• Current Applied Physics
• /
• 제18권11호
• /
• pp.1275-1279
• /
• 2018

We investigate the change of the Fano effect by considering one Majorana zero mode to couple laterally to the single-dot Fano interferometer. It is found that the Majorana zero mode quenches the Fano effect thoroughly and causes the conductance to be independent of the dot level, the dot-lead coupling, and the increase of the Majorana-dot coupling. As a result, the linear conductance becomes only related to the interlead coupling and the magnetic-flux phase factor. These results can be helpful for the detection of Majorana zero mode.

• 대한약학회:학술대회논문집
• /
• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
• /
• pp.231.3-232
• /
• 2003

The biomedical applications of chitosan have been widely researched. FN mediates its biological effects through binding to the hetero-dimeric transmembrane glycoproteins, integrins, which physically couple the cytoskeleton to the ECM. FN binds to the integrin through a consensus site including the Arg-Gly-Asp (RGD) sequence within tenth type III module (Ruoslahti & Pierschbacher 1987). A short sequence Pro-His-Ser-Arg-Asn (PHSRN) has also been identified as a synergistic motif within ninth type III module for binding to ${\alpha}$5${\beta}$1 integrin (Aota et al. 1994). (omitted)

• Journal of Nutrition and Health
• /
• 제40권8호
• /
• pp.753-761
• /
• 2007

The objective of our study was to evaluate the dietary intakes and eating habit for seniors utilizing ten different social welfare centers in Seoul, Korea. The total number of subjects of this study was 543(male: 199, female: 344) of 60 years of age or older. The survey was performed through personal interview questionnaires from May 3rd to June 1st 2006. After assigning subjects to four categories based on family type, single, couple, joint family, and other, these categories were compared with the estimated total nutrient intakes and eating habit. Validity was assessed by comparison with 24-hour dietary recalls and dietary variety score(DVS). The results showed that senior in single family type was far lower than that of couple family type in terms of frequency of meal per day and intake of snacks. Dietary variety score represented that a single female with social security beneficiary showed the lowest variety score compared with other family type. The lunch meal provided by social welfare center turned out to be the most nutritious diet and had significant proportion of daily intakes in essential nutrients such as protein, iron, vitamin A, and vitamin C. Taken together, the family type was a significant factor and the accompaniment is another effector on dietary pattern in the elderly. We strongly suggest that the current lunch program in welfare center should be expanded to breakfast meal, and furthermore the small commodity program is also needed to provide the elderly with meal for social communication.

• 대한간호학회지
• /
• 제38권5호
• /
• pp.639-648
• /
• 2008

Purpose: This study was designed to construct and test a structural equation model on sexual function in women with gynecologic cancer. Methods: The model was constructed and tested under the hypotheses that women's physical changes in sexual function after gynecologic cancer treatment did not automatically lead to sexual dysfunctions. Women's psychosocial factors were considered to be mediating variables. Two hundred twelve women with cervical, ovarian, and endometrial cancer were recruited and asked to complete a survey on their physical factors, psychosocial factors and sexual function. Data was analyzed using SPSS WIN 12.0 and Amos WIN 5.0. Results: Predictors of sexual function in the final model were sexual attitude affected by physical distress and couple's age, sexual information affected by physical distress and couple's age, depression affected by physical distress, and marital intimacy affected by physical distress. Tumor stage and time since last treatment directly affected women's sexual function without any mediating psychosocial variables. However, body image did not affect women's sexual function. Conclusion: Nursing professionals should develop a tailored educational program integrating both physical and psychosocial aspects, and apply it to women and their spouses in order to promote sexual function in women with gynecologic cancer.

• Geomechanics and Engineering
• /
• 제28권5호
• /
• pp.477-491
• /
• 2022

In the present study, the effects of thermal loading on the buckling and resonance frequency of graphene platelets (GPL) reinforced nano-composites are examined. Functionally graded (FG) material properties are considered in thickness direction for the thermal responses of the composite. The equivalent material properties are obtained using Halphin-Tsai nano-mechanical model for composite layers. Moreover, the effects of nano-scale sizes are taken into account, employing functionally modified couple stress (FMCS) parameter. In this regard, for the first time, it is demonstrated that at certain values of GPL weight fraction, thermal buckling occurs. In obtaining results of vibrational behavior, both analytical solution and deep neural network (DNN) methods are used. The DNN method needs low computational costs to predict the resonance behavior. A comprehensive parametric study is conducted to indicate the effects of several geometrical, material, and loading conditions on the vibrational and buckling behavior of cylindrical shell structures made of GPL-nanocomposites. It is shown that the effect of temperature change on the occurrence of buckling is vital while it has a negligible impact on the resonance frequency of the structure. Moreover, the size-dependency of the results is demonstrated, and it cannot be neglected in nano-scales.

