• Journal of Powder Materials
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• v.28 no.6
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• pp.518-526
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• 2021

This review summarizes the recent progress in iron-oxide-based heat generators. Cancer treatment using magnetic nanoparticles as a heat generator, termed magnetic fluid hyperthermia, is a promising noninvasive approach that has gained significant interest. Most previous studies on improving the hyperthermia effect have focused on the construction of dopant-containing iron oxides. However, their applications in a clinical application can be limited due to extra dopants, and pure iron oxide is the only inorganic material approved by the Food and Drug Administration (FDA). Several factors that influence the heat generation capability of iron-oxide-based nanoparticles are summarized by reviewing recent studies on hyperthermia agents. Thus, our paper will provide the guideline for developing pure iron oxide-based heat generators with high heat dissipation capabilities.

• International Journal of Concrete Structures and Materials
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• v.2 no.2
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• pp.137-143
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• 2008

In recent years, much research work has been performed on durability design and long-term performance of concrete structures in marine environments. In particular, the development of new procedures for probability-based durability design has been shown to provide a more realistic basis for the analysis. This approach has been successfully applied to several new concrete structures, where requirements for a more controlled durability and service life have been specified. For reinforced concrete structures in a marine environment, it is commonly assumed that the dominant degradation mechanism is the corrosion of the reinforcement due to the presence of chlorides. The design approach is based on the verification of durability limit states, examples of which are: depassivation of reinforcement, cracking and spalling due to corrosion, and collapse due to cross section loss of reinforcement. With this design approach the probability of failure can be determined as a function of time. In the present paper, a probability-based durability performance analysis is used in order to demonstrate the importance of the durability design approach of concrete structures in marine environments. In addition, the sensitivity of the various durability parameters affecting and controlling the durability of concrete structures in a marine environment is studied. Results show that the potential of this approach to assist durability design decisions making process is great. Based the crucial information generated, it is possible to prolong the service life of structures while simultaneously optimizing the final design solution.

• Structural Engineering and Mechanics
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• v.78 no.1
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• pp.87-102
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• 2021

Long span cross-rope suspension structure is an innovative structural system evolved from typical Cross-Rope Suspension (CRS) guyed tower, a type of supporting system with short span suspension cable supporting overhead power transmission lines. In mountainous areas, the span length of suspension cable was designed to be extended to hundreds or over one thousand meters, which is applicable for crossing deep valleys. Vortex Induced Vibration (VIV) of overhead power transmission lines was considered to be one of the major factors of its fatigue and service life. In this paper, VIV and its controlling by Stockbridge damper for long span CRS was discussed. Firstly, energy balance method and finite element method for assessing VIV of CRS were presented. An approach of establishing FE model of long span CRS structure with dampers was introduced. The effect of Stockbridge damper for overall vibration of CRS was compared in both theoretical and numerical approaches. Results indicated that vibration characteristics of conductor in long span CRS compared with traditional tower-line system. Secondly, analysis on long span CRS including Stockbridge damper showed additional dampers installed were essential for controlling maximum dynamic bending stresses of conductors at both ends. Moreover, factors, including configuration and mass of Stockbridge damper, span length of suspension cable and conductor and number of spans of conductor, were assessed for further discussion on VIV controlling of long span CRS.

• Nuclear Engineering and Technology
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• v.55 no.9
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• pp.3277-3290
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• 2023

Nuclear power plant (NPP) operations with multiple objectives and devices are still performed manually by operators despite the potential for human error. These operations could be automated to reduce the burden on operators; however, classical approaches may not be suitable for these multi-objective tasks. An alternative approach is deep reinforcement learning (DRL), which has been successful in automating various complex tasks and has been applied in automation of certain operations in NPPs. But despite the recent progress, previous studies using DRL for NPP operations have limitations to handle complex multi-objective operations with multiple devices efficiently. This study proposes a novel DRL-based approach that addresses these limitations by employing a continuous action space and straightforward binary rewards supported by the adoption of a soft actor-critic and hindsight experience replay. The feasibility of the proposed approach was evaluated for controlling the pressure and volume of the reactor coolant while heating the coolant during NPP startup. The results show that the proposed approach can train the agent with a proper strategy for effectively achieving multiple objectives through the control of multiple devices. Moreover, hands-on testing results demonstrate that the trained agent is capable of handling untrained objectives, such as cooldown, with substantial success.

