• Title/Summary/Keyword: control data

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The Antioxidative Activity of Glutathione-Enriched Extract from Saccharomyces cerevisiae FF-8 in In Vitro Model System (In Vitro 과산화지질에 미치는 glutathione 고함유 효모 Saccharomyces cerevisiae FF-8의 항산화효과)

  • Lee Chi-Hyeoung;Cha Jae-Young;Jun Bang-Sil;Lee Ho-Jun;Lee Young-Chun;Cho Yong-Lark;Cho Young-Su
    • Journal of Life Science
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    • v.15 no.5 s.72
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    • pp.819-825
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    • 2005
  • The Antioxidative accvities of the cell free extracts containing high glutathione by Saccharomyces cerevisiae FF-8 were tested in vitro experimental models : DPPH method for radical scavenging activity, ferric TBA method and ferric thiocyanate method using linoleic acid and tissue microsome for lipid peroxidation inhibitions. The concentration of intercellular glutathione by cultivating S. cerevisiae FF-8 in the YM optimal medium obtained $204\mug/ml$, which was increased by 2.76-fold from $74\mug/ml$ in the YM basal medium. A comparition between the YM basal medium and the YM optimal medium on antioxidative substance produced by S. cerevisiae FF-8 was investigated. In DPPH ($\alpha, \alpha-diphenyl-\beta-picrylhydrazyl$) method, the electron donating activity of the glutathione produced by S. cerevisiae FF-8 cultured in the YM optimal medium was as high as that of BHT ($ 0.05\%w/v $). The antioxidative a.tivity was measured by inhibition against lipid peroxidation of rat tissues' microsomes. The results of anti-oxidant activity of the cell free extracts by S. rerevisiae FF-8 cultured in the YM optimal medium was shown in the following order . $ liver 60.98\% > kidney 56.43\% > heart 52.91\% > brain 52.13\% > testis 45.57\% > spleen 42.95\% $. In antioxidative activities determined by ferric thiocyanate method and TBA methods against lipid peroxidation, the lipid peroxidation in the control mixture increased more rapidly than the typical peroxidation curve of linoleic acid from one day. The antioxidative activity of the cell free extracts by cultivating S. cerevisine FF-8 in the YM optimal medium were higher than that of the YM basal medium. These data indicate that the cell free extracts containing a high intercellular glutathione of S. cerevisiae FF-8 cultured in YM optimal medium showed strong antioxidative capacities by DPPH radical scavenging activity and ferric thiocyanate and TBARS measurements.

Effects of Acanthopanax Senticosus Leaves Supplementation on Performance, Nutrient Digestibility and Blood Characteristics in Korean Black Goats (가시오갈피 지엽의 급여가 흑염소의 생산성, 영양소 소화율 및 혈액성상에 미치는 영향)

  • HwangBo, Soon;Jo, Ik-Hwan;Lee, Sung-Hoon;Kim, Seong-Kyu
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.26 no.4
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    • pp.239-248
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    • 2006
  • This study was conducted not only to investigate effects of different supplementation levels of Acanthopanax senticosus leaves on feed intakes, nutrient digestibility, nitrogen retention, and blood metabolites in Korean black goats but also to obtain basic data for nutritive value of Acanthopanax senticosus leaves and production of high quality functional animal products. Twelve Korean black goats were allotted to treatments in four groups of three goats per treatment and then they were housed in individual metabolism cages with completely random arrangements for 21 days. Four treatments were separated into controls and three different supplementation levels of Acanthopanax senticosus such as 10, 20 and 30%, respectively. For the chemical composition of experimental diets, crude protein (CP) contents of controls were 13.39% and those of supplementation treatments were lowered with increasing levels of Acanthopanax senticosus. Control groups tended to have higher acid detergent fiber (ADF) and neutral detergent fiber (NDF) contents as compared to supplementation groups, but non-fibrous carbohydrate (NFC) contents tended to be higher far supplementation groups than those for controls. Feed intakes had no significant difference among treatments, but digestible dry matter amounts were significantly higher for 20 and 30% supplementation groups than those for other treatments. Dry matter intakes per metabolic body weight and their ratio per body weight were highest in 20% group, but those of 40% groups were lowest (p<0.05). Crude protein, ADF and NDF digestibilities were significantly higher in Acanthopanax senticosus supplementation groups in comparison to controls (p<0.05), and in particular, they were increased with increasing supplementation levels of tranthopanax senticosus. Nitrogen retention was significantly higher for 20 and 30% treatments than those fur controls (p<0.05). Plasma urea nitrogen concentration was significantly lower for 30% supplementation group than those fur controls (p<0.05). Furthermore, plasma triglyceride concentration was significantly lower for Acanthopanax senticosus groups than those for controls (p<0.05). The results showed that supplemental level of 20% Acanthopnnax senticosus leaves to Korean black goats improved nutrient digestibility, nitrogen retention, and plasma urea nitrogen and triglyceride concentrations. Consequently, it might contribute to more efficient production of Korean black goats.

