• Title/Summary/Keyword: complex resistance

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A Study on the Role of Maritime Enforcement Organization As Response of Illegal Fishing (불법어업에 대한 해상집행기관의 역할 및 방향 - 중국어선의 불법어업을 중심으로 -)

  • Jung, Bong-Kyu;Choi, Jung-Ho;Lim, Seok-Won
    • Journal of Fisheries and Marine Sciences Education
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    • v.26 no.4
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    • pp.769-788
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    • 2014
  • Today, all the countries of the world newly recognize importance of sea on 70% area of the earth, which are focused on efforts for security of marine territory and fishes resources. On the security concerns of the ocean & fishes resources, Sea are very important on the ground of the importance of the ocean, thus international community has been trying to combat a maritime security threat and illegal fisheries. Coastal states need to have proper state's jurisdiction and exercise it's jurisdiction to response effectively to a maritime security threat and illegal fisheries. Here, many of the coastal states strengthened the rights in Exclusive Economic Zone(;EEZ) naturally, there are made cooperation activities and keen competition in the sea because deepening of complex understanding of the relationship between the surrounding countries with marine surveys & continental shelf development, island territorial sovereignty & marine jurisdiction in overlap of sea area on EEZ. In these circumstances, foreign fishing boats invaded to our territorial waters and EEZ many times. in addition, Chinese fishing boats are going to illegal fisheries naturally. On this point, a powerful crackdown of maritime enforcement organization had no effect on them. Also more and more their resistance gathered strength and tendency of a illegal activities became systematization, group action and atrocity little by little. So this thesis includes a study on the regal regulation, the system and formalities on the control of illegal fishing. And the author analyzed the details of the activities of illegal fishing and boats controlled by Korea Coast Guard(KCG), fishing patrol vessels of Ministry of Maritime Affaires and Fisheries(MOMAF) and Navy etc. from in adjacent sea area of Korea. In relation to this, the policy and activity plan were devised to crackdown to illegal fisheries of foreign fishing boats and then it was enforced every year. According to this, analyze the present conditions of illegal fisheries of a foreign fishing boats on this study, also analyze the present conditions of maritime enforcement organization & found out problems to compared it. protect the territorial waters, at the same time protection of marine mineral resources & fishes resources of EEZ including continental shelf, which has want to study for the role & response of maritime enforcement organization for the protection of fisheries resources and a proper, a realistic confrontation plan of maritime enforcement organization against illegal fisheries of foreign fishing boats.

The Electrical Characteristics of the Grain Boundary in a $BaTiO_{3}$ PTC Thermistor ($BaTiO_{3}$ PTC 서미스터 입계의 전기적인 특성)

  • Kwon, Hyuk-Joo;Lee, Jae-Sung;Lee, Yong-Soo;Lee, Dong-Kee;Lee, Yong-Hyun
    • Journal of Sensor Science and Technology
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    • v.1 no.1
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    • pp.67-75
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    • 1992
  • PTC thermistor has been fabricated with as-received $BaTiO_{3}$ powder and its electrical properties were investigated. The resistivity of the PTC thermistor was measured at $20^{\circ}C$ intervals from $20^{\circ}C$ to $200^{\circ}C$. The electrical characteristics of the PTC thermistor are determined by the ac complex impedance analysis. The average grain size measured with a scanning electron microscope increased from $3.8{\mu}m$ to $8.8{\mu}m$ with increasing sintering temperature between $1280^{\circ}C$ and $1400^{\circ}C$. The maximum resistivity jump was $4{\times}10^{5}$. The bulk resistivity of the thermistor sintered above $1340^{\circ}C$ decreased with increasing temperature of the measurement. The grain boundary resistance increased exponentially, the grain boundary capacitance decreased, and the built-in potential at the grain boundary increased with increasing temperature of the measurement. The charge densiy at the grain boundary increased with increasing temperature up to $110^{\circ}C$, which leveled off with further increase in measuring temperature.

