• Nutrition Research and Practice
• /
• 제3권3호
• /
• pp.200-207
• /
• 2009

This study examined the effects of com gluten (CG) and its hydrolysate consumptions on weight reduction in rats fed a high-fat diet. Eight-month-old male Sprague-Dawley rats (n=40) were fed a high-fat diet (40% calorie as fat) for 4 weeks. They were then randomly divided into four groups and fed the isocaloric diets with different protein sources for 8 weeks. The protein sources were casein (control group), intact CG (CG group), CG hydrolysate A (CGHA group, 30% of protein as peptides and 70% as free amino acids) and CG hydrolysate P (CGHP group, 93% of protein as peptides and 7% as free amino acids). Body weight gain, adipose tissue weights, nitrogen balance, absorptions of energy, protein and fat, lipid profiles in plasma, liver and feces and hepatic activities of camitine palmitoyl transferase (CPT), fatty acid synthase (FAS), malic enzyme (ME) and glucose-6-phosphate dehydrogenase (G6PDH) were assessed. The CGHA diet had the highest amount of BCAAs, especially leucine, and most of them existed as free amino acid forms. The CGHA group showed significant weight reduction and negative nitrogen balance. Protein absorption and apparent protein digestibility in the CGHA group were significantly lower than those in other groups. Adipose tissue weights were the lowest in the CGHA group. Activity of CPT tended to be higher in the CGHA group than in other groups and those of FAS, ME and G6PDH were significantly lower in the CGHA group than in other groups. In conclusion, the CGHA diet which had relatively high amounts of free amino acids and BCAAs, especially leucine, had a weight reduction effect by lowering adipose tissue weight and the activities of FAS, ME and G6PDH in experimental animals, but it seemed to be a negative result induced by lowering protein absorption, increasing urinary nitrogen excretion and protein catabolism.

• KIEAE Journal
• /
• 제14권2호
• /
• pp.3-10
• /
• 2014

Impact by estimation error of hourly horizontal global solar radiation in a weather file on building energy performance was investigated in this study. There are a number of weather parameters in a given weather file, such as dry-bulb, wet-bulb, dew-point temperatures; wind speed and direction; station pressure; and solar radiation. Most of them except for solar radiation can be easily obtained from weather stations located on the sites worldwide. However, most weather stations, also including the ones in South Korea, do not measure solar radiation because the measuring equipment for solar radiation is expensive and difficult to maintain. For this reason, many researchers have studied solar radiation estimation models and suggested to apply them to predict solar radiation for different weather stations in South Korea, where the solar radiation is not measured. However, only a few studies have been conducted to identify the impact caused by estimation errors of various solar radiation models on building energy performance analysis. Therefore, four different weather files using different horizontal global solar radiation data, one using measured global solar radiation, and the other three using estimated global solar radiation models, which are Cloud-cover Radiation Model (CRM), Zhang and Huang Model (ZHM), and Meteorological Radiation Model (MRM) were packed into TRY formatted weather files in this study. These were then used for office building energy simulations to compare their energy consumptions, and the results showed that there were differences in the energy consumptions due to these four different solar radiation data. Additionally, it was found that using hourly solar radiation from the estimation models, which had a similar hourly tendency with the hourly measured solar radiation, was the most important key for precise building energy simulation analysis rather than using the solar models that had the best of the monthly or yearly statistical indices.

• Toxicological Research
• /
• 제22권4호
• /
• pp.453-458
• /
• 2006

This study was carried out to investigate the acute toxicity of surfactin C in mice. Surfactin C was administered orally at does of 0, 381, 610, 977, 1562 and 2500 mg/kg. Number of deaths, clinical signs, body weights, feed and water consumptions, and biochemical examinations were investigated for 14 days after single oral administration of surfactin C. $LD_{50}$ value was over 2500mg/kg in mice. In addition, no differences were found between control and treated groups in clinical signs, body weight gains, hematology, serum chemistry, feed and water consumptions. The results indicate that surfactin C did not show any toxic effects at 2500 mg/kg in mice.