Clinicopathological Effects of Waterpepper (Persicaria hydropiper) on Ruminants (여뀌섭취가 반추수에 비치는 임상병리학적 영향)

  • Cho Myoung-Rae;Han Hong-Ryul
    • Journal of Veterinary Clinics
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    • v.6 no.2
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    • pp.227-259
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    • 1989
  • Waterpepper is a weed which grows on damp soil. especially near swamps, and in shallow water of ponds and ditches. It Is widespread throughout the country In abundant colonies. In the present experiments, possible toxic effects of waterpepper were investigated in ruminants. Pour cows were fed waterpepper ad libitum or by force in the from of green forage, hay and/or powder, 8 goats were administered in the form of methanol extract, and 4 goats, crude juice, into the lumen. Clinical signs were examined as well as urinalysis, hematology, serum chemical analysis, pH/blood gas analysis and chclinesterase activities following administration of waterpepper. Six goats which were administered the methanol extract or crude juice were sacrificed for pathological examinations., In addition to the clini copathological examinations, the chemical constituents of waterpepper were qualitively analyzed from the methanol extract and the Effects of the waterpepper crude juice were examined on the motility of rabbit duodenum and uterus. It is revealed that waterpepper contains steroids, terpenoids, flavonoids, tannin and essential oils in the methanol extract and nitrates in the crude juice. The crude juice of waterpepper relaxed the rabbit uterine and duodenal smooth muscles. The constraction of duodenum by acetylcholine or BaCl$_2$ were partially inhibited by pretreatment of the crude juice. However, the relaxation of duodenum by the crude juice was not blocked by the pretreatments of phenoxybenzamlne, propranolol, cocaine, reserpine and tetrodotoxin. The constituents of waterpepper to evoke elaxation of duodenal smooth muscle were stable to heat. The cows administered waterpepper showed common clinical symptoms such as acrid expression, restlessness, dullness, inappetence, anorexia, severe diarrhea, mild bloat and left displacement of abomasum, while bloody feces was shown in a cow. The goats administered the mothanol extract showed common clinical signs such as acrid expression, restlessness, dullness, inappetence and soft feces, while bloody feces was shown in a goat, A goat adminstered the crude juice showde bloody feces and diarrhea. Respiratory rates and heart beats were increased along with diarrhea in the experimental cows. The erythrocyte counts and MCHC were decreased whereas PCV, MCV and neutrophils were increased in the cows administered waterpepper. In goats administered methanol extract, there were decreases in erythrocytes, PCV and hemoglobin content, and an increase in MCHC. The goats ingester with the crude juice showed negligible changes in hematologic values compared with control group which was administered the same amount of water instead of the crude juice. The contents of serum calcium, Inorganic phosphorus, magnesium, Iron, glucose, cholesterol, total protein, triglycerides and phospholipids were tended to decrease in cows. In goats serum iron, glucose, triglycerides, cholesterol, BUN and phospholipids content were decreased while the content of sodium and chloride were increased after administration of the methamol extract The goats ingested with the crude juice did not show significant changes in serum chemical analysis. Even though there were some pathological findings such as hyperemia in the small intestines and kidneys and swelling of liver parenchymal cells, the values of serum AST, ALT, LDH, alkaline phosphatase, total bilirubin and creatinine did not change significantly. While proteins, hemoglobin and blood were detected in the urine of cows, urine pH, ketone bodies, glucose, bilirubin and urobilinogen content were normal or undetected. There were no significant changes in pH/bolld gas analysis data of cows and cholinesterase activities of plasma and erythrocytes of cows and goats ingested with waterpepper or the methanol extract. It is concluded that waterpepper irritates the gatrointestinal system, causes abdominal pain, relaxes the gastrointestinal smooth muscle and dilatates blood vessels supplied to the system. The irritation and relaxation may lead to abnormal fermentation, maldigestion and malabsorption of nutrients and result in diarrhea, body feces, mild bloat and left displacement of abomasum.

