• Title/Summary/Keyword: comparison of efficacy

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Tooth whitening maintenance efficacy of dentifrices containing several active ingredients in vitro and in vivo (유효성분들을 배합한 치약제의 실험실적 및 임상적 치아미백유지 효과)

  • Ahn, Jae-Hyun;Kim, Ji-Hye;Kim, Jong-Hoon
    • Journal of Korean society of Dental Hygiene
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    • v.15 no.2
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    • pp.325-332
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    • 2015
  • Objectives: The purpose of this study was to investigate tooth whitening maintenance efficacy of several dentifrices containing effective ingredients for tooth whitening. Methods: Hydroxyapatite specimens(HAPs) staining was done by using modified Stookey's methods. HAPs were treated with 2.9% hydrogen peroxide containing strip for whitening, and were shaken with several dentifrice slurry(dentifrice 1 : artificial saliva 2) for 30 minutes. The HAPs were finally dipped in staining solution for an hour. Shaking and dipping were repeated 4 times and lightness values were measured by colorimeter at each step. In clinical test, test 4 dentifrice and control dentifrice were evaluated by 21 subjects for 2 months after receiving institutional review board(IRB) approval. Organoleptic(vita shade guide) and instrumental(SHADEEYE-NCC) evaluation were performed for whiteness change of teeth. Statistical analysis was performed using repeated measures ANOVA, Tukey's post hoc test and ${\chi}^2$-test(p<0.05). Results: All dentifrices showed statistical significance in comparison with control dentifrice containing sodium fluoride and test 4 dentifrice containing sodium pyrophosphate, sodium metaphosphate, candelilla wax, and sodium fluoride showed statistical significance in comparison with other dentifrices by inhibiting staining in vitro(p<0.05). In clinical test, test 4 dentifrice showed better effects than control dentifrice in organoleptic and instrumental evaluation in tooth whitening maintenance efficacy(p<0.05). The awareness toward tooth whitening maintenance efficacy for 2 months use showed that test 4 dentifrice was much better than control dentifrice, but did not show statistically significant(p>0.05). Conclusions: Dentifrice containing sodium pyrophosphate, sodium metaphosphate, candelilla wax and sodium fluoride was more effective in keeping teeth white.

Effects of Cynanchi Wilfordii Radix on Prevention of Hyperlipidemia and Liver Damage Induced by Alcohol (백수오(白首烏)가 알콜 투여로 유발된 흰쥐의 고지혈증과 간 손상의 예방에 미치는 영향)

  • Seo, Bu-Il
    • The Korea Journal of Herbology
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    • v.23 no.4
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    • pp.31-38
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    • 2008
  • Objectives: This study was performed to investigate the effects of water extract from Cynanchi Wilfordii Radix on prevention of hyperlipidemia and liver damage induced by alcohol. Methods: Except for the normal group, we fed rat on 25% alcohol for 55 days. And water extracts from Cynanchi Wilfordii Radix were administrated for the Cynanchi Wilfordii Radix group during the same period. We measured the serum components in rat's blood, body weight and weight of liver. Results: At first, we observed effects of Cynanchi Wilfordii Radix on prevention of hyperlipidemia induced by alcohol. Cynanchi Wilfordii Radix group showed significant decrease of total cholesterol and triglyceride in comparison with those of the control group. Cynanchi Wilfordii Radix group showed significant increase of HDL-cholesterol in comparison with those of the control group. Cynanchi Wilfordii Radix group showed significant increase of body weight in comparison with those of the control group in 4weeks and 8weeks. At second, we observed effects of Cynanchi Wilfordii Radix on prevention of liver damage induced by alcohol. Cynanchi Wilfordii Radix group showed significant decrease of GPT and ALP in comparison with those of the control group. Cynanchi Wilfordii Radix group showed significant increase of liver weight in comparison with those of the control group. Conclusions: Reviewing these experimental results, it appears that water extracts from Cynanchi Wilfordii Radix have pharmaceutical efficacy on prevention of hyperlipidemia and liver damage induced by alcohol. Therefore further additional study should be conducted to elucidate in depth the pharmaceutical efficacy of these.