• Biotechnology and Bioprocess Engineering:BBE
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• v.7 no.5
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• pp.237-251
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• 2002

The recent progress on metabolic systems engineering was reviewed based on our recent research results in terms of (1) metabolic signal flow diagram approach, (2) metabolic flux analysis (MFA) in particular with intracellular isotopomer distribution using NMR and/or GC-MS, (3) synthesis and optimization of metabolic flux distribution (MFD), (4) modification of MFD by gene manipulation and by controlling culture environment, (5) metabolic control analysis (MCA), (6) design of metabolic regulation structure, and (7) identification of unknown pathways with isotope tracing by NMR. The main characteristics of metabolic engineering is to treat metabolism as a network or entirety instead of individual reactions. The applications were made for poly-3-hydroxybutyrate (PHB) production using Ralstonia eutropha and recombinant Escherichia coli, lactate production by recombinant Saccharomyces cerevisiae, pyruvate production by vitamin auxotrophic yeast Toluropsis glabrata, lysine production using Corynebacterium glutamicum, and energetic analysis of photosynthesic microorganisms such as Cyanobateria. The characteristics of each approach were reviewed with their applications. The approach based on isotope labeling experiments gives reliable and quantitative results for metabolic flux analysis. It should be recognized that the next stage should be toward the investigation of metabolic flux analysis with gene and protein expressions to uncover the metabolic regulation in relation to genetic modification and/ or the change in the culture condition.

• Journal of applied mathematics & informatics
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• v.7 no.2
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• pp.409-438
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• 2000

In this paper we develop a new procedure to control stepsize for Runge- Kutta methods applied to both ordinary differential equations and semi-explicit index 1 differential-algebraic equation In contrast to the standard approach, the error control mechanism presented here is based on monitoring and controlling both the local and global errors of Runge- Kutta formulas. As a result, Runge-Kutta methods with the local-global stepsize control solve differential of differential-algebraic equations with any prescribe accuracy (up to round-off errors)

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2001.10a
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• pp.336-340
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• 2001

Theoretical efforts were taken to investigate an optimum heat treatment process in martensitic stainlesssteel. The approach is based on the combination of the interpolation and extrapolation method of a standard heat treatment technology with the principle of quenching and tempering temperature difference. The relationship of macroscopic structure and fracture toughness and ductility as well as the Hardness and strength has been focused to induce a simple rule to apply with feasibility. As a result it was found that the grain size influences to the fracture toughness and ductility significantly.

• Proceedings of the KAIS Fall Conference
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• 2007.05a
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• pp.249-252
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• 2007

This study shows possibility of Matlab and LabVIEW integration for controlling of robot's manipulator. Examined approach can be used for control of complex system with intelligent control capability. Instance of Robotic System controller is described in details. Structure of control system is divided into three parts Virtual Instrument of LabVIEW, MatLab Script for solving and Matlab Simulink model for visualizing, which are explained separately. In addition, used neglects are explained and founded.

• 전기의세계
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• v.29 no.12
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• pp.791-797
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• 1980

This paper is concerned with the study of improving the faults of phase control scheme and suggesting a new approach to the control of load circuit with AC source. AC current control can restrict the magnitude of current within the given upper and lower current and make current continuous during every cycle. Also the harmonic contents of current can be greatly reduced using this control scheme. Analog computer and digital computer simulations reveal that the current control scheme is superior to the phase control scheme in controlling the power supply to the load R-L. Experimintal results demonstrate the feasibility and verify the operation of current controlled system.

• 한국정보디스플레이학회:학술대회논문집
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• 2008.10a
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• pp.1564-1567
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• 2008

We demonstrate here a self-aligned printing approach that allows downscaling of printed organic thin-film transistors to channel lengths of 100 - 400 nm. A perfected down-scaled polymer transistors (L= 200 nm) showing high transition frequency over 1.5 Mhz were realized with thin polymer dielectrics, controlling contact resistance, and minimizing overlap capacitance via self-aligned gate configuration.