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Clinical Characteristics and Heart Rate Variability of Foreign Domestic Violence Victims in Korea (국내 거주 외국인 가정폭력 피해 여성의 임상적 특징 및 심박변이도)

  • Kim, Kyu-Lee;Choi, Jin-Sook;Jang, Yong-Lee;Lee, Hae-Woo;Sim, Hyun-Bo
    • Sleep Medicine and Psychophysiology
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    • v.24 no.1
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    • pp.46-54
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    • 2017
  • Objectives: Domestic violence is related to many psychiatric diseases, such as depression, anxiety disorder, and PTSD. Heart rate variability (HRV) is an index of autonomic control of the heart and is related to cardiovascular and emotional disorders. Although there have been some studies on the effects of domestic violence on women's mental health, relatively little information is available on HRV in this population. The aim of this study is to investigate demographic data, psychological features, and HRV in female victims of domestic violence and difference between Korean and foreign female victims. Methods: A total of 210 female victims of domestic violence (166 Korean women and 44 foreign women) were recruited for this study. Psychological symptoms were measured using the Hamilton Rating Scale for Anxiety (HAM-A), Hamilton Rating Scale for Depression (HAM-D), and Impact of Event Scale-Revised (IES-R). HRV measures were assessed by time-domain and frequency-domain analyses. Results: The mean score of HAM-A was 13.81, that of HAM-D was 12.92, and that of IES-R was 33.61 ; there were no significant differences between Korean and foreign women in these measures. In HRV time domain analyses, approximate entropy (ApEn) was significantly increased in foreign women compared to the Korean women. The square root of the mean of the sum of the squares of differences between adjacent NN intervals (RMSSD) was significantly decreased in foreign women compared to Korean women. There were no significant differences in the other HRV variables between Korean and foreign women. Conclusion: Female victims of domestic violence in Korea are associated with depression, anxiety, and PTSD symptoms. The physiologic factors of a female victim's nationality could be related to higher ApEn and lower RMSSD in foreign female victims. These findings have important implications for future study to study the relationships among ethnic and environmental factors and HRV variables.

A Polarization-based Frequency Scanning Interferometer and the Measurement Processing Acceleration based on Parallel Programing (편광 기반 주파수 스캐닝 간섭 시스템 및 병렬 프로그래밍 기반 측정 고속화)

  • Lee, Seung Hyun;Kim, Min Young
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.8
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    • pp.253-263
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    • 2013
  • Frequency Scanning Interferometry(FSI) system, one of the most promising optical surface measurement techniques, generally results in superior optical performance comparing with other 3-dimensional measuring methods as its hardware structure is fixed in operation and only the light frequency is scanned in a specific spectral band without vertical scanning of the target surface or the objective lens. FSI system collects a set of images of interference fringe by changing the frequency of light source. After that, it transforms intensity data of acquired image into frequency information, and calculates the height profile of target objects with the help of frequency analysis based on Fast Fourier Transform(FFT). However, it still suffers from optical noise on target surfaces and relatively long processing time due to the number of images acquired in frequency scanning phase. 1) a Polarization-based Frequency Scanning Interferometry(PFSI) is proposed for optical noise robustness. It consists of tunable laser for light source, ${\lambda}/4$ plate in front of reference mirror, ${\lambda}/4$ plate in front of target object, polarizing beam splitter, polarizer in front of image sensor, polarizer in front of the fiber coupled light source, ${\lambda}/2$ plate between PBS and polarizer of the light source. Using the proposed system, we can solve the problem of fringe image with low contrast by using polarization technique. Also, we can control light distribution of object beam and reference beam. 2) the signal processing acceleration method is proposed for PFSI, based on parallel processing architecture, which consists of parallel processing hardware and software such as Graphic Processing Unit(GPU) and Compute Unified Device Architecture(CUDA). As a result, the processing time reaches into tact time level of real-time processing. Finally, the proposed system is evaluated in terms of accuracy and processing speed through a series of experiment and the obtained results show the effectiveness of the proposed system and method.

