• Archives of Pharmacal Research
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• 제15권1호
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• pp.41-47
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• 1992

In order to obtain acetaminophen, a popular analgesic-antipyretic, though microbial p-hydroxylation and N-acetylation of aniline, various Streptomyces strains were screened. Aniline N-acetylation activity was rather ubiquitous but-hydroxylation activity was selective. Microbial conversion pathway of aniline to acetaminophen was considered to be through N-acetylation and p-hydroxylation or vice versa. However, depending on species used, o-hydroxylation and its degradation activity (S. fradiae) and acetaminophen degradation activity (S. coelicolar) were also detected. Among the screened Streptomyces strains, S fradiae NRRL 2702 showed the highest acetanilide p-hydroxylation activity (203% conversion rate). Furthermore, in S. fradiae carbon source and its concentration, phosphate ion concentration and pH of growth medium were found to play the crucial roles in p-hydroxylation activity. Through the proper combination of factors mentioned above, the ten times more activity (26-30% conversion rate) was attained.

• 대한전자공학회논문지SP
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• 제42권1호
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• pp.33-42
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• 2005

칼라 화소 성분들은 인쇄에서부터 획득하기까지의 전 과정에 거쳐 심하게 왜곡되기 때문에, 획득된 영상에서 정확한 칼라 정보를 필요로 하는 칼라 코트 식별 작업은 매우 어렵다. 정확한 칼라 식별을 달성하기 위해서는 서로 다른 칼라 영역들을 정화하게 분리해냄으로써 어떤 칼라 영역의 부분이 아닌 전체 화소들에 대한 통계적 처리를 가능하게 하는 영역 분할 기술이 필요하다. 칼라 영역 분한은 성분 영상(들)에 대한 경계선 검출을 수행하여 달성할 수 있다. 이 논문에서는 RGB, HSI, YIQ의 세 칼라 모델로부터의 성분 영상들에 대해 독립적으로 경계선을 검출하고, 결합에 의해 가장 완전한 경계선 영상을 제공하는 한쌍의 성분을 찾아내기 위한 수학적 분석과 실험을 수행하였다. 실험 결과, Y-와 R-성분 경계선 영상들을 결합했을 때 가장 좋은 결과를 얻을 수 있었다.

• 대기
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• 제31권1호
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• pp.29-43
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• 2021

In this study, two-step statistical approach including Principal Component Analysis (PCA) and Multiple Linear Regression (MLR) was employed, and main meteorological factors explaining the high-PM2.5 episodes were identified in two regions: Seoul and Busan. We first performed PCA to isolate the Principal Component (PC) that is linear combination of the meteorological variables observed at two levels: surface and 850 hPa level. The employed variables at surface are: temperature (T2m), wind speed, sea level pressure, south-north and west-east wind component and those at 850 hPa upper level variables are: south-north (v850) and west-east (u850) wind component and vertical stability. Secondly we carried out MLR analysis and verified the relationships between PM2.5 daily mean concentration and meteorological PCs. Our two-step statistical approach revealed that in Seoul, dominant factors for influencing the high PM2.5 days are mainly composed of upper wind characteristics in winter including positive u850 and negative v850, indicating that continental (or Siberian) anticyclone had a strong influence. In Busan, however, the dominant factors in explanaining in high PM2.5 concentrations were associated with high T2m and negative u850 in summer. This is suggesting that marine anticyclone had a considerable effect on Busan's high PM2.5 with high temperature which is relevant to the vigorous photochemical secondary generation. Our results of both differences and similarities between two regions derived from only statistical approaches imply the high-PM2.5 episodes in Korea show their own unique characteristics and seasonality which are mostly explainable by two layer (surface and upper) mesoscale meteorological variables.

• ALGAE
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• 제31권2호
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• pp.85-90
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• 2016

It is shown by the heterogenous nature of Borzi’s description and illustrations that Hormotila mucigena Borzi, the generitype of Hormotila, should be redefined. Borzi’s original description and accompanying illustrations of Hormotila (constituting the protologue) correspond to a minimum of five distinct genera of green algae. Two distinct concepts of the genus have persisted over the years. The genus has become based on a combination of palmelloid and physiologically stressed forms of two of the component algae. Our understanding of the genus is further confused by the incorporation of unrelated unicellular and colonial coccoid forms. There are only one or two distinctive attributes that would allow the selection of any one of the five forms as representing the genus and species. One of Borzi’s original figures is proposed to redefine the original species of the genus, Hormotila mucigena.

