• Journal of the Korea Institute of Information Security & Cryptology
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• v.22 no.6
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• pp.1271-1282
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• 2012

Recently, security incidents occur continuously, resulting in the leakages of a large amount of the company's confidential and private information. For these reasons, the security technologies such as the authentication and the access control in order to prevent the information leakage are attracting attention. In particular, location-based authentication that utilizes the user's current location information which is used an authentication factor. And it provides more powerful authentication by controlling the users who attempt to access and blocks internal information leakage path. However, location information must be handled safely since it is the personal information. The location based authentication scheme proposed in this paper enhances the stability of the process location information compared with existing relevant location-based authentication protocol. Also it strengthens the end-user authentication by using one-time password. In addition, the proposed scheme provides authentication to prevent information leakage and employs the concept of the user's physical access control. Resultingly, the proposed scheme can provide higher security than the previous studies, while guarantee to low communication cost.

• Human Ecology Research
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• v.59 no.1
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• pp.127-141
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• 2021

This study evaluates the financial status of Korean households using Household Financial Composite Index (HFCI) proposed in the preceding study. We analyzed 1,566 households with four persons aged 30-59 using raw data from the Korea Labor Panel Survey in 2016. The analysis results are as follows. First, HFCI was found to be 57.0 out of 100. Growth Index as one of three subindices was 11.1, which was significantly lower with 65.0 points for Status Index and 61.1 points for the Stability Index. Second, for households with male household owners, the overall financial score was 57.0, while that with female owners was almost similar with 57.2. HFCI was similar for the owner's age groups, but for Status Index, 58.5 for 30s, compared with 66.1 for 40s and 67.1 for 50s. The higher the education level of household owners, the better HFCI, with 53.2 high school graduates and 64.8 graduate graduates, showing a high gap of 11.6 points. HFCI for households living in owned housing was highest at 60.0, while that for rented housing was 40.7. Third, after controlling other effects, it was found that HFCI differed according to the level of education and ownership of housing living. Householder's gender was not found as a significant factor on HFCI. Status Index The 40s and 50s was higher than those in their 30s. Fourth, households were divided into three groups based on HFCI, named as risk, average and secure groups. HFCI for the risk group was 26.8, which was lower than 78.6 for the secure group, with a Status Index of 19.3. Households in their 50s and graduate school graduates were significantly included in the list of secure groups than others.

• Korea Journal of Hospital Management
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• v.26 no.1
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• pp.42-54
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• 2021

The purpose of this study is to analyze that ICT-based primary health care affects clinical changes of participants in the primary care chronic disease management pilot project using ICT medical care. Customized health information data, provided by National Health Insurance Service, was used for the analysis. The study targeted a total of 676 people that participated in primary care chronic disease management pilot project using ICT medical care from 2017 to 2018. Hierarchical regression was used to test three model. First, there were many subjects who used face-to-face consultation and non-face-to-face consultation(messaging), but less than half of patients using non-face-to-face consultation(telephone). Second, after participating in the pilot project, the fasting blood sugar level decreased. Third, the clinical condition of the subjects appeared to be an important factor in controlling blood sugar levels. Finally, patients using the non-face-to-face consultation(messaging) had reduced blood sugar levels after participating in the project. This results imply that non-face-to-face consultation is effective in reducing fasting blood sugar level with hospital intervention, and there are effects of the primary care chronic disease management project using ICT.

• Journal of the Korea Society of Computer and Information
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• v.27 no.1
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• pp.51-59
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• 2022

As the weapon system's dependence on software functions increased, software became a key factor in controlling the weapon system. In addition, as software development becomes more important domestically and internationally, software verification becomes an issue. The recent defense market has recognized this point and is demanding a plan for weapon system software maintenance. In this paper, we propose a weapon system software maintenance plan using Automatic Test Equipment. The specific method is to use a simulator to check the software function and identify failure cases. This is an effective way for developers to reduce the Total Corrective Maintenance Time(TCM) of the weapon system by reducing the time it takes to identify failure cases. It has been proven that the proposed Automatic Test Equipment can achieve software maintenance and excellent Maintainability and Operational Availability compared to the existing ones.