A Study on a Quantitative Method in Estimating Forest Effects for Streamflow Regulation (II) - Mainly Dealing with Application of Coefficient for Slope Roughness - (삼림이수기능(森林理水機能)의 정량적(定量的) 평가방법(平價方法)에 관한 연구(硏究)(II) - 조도계수(粗度係數)의 응용(應用)을 중심(中心)으로 -)

  • Lee, Heon Ho
    • Journal of Korean Society of Forest Science
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    • v.81 no.4
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    • pp.337-345
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    • 1992
  • In this research, a kinematic wave model was applied for the runoff analysis, Regulation of streamflow was estimated by the calibration of roughness coefficient as a parameter. The data analyzed were obtained from Ananomiya and Shirasaka experimental basins at Tokyo University Forest in Aichi. Estimation methods and characteristics of roughness coefficient as a evaluation method of hydrological function of forest are summarized as follows ; 1. Roughness coefficient($N_s$) indicates the resistance of hillslope to the flowing water of surface runoff. There exists an hypothesis that resistance of hillslope to flowing water increase with the growth forest and development of the $A_o$ layer. 2. Roughness coefficient($N_s$) was estimated by the parameter when the stream direct runoff was calculated by using the kinematic wave. 3. Secular change of '$N_s$' in ananomiya has a curve which has an upper limit and increases exponentially near the limit. The curve quickly increased from 1935 to 1945 when results of afforestation for erosion control were thought to be effective. On the other hand, slight increase of '$N_s$' in Shirasaka indicates that there was not such a big change in the surface of soil layer. 4. The increase of '$N_s$' was related with decrease of direct runoff and increase of base flow. It was recognized that the rate of direct runoff decreased with the improvement of forest physiognomy and the rate of base flow was increased. But absolute value of water runoff per one storm decreased in chronological order.

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Effects of Climatic Condition in September on Pine-mushroom(Tricholoma matsutake) Yield and a Method for Overcoming the Limiting Factors in Korea (한국(韓國)에서 9월(月)의 기상인자(氣象因子)가 송이 발생(發生)에 미치는 영향(影響)과 그 극복방안(克服方案))

  • Park, Hyun;Kim, Kyo-Soo;Koo, Chang-Duck
    • Journal of Korean Society of Forest Science
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    • v.84 no.4
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    • pp.479-488
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    • 1995
  • Relationships between pine-mushroom(Tricholoma matsutake) yield and important climatic factors for the yield(such as monthly precipitation, relative humidity, temperature, and radiation percentage) were examined to find out limiting factors for pine-mushroom production and to develop a method for overcoming the factors by analyzing the yield and climate data for 17 years collected from 18 main regions of pine-mushroom production. Although there were variations among the production regions, climatic condition of September was the most significant factor for pine-mushroom yield in general, and the degrees of importance of each climatic factors were different among the production regions. Mean minimum temperature of September was positively correlated with pine-mushroom yield($$r^2{\geq_-}0.41$$) at the 1% level, of which were 9 regions such as Youngduck, Uljin, Samchuck, Bongwha arid so on. In these regions, vegetation control was expected to be effective for pine-mushroom production by allowing much sunlight penetration to the pine stand, which may increase soil temperature and keeping the temperature around the fungal colony in soil. Precipitation during September was positively correlated with pine-mushroom yield($$r^2{\geq_-}0.41$$) at Namwon, Moonkyung and Sangju. Thus, irrigation around fungal colony in dry soil during September would be effective for enhancing mushroom yield at the regions. Pine-mushroom yield of 1994 was quite low, similar to that of 1993, due to serious drought. In this period, we could manifest the possibility of enhancing pine-mushroom yield by irrigation for overcoming drought at Moonkyung and Keochang regions.