• Toxicological Research
• /
• 제22권4호
• /
• pp.339-348
• /
• 2006

Misaengtang (MST), a formula of Korean herbal medicines, has been used as a weight-controlling recipe. We have investigated two experiment of body weight regulation by MST In rats. i) The anti-obesity effect of MTS on a high fat diet-induced obesity, male Sprague-Dawley rats were fed with a high-fat diet containing 30% in the absence or presence of MST (0.3, 1 or 3%) or a reference orlistat (0.05%) for 6 weeks. ii) weight-decrease effect of MST on normal diet, same animal were fed with a normal diet in the absence or presence of MST (3%) for 6 weeks. And the body weights, daily feed and water consumptions, organ weights, fat weights serum biochemistry were measured. In both experiments, MST and orlistat did not affect the body weight gain. But orlistat significantly increased the feed and water consumptions, leading to low-feed efficiency, and orlistat markedly reduced abdominal, paratesticular and perirenal fat weights, although increased the kidney weights. In MST, low dose (0.3%) of MST decreased the perirenal fat and increased the kidney weights in rats fed HFD, and MST 3% decreased the abdominal fat weights in rats fed normal diet. In addition, Orlistat caused changes in parameters of hepatotoxicity (AST and glucose), nephrotoxicity (BUN and B/C ratio) and lipid metabolism (HDL and triglycerides). In comparison, MST decreased AST, ALP and ALT, the hepatotoxicity markers, and somewhat improved the hepatic fatty degeneration. Taken together, it is suggested that MST does not exert anti-obesity activity as well as remarkably direct effects, but MST may be potentially benefit for dietary cure and exercise-cure of obesity.

• 한국농공학회논문집
• /
• 제48권5호
• /
• pp.51-60
• /
• 2006

In order to examine the heat transfer characteristic of a soil warming system and effects of soil warming on the greenhouse heating load, control experiments were performed in two greenhouses covered with double polyethylene film. One treated the soil warming with an electric heat wire and the other treated a control. Inside and outside air temperature, soil temperature and heat flux, and heating energy consumption were measured under the set point of heating temperature of $5,\;10,\;15,\;and\;20^{\circ}C$, respectively. Soil temperatures in a soil warming treatment were observed $4.1\;to\;4.9^{\circ}C$ higher than a control. Heating energy consumptions decreased by 14.6 to 30.8% in a soil warming treatment. As the set point of heating temperature became lower, the rate of decrease in the heating energy consumptions increased. The percentage of soil heat flux in total heating load was -49.4 to 24.4% and as the set point of heating temperature became higher, the percentage increased. When the set point of heating temperature was low in a soil warming treatment, the soil heat flux load was minus value and it had an effect on reducing the heating load. Soil heat flux loads showed in proportion to the air temperature difference between the inside and outside of greenhouse but they showed big difference according to the soil warming treatment. So new model for estimation of the soil heat flux load should be introduced. Convective heat transfer coefficients were in proportion to the 1/3 power of temperature difference between the soil surface and the inside air. They were $3.41\;to\;12.42\;W/m^{2}^{\circ}C$ in their temperature difference of $0\;to\;10^{\circ}C$. Radiative heat loss from soil surface in greenhouse was about 66 to 130% of total heating load. To cut the radiation loss by the use of thermal curtains must be able to contribute for the energy saving in greenhouse.

• 대한설비공학회:학술대회논문집
• /
• 대한설비공학회 2008년도 하계학술발표대회 논문집
• /
• pp.517-522
• /
• 2008

Ventilation rate and filter were selected to simultaneously satisfy indoor air quality and minimize energy consumption in residential housing. The concentrations of indoor particles were calculated using an adapted mass balance model for various ventilation airflow rates. To satisfy the guidelines for indoor concentrations of particles, the minimum ventilation rates of 1.0/h, 0.6/h and 0.4/h were required for MERV11, MERV13 and MERV14, respectively. And the fan power consumptions induced by ducts, a heat exchanger and a filter were calculated for various ventilation airflow rates. The increase in the ventilation rate caused a dramatic increase in the power consumption, but the filter performance did not have much of an effect on the fan power for ventilation airflow rates lower than 0.4/h. The use of the ventilation filter of MERV 14 was suggested at a ventilation rate of 0.4/h when the fan power consumptions were considered in addition to the indoor concentrations of particles and $CO_2$. The use of the MERV14 filter at a ventilation rate of 0.6/h could be more effective than the additional use of an indoor air cleaner when the residential housing unit was ventilated.