• Journal of Microbiology and Biotechnology
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• v.32 no.2
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• pp.220-227
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• 2022

The spread of antibiotic-resistant strains of Staphylococcus aureus, a gram-positive opportunistic pathogen, has increased due to the frequent use of antibiotics. Inhibition of the quorum-sensing systems of biofilm-producing strains using plant extracts represents an efficient approach for controlling infections. Torilis japonica is a medicinal herb showing various bioactivities; however, no studies have reported the anti-biofilm effects of T. japonica extracts against drug-resistant S. aureus. In this study, we evaluated the inhibitory effects of T. japonica ethanol extract (TJE) on biofilm production in methicillin-sensitive S. aureus (MSSA) KCTC 1927, methicillin-resistant S. aureus (MRSA) KCCM 40510, and MRSA KCCM 40511. Biofilm assays showed that TJE could inhibit biofilm formation in all strains. Furthermore, the hemolysis of sheep blood was found to be reduced when the strains were treated with TJE. The mRNA expression of agrA, sarA, icaA, hla, and RNAIII was evaluated using reverse transcription-polymerase chain reaction to determine the effect of TJE on the regulation of genes encoding quorum sensing-related virulence factors in MSSA and MRSA. The expression of hla reduced in a concentration-dependent manner upon treatment with TJE. Moreover, the expression levels of other genes were significantly reduced compared to those in the control group. In conclusion, TJE can suppress biofilm formation and virulence factor-related gene expression in MSSA and MRSA strains. The extract may therefore be used to develop treatments for infections caused by antibiotic-resistant S. aureus.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.16 no.2
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• pp.47-54
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• 2021

Objectives This review was conducted to study use of Aconitum herbal medicine for pain control in musculoskeletal disease. Methods Musculoskeletal disease is a major factor of social cost increase and physical disability. Various drugs, surgery and imaging are being overused regardlessly. Aconitum herbal plants are one of the most toxic Korean traditional herbs. However, they could be utilized effectively on patients with appropriate processing and decocting time. We searched Korean medicine literature to see various features of aconitum herbal plants and tried to find the utilization of the plants in effective way for pain control in musculoskeletal disease. Results Aconitum herbal plants needs to be used carefully because of intoxication which could lead to severe damage to human body. Processing of these toxic plants could minimize the harm and raise the benefits, such as relieving various types of pain and positive inotropic action. Further studies with clearer evidence and discovering aftereffects of processing in more details are needed. Conclusions Aconitum herbal plants could dedicate to controlling pain in musculoskeletal disease with various forms and appropriate processing.

• Journal of Gastric Cancer
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• v.22 no.1
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• pp.56-66
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• 2022

Purpose: Nutritional problems after gastrectomy affect continuation of postoperative chemotherapy. There have been no studies limited to total gastrectomy, which is particularly prone to nutritional problems. In this study, we aimed to investigate the factors that predict the continuation of postoperative chemotherapy. Materials and Methods: We included 101 patients who underwent curative total gastrectomy and postoperative chemotherapy at Hiroshima Memorial Hospital. The effects of 37 factors, including perioperative inflammatory, nutritional, and tumor status, on the persistence of postoperative chemotherapy were analyzed. Results: In univariate analysis of preoperative factors, age, carbohydrate antigen 19-9, platelet-to-neutrophil ratio, Onodera's prognostic nutritional index (PNI), controlling nutritional status score, and nutritional risk screening (NRS-2002) score were significantly associated with the duration of postoperative chemotherapy. In multivariate analysis of preoperative factors, age (≥74 years) was an independent factor for a shorter duration of postoperative chemotherapy (hazard ratio [HR], 5.24; 95% confidence interval [CI], 2.19-12.96; P<0.01). In univariate analysis of factors before postoperative chemotherapy, intraoperative blood loss, perioperative weight loss rate, postoperative performance status, PNI, albumin-to-bilirubin index, and NRS-2002 score were significantly associated with the duration of postoperative chemotherapy. In multivariate analysis of factors before postoperative therapy, age (≥74 years) (HR, 5.75; 95% CI, 1.90-19.49; P<0.01) and PNI (<39) (HR, 3.29; 95% CI, 1.26-8.56; P=0.02) were independent factors for a shorter duration of postoperative chemotherapy. Conclusions: Age and PNI are useful predictors of postoperative chemotherapy intolerance after total gastrectomy and may determine the treatment strategy and timing of chemotherapy initiation.

