• Korean Journal of Clinical Laboratory Science
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• v.45 no.1
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• pp.5-8
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• 2013

In the specimen of free PSA in the low concentration, the result in % bias from our institution and comparable evaluation institution was -33.7% which is exceeded % bias ${\pm}20%$ ; however, it was the domestically allowable limit recommended by the laboratory accreditation commission for specimen at the low concentration. In this paper, the cause was accredited by instability of free PSA substance within the specimen, and