• 한국태양에너지학회 논문집
• /
• 제34권1호
• /
• pp.39-47
• /
• 2014

Solar applications analysis and building energy performance depend on the quality of the solar resource data available. Unfortunately, most of the weather stations do not measure solar radiation data in Korea, as a reason many researchers have studied different solar radiation estimation models and suggested to apply them to various locations in Korea. In addition, they also studied the impact of hourly global solar radiation on energy performance of an office building by comparing the simulated building energy consumptions using four different weather files, one using measured, and three estimated solar radiation from different models, which are Cloud-cover Radiation Model (CRM), Zhang and Huang Model (ZHM), and Meteorological Radiation Model (MRM), and concluded that there was some impact on energy performance of the building due to the using different solar radiation models. However, the result cannot be applied to all other buildings since the simulated office building for that study only used limited building characteristics such as using fixed values of solar heat gain coefficient (SHGC) and window-to-wall ratio (WWR), which are significant parameters related to solar radiation that affect to the building energy consumptions. Therefore, there is a need to identify how the building energy consumption will be changed by varying these building parameters. In this study, the impact of one measured and three estimated global solar radiation on energy performance of the office building was conducted taking account of SHGC and WWR. As a result, it was identified that the impact of four different solar radiation data on energy performance of the office building was evident regardless SHGC and WWR changes, and concluded that the most suitable solar models was changed from the CRM/ZHM to the MRM as SHGC and WWR increases.

• 한국임상약학회지
• /
• 제24권2호
• /
• pp.126-134
• /
• 2014

Purpose: This study was aimed to examine the financial effect of 2-tiered copayment system on annual expenditure of pharmacy benefit in the National Health Insurance (NHI) of Korea, focusing on oral antidiabetic medications. Methods: 284 oral antidiabetic products with 14 different active single ingredients listed in the National Formulary of NHI (August 2009) were assigned to tier 1 or tier 2 according to the selected criteria. 10 different combinations of coinsurance rates were selected to estimate the changes in drug expenditure cost of NHI. Results: The annual drug cost was estimated based on the drug price per unit listed in the National Formulary and the used amount of products in 2009 from the IMS Health data of Korea. In the combinations of coinsurance rate of 20% for tier 1 and 40% for tier 2, the total annual drug cost was estimated to be reduced by 1.3% in the case of no change of generic and original drug consumptions, and to be reduced by 4.3% in the case of 10% increased generic drug consumptions. Conclusion: The tiered copayment system with optimal coinsurance rates appears to be a potential strategy to reduce the financial burden of NHI in Korea by promoting the use of generic products.

• 한국통신학회논문지
• /
• 제39C권11호
• /
• pp.1068-1077
• /
• 2014

본 논문은 무선 센서 네트워크 환경에서 센서노드의 에너지 소모를 최소화하기 위한 효과적인 모바일 싱크노드의 이동경로설정 방법을 제안한다. 싱크노드의 이동경로를 설정하기 위해 Random way point 방식을 사용한 기존의 연구들은 싱크노드의 위치와 경로를 파악하고 데이터 전송을 위한 라우팅 경로설정을 위해 불필요한 에너지 소모와 데이터 전송 지연을 발생시킬 수 있는 단점이 있다. 이를 해결하기 위해 제안하는 방법은 Hilbert curve를 사용하여 최적의 싱크노드 이동경로를 설정한다. 또한, 센서노드의 분포 밀도를 고려한 경로 수정을 통해 데이터 전송 지연을 최소화시킨다. 실험 결과 제안하는 기법은 기존의 TTDD, CBPER에 비해 최대 50배 이상의 에너지 효율을 보여주는 것으로 나타났다.

• 대한건축학회논문집:구조계
• /
• 제36권4호
• /
• pp.143-152
• /
• 2020

This study analyzes in detail greenhouse gas emissions in building sector. To this end, this study used data on building characteristics (including building type, region, and construction year) and monthly energy consumptions (including electricity, city gas, and district heat) for all buildings from 2015 to 2018. These data were collected from the National Building Energy Database and the energy consumptions were converted into greenhouse gas (GHG) emissions. The total amount of GHG emissions from the building sector has increased steadily from 2015 (118.1MtCO2eq.) to 2018 (132.6MtCO2eq.). On the other hand, the more recently constructed buildings had lower GHG intensities. This result shows that strengthening building design criteria was effective on the reduction of GHG emissions in buildings, and that the increased buildings contributed to increasing GHG emissions of the building sector. In addition, sales facilities are thought to have the largest reduction potential as they had the highest amount of GHG emissions and GHG intensity. This study is expected to help establish new policies for GHG reduction in building sector as well as to evaluate the effects of existing policies.