• Title/Summary/Keyword: control period

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Study on a 4-Week Recovery Test of Sweet Bee Venom after a 13-Week, Repeated, Intramuscular Dose Toxicity Test in Sprague-Dawley Rats

  • Kang, Hyunmin;Lim, Chungsan;Lee, Seungbae;Kim, Byoungwoo;Kwon, Kirok;Lee, Kwangho
    • Journal of Pharmacopuncture
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    • v.17 no.2
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    • pp.18-26
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    • 2014
  • Objectives: This study was performed to check for reversibility in the changes induced by a 13-week, repeated, dose toxicity test of Sweet Bee Venom (SBV) in Sprague-Dawley (SD) rats. Methods: Fifteen male and 15 female SD rats were treated with 0.28 mg/kg of SBV (high-dosage group) and the same numbers of male and female SD rats were treated with 0.2 mL/kg of normal saline (control group) for 13 weeks. We selected five male and five female SD rats from the high-dosage group and the same numbers of male and female SD rats from the control group, and we observed these rats for four weeks. We conducted body-weight measurements, ophthalmic examinations, urinalyses and hematology, biochemistry, histology tests. Results: (1) Hyperemia and movement disorder were observed in the 13-week, repeated, dose toxicity test, but these symptoms were not observed during the recovery period. (2) The rats in the high-dose group showed no significant changes in weight compared to the control group. (3) No significant differences in the ophthalmic parameters, urine analyses, complete blood cell counts (CBCs), and biochemistry were observed among the recovery groups. (4) No changes in organ weights were observed during the recovery period. (5) Histological examination of the thigh muscle indicated cell infiltration, inflammation, degeneration, necrosis of muscle fiber, and fibrosis during the treatment period, but these changes were not observed during the recovery period. The fatty liver change that was observed during the toxicity test was not observed during the recovery period. No other organ abnormalities were observed. Conclusion: The changes that occurred during the 13-week, repeated, dose toxicity test are reversible, and SBV can be safely used as a treatment modality.

A Dynamic Signalling Period Allocation Algorithm in Wireless ATM MAC Protocols (무선 ATM MAC 프로토콜에서 동적 신호 주기 할당 알고리즘)

  • 강상욱;신요안;최승철
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.24 no.6B
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    • pp.1004-1014
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    • 1999
  • MAC protocols in wireless ATM has to increase and maintain the system throughput performance. To achieve these purposes, this paper proposes a dynamic control algorithm called DSPA (Dynamic Signalling Period Allocation) for wireless ATM MAC protocol. The proposed DSPA algorithm consists of the following three algorithms. First, a control slot generation algorithm which generates the control slots by utilizing static and dynamic parameters from the terminals, is proposed. Second, a dynamic signalling period allocation algorithm is proposed for a base station to dynamically determine each signalling period according to current terminal states, and thus allocates the optimal signalling periods. Finally, a dynamic slot allocation algorithm is proposed to dynamically determine priorities of the terminals whenever a slot is allocated. Simulation results indicates that DSPA algorithm decreases average packet delay of the terminals by dynamic allocation of signal periods based on the system utilization, and thus increases the limitation of allowable loads that quarantee quality of services. Also the proposed algorithm is shown to maintain stable throughput even in the case of traffic variations.

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The Effect of a Childcare Education for First-time Mothers on Newborn Care Behavior and Confidence in Maternal Role (초산모를 위한 육아 교육이 어머니의 신생아 양육행동과 어머니 역할에 대한 자신감에 미치는 효과)

  • Lee, Ja-Hyung
    • Women's Health Nursing
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    • v.4 no.3
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    • pp.322-331
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    • 1998
  • The postpartum is a period of transition to motherhood where a childless woman transforms into a woman with children. Parents, especially mothers must perform an essential role of implementing instrumental and emotional care behaviors on part of the helpless, dependent, and immature infant. First-time mothers, however, suddenly face the responsibility of round the clock duty without neither parenting training during pregnancy, nor a time to gradually adapt to growing responsibilities after birth, with confusion and frustration as a result. Thus, after providing first-time mothers with childcare education as maternal role preparation, this study will try to examine its effects on childcare behaviors and confidence in maternal role during the early postpartum period. This quasi-experimental study using a nonequivalent control group non-synchronized design, was carried out from March 1995 to May 1996 to verify the effects of a childcare education program with first-time mothers who had vaginal delivery in Ewha University Hospital, Seoul, Korea, and collected data from 60 subjects who consented to the study. The education was given in the early postpartum period(48-72 hours after delivery) and to measure its effects, a posttest was done 4 weeks later with the results analyzed by SPSS shown in the following : 1. The childcare behavior score of the experimental group that had received the newborn care education was higher than the control group(t=3.5, P=.001). 2. The control group and the experimental group which had received the education showed no difference in degree of confidence in maternal role. 3. The higher the childcare behavior score, the higher the degree of confidence in maternal role was among the subjects(r=.56, P=.001). The preceding results are significant in that childcare practices can be promoted by providing child-care education to first-time mothers in the early postpartum period. Thus, this education can be used as a nursing intervention strategy in the early postpartum period.