• The Journal of the Korea Contents Association
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• v.22 no.10
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• pp.271-278
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• 2022

MyData service integrates and manages user's personal data such as finance, credit, etc, and is expected to provide useful information to the user as personal data in various fields are gradually integrated. Discovering factors that affect the intention to use of MyData service is a very important topic for understanding that service. To this end, in this study, the attributes of the MyData service were derived, and the derived service attributes were grouped together by using factor analysis. As a result, we found four factors such as "convenience", "usefulness", "security", and "control". After that, we established our research model to analyze the causal relationship between these four factors and the intention to use of MyData service. According to the analysis results, among the factors of the MyData service attribute, "convenience", "usefulness", and "control" had a significant effect, and "security" did not have a significant effect. In particular, it was confirmed that "control" had the greatest influence on the intention to use. This study suggests that MyData service provider need to make users recognize they are controlling their data and develop services that provide various benefits to users.

• Biomolecules & Therapeutics
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• v.30 no.6
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• pp.540-545
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• 2022

Betulin is a triterpenoid natural product contained in several medicinal plants including Betulae Cortex. These medicinal plants have been used for controlling diverse inflammatory diseases in folk medicine and betulin showed anti-inflammatory, antioxidative, and anticancer activities. In this study, we tried to examine whether betulin exerts a regulative effect on the gene expression of MUC5AC mucin under the status simulating a pulmonary inflammation, in human airway epithelial cells. Confluent NCI-H292 cells were pretreated with betulin for 30 min and then stimulated with phorbol 12-myristate 13-acetate (PMA) for 24 h or the indicated periods. The MUC5AC mucin mRNA expression and mucin glycoprotein production were measured by reverse transcription - polymerase chain reaction (RT-PCR) and enzyme-linked immunosorbent assay (ELISA), respectively. To elucidate the action mechanism of betulin, effect of betulin on PMA-induced nuclear factor kappa B (NF-kB) signaling pathway was also investigated by western blot analysis. The results were as follows: 1) Betulin significantly suppressed the production of MUC5AC mucin glycoprotein and down-regulated MUC5AC mRNA expression induced by PMA in NCI-H292 cells. 2) Betulin inhibited NF-κB activation stimulated by PMA. Suppression of inhibitory kappa B kinase (IKK) by betulin led to the inhibition of the phosphorylation and degradation of inhibitory kappa B alpha (IκBα), and the nuclear translocation of NF-κB p65. This, in turn, led to the down-regulation of MUC5AC glycoprotein production in NCI-H292 cells. These results suggest betulin inhibits the gene expression of mucin through regulation of NF-kB signaling pathway, in human airway epithelial cells.

• Korea Journal of Hospital Management
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• v.27 no.3
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• pp.26-38
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• 2022

Purposes: We analyzed the profitability determinants of regional public hospitals during the entire period between 2010 and 2020 and the period before and after COVID-19. We intended to provide fundamental data for developing publicness evaluation index and task of establishing and expanding regional public hospitals. Methodology: The financial and non-financial information of the regional public hospitals were used as the main analysis data; The financial data was established by the Center for Public Healthcare Policy of National Medical Center, and the non-financial data by the Health Insurance Review and Assessment Service. T-test and regression analysis were used. Findings: The results can be summarized in two. First, the main determinants of profitability of the regional public hospitals were appeared to be the total asset turnover rate and the labor cost rate. Second, during the COVID-19 pandemic in the regional public hospitals, the number of sickbeds, the number of isolation rooms, the total asset turnover rate and the labor cost rate appeared to be the factor worsening the profitability. Practical Implication: The results of this study suggests that the management of the regional public hospitals is not aiming for the profit making, but it performs the functions as the community healthcare safety net such as controlling infectious diseases.