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AN EXPERIMENTAL STUDY OF EFFECT OF INTERMAXILLARY FIXATION AND OCCUSAL SPLINT ON PULMONARY FUNCTION (악간고정과 교합 상이 호흡기능에 미치는 영향에 관한 실험적 연구)

  • Lee, Joong-Kyou;Kim, Kyung-Wook;Lee, Jae-Hoon
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.28 no.3
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    • pp.175-181
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    • 2002
  • Intermaxillary fixation and occusal splint are routine procedure for maxillofacial fracture and orthognathic surgery. When these methods could obstruct oral airway the patients who kept intermaxillary fixation and occusal splint in their mouth, are very difficult to breath after surgery. Nasal bleeding and pharyngeal edema due to nasotracheal intubation, residual effect of muscle relaxants, and anesthetic agent could be contributing factor of airway obstruction. In this study, pulmonary function test was evaluated before and after intermaxillary fixation, and intermaxillary fixation with occusal splint in 22 volunteers. The results were as follows 1. FVC, %FVC, $FEV_1$, $FEV_1%$, PEF, $PEF_{50}$, MVV without intermaxillary fixtion were 4.45L, 88%, 4.03L, 90.9%, 10.26L/s, 5.53L/s, and 136.14L/min, and with intermaxillary fixation were 3.51L, 68.67%, 3.06L, 69.39L, 6.52L/s, 3.94L/s, and 69.39L/min. The results with intermaxillary fixation and occusal splint were 2.15L, 42.41%, 1.71L, 38.81%, 2.83L/s, 1.74L/s, and 37.14L/min. 2. Compared with before and after intermaxillary fixation, all values of pulmonary function test were decreased and after intermaxillary fixation and intermaixillary fixation with occulasal splint, the results were decreased. 3. MVV and PEF were decreased significantly with interaxillary fixtion and occusal splint, and FVC was less decreased. It meant that intermaxillary fixation and occluasal splint induced reduction of respiratory flow significantly, but less reduction of respiratory volume. 4. Intermaxillary fixation and occulsal splint induced increase of airway resistance, decrease of expiratory volume and air flow. So severe respiratory difficulty could be seen to all volunteers who kept intermaxillary fixtion and occusal splint. 5. In classification of respiratory difficulty, intermaxillary fixation with occulsal splint induced complex respiratory difficulty more than intermaxillary fixation only did. From the above results, doctors who care patients kept intermaxillary fixation and occusal splint should be aware of respiratory depression caused by these treatment.

The antimicrobial activity of Hwangheuk-san and synergy effect with oxacillin against methicillin-resistant Staphylococcus aureus (황흑산(黃黑散)의 메티실린 내성 황색포도상구균에 대한 항균 활성과 옥사실린과의 시너지 효과)

  • Choi, Sung-Hoon;Kang, Ok-Hua;Zhou, Tian;Kong, Ryong;Lee, Seung-Jin;Kang, Dam-Hee;Jung, Hye-In;Lee, Young-Seob;Kwon, Dong-Yeul
    • The Korea Journal of Herbology
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    • v.31 no.5
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    • pp.93-98
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    • 2016
  • Objectives : Hwangheuk-san is a complex prescription composed of oriental traditional medicine and has been reported for antioxidant, antimicrobial and anticancer effects in the recent study. Methicillin-resistant Staphylococcus aureus (MRSA) is one of important causes of fatal infectious diseases such as septicemia, endocarditis, toxic shock syndrome, pneumonia, skin and soft tissue infections (SSTIs). S. aureus is reported as being for a variety of human diseases and its epidemiological relevance is mainly due to their ability of becoming highly resistant to common antimicrobials such as tetracycline, penicillin, cphalosporin and aminoglycoside. The objective of this study is to determine the antimicrobial effect of Hwangheuk-san ethanol extracts (HHS) and synergistic effects with antibiotics oxacillin against MRSA.Methods : The antimicrobial activity of HHS was measured by the disc diffusion method, broth microdilution method and the checkerboard dilution test, time-kill curve assay was performed to investigate synergistic effects with antibiotics oxacillin against MRSA.Results : HHS showed antimicrobial activity against MRSA with a MIC value of 125 ㎍/㎖. In the checkerboard test, the interaction of HHS with antibiotics oxacillin produced almost synergy or partial synergy against MRSA. This study showed that HHS reduced the MICs of oxacillin tested, and a remarkable antibacterial effect of HHS, with membrane permeability enhancers.Conclusions : These results suggest that HHS has the antimicrobial effect and synergistic effects with antibiotics oxacillin against MRSA. This study thus can be a valuable source for the development of a new drug with low MRSA resistance.

