• Title/Summary/Keyword: continuous object

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The Recovery Effects of Joojakwhan - A Traditional Korean Medical Poly-herbal Drug for the Cognitions and Motor Functions in Mild Stroke Rat Model by Using Transient Middle Cerebral Artery Occlusion (주작환(朱雀丸)이 일시적 국소 뇌허혈 유발 백서(白鼠)에 대한 인지 및 운동기능 회복에 미치는 효과)

  • Kim, Bo-Eun;Kang, Seok-Bong;Chung, Dae-Kyoo
    • Journal of Oriental Neuropsychiatry
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    • v.24 no.4
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    • pp.419-434
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    • 2013
  • Objectives: The object of this study is to observe the cognition and motor function recovery effects of Joojakwhan (JJW), a traditional Korean poly-herbal formula for treating various neuropsychiatric diseases such as dementia, for the mildly stroke rats, with 60 minutes of reperfusion transient middle cerebral artery occlusion (tMCAO). Methods: In the present study, 125, 250 and 500 mg/kg of JJW were orally administered, once per day for 10 continuous days 2 hours after the tMCAO. The body weight changes, infarct sizes under 2% 2, 3, 5-triphenyl tetrazolium chloride (TTC) stain, sensorimotor functions and cognitive motor behavior tests were serially monitored with cerebral caspase-3 and cleaved poly (ADP-ribose) polymerase (PARP)-immunoreactivities and histopathological changes. The effects of tMCAO on sensorimotor functions were evaluated by using of limb placing and body-swing tests, and the cognitive motor behaviors were also observed with water maze tests. Results: From the results of tMCAO, with marked decreases of body weights, disorders of sensorimotor functions increases the limb placing test scores, and decrease the numbers and percentages of body swings to the ipsilateral sides. The cognitive motor behaviors increases the distances and time to reach the escape platform which included the inhibitions of the decreases with repeated trials that were observed with focal cerebral cortex infarct volumes. In addition, the marked increases of the atrophy, numbers of degeneration, caspase-3- and PARP-immunoreactive cells around peri-infarct ipsilateral cerebral cortex were also observed in tMCAO controls when compared with the sham control rats, respectively. Conclusions: The results obtained from this study suggest that oral administrations of JJW indicate obvious cognitions and motor function recoveries of the rats with tMCAO, mild strokes, which are mediated by neuro-protective effects through known antioxidant effects of components.

The Review of Exposure Index in Digital Radiography and Image Quality (디지털 영상에서 화질관리에 관한 노출지수(EI)의 유용성 연구)

  • Yang, Sook;Han, Jae Bok;Choi, Nam Gil;Lee, Seong Gil
    • Journal of Radiation Protection and Research
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    • v.38 no.1
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    • pp.29-36
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    • 2013
  • The aim of this study was to determine the correlation between exposure index (EI) and dose factors related to radiation dose optimization in digital radiography (DR) system. Two phantoms with built-in regional test object for quantitative assessment of images were used to produce image signals that acquired in chest radiography background. EI and entrane surface dose (ESD) increased proportionally with rise of radiation dose (kVp, mAs) in both DR and CR systems. Especially, DR detector was effective to form good contrast and hence, reached easily to improvement of image quality with minimal dose changes. It made operators possible to expect the accuracy of EI values deeply related to absorbed dose of the detector. The evaluation of images was obtained specially employed calculation of noise to signal ratio (NSR) and contrast to noise ratio (CNR). These measurements were performed for how exposure factors affect image quality. NSR was inversely proportional to kVp and mAs and low NSR represented high signal detection efficiency. Consequently, EI values was the measure of the amount of exposure received by the image receptor and it was proportional to exposure factors. Therefore the EI in a recommended range from manufacturer can offer optimal image quality. Also, continuous monitoring of EI values in the digital radiography can reduce the unnecessary patient dose and help the quality control of the system.

A Comparative Study of Korea and Japan Relating to the Welfare Business Operation of Pension Accumulation (연금적립금의 복지사업 운용에 관한 한.일 비교연구)

  • Chung, Ki-Ryong
    • Korean Journal of Social Welfare
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    • v.35
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    • pp.345-374
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    • 1998
  • The purpose of this study is to contribute the improvement of national welfare by presenting of pension welfare business of Korea and Japan. The reason why I take the management of Japan's pension accumulation as the object of comparative study is that the history of pension system of Japan is relatively longer than that of Korea. First of all, National Pension Fund comes into use for public sector, financial sector, and welfare sector, The scale of pension management for welfare sector is 50 small. Therefore, the study for welfare business investment reflecting the intentions of pension entries and pensioners is needs of times. This study defines the concept of welfare investment business and prospects welfare investment business of the future on the basis of Japanese experiences, and then suggests the direction of efficient propulsion of welfare investment business to the reasonable decision-makers. Especially this study redefine the concept of welfare investment business on the basis of pension entry's social benefits which are composed of pension entry's gains and pensioner's gain. Of course, welfare investment business has to be presupposed the stability of pension system and the continuous contribution to national economy. Thus, in order to efficiently perform welfare business, the policy-making for national welfare improvement has to be established after the good of business is set up like the results of this study.