• 전력전자학회:학술대회논문집
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• 전력전자학회 2005년도 전력전자학술대회 논문집
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• pp.659-662
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• 2005

In this paper, we proposed the novel hybrid multi-level inverter using combination of the output voltage of transformers to reduce the THD(Total Harmonic Distortion) and improve the waveform of output voltage. The proposed multi-level inverter used the output of transformer which is 1times, 2times, 4times of input of the transformers. So we increased the output voltage from the reduce the number of switching component and transformer. Also, we tested the proposed prototype 15-level inverter to clarify the proposed electric circuit and reasonableness of control signal for the proposed multi -level PWM inverter.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1998년도 추계학술대회 논문집 학회본부A
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• pp.37-39
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• 1998

The hybrid step motor has found applications in a wide range of mechanical systems as a low cost, open-loop positioning device. The step motor provides good stiffness at rest against disturbing load influences, a combination of moderate speed fine resolution, high reliability and simplicity. In recent years, considerable competition has arisen over the technological issue of wheather the device should be applied as a 2-Phase or 5-Phase machine. In this paper, to compare two systems, we have atempted to derive the mathematical. model, and analysed operating detent torque with this model. The analysis shows that a fundamental component of the permeance distribution produces the average torque and that harmonic components produce the ripple torque.

• 한국수자원학회논문집
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• 제56권spc1호
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• pp.1007-1014
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• 2023

천수방정식 기반 흐름해석모형은 하천 및 수로에서의 흐름을 수평 2차원적으로 수치모의하는데 활용되며 매개변수인 와점성계수와 조도계수에 큰 영향을 받는다. 따라서 적절한 매개변수의 선택은 흐름특성을 정확하게 모사하기 위해 매우 중요하다. 본 연구에서는 2차원 흐름해석에 적용되는 매개변수의 최적조합을 찾기 위한 자동화 알고리즘을 개발하고 적용하였다. 기존연구에서 2차원 흐름해석모형을 적용하는 경우 매개변수의 선정에 있어 경험적인 방법을 사용하여 최적의 매개변수를 찾는데 어려움이 있었다. 따라서 본 연구에서는 실험결과를 활용하여 다양한 매개변수의 조합에 따른 오차를 추적하고, 매개변수의 최적조합을 결정할 수 있는 알고리즘을 Python 언어를 이용하여 개발하고 적용하였다. 자동화 알고리즘은 121(11×11)개의 매개변수 조합에 따른 2차원 흐름해석결과 중 유속모의결과의 오차값을 비교하여 가장 정확한 조합을 손쉽게 결정하도록 구성되었다. 오차가 가장 작은 매개변수의 최적조합을 자동화 알고리즘의 적용을 통해 신속하고 간단하게 결정할 수 있다는 측면에서 높은 활용가치가 있을 것으로 기대된다.

• 소성∙가공
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• 제27권6호
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• pp.356-362
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• 2018

A liner is a crucial component that directly affects the penetration performance of the shaped charge warhead. If the material of the liner has fine grain size and high strength, then the penetration performance can be further improved. There have been attempts to use a preform obtained by a severe plastic deformation (SPD) process. In this study, the process of minimizing the strain deviation to maintain the characteristics of material obtained by the severe plastic deformation process was investigated. The FE analysis of liner forging process was performed using the design of experiments (DOE), to optimize various shape parameters of the forming process such as shape of preform and forging die. As a result, the combination of design variables with the minimum effective strain deviation in the liner forging process were obtained.

• 한국실내디자인학회:학술대회논문집
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• 한국실내디자인학회 1999년도 춘계학술발표대회 논문집
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• pp.57-60
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• 1999

The eyes are the first sensory organs to perceive the environment. We become accustomed to the environment with our eyes. When we contact the environment, we perceive the appearance of an object with our eyes. Then we recognize our position, and perceive the shape surrounding the object interacting with space. The perception of seeing constructs experiences which control most of our recognition, and the experiences are images of the environment surrounding it. So they are significantly expressed into sensitive and mental elements of material and non-material world. Gibson's ecological perception theory analyzes and information system, which helps man to move effectively, and its component stimulus'. The important thing is that we should understand the combination of systems gathering stimulus not as an individual system but as one whole system.

• Natural Product Sciences
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• 제14권1호
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• pp.27-31
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• 2008

We have evaluated the combined antifungal effects of the essential oil from Eucalyptus globulus or its main component 1,8-cineole with ketoconazole. Checkerboard microtiter tests were used to analyze their effects against three Candida and six Trichophyton species. The susceptibility of the Trichophyton species to E. globulus essential oil differed distinctly. The fractional inhibitory concentration indices (FICIs) against the tested Candida species ranged between 0.09 and 0.38 for ketoconazole combined with E. globulus essential oil or 1,8-cineole, indicating significant synergism between ketoconazole and the oil samples. Similar experiments using Trichophyton species resulted in FICIs between 0.28 and 0.63, indicating relatively weaker combined effects than those observed with Candida species. Thus, the data reported here show that the anti-Candida effects of ketoconazole can be significantly improved in the presence of E. globulus essential oil or 1, 8-cineole.