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Effects of Saengkankeonbi-tang on Prevention of Hyperlipidemia and Liver Damage Induced by Alcohol (생간건비탕(生肝健脾湯)이 알코올 투여로 유발된 흰쥐의 고지혈증과 간 손상의 예방에 미치는 영향)

  • Hwang, Soo-Jin;Choi, Hong-Sik;Kim, Seung-Mo;Woo, Chang-Hoon
    • The Korea Journal of Herbology
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    • v.24 no.4
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    • pp.9-16
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    • 2009
  • Objectives : This study was performed to investigate the effect of water extracts from Saengkankeonbi-tang on prevention of hyperlipidemia and liver damage induced by alcohol. Methods : Except for the normal group, we fed rats the control and Saengkankeonbi-tang groups with 25% alcohol for 55 days. For the same period we fed the Saengkankeonbi-tang group with Saengkankeonbi-tang extract as well and rats in normal and contrlo group on saline solution. We measured the serum components in rat's blood, body weight and weight of liver. Results : 1. At first, we observed effects of Saengkankeonbi-tang on prevention of hyperlipemia induced by alcohol. Saengkankeonbi-tang group showed significant decrease in total cholesterol levels in comparison with those of the control group. Saengkankeonbi-tang group showed significant increase in HDL-cholesterol levels in comparison with those of the control group. Saengkankeonbi-tang group showed significant increase of body weight in comparison with those of the control group in 4weeks and 8weeks. 2. At second, we observed effects of Saengkankeonbi-tang on prevention of liver damage induced by alcohol. Saengkankeonbi-tang group showed significant decrease in GOT, GPT, LDH and ALP levels in comparison with those of the control group. Saengkankeonbi-tang group showed significant increase of liver weight in comparison with those of the control group. Conclusions : Reviewing these experimental results, it appears that water extracts from Saengkankeonbi-tang have pharmaceutical efficacy on prevention of hyperlipidemia and liver damage induced by alcohol. Therefore further additional study should be conducted to elucidate in depth the pharmaceutical efficacy of these.

Effect of Polygoni Multiflori Radix and Polygoni Multiflori Radix Preparat On Prevention of Osteoporosis In Ovariectomized Rats (생하수오(生何首烏)와 제하수오(製何首烏)가 난소적출(卵巢摘出)로 유발된 흰쥐의 골다공증(骨多孔症) 예방효과에 미치는 영향)

  • Seo, Bu-Il;Park, Ji-Ha;Lee, Eun-Sook;Choi, Do-Jeom;Choi, Hong-sik;Kim, Ho-Kyoung;Seo, Young-Bae;Kim, In-Rak;Park, Jin-Hee;Seo, Gyoo-Tae
    • The Korea Journal of Herbology
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    • v.20 no.2
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    • pp.137-148
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    • 2005
  • Objectives : The present study has been undertaken to investigate the effects of Polygoni Multiflori Radix and Polygoni Multiflori Radix Preparat on prevention of osteoporosis in ovariectomized rats. Method : In this experiment, the rats were ovariectomized. Rats were administered by 2 kinds of medicine, Polygoni Multiflori Radix and Polygoni Multiflori Radix Preparat. Results : The levels of spinal bone mineral density was significantly increased in comparison with OVX group at 6 weeks in Polygoni Multiflori Radix Preparat group. The levels of serum osteoclacin and calcium didn't show significant changes in comparison with OVX group in Polygoni Multiflori Radix and Polygoni Multiflori Radix Preparat group. The levels of serum ALP showed significant decrease in comparison with OVX group at 3 weeks in Polygoni Multiflori Radix group, and showed significant decrease in comparison with OVX group at 6 weeks in Polygoni Multiflori Radix Preparat group. The levels of serum phosphorus showed significant decrease in comparison with OVX group at 3, 6 weeks in Polygoni Multiflori Radix, and showed significant decrease in comparison with OVX group at 6 weeks in Polygoni Multiflori Radix Preparat group. The levels of urine calcium and phosphorus didn't show significant changes in comparison with OVX group in Polygoni Multiflori Radix and Polygoni Multiflori Radix Preparat group. The levels of femoral and fibula-tibial calcium showed significant increase in comparison with OVX group in Polygoni Multiflori Radix and Polygoni Multiflori Radix Preparat group. The levels of femoral phosphorus showed significant increase in comparison with OVX group in Polygoni Multiflori Radix and Polygoni Multiflori Radix Preparat group. The levels of femoral and fibula-tibial ash weight showed significant increase in comparison with OVX group in Polygoni Multiflori Radix Preparat group. And the levels of fibula-tibial ash weight showed significant increase in comparison with OVX group in Polygoni Multiflori Radix group. The levels of body weight and uterus weight didn't show significant changes in comparison with OVX group in Polygoni Multiflon Radix and Polygoni Multiflori Radix Preparat group. Conclusion : Reviewing these experimetal results, it appears that Polygoni Multiflori Radix and Polygoni Multiflori Radix Preparat have efficacy on prevention of osteoporosis. In particular Polygoni Multiflori Radix Preparat showed good efficacy in comparison with Polygoni Multiflori Radix Preparat.