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The Relationship between Entrepreneurial Education and Entrepreneurial Intentions : Focusing on Moderating Effects of Entrepreneurial Orientation and Environmental Factors (창업교육과 창업의지의 관계: 기업가 지향성과 환경적 요인의 조절효과)

  • Lee, Jae-Seok;Lee, Sang-Myung
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.10 no.3
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    • pp.61-74
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    • 2015
  • This study attempts to empirically examine the influence of entrepreneurial education in university on entrepreneurial intentions of undergraduate and graduate students as potential entrepreneur and new moderating factors on the relationship between entrepreneurial education and entrepreneurial intentions. We suggested EO(innovativeness, risk-taking propensity, proactiveness and locus of control) and environmental factors(entrepreneurial family background and resource accessibility) as new moderating factors in the relationship. For this study, the following research questions are raised : First, is there a significant difference in entrepreneurial intentions of enrolled and unenrolled students in entrepreneurial education? Second, does entrepreneurial education affect entrepreneurial intentions positively? Finally, do EO and environmental factors have moderating effects in the relationship between entrepreneurial education and entrepreneurial intentions? In order to test our research model, the current study collected data from 265 undergraduate and graduate students who are majoring in natural sciences or engineering in Seoul National Univ., Hanyang Univ., and KAIST. To investigate our research questions and hypotheses, independent-sample T-test and hierarchical regression analysis were employed. The results of empirical analysis revealed that entrepreneurial education positively related to entrepreneurial intentions and that the relationship between entrepreneurial education and entrepreneurial intentions moderated by EO and environmental factors. First, the result showed the significant difference in entrepreneurial intentions between enrolled and unenrolled students in entrepreneurial education. Entrepreneurial intentions of students who enrolled entrepreneurial education was higher than others. Second, entrepreneurial education affected the entrepreneurial intentions positively. Finally, the moderating effects of innovativeness, risk-taking propensity, proactiveness and entrepreneurial family background among investigated six moderators were significant. entrepreneurial education-entrepreneurial intentions relationship was even stronger under high innovativeness and high proactiveness. But risk-taking propensity and entrepreneurial family background decreased the effect of entrepreneurial education on entrepreneurial intentions.

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The Different View Point of Child Education Center Food Service Program between the Parents and the Teachers (유아교육기관에서의 급식관리 실태에 대한 교사 및 학부모의 인식 연구)

