as a refrigerant was developed for automotive cabin cooling. Experiments have been carried out to examine the steady state and dynamic characteristics of this system. The system consists of a compressor, a gas cooler, an evaporator, an expansion device, an internal heat exchanger and an accumulator. The compressor is a variable displacement type, driven by the electric motor, and the gas cooler and the evaporator are aluminum extruded heat exchangers of micro channel type. The $CO_2-refrigerant$ charge, the compressor speed, the air inlet temperature of the gas cooler, the air inlet temperature and the air flow rate of the evaporator and the cooling load are varied and the performance of the system is experimentally investigated. As the compressor speed increased, cooling capacity increased, but the coefficient of performance was deteriorated. As the cabin air temperature or the air flow rate to the cabin was set high, both the cooling capacity and the COP increased. In the cool down experiment with 1.0 or 2.0 kW of heat load, the dynamic characteristics of the air-conditioning system were investigated. For a given capacity of compressor, cool down speed was monitored, and the temperature change was acceptable fur low heat load condition.

Analysis of Sloping Ground When Lifting with Force Platform (힘판을 이용한 들기 작업시의 경사면 분석)

  • 서승록;김종석
    • Journal of Korea Society of Industrial Information Systems
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    • v.5 no.1
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    • pp.77-86
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    • 2000
  • Even manual materials handling tasks(MMHT) is decreasing by adopt of automatic manufacturing system & transportation supporting machine because of increase of productivity, wage lack of labor, safety, in fact working at inclined & complicated slope such as farm, orchard, harbor loading & unloading, logging place and mining place can't be substituted by machine perfectly. So, workers should do MMHT at this place by themselves, lifting on slope can cause much of hazard, include falling. Keeping balance net to slip can be a reason of low back pain(LBP) by overloaded musculoskeletal system but, there's no enough study about lift on slope. Therefore, In this study, we assessed and analyzed change of center of pressure(COP) when lifting on slope by force platform. The result showed that the length lengthen as increasing angle of slope. Especially, the length extremely increased over 15°. Through These basic result, present proper angle boundary, prevent industrial accidents and give proper data not only lifting but also pushing and pulling on slope someday.

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The effect of hip abductor fatigue on static balance and gait parameters

  • Hwang, Wonjeong;Jang, Jun Ha;Huh, Minjin;Kim, Yeon Ju;Kim, Sang Won;Hong, In Ui;Lee, Mi Young
    • Physical Therapy Rehabilitation Science
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    • v.5 no.1
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    • pp.34-39
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    • 2016
  • Objective: Hip abductors play a role in providing stability and movement to the lower limbs. The purpose of this study was to examine the effects of hip abductor fatigue on static balance and gait in the general population. Design: One group pre-test post-test design. Methods: Thirteen university students in their twenties volunteered for the study and had underwent a functional assessment. To induce fatigue, the subjects were instructed to raise their dominant lower extremity up against a load of 50% of 1 repetition maximum while producing hip abduction in a side-lying position. Subjects were instructed to maintain an abduction speed of 30 repetitions per minute to induce fatigue. Muscle fatigue was considered to be established when subjects were unable to perform hip abduction three consecutive times along with the metronome. A post-test of balance and gait was performed immediately in order to prevent fatigue recovery. The center of pressure (COP) distance area was measured using the Zebris FDM-S Multifunction Force measuring plate. Gait performance was analyzed using the GAITRite. Results: The COP distance was increased after fatigue was induced. There was a significant increase in the standard deviation of the medio-lateral and antero-posteror distance (p<0.05). Although there was no significant difference in gait parameters, there was a significant decrease in single support time after fatigue was induced (p<0.05). Conclusions: There was an increase in static balance instability and a significant decrease in single support time during gait due to hip abductor muscle fatigue.