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Differences in The Effects of Core Nursing Skills Education According to the Use of Peer-Assisted Learning (PAL) Among Nursing Students

  • Lee, Mi-Young;Kim, Bo-Yeoul
    • International Journal of Contents
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    • v.15 no.3
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    • pp.39-46
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    • 2019
  • This study aimed to develop a peer-assisted learning (PAL) program for use in a core nursing skills education course and to investigate the effects of the education program on three key outcomes. A comparative study was conducted through the division of students of a core nursing skills education program into a treatment group and control group. After the programs, self-efficacy, confidence and satisfaction were compared between the groups. The comparison of these three factors indicated that the related scores were significantly higher in the treatment group receiving the education program with the PAL method than those of the control group receiving traditional education. We concluded that self-efficacy gave the nursing students the confidence that they could successfully perform their tasks and motivation to learn. Education programs using the PAL method are suggested as an effective method for the acquisition of skills among nursing students.

Preventive effects of Saponariae Vaccariae Semen and Melandryi Firmi Herba on hyperlipidemia and liver damage induced by alcohol (왕부류행(王不留行)과 경엽여루채(硬葉女婁菜)가 알콜 투여로 유발된 흰쥐의 고지혈증과 간 손상의 예방에 미치는 영향)

  • Choi, Jae-Young;Seo, Bu-Il;Oh, Dal-Seok;Park, Ji-Ha;Roh, Seong-Soo
    • The Korea Journal of Herbology
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    • v.27 no.1
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    • pp.27-34
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    • 2012
  • Objectives : This study was performed to compare the preventive effect of water extracts from Saponariae Vaccariae Semen(SVS) and Melandryi Firmi Herba(MFH) on hyperlipidemia and liver damage induced by alcohol. Methods : Except for the normal group, I fed rat on 25% alcohol for 55 days. And each extract was administrated for the same period. I measured the serum component in rat's blood, body weight and weight of liver. Results : At first, I observed effects of SVS and MFH on hyperlipidemia induced by alcohol. SVS and MFH group didn't show the significant decrease of total cholesterol in comparison with those of the control group. SVS and MFH group showed the significant increase of HDL-cholesterol in comparison with those of the control group. SVS group showed the significant decrease of triglyceride in comparison with those of the control group, but MFH group didn't show the significant decrease of triglyceride in comparison with those of the control group. SVS group showed the significant increase of body weight in comparison with those of the control group at 4weeks and 8weeks. But, MFH group didn't show the significant changes of body weight in comparison with those of the control group at 4weeks and 8weeks. By the way, SVS group showed the significant decrease of triglyceride in comparison with those of MFH group. SVS group showed the significant increase of body weight in comparison with those of MFH group at 8weeks. At second, I observed effects of SVS and MFH on liver damage induced by alcohol. SVS and MFH group showed the significant decrease of AST(aspartate aminotransferase), ALT(alanine aminotransferase), ALP(alkaline phosphatase) and LDH(lactate dehydrogenase) in comparison with those of the control group. SVS group showed the significant increase of liver weight in comparison with those of the control group, but MFH group didn't show the significant increase of liver weight in comparison with those of the control group. By the way, SVS group showed the significant increase of liver weight in comparison with those of MFH group. Conclusions : Reviewing these experimental results, it suggests that water extracts from SVS and MFH have pharmaceutical preventive efficacy on hyperlipidemia and liver damage induced by alcohol. Therefore further additional study should be conducted to elucidate the pharmaceutical efficacy of these in depth.

Comparison study acupuncture treatment with Acupuncture & Moxibustion combined treatment for frozen shoulder patients (오십견 환자의 침 치료군과 뜸 병용치료군 간의 임상적 비교 고찰)

  • Kim, Young-Il
    • Journal of Haehwa Medicine
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    • v.15 no.2
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    • pp.1-7
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    • 2006
  • Objectives : Comparison acupuncture treatment with Acupuncture & Moxibustion combined treatment for frozen shoulder 20 case patients Methods : Efficacy evaluation using Apley scratch test(ROM), Martin.A.N'Improvement rate Results : 1. Acupuncture & Moxibustion combined treatment group were better than acupuncture treatment group in Martin.A.N' Improvement rate. 2. Acupuncture & Moxibustion combined treatment group were better than acupuncture treatment group in Apley scratch test(ROM). but this study need to many case frozen shoulder investigation.