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Suppressing Effects of Sowhalrack-dan(Xiǎohuóluò-dān) on Freund's Complete Adjuvant Induced Arthritic Rats (Adjuvant 유발(誘發) 류마티스 관절염(關節炎)에 대한 소활락단(小活絡丹)의 억제(抑制) 효과(效果))

  • Yun, Sun-Mo;Jeong, Man-Jin;Kwon, O-Gon;Woo, Chang-Hoon;An, Hee-Duk
    • Journal of Korean Medicine Rehabilitation
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    • v.21 no.1
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    • pp.97-114
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    • 2011
  • Objectives : The object of this study is to observe the favorable anti arthritic effects of Sowhalrack-dan($Xi\check{a}ohu\acute{o}lu\grave{o}-d\bar{a}n$)(SWRD), which has been traditionally used in Korean medicine to treat rheumatoid arthritis on Freund's complete adjuvant(FCA) induced arthritic Wistar rats. Methods : Rheumatoid arthritis was induced by intradermal injection of FCA(10 mg in 1 ml paraffin oil 0.1 ml/rats). Each of 8 rats showing regular ankle circumferences per group were selected in 14 days after FCA treatment to confirm the induction of rheumatoid arthritis. 300, 150 or 75 mg/kg of SWRD was orally administered once a day for 14 days from 14 days after FCA treatments. Dexamethasone was intraperitoneally administered 15 mg/kg, once a day for 14 days from 14 days after FCA treatments. Rats were sacrificed after 14 days of continuous oral treatment of SWRD or intraperitoneal administration of dexamethasone, and changes were observed; the body weight, knee circumferences, gross arthritis score, inflammatory tissue $prostaglandin(PG)E_2$ levels and cartilage collagen, glucosaminoglycans compositions - chondroitin sulphate, heparin sulphate and hyaluronic acid in the present study. Results : As results of FCA treatment, classic rheumatoid arthritis featuring dramatical decreases on the body weights, cartilage collagen contents and bone glucosaminoglycans - chondroitin sulphate, heparin sulphate and hyaluronic acid contents. Also, it increases the knee circumferences, gross arthritis scores and inflammatory tissue $PGE_2$ levels. However, these changes from FCA induced rheumatoid arthritis were clearly reduced due to the dexamethasone and both two different dosages of SWRD, 300 and 150 mg/kg in the present study. Although FCA induced arthritis were more favorably inhibited by treatment of dexamethasone 15 mg/kg compared to SWRD 300 mg/kg, marked decreases of body weights were detected in dexamethasone 15 mg/kg treated rats. Conclusions : The results obtained in this study suggest that over 150 mg/kg of SWRD showed favorable anti-arthritic effects on the FCA induced arthritis mediated by suppression of $PGE_2$. However, detailed mechanism studies are needed with the screening of the biological active compounds in SWRD. Although FCA induced arthritis were more favorably inhibited by treatment of dexamethasone 15 mg/kg compared to SWRD 300 mg/kg, marked decreases of body weights were detected in dexamethasone 15 mg/kg treated rats, in the present study.

Evaluation of Shear Capacity on PC Girder-PC Beam Joint (PC 큰 보-PC 작은 보 접합부의 전단성능 평가)

  • Moon, Jeong Ho;Oh, Young Hun;Lim, Jae Hyung
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.15 no.6
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    • pp.166-174
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    • 2011
  • The object of this study is to evaluate the structural shear capacity of the PC girder-PC beam joint. The dapped end of PC beam and the ledger of PC girder are usually designed to design load. If the end of PC beam can be designed with continuous end, the dapped end of PC beam and the ledger of PC girder do not need to resist to all loads except dead load and construction load. The experimental program was carried out with 7 specimens containing the variable factors as the anchored method of the hanger bar, design load, be or not exist of ledger bars. As a result, the continuity of the dapped end and the ledger were ensured their safety although the design load was only the dead load and the construction load. The shear critical section was expanded toward the effective depth d, the distance from the supported position of the beam. If the ledger is designed according to PCI Design Handbook, the structural system of the ledger is as to the cantilever slab system. But the ledger of this study is as to the 3 side fixed slab system. Therefore the design of the ledger by PCI Design Handbook will lead to highly conservative results.

