• Korean Journal of Animal Reproduction
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• v.9 no.1
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• pp.66-71
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• 1985

After the induction of estrus by the PGFF2$\alpha$-GTH combination on the 118 repeat breeder cow during of 6-13 days of the estrus cycle, the effects of GTH, antibiotics, antibiotics-GTH combination were compared. The results of this study, the following conclusion were obtained: 1. The rate of estrus was reduced the administration of GTH before the administration of PGF2$\alpha$. 2. The rate of ovulation delayed was 24.6% in the group with the administration GTH, but 34.1% without the administration GTH. Duration of ovulation was shortened by GTH. 3. The impregnation induction by the administration of PGF2$\alpha$, PGF2$\alpha$-antibiotics, PGF2$\alpha$-GTH-antibiotics were 41.7%, 69.5%, 55.6% and 80.8% respectively injection in the uterus was more effective than the administration. Before or after the A.I., the above combination was most effective. 4. In antibiotics sensitivity test in vitro of the intravagina bacteria, 5.0%, 12.7% and 60.0% of bacteria were sensitive to Penicilline, Streptomycin and Gentamicin respectively.

• Journal of Industrial Technology
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• v.14
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• pp.101-107
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• 1994

This study is to investigate harbor oscillation phenomenon according to combination of the wall structures by model experiment in a three dimensional wave basin. Six different types of wall combination were chosen through combination of erect wall, erect dissipation block, and sand beach, wave height at selected points in the harbor were measured by electronic wave gage. Test results show that the wall structure composed solely of erect walls showed generally highest harbor oscillation. Since natural beach shows lower reflection than erect dissipation block do, we thought it would be more efficient to use natural beach for improved harbor oscillation. The result showed, however, that the erect dissipation block are more efficient than natural beach to attain less harbor oscillation. The reason seens that the erect dissipation blocks have better capability to control breaking wave on the surface of the structure.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.23 no.11
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• pp.957-965
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• 2013

This paper deals with analytical methods for low frequency and high frequency brake squeal noise on brake-rear caliper. In order to improve low frequency and high frequency squeal noise, we take survey caliper bracket shape parameters and housing shape parameters. Besides, using the combination of bracket and housing parameter were surveyed. Thus, using the combination of bracket Alt_05 and housing Alt_45 specifications, instability analysis and brake dynamo test were carried out. Based upon the two models, low and high frequency squeal noise of base model were improved. But, for 6.0 kHz frequency noise, which is not improved, it needs to additionally study on instability analysis and combination of the other brake components.

• Tuberculosis and Respiratory Diseases
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• v.47 no.6
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• pp.757-767
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• 1999

Background: Diagnosis by smear and/or cultures of the Mycobacterium tuberculosis from body fluid or biopsy specimen is "Gold standard". However the sensitivity of the direct microscopy is relatively low and culture of mycobacteria is time consuming. Despite an explosion in the techniques of rapid identification of mycobacteria by molecular genetic means, it is laborious and expensive and then rapid, inexpensive serodiagnosis is interested in diagnosis of tuberculosis. But sensitivity and specificity of known serologic antigen is not full sufficient level and then new antigen develop and combination cocktails of new developed antigens by ELISA are needed. Method: To compare the efficacy of different mycobacterial specific antigen and to assess the applicability of the combination of several different antigens in the diagnosis of tuberculosis, five ELISA tests derived 14KDa, 16KDa, 19KDa, 23KDa, 38KDa were evaluated in 57 active pulmonary patient and 24 inactive post-therapy follow up patient and 48 normal control. Results: The optical densities of ELISA test with 14KDa, 16KDa, 19KDa, 23KDa, 38KDa were significantly higher in active tuberculosis cases than in normal control(P<0.001, P<0.001, P<0.027, P<0.001, P<0.001) and those with 16KDa, 38KDa were significant higher in active tuberculosis cases than in inactive post-therapy follow up cases(P<0.01. P<0.001) and those of 14KDa, 16KDa, 23KDa, 38KDa were significant higher in inactive post-therapy follow up cases than in normal control(P<0.008. P<0.01. P<0.006. P<0.001). The sensitivity of 14KDa, 16KDa, 19KDa, 23KDa, 38KDa in active pulmonary patient cases was 42.1%, 43.9%, 15.8%, 28.0%, 70.2%, respectively and the specificity of 14KDa, 16KDa, 19KDa, 23KDa, 38KDa in active pulmonary patient cases was 95.8%, 95.8%, 91.7%, 89.6%, 93.8%, respectively. The sensitivity and specificity of combination 38KDa with 16KDa was 87% and 93.7%. Conclusion: The sensitivity and specificity of new antigens for serodiagnosis of the tuberculosis still remains limited at around 70%, which makes its a poor diagnostic tool for disease confirmation. A combination of cocktail antigens provided by cut-off value adjustment for serodiagnosis of tuberculosis some improved diagnostic yield than single antigen serologic test.