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Cognitive Behavioral Therapy for Improving Parenting Efficacy of Married Immigrant Women (결혼이주여성의 양육효능감 향상을 위한 CBT 부모훈련 프로그램의 개발 및 효과)

  • Kim, Hee Jung;Kim, Jung Min
    • Journal of Families and Better Life
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    • v.33 no.2
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    • pp.135-148
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    • 2015
  • The purpose of this study is to develop cognitive behavioral therapy(CBT) to improve the parenting efficacy of married immigrant women, and verify its effectiveness. In the CBT of this study, behavioral technique was added to cognitive reconstruction based on cultural context in order to improve parenting efficacy. The study selected 28 married immigrant women, and randomly divided them into a CBT group(10), a general treatment group(8) and a control group(10). The CBT and the general treatment programs consisted of 10 sessions, approximately 2 hours in duration. The results of the study were as follows. 1) The level of parenting efficacy was improved significantly in the CBT and the general treatment group. 2) The level of negative automatic thoughts and dysfunctional parenting thoughts was significantly decreased only in the CBT group. 3) In the CBT and the general treatment group, the level of parenting stress and acculturative stress was decreased while the level of psychological well-being improved. On the other hand, the level of parent-adolescent communication was improved significantly only in the CBT group. 4) In comparison with the general treatment group, the CBT group showed higher parenting efficacy and lower automatic thoughts and dysfunctional parenting thoughts. This study has significance in its attempt to develop a parent training program to improve the parenting efficacy of married immigrant women by integrating behavioral modification and communication skills training focused on cognitive reconstruction of parenting-related negative thoughts and beliefs in application of the CBT paradigm.

The Effect of Dual Task Training based on the International Classification of Functioning, Disability, and Health on Walking Ability and Self-Efficacy in Chronic Stroke (ICF 구성요소 기반 이중과제 훈련이 만성 뇌졸중 환자의 보행 능력과 자기효능감에 미치는 영향)

  • Lee, Jeong-A;Lee, Hyun-Min
    • Journal of the Korean Society of Physical Medicine
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    • v.12 no.1
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    • pp.121-129
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    • 2017
  • PURPOSE: This study was conducted to determine the effect of dual-task training (based on the International Classification of Functioning, Disability, and Health; ICF) on walking ability and self-efficacy in individuals with chronic stroke. METHODS: 22 chronic stroke patients participated in this study. Participants were randomly allocated into either the single-task group (n=11) or the dual-task group (n=11). Both groups had physical training three a week for 4 weeks, and at a three-week follow-up. Outcome measures included the 10m walking test (10MWT), figure of 8 walk test (F8WT), dynamic gait index (DGI), and Self-efficacy scale. All data were analyzed using SPSS 18.0 for Windows. Between-group and within-group comparison were analyzed by using the Mann-Whitney U test and Wilcoxon singed-rank test respectively. RESULTS: In the dual-task group, the 10MWT, time and steps of F8WT, DGI, and self-efficacy showed significant differences between pre- and post-test (p<.05). The Changes between the pre- and post-test values of 10MWT (p<.05), DGI (p<.05), and self-efficacy scale (p<.05) showed significant differences between the dual-task group and single-task group. CONCLUSION: Participants reported improved walking ability and self-efficacy, suggesting that dual-task training holds promise in the rehabilitation of walking in chronic stroke patients. This study showed that ICF-based on a dual-task protocol contiributes to motor learning after chronic stroke.

Gender Differences in Stress Levels and Coping Strategies in South Korea While Using Mobile Phones

  • Jun, Sangmin;Yeo, Jungsung
    • International Journal of Human Ecology
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    • v.14 no.1
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    • pp.1-12
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    • 2013
  • This article examines gender differences in stress levels and coping strategies while using mobile phones. We constructed an e-mail survey to collect data from 1,000 adults in South Korea, and used latent means comparison and multi-group structural regression in structural equation modeling. It was determined that as compared to men, women were more vulnerable to stress. Regarding coping, women used all three coping strategies more equally than men, including active coping, expressive support seeking, and avoidance, whereas men mainly chose active coping; however, there were no significant gender differences in coping outcomes, and both women and men coped effectively by choosing their own personal strategies. We suggested how to reduce stress levels for women through enhancing their self-efficacy, as self-efficacy was shown to reduce stress levels specifically for women. Additionally, based on our findings, we proposed how both men and women could cope more effectively.