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Alveolar restoration following rapid maxillary expansion with and without corticotomy: A microcomputed tomography study in sheep

  • Le, My Huy Thuc;Hayaty, Abu Kasim Noor;Zaini, Zuraiza Mohamad;Dom, Sulaiman Md;Ibrahim, Norliza;Radzi, Zamri Bin
    • The korean journal of orthodontics
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    • v.49 no.4
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    • pp.235-245
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    • 2019
  • Objective: This study examined bone microstructure restoration after rapid maxillary expansion (RME) with and without corticotomy over multiple retention periods. Methods: Eighteen male Dorper sheep were randomly distributed into three groups (n = 6 each group): group 1, RME with corticotomy on the buccal and palatal sides; group 2, conventional RME treatment; and group 3, no treatment. Post-RME, trabecular bone microstructure and new bone formation were evaluated by using microcomputed tomography (microCT) and histomorphometry after a 4- or 12-week retention period. Intergroup differences in bone quality and bone remodeling were analyzed by using two-way analysis of variance with Bonferroni post-hoc test. Results: The bone volume fraction (bone volume [BV]/total volume [TV]) values relative to the control in groups 1 and 2 were 54.40% to 69.88% after the 4-week retention period and returned to approximately 80% after the 12-week retention period. The pooled BV/TV values of the banded teeth in groups 1 and 2 were significantly lower than those of the control after the 4-week retention period (p < 0.05). However, after the 12-week retention period, the pooled BV/TV values in group 2 were significantly lower than those in groups 1 and 3 (p < 0.05). Histomorphological analysis showed that the new bone formation area in group 1 was approximately two to three times of those in group 2 and control. Conclusions: Corticotomy significantly enhanced the restoration of bone quality after the retention periods for banded teeth. This benefit might result from the increased new bone formation after corticotomy.

Impacts of Corruption Control on Economic Growth in Relationship with Stock Market and Trade Openness

  • PHAM, Van Thi Hong
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.12
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    • pp.73-84
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    • 2020
  • The study aims to investigate the dual effects of corruption control on economic growth in relationship with the stock market and trade openness in developing countries. The study used difference S-GMM method on the dynamic panel data model in the period (2002-2017) with data collected from the World Bank. The study discovers the dominant impacts of corruption control in the relationship with the stock market on economic growth. At the same time, the study also confirms the overwhelming impact of corruption control in the relationship between trade openness and economic growth in the developing countries. In addition, the study shows that inefficient stock markets in developing countries will not promote economic growth. Meanwhile, the long-standing credit market has a positive impact on economic growth. With the strong development of stock market and trade openness in the period (2002-2017), control on corruption in developing countries does not get better in time with the increase in demand. The findings of this study suggest a number of solutions to strengthen corruption control, leading to the increased efficiency on the stock market and as well as encouraging the positive effects of trade openness to contribute to promoting economic growth in developing countries.

Effect of $\alpha$-, ${\gamma}$-, $\delta$-Tocopherol on Fatty Acids Composition of Hamburger Patties during Frozen Storage ($\alpha$-, ${\gamma}$-, $\delta$-Tocopherol의 첨가가 동결 저장중 Hamburger Patty의 지방산 조성에 미치는 영향)

  • 박구부;성필남;송또준;김진성;박태선;이정일;김진형
    • Food Science of Animal Resources
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    • v.18 no.1
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    • pp.1-8
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    • 1998
  • This study was conducted to investigate the effects of $\alpha$-, ${\gamma}$-, $\delta$-Tocopherols on oxidative stability of lipid in hamburger patties during frozen storage. Hamburger patty samples were prepared with the addition of tocopherol by fat basis: control, treat 1 (control+0.02% $\alpha$-tocopherol), treat 2 (control+ 0.02% ${\gamma}$-tocopherol were cooked at 85$^{\circ}C$ for 3 minutes and the stored at -1$0^{\circ}C$ or 3$0^{\circ}C$). The fatty acids composition of the hamburger samples were analyzed during the storage periods (1, 20, 40, 60 and 80 days). there was no difference in the fatty acids composition among control and treatment groups in early storage time; however, content of unsaturated fatty acid was decreased in control group and slightly decreased or almost not changed in treatment groups as the storage period passed. No difference in the ratio of saturated fatty acid : unsaturated fatty acid (SFA : USFA) and saturated fatty acid : monounsaturated fatty acid : unsaturated fatty acid (SFA : MUFA : PUFA) between control and treatment groups at early storage time. However, SFA : USFA and SFA : MUFA : PUFA was decreased in control and slightly decreased or not changed in all treatment groups as the storage period passed.