Effects of Lonicerae Flos Extracts on LPS-induced Acute Lung Injury (금은화가 LPS로 유발된 급성 폐 손상에 미치는 영향)

  • Yi, Chang-Geon;Choi, Hae-Yun;Park, Mee-Yeon;Kim, Jong-Dae
    • Journal of Society of Preventive Korean Medicine
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    • v.15 no.1
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    • pp.49-69
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    • 2011
  • Objective : The object of this study was to observe the effects of Lonicerae Flos (LF) aqueous extracts on lipopolysaccharide (LPS)-induced rat acute lung injury. Method : Five different dosages of LF extracts were orally administered once a day for 28 days before LPS treatments, and then all rats were sacrificed after 5 hour-treatment of LPS. Eight groups of 16 rats each were used in the present study. The following parameters caused by LPS treatment were observed ; body weights, lung weights, pulmonary transcapillary albumin transit, arterial gas parameters (pH, $PaO_2$ and $PaCO_2$) bronchoalveolar lavage fluid (BALF) protein lactate dehydrogenase (LDH), and proinflammatory cytokines tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$), interleukin-$1{\beta}$ (IL-$1{\beta}$) contents, total cell numbers, neutrophil and alveolar macrophage ratios, lung malondialdehyde (MDA), myeloperoxidase (MPO), proinflammatory cytokines TNF-${\alpha}$ and IL-$1{\beta}$ contents. In addition, the histopathologic changes were observed in the lung in terms of luminal surface of alveolus, thickness of alveolar septum, number of polymorphonuclear neutrophils. Result : As results of LPS-injection, dramatical increases in lung weights, pulmonary transcapillary albumin transit increases, increases in $PaCO_2$, decreases in pH of arterial blood and $PaO_2$, increases of BALF protein, LDH, TNF-${\alpha}$ and IL-$1{\beta}$ contents, total cells, neutrophil and alveolar macrophage ratios, TNF-${\alpha}$ and IL-$1{\beta}$ contents increases were detected with decreases in LSA and increases of alveolar septum and PMNs numbers, respectively as compared with intact control. These are means that acute lung injuries (resembling acute respiratory distress syndrome) are induced by treatment of LPS mediated by inflammatory responses, oxidative stress and related lipid peroxidation in the present study. However, these LPS-induced acute lung injuries were inhibited by 28 days continuous pretreatment of 250 and 500mg/kg of LF extracts. Because of lower three dosages of LF treated groups, 31.25 and 62.5 and 125mg/kg did not showed any favorable effects as compared with LPS control, the effective dosages of LF in LPS-induced acute lung injuries in the present study, is considered as about 125mg/kg. The effects of 250mg/kg of LF extracts showed almost similar effects with ${\alpha}$-lipoic acid 60mg/kg in preventing LPS-induced acute lung injuries. Conclusion : It seems that LF play a role in protecting the acute respiratory distress syndrome caused by LPS.

Prediction of Land Surface Temperature by Land Cover Type in Urban Area (도시지역에서 토지피복 유형별 지표면 온도 예측 분석)

  • Kim, Geunhan
    • Korean Journal of Remote Sensing
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    • v.37 no.6_3
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    • pp.1975-1984
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    • 2021
  • Urban expansion results in raising the temperature in the city, which can cause social, economic and physical damage. In order to prevent the urban heat island and reduce the urban land surface temperature, it is important to quantify the cooling effect of the features of the urban space. Therefore, in order to understand the relationship between each object of land cover and the land surface temperature in Seoul, the land cover map was classified into 6 classes. And the correlation and multiple regression analysis between land surface temperature and the area of objects, perimeter/area, and normalized difference vegetation index was analyzed. As a result of the analysis, the normalized difference vegetation index showed a high correlation with the land surface temperature. Also, in multiple regression analysis, the normalized difference vegetation index exerted a higher influence on the land surface temperature prediction than other coefficients. However, the explanatory power of the derived models as a result of multiple regression analysis was low. In the future, if continuous monitoring is performed using high-resolution MIR Image from KOMPSAT-3A, it will be possible to improve the explanatory power of the model. By utilizing the relationship between such various land cover types considering vegetation vitality of green areas with that of land surface temperature within urban spaces for urban planning, it is expected to contribute in reducing the land surface temperature in urban spaces.