• Clinics in Shoulder and Elbow
• /
• 제17권1호
• /
• pp.44-47
• /
• 2014

Typically, massive rotator cuff tears have stiff and retracted tendon with poor muscle quality, in such cases orthopaedic surgeons are confronted with big challenging to restore the cuff to its native footprint. Furthermore, even with some restoration of the footprint, it is related with a high re-tear rate due to less tension free repair and less tendon coverage. In this tough circumstance, the partial repair has yielded satisfactory outcomes at relatively short follow-up by re-creating the transverse force couple of the rotator cuff. Through this partial repair, the massive rotator cuff tear can be converted to the "functional rotator cuff tear" and provide improvement in pain and functional outcomes in patient's shoulder.

• 제어로봇시스템학회논문지
• /
• 제1권1호
• /
• pp.58-62
• /
• 1995

Necessarily, it is required to analyze interfacial mechanism between tire and road for understanding tire wear, vehicle tracking and breaking. Therefore, there have been some efforts to measure 3-axis pressure and 2-axis displacement on tire road interface. But it was so hard to couple precisely measuring sensor and desired point on tire tread pattern block that it was impossible to analyze the mechanism on commercial tire with tread pattern. To overcome such a problem, a on-line measurement system is proposed in this paper. And an automatic control system is designed to test the tire with similar configuration of real vehicle driving.

• International Journal of Computer Science & Network Security
• /
• 제22권6호
• /
• pp.91-96
• /
• 2022

The photocatalytic degradation of salicylic acid takes place in several stages involving coupled phenomena, such as the transport of molecules and the chemical reaction. The systems of transport equations and the photocatalytic reaction are numerically solved using COMSOL Mutiphysics (CM) simulation software. CM will make it possible to couple the phenomena of flow, the transport of pollutants (salicylic acid) by convection and diffusion, and the chemical reaction to the catalytic area (bauxite or TiO2 doped by nanoparticles). The simulation of the conversion rate allows to correctly fit the experimental results. The temporal simulation shows that the reaction reaches equilibrium after a transitional stage lasting over one minute. The outcomes of the study highlight the importance of diffusion in the boundary layer and the usefulness of injecting micro-agitation into the microchannel flow. Under such conditions, salicylic acid degrades completely.

• 대한간호학회지
• /
• 제47권3호
• /
• pp.367-379
• /
• 2017

Purpose: This study aimed to understand and describe the caring experiences of spouses of elderly people with dementia. Methods: The hermeneutic phenomenological method was used and participants were 12 spouses aged 65 and over who were taking care of their husbands or wives with dementia at home. Data were collected from individual in-depth interviews on participants' actual caring experiences. Additionally, novels, movies, and memoirs on elderly couples with partner who had dementia were included as data for the analysis. The qualitative data analysis software program was used to manage and process the collected qualitative data. Data were analyzed using hermeneutic phenomenological analysis based on four fundamental existentials including lived body, lived space, lived time, and lived others. Results: Five essential themes emerged from the analysis: 1) body moving like an old machine, 2) swamp of despair filling with hope, 3) sweet time after bitterness, 4) disappointed elderly couple in the empty nest, and 5) unappreciation vs. empathetic feelings. These essential themes were comprehensively summarized as "the road leading to the maturation of life with dedication and hope while bearing the weight of caring based on the couple's relationship." Conclusion: The findings indicate that the nature of the caring experience of spouses of elderly individuals with dementia is filled with many dynamic and paradoxical dimensions. Thus, results of the study would help with developing interventions tailored specifically for elderly spouse caregivers to support their role adaptation and ultimately improving their quality of life.

• BMB Reports
• /
• 제56권2호
• /
• pp.126-131
• /
• 2023

The abnormal accumulation and aggregation of the misfolded α-synuclein protein is the neuropathological hallmark of all α-synucleinopathies, including Parkinson's disease. The secreted proteins known as netrins (netrin-1, netrin-3, and netrin-4) are related to laminin and have a role in the molecular pathway for axon guidance and cell survival. Interestingly, only netrin-1 is significantly expressed in the substantia nigra (SN) of healthy adult brains and its expression inversely correlates with that of α-synuclein, which prompted us to look into the role of α-synuclein and netrin-1 molecular interaction in the future of dopaminergic neurons. Here, we showed that netrin-1 and α-synuclein directly interacted in pre-formed fibrils (PFFs) generation test, real time binding assay, and co-immunoprecipitation with neurotoxin treated cell lysates. Netrin-1 deficiency appeared to activate the dopaminergic neuronal cell death signal pathway via α-synuclein aggregation and hyperphosphorylation of α-synuclein S129. Taken together, netrin-1 can be a promising therapeutic molecule in Parkinson's disease.