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Study on the Control System Based on Results Measurement (업적기준 통제시스템에 관한 연구)

  • 정신작;손병기
    • The Journal of Fisheries Business Administration
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    • v.28 no.1
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    • pp.85-117
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    • 1997
  • This paper is focused on management control system. From a management control perspective, strategies should be viewed as useful, but not absolutely necessary, guides to the proper design of an MCS. When strategies are formulated more clearly, more control alternatives become feasible and it becomes easier to implement each form of management control effectively. The common and important category of controls are action controls, personnel and cultural controls, and results controls. Action controls involves ensuring that employees perform(or do not perform) certain actions that are known to be beneficial(or harmful) to the organization. Personnel and cultural controls take steps to ensure that employees will control each others' behaviors. Results controls involve rewarding individuals(and sometimes groups of individuals) for generating good outcomes or punishing them for poor outcomes. The results controls of ROI-type measure cause to make managers excessively short- term oriented, or myopic. When managers' orientations to the short - term become excessive -when the management are more concerned with short-term profit than entity value-the managers are said to be myopic. We car, solve myopic problem by introducing AR(abnormal return), near-perfect indicators of value creation. The results - control ideal would be to hold all employees accountable for the wealth they individually create(or destroy) for the owners of the entities in which they work. This ideal is approachable for top management of publicly traded corporations because for these organizations, the wealth created(returns to shareholders) can be measured directly for any period(such as a year, a quarter, or a month) as the measurement period pin(or minus) the change in the market value of the stock.

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A Study on The Dynamical Property of Input/output of Motion System for Machinery Control (기계 제어를 위한 모션시스템 입출력에 대한 동적 특성 연구)

  • Hyun, Sunghoon;Kim, Dongyon;Park, Janghwan
    • Journal of the Institute of Electronics and Information Engineers
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    • v.52 no.12
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    • pp.118-123
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    • 2015
  • The study of input and output characteristics in dynamic motion control is important indicator of the performance of mechanical equipment and is the factors to be considered during commissioning and maintenance of machinery or equipment, and project planning. The Analysis on dynamical characteristic of the input/output of the automation solution that used for motion control in machinery, is represented the control performance of device and including controller which connected at automation network by considering period of the frequency as applied load. This paper was constructed the simulator of B & R Powerlink to be widely used for motion control in the machine and showed the dynamic system characteristics by analysing the period.

Hydraulic Characteristics and Dynamic Behaviors of Floating Breakwater with Vertical Plates (연직판형 부소파제의 수리학적 특성과 동적거동)

  • SOHN Byung-Kyu;YANG Yong-Su;JEONG Seong-Jae;SHIN Jong-Keon;KIM Do-Sam
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.38 no.5
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    • pp.316-322
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    • 2005
  • In order to develop a floating breakwater, which can efficiently control long period waves, vertical plates are attached in pontoon. Wave control and dynamic behaviors of the newly developed vertical plates type are verified from numerical analysis and hydraulic experiment. As a result, for the wave control and energy dissipation, the newly developed vertical plates type is more efficient than the conventional pontoon type. For the floating body motion, the wave transmission, depending on incident wave period, is decreased at the natural frequency. Dimensionless drift distance has similar trend of the reflection rate of wave transformation near natural frequency except maximum and minimum values. Dimensionless maximum tension is 17 percent of the weight of floating breakwater in case of the conventional pontoon type and 18 percent or 14 percent in case of the newly developed vertical plates type. Thus, it is shown that the wave control is improved by the vertical plates type. In addition, by adjusting the interval of the front and back vertical plate, we would control proper wave control.

Deadbeat Control with a Repetitive Predictor for Three-Level Active Power Filters

  • He, Yingjie;Liu, Jinjun;Tang, Jian;Wang, Zhaoan;Zou, Yunping
    • Journal of Power Electronics
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    • v.11 no.4
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    • pp.583-590
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    • 2011
  • Three-level NPC inverters have been put into practical use for years especially in high voltage high power grids. This paper researches three-level active power filters (APFs). In this paper a mathematical model in the d-q coordinates is presented for 3-phase 3-wire NPC APFs. The deadbeat control scheme is obtained by using state equations. Canceling the delay of one sampling period and providing the predictive value of the harmonic current is a key problem of the deadbeat control. Based on this deadbeat control, the predictive output current value is obtained by the state observer. The delay of one sampling period is remedied in this digital control system by the state observer. The predictive harmonic command current value is obtained by the repetitive predictor synchronously. The repetitive predictor can achieve a better prediction of the harmonic current with the same sampling frequency, thus improving the overall performance of the system. The experiment results indicate that the steady-state accuracy and the dynamic response are both satisfying when the proposed control scheme is implemented.