• Journal of the Korean Society of Clothing and Textiles
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• v.25 no.3
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• pp.525-536
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• 2001

The purpose of this study is to evaluate the combination of suit details through visual evaluation which helps compensating middle aged womens body defects for their more attractive fashion styles. In this study, styles of the evaluated suits are formal and classical. The designs of evaluated suits are manipulated in 40 different kinds by the essential elements such as collars, necklines(tailored collars, soutien collars, stand collars, round necklines, V-necklines), bottoms(slacks, skirts), pocket(flap pocket, none) and opening(opened, closed). The data evaluated by a multiple ranking test were analyzed by mean, paired t-test, ANOVA and Duncans multiple raged test. The results are summarized as follows: 1) The classic style suits-middle aged womans body construct looks better when she is wearing it with the combination of suit details; opened tailored collar jacket with flap pocket or non-pocket, opened stand collar jacket with non-pocket, closed soutien collar and round neckline jacket with non-pocket, closed V-neckline jacket with flap pocket or non-pocket on slacks. 2) The middle aged woman wearing slacks looks smaller in upper body, longer in lower part of her body and taller as a whole than when wearing a skirt suit. And Opened jacket makes a middle aged woman be seen with less appeared abdomen than that on closed jacket. The stand calar and round neckline jacket with non-flap pockets makes her look smaller in upper body and hip. 3) With tailored, soutien, stand collar jacket, it looks slimmer in a neck, narrower in shoulder, smaller in upper body, and taller than on a round neckline and V-neckline jacket.

• Journal of Acupuncture Research
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• v.28 no.4
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• pp.9-18
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• 2011

Objectives : This study was performed to evaluate the effects of the acupuncture therapy in combination with Soyeom pharmacopuncture therapy on acute whiplash injury by traffic accident. And thermal change of posterior neck and shoulder was observed. Methods : The clinical study was conducted to 20 cases of acute whiplash injury patients who had been admitted in Dept. of Acupuncture and Moxibusion, Woosuk University Hospital from December 1, 2010 to May 31, 2011. The patients were randomly divided into two groups. In one group(test group), patients were treated with the acupuncture therapy in combination with Soyeom pharmacopuncture therapy. And in the other group(control group), patients were treated with acupuncture therapy only. To estimate the efficacy of treatments, visual analog scale(VAS), neck disability index(NDI) of posterior neck pain were checked. And also thermal change of posterior neck and shoulder was observed by digital infrared thermographic imaging(DITI). Results : Both group represented effective improvement in VAS and NDI of posterior neck pain. Especially, test group is more effective than control group in VAS comparison, statistically. In test group, temperature of posterior neck and shoulder was decreased after treatments. But there was no significant difference between two groups on thermographic change. Conclusions : Through this study, Soyeom pharmacopuncture therapy is considered to be effective for reducing pain in acute whiplash injury patients. And after Soyeom pharmacopuncture therapy, temperature of posterior neck and shoulder show a tendency to decrease.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.35 no.12
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• pp.1599-1606
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• 2011