  • Lee, Young-Mee
    • Korean Journal of Community Nutrition
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    • v.10 no.5
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    • pp.654-667
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    • 2005
  • To survey the different view points about food service programs among parents and teachers, 2 types of questionnaires, which consisted of attitude, perception, satisfaction and demand of the food service program in child education centers, were used. The data was collected from 2450 parents and 450 teachers who attended a child education center in 16 provinces, nationwide. SPSS was used for descriptive analysis and ANOVA test and $X^2-test$. The frinding results were as follows. 1. The average serving size of meal (lunch) were 80 meals per day and 167 meals per day at large institutions. Mean cost of snacks was 14,709 won per month and mean costs of lunch were 29,319 won per month. The mean price was not significantly different according to the scale of institution. The numbers of servings of lunch, morning snack and afternoon snack were 5, 3.4 and 3.5 times per week each. $56.4\%$ of the institutions served meals to children in classrooms, but the national/public institutions, which were attending elementary school, served meals in a dining place in the elementary school. 2. Teacher controlled serving portion size of snacks $(79.6\%)$ and lunch $(88.8\%)\;and\;30.1\%$ of teacher did not allow leaving lunch food. The ratio of knowing about preserved meals of the teacher who worked at a small institution was significantly higher than the teacher who worked at large institutions (p<0.01). 3. Between parents and teachers, several different view points about school lunch programs were detected. Most parents and teachers wanted that the school lunch to be fully cooked and served at the child education institution itself, but $12.2\%$ of parents and $14.4\%$ of teachers wanted a catering service. The teachers group preferred 'lunch box from home' and 'home partially prepared lunch' as an ideal meal serving type than the parent groups (p<0.01). And there were significantly different view points about price factors in school meals, teachers group highly answered that operating expenses must be added in meal prices. 4. The teacher groups' priorities of education activities during meal time were a significantly lower score than parents group in overall education activities. Teacher and parent groups pointed out that individual sanitation activities were most important of the education activities during meal time, but promoting good eating habits was the lowest score in both groups. 5. 'Improving taste and food quality' was most urgent in food service at child education centers, but there were significantly different view points between parent groups $(64.5\%)$ and teacher groups $(43.8\%)\;(p<0.05)$. They answered at a lower percent in 'employee qualified person' and 'cost control' point to improve food service, but there were also different opinions between the two groups (p<0.01). 6. As to the matter of the advantages and disadvantages of catering services, two group answered that the advantages of a catering service were 'convenience' and 'to solve facilities and labor problems', disadvantages were 'lower in food freshness' and 'sanitation problems'. There were also several different view pionts in catering services, the parents groups were more anxious about food sanitation than teachers. This study found several different view points about school food services among parents and teachers. To improve food services at child education institutions, there is a need to adjust the differences between the two groups through interactive communication channels and education and to employ dietitians as taking charge of adjusting roles between the two groups.

A Study on Dosimetry for Small Fields of Photon Beam (광자선 소조사면의 선량 측정에 관한 연구)

  • 강위생;하성환;박찬일
    • Progress in Medical Physics
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    • v.5 no.2
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    • pp.57-68
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    • 1994
  • Purpose : The purposes are to discuss the reason to measure dose distributions of circular small fields for stereotactic radiosurgery based on medical linear accelerator, finding of beam axis, and considering points on dosimetry using home-made small water phantom, and to report dosimetric results of 10MV X-ray of Clinac-18, like as TMR, OAR and field size factor required for treatment planning. Method and material : Dose-response linearity and dose-rate dependence of a p-type silicon (Si) diode, of which size and sensitivity are proper for small field dosimetry, are determined by means of measurement. Two water tanks being same in shape and size, with internal dimension, 30${\times}$30${\times}$30cm$^3$ were home-made with acrylic plates and connected by a hose. One of them a used as a water phantom and the other as a device to control depth of the Si detector in the phantom. Two orthogonal dose profiles at a specified depth were used to determine beam axis. TMR's of 4 circular cones, 10, 20, 30 and 40mm at 100cm SAD were measured, and OAR's of them were measured at 4 depths, d$\sub$max/, 6, 10, 15cm at 100cm SCD. Field size factor (FSF) defined by the ratio of D$\sub$max/ of a given cone at SAD to MU were also measured. Result : The dose-response linearity of the Si detector was almost perfect. Its sensitivity decreased with increasing dose rate but stable for high dose rate like as 100MU/min and higher even though dose out of field could be a little bit overestimated because of low dose rate. Method determining beam axis by two orthogonal profiles was simple and gave 0.05mm accuracy. Adjustment of depth of the detector in a water phantom by insertion and remove of some acryl pates under an auxiliary water tank was also simple and accurate. TMR, OAR and FSF measured by Si detector were sufficiently accurate for application to treatment planning of linac-based stereotactic radiosurgery. OAR in field was nearly independent of depth. Conclusion : The Si detector was appropriate for dosimetry of small circular fields for linac-based stereotactic radiosurgery. The beam axis could be determined by two orthogonal dose profiles. The adjustment of depth of the detector in water was possible by addition or removal of some acryl plates under the auxiliary water tank and simple. TMR, OAR and FSF were accurate enough to apply to stereotactic radiosurgery planning. OAR data at one depth are sufficient for radiosurgery planning.

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