Phenotypic Suppression of Rad53 Mutation by CYC8 (CYC8에 의한 rad53 돌연변이의 표현형 억제에 대한 연구)

  • Park, Kyoung-Jun;Choi, Do-Hee;Kwon, Sung-Hun;Kim, Joon-Ho;Bae, Sung-Ho
    • Korean Journal of Microbiology
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    • v.46 no.2
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    • pp.122-126
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    • 2010
  • RAD53 functions as an effector kinase of checkpoint pathways in Saccharomyces cerevisiae, which plays a central role to regulate many downstream cellular processes in response to DNA damage. It also involves in transcriptional activation of various genes including RNR genes which encode the key enzyme required for dNTP synthesis. In this study, we identified CYC8 as a suppressor for the hydroxyurea sensitivity of $rad53{\Delta}$ mutation. $Rad53{\Delta}$ mutant transformed with a multi-copy plasmid containing CYC8 showed increased hydroxyurea resistance. In contrast, TUP1 which forms a complex with CYC8 did not function as a suppressor. In the case of mutations, both $cyc8{\Delta}$ and $tup1{\Delta}$ suppressed hydroxyurea sensitivity of $rad53{\Delta}$. Since CYC8 can propagate as a prion in yeast, overexpression of CYC8 induced misfolding of the normal CYC8 proteins, resulting in dominant cyc8-phenotype. Therefore, it is suggested that CYC8 can act as a multi-copy suppressor due to its prion property. It was observed that the levels of RNR transcription were increased in the yeast strains containing either multi-copies of CYC8 gene or $cyc8{\Delta}$ mutation, suggesting that the increased level of RNR will elevate the intracellular pools of dNTPs, which, in turn, suppress the phenotype of $rad53{\Delta}$ mutation.

Isolation and Antimicrobial Susceptibility of Campylobacter jejuni from Diarrhea Patients (설사환자에서 Campylobacter jejuni의 분리 및 항생제 감수성 특성)

  • Park, Eun-Hee;Kim, Joung-A;Choi, Seung-Hwa;Bin, Jae-Hun;Cheigh, Hong-Sik;Suk, Dong-Hee;Lee, Su-Chul;Kim, Young-Hui
    • Journal of Life Science
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    • v.17 no.6 s.86
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    • pp.811-815
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    • 2007
  • ln this study we isolated 27 isolates of Campylobacter jejuni from stool samples of 882 diarrheal patients. The seasonal distribution of patients was highest at July (11.7%). All the isolates of C. jejuni hydrolyzing sodium hippurate were serotyped on basis of heat-stable antigens, and identified with the use of passive hemagglutination assay. A total of 59.3% among 27 C. jejuni isolates were identified into 6 different serotypes, which serotype HS2, HSl/44, and HS2l were dominant. Antibiotics resistant rates of C. jejuni isolates were shown to be 100%, 63.0%, 51.9%, 37.0%, 33.3%, 25.9% and 7.4% to cephalothin, trimethoprim- sulfamethoxazole, tetracycline, ciprofloxacin, ampicillin, gentamycin and clindamycin, respectively. All isolates were sensitive to the erythromycin and imipenem.