It is possible to study the load characteristics of full-scale hingeless rotor with the changing of physical smallscaled configurations such as rectangular and paddle blades, and metal and composite hubs. In this study, a static test, and a ground and wind-tunnel test were carried out using small-scale rotor models. The static test was carried out to confirm structural stiffness, characteristics of inertia, natural frequency, and damping ratio of rotors, and the ground and wind-tunnel test was carried out to confirm the stability and aerodynamic characteristics under hovering and forward flight conditions. According to the test results, the vertical load in the case of a combination of a small composite hub with paddle blades was higher than that in the case of a metal hub with paddle blades at same condition. Further, it was confirmed that the restraint of the combination of composite hub can be more flexible than the metal hub for the motion of paddle blades.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.2063-2068
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• 2012

Aim: Liquid-based cytology is the most often used method for cervical cancer screening, but it is relatively insensitive and frequently gives equivocal results. Used as a complementary procedure, the high-risk human papillomavirus (HPV) DNA test is highly sensitive but not very specific. The human telomerase RNA gene (TERC) is the most often amplified oncogene that is observed in cervical precancerous lesions. We assessed genomic amplification of TERC in liquid-based cytological specimens to explore the optimal strategy of using this for cervical cancer screening. Methods: Six hundred and seventy-one residual cytological specimens were obtained from outpatients aged 25 to 64 years. The specimens were evaluated by the Digene Hybrid Capture 2 (HC2) HPV DNA test and fluorescence in situ hybridization (FISH) with a chromosome probe to TERC (3q26). Colposcopic examination and histological evaluation were performed where indicated. Results: The TERC positive rate was higher in the CIN2+ (CIN2, CIN3 and SCC) group than in the normal and CIN 1 groups (90.0% vs. 10.4%, p < 0.01). In comparison with the HC2 HPV DNA test, the TERC amplification test had lower sensitivity but higher specificity (90.0% vs. 100.0%, 89.6% vs. 44.0%, respectively). TERC amplification test used in conjunction with the HC2 HPV DNA test showed a combination of 90.0% sensitivity and 92.2% specificity. Conclusion: The TERC amplification test can be used to diagnose cervical precancerous lesions. TERC and HPV DNA co-testing shows an optimal combination of sensitivity and specificity for cervical cancer screening.

• Journal of Veterinary Clinics
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• v.20 no.1
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• pp.7-11
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• 2003

The selection of a test as a reference with no perfect sensitivity and specificity may lead to bias, yielding distortion of the diagnostic performance. This means it is inappropriate to use imperfect diagnostic tests as a reference method to identify infected patients in clinical environments. In this study, diagnostic performance of rapid urease test, polymerase chain reaction (PCR), and histology of gastric biopsy specimens for diagnosing Helicobacter pylori infection separately and in combination was estimated by using non-linear regression. Based on this approach, the sensitivity, specificity and likelihood ration positive and negative values for each test were as follows: urease test 99.9%, 99.9%, 99.9%, 99.6%, respectively; PCR 88.6%, 99.9%, 99.9%, 70.5%, respectively; histology 78.3%, 97%, 78.3%, 97%, respectively. Predictive values for positive and negative changes with varying Combination of three diagnostic tests employed in the study gives no substantial benefit for practitioners to screen infected patients, and urease test or PCR represents an appropriate single test in clinical environments.

• The Korean Journal of Applied Statistics
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• v.32 no.3
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• pp.331-348
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• 2019

Understanding the tumor heterogeneity due to differences in the growth pattern of metastatic tumors and rate of change is important for understanding the sensitivity of tumor cells to drugs and finding appropriate therapies. It is often possible to test for differences in population means using t-test or ANOVA when the group of N samples is distinct. However, these statistical methods can not be used unless the groups are distinguished as the data covered in this paper. Statistical methods have been studied to test heterogeneity between samples. The minimum combination t-test method is one of them. In this paper, we propose a maximum combinatorial t-test method that takes into account combinations that bisect data at different ratios. Also we propose a method based on the idea that examining the heterogeneity of a sample is equivalent to testing whether the number of optimal clusters is one in the cluster analysis. We verified that the proposed methods, maximum combination t-test method and gap statistic, have better type-I error and power than the previously proposed method based on simulation study and obtained the results through real data analysis.