Development of Modeling Technique for Prediction of Driving Force and Kinetic Resistance of Agricultural Forklift (농업용 포크리프트의 구동력 및 운동저항 예측을 위한 모델링 기법 개발)

  • Jo, Jae-hyun;Kim, Jun-tae;Jeong, Jin-hyoung;Chang, Young-yoon;Park, Won-yeop;Lee, Sang-sik
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.12 no.3
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    • pp.299-305
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    • 2019
  • This study was initiated to solve the difficulties of aged and female workers in agriculture society due to aging and demise of young people. In the case of the conventional elevated lift, the risk of exposure to uneven road or work environment, not the difficulty of professional qualification and operation, and the risk of exposure to the uneven road or working environment, were also studied based on previous researches so that women could easily and efficiently perform productive agriculture. First, the simulation was carried out through the prediction model of traction performance using the object of agricultural forklift, and the soil of the Kimhae city in Gyeongnam (34.125kPa, internal friction angle 35.294deg, external friction angle 13.620deg, Adhesion force 5.750 kPa, average cone index 0-15 cm cl, 1001.8 kPa). In the case of the forklift for simulation, the driving force and the kinetic resistance prediction modeling of the agricultural electric forklift are modeled. Based on this model, the motor control drive adopts the 1232E model, which is a drive dedicated to AC motor, and divides the two drivers into master and slave And the model for the simulation was designed to control motor drive, hydraulic drive, and various outputs on the main PCB. The simulation model is undergoing continuous simulation, modification and supplementation. Based on this research, we will continue research for development of safer and more efficient agricultural electric forklift.

Comparison of Open Source based Algorithms and Filtering Methods for UAS Image Processing (오픈소스 기반 UAS 영상 재현 알고리즘 및 필터링 기법 비교)

  • Kim, Tae Hee;Lee, Yong Chang
    • Journal of Cadastre & Land InformatiX
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    • v.50 no.2
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    • pp.155-168
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    • 2020
  • Open source is a key growth engine of the 4th industrial revolution, and the continuous development and use of various algorithms for image processing is expected. The purpose of this study is to examine the effectiveness of the UAS image processing open source based algorithm by comparing and analyzing the water reproduction and moving object filtering function and the time required for data processing in 3D reproduction. Five matching algorithms were compared based on recall and processing speed through the 'ANN-Benchmarks' program, and HNSW (Hierarchical Navigable Small World) matching algorithm was judged to be the best. Based on this, 108 algorithms for image processing were constructed by combining each methods of triangulation, point cloud data densification, and surface generation. In addition, the 3D reproduction and data processing time of 108 algorithms for image processing were studied for UAS (Unmanned Aerial System) images of a park adjacent to the sea, and compared and analyzed with the commercial image processing software 'Pix4D Mapper'. As a result of the study, the algorithms that are good in terms of reproducing water and filtering functions of moving objects during 3D reproduction were specified, respectively, and the algorithm with the lowest required time was selected, and the effectiveness of the algorithm was verified by comparing it with the result of 'Pix4D Mapper'.

Effect of environmental enrichment for piglets in the nursery phase

  • Padilha-Boaretto, Joselaine Bortolanza;Groff-Urayama, Priscila Michelin;Einsfeld, Suelen Maria;de Souza, Cleverson;Mendes, Angelica Signor;Maeda, Emilyn Midori;Takahashi, Sabrina Endo
    • Animal Bioscience
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    • v.34 no.1
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    • pp.154-160
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    • 2021
  • Objective: The effect of environmental enrichment on the behaviour of piglets in the nursery phase was evaluated. Methods: A total of 450 hybrid pigs (21 day old), including both females and uncastrated males, weighing approximately 6 kg, were distributed in a completely randomised design with 3 treatments and 3 replicates of 50 animals each. The treatments were: i) pen without environmental enrichment (control), ii) treatment consisting of continuous environmental enrichment (CEE) with rubber balls throughout the experimental period, and iii) treatment consisting of environmental enrichment with washed balls (EEWB) during the whole experimental period which were removed daily for washing. For the behavioural evaluation, 10 animals were randomly selected per replicate. The behavioural assessments were performed once a week, from 8 am to 6 pm, using images captured with a video camera. The data were submitted to non-parametric analyses, the means were compared using the Bonferroni test, and Person's correlations were also calculated. Results: A statistical difference (p = 0.001) was observed in the B5 (playful) behaviour; the animals in the EEWB treatment group had a higher frequency of this behaviour than animals in the control treatment group. The animals in the control group showed a higher frequency of B7 behaviour (lying down) (p = 0.026) than those in the EEWB and CEE treatment groups. The animals in the control group had a higher frequency of the B9 (belly nosing) behaviour than those in the EEWB group (p = 0.015). There was a tendency towards a higher frequency of behaviour B3 (walking in the pen) (p = 0.067) when the animals received the control treatment than treatments EEWB or CEE. Conclusion: The use of an enriching object improved the animal welfare and altered the correlation between the evaluated behaviours compared to the animals that did not have environmental enrichment.