Diagnostic Evaluation of Non-Interpretable Results Associated with rpoB Gene in Genotype MTBDRplus Ver 2.0

  • Singh, Binit Kumar;Sharma, Rohini;Kodan, Parul;Soneja, Manish;Jorwal, Pankaj;Nischal, Neeraj;Biswas, Ashutosh;Sarin, Sanjay;Ramachandran, Ranjani;Wig, Naveet
    • Tuberculosis and Respiratory Diseases
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    • v.83 no.4
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    • pp.289-294
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    • 2020
  • Background: Line probe assay (LPA) is standard diagnostic tool to detect multidrug resistant tuberculosis. Non-interpretable (NI) results in LPA (complete missing or light wild-type 3 and 8 bands with no mutation band in rpoB gene region) poses a diagnostic challenge. Methods: Sputum samples obtained between October 2016 and July 2017 at the Intermediate Reference Laboratory, All India Institute of Medical Sciences Hospital, New Delhi, India were screened. Smear-positive and smear-negative culture-positive specimens were subjected to LPA Genotype MTBDRplus Ver 2.0. Smear-negative with culture-negative and culture contamination were excluded. LPA NI samples were subjected to phenotypic drug susceptibility testing (pDST) using MGIT-960 and sequencing. Results: A total of 1,614 sputum specimens were screened and 1,340 were included for the study (smear-positive [n=1,188] and smear-negative culture-positive [n=152]). LPA demonstrated 1,306 (97.5%) valid results with TUB (Mycobacterium tuberculosis) band, 24 (1.8%) NI, three (0.2%) valid results without TUB band, and seven (0.5%) invalid results. Among the NI results, 22 isolates (91.7%) were found to be rifampicin (RIF) resistant and two (8.3%) were RIF sensitive in the pDST. Sequencing revealed that rpoB mutations were noted in all 22 cases with RIF resistance, whereas the remaining two cases had wild-type strains. Of the 22 cases with rpoB mutations, the most frequent mutation was S531W (n=10, 45.5%), followed by S531F (n=6, 27.2%), L530P (n=2, 9.1%), A532V (n=2, 9.1%), and L533P (n=2, 9.1%). Conclusion: The present study showed that the results of the Genotype MTBDRplus assay were NI in a small proportion of isolates. pDST and rpoB sequencing were useful in elucidating the cause and clinical meaning of the NI results.

A Review and Analysis of the Thermal Exposure in Large Compartment Fire Experiments

  • Gupta, Vinny;Hidalgo, Juan P.;Lange, David;Cowlard, Adam;Abecassis-Empis, Cecilia;Torero, Jose L.
    • International Journal of High-Rise Buildings
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    • v.10 no.4
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    • pp.345-364
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    • 2021
  • Developments in the understanding of fire behaviour for large open-plan spaces typical of tall buildings have been greatly outpaced by the rate at which these buildings are being constructed and their characteristics changed. Numerous high-profile fire-induced failures have highlighted the inadequacy of existing tools and standards for fire engineering when applied to highly-optimised modern tall buildings. With the continued increase in height and complexity of tall buildings, the risk to the occupants from fire-induced structural collapse increases, thus understanding the performance of complex structural systems under fire exposure is imperative. Therefore, an accurate representation of the design fire for open-plan compartments is required for the purposes of design. This will allow for knowledge-driven, quantifiable factors of safety to be used in the design of highly optimised modern tall buildings. In this paper, we review the state-of-the-art experimental research on large open-plan compartment fires from the past three decades. We have assimilated results collected from 37 large-scale compartment fire experiments of the open-plan type conducted from 1993 to 2019, covering a range of compartment and fuel characteristics. Spatial and temporal distributions of the heat fluxes imposed on compartment ceilings are estimated from the data. The complexity of the compartment fire dynamics is highlighted by the large differences in the data collected, which currently complicates the development of engineering tools based on physical models. Despite the large variability, this analysis shows that the orders of magnitude of the thermal exposure are defined by the ratio of flame spread and burnout front velocities (VS / VBO), which enables the grouping of open-plan compartment fires into three distinct modes of fire spread. Each mode is found to exhibit a characteristic order of magnitude and temporal distribution of thermal exposure. The results show that the magnitude of the thermal exposure for each mode are not consistent with existing performance-based design models, nevertheless, our analysis offers a new pathway for defining thermal exposure from realistic fire scenarios in large open-plan compartments.

A study on the controversy of the modernity of the Tsukiji Little Theater -With a focus on Kabuki, Shinpa, and Shingeki- (축지소극장의 근대성 문제에 대한 연구 -가부키(歌舞伎), 신파(新派), 신극(新劇)의 연관성-)

  • Kim, Hyeoncheol
    • Journal of Korean Theatre Studies Association
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    • no.48
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    • pp.421-446
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    • 2012
  • The purpose of this paper is to shed light onto the historical significance and limitations of the Tsukiji Little Theater's modern performances. The Tsukiji Little Theater holds a position of great importance to the history of both Japanese and Korean modern theater. Some, however, are under the completely opposite impression. There are also mixed opinions about whether the Tsukiji Little Theater is a "model example" of the modern theatrical movement or a "bad example". Based on this controversy, we look into the definitive characteristics of the Tsukiji Little Theater based mostly on "the controversy over translated foreign plays", "the controversy of foreign plays versus original plays", "the value of kabuki" and "Shinpa as a rival". This paper looked into the differences in controversy over translated foreign plays in the Tsukiji Little Theater and the controversy in existing translated foreign plays. It mostly looks at the "casuistry of foreign plays" and the "cultural engineering theory of foreign plays"to get a grasp on the controversy surrounding existing translated foreign plays. Meanwhile, the "internally critical meaning" towards the original plays of renowned writers was strong in the controversy of foreign plays in the Tsukiji Little Theater. Kaoru Osanai defined the 1920s as a dark period, and persisted that because of the activity of the Shingeki movement, foreign plays were needed instead of low-level original plays. This study examines the characteristics of original plays and foreign plays publicly performed at the Tsukiji Little Theater to analyze the "controversy of translated foreign plays versus original plays". The Tsukiji Little Theater mostly put on shows with a strong sense of resistance or that defied the old times. This caused there to be a lot of emphasis put on the rebellious mindset towards old conventions and ideologies for most of the plays, both foreign and original, and the problem arises that little mind was paid to the integrity or beauty of the works. In looking at the "value of kabuki", this paper looked into Kaoru Osanai, who was deeply involved in kabuki actors. He evaluated traditional Japanese arts highly not because of the literary value of their scripts, but because he recognized the value of how they were performed. In order to create a new spectacle, music, dance and mime was taken in from countries around the world, and kabuki was regarded highly as a means of expression on stage. Finally, we also examine the recognized reasons for treating Shinpa as a rival. There is a relationship between these reasons and a complex about the audiences they drew. The Shinpa performances always had many spectators and were successful, but those at the Tsukiji Little Theater were so unpopular with the public that it was hard for them to financially run their theater group. The empty seats in their theater constantly made the modern intellectuals in the Shingeki movement feel inferior.

Development of embedded type antenna structure with NFC and WPC complex function (NFC 와 WPC 복합기능의 삽입형 안테나 복합체 개발)

  • Park, Rog-gook;Lee, Deok-soo;Jang, Jeong-sun
    • Journal of Platform Technology
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    • v.6 no.4
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    • pp.59-68
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    • 2018
  • The objective of this study is to develop an embedded antenna structure with NFC and WPC composite functions. By selecting stable materials, the optimal component ratio of the polymer sheet was determined. The low cost embedded winding method compared to the existing FPCB was devised. During the winding process, characterization and process technology were developed. We also fabricated a ferrite mold to process the WPC grooves and developed the process technology for optimizing the WPC antenna. The following conclusions were obtained. (1) Optimum composition ratio was derived as Fe 87.5%, Si 7%, Al 5.5% and selected as the final material. (2) Optimal sheet conditions were derived from the experimental evaluation method and the experimental design method through the combination test of the optimized sheet and the conventional mass production FPCB. (3) According to coil diameter and inner diameter, Q value fluctuation, resistance value and efficiency fluctuation are obtained. Therefore, the most suitable coil condition is selected and Rx matching is performed. (4) The EMV load modulation test and the cognitive distance test of the polymer sheet and the ferrite sheet showed that the recognition distance of the polymer sheet at 1k and 4K was 32-33 mm and the recognition distance of the ferrite sheet at the same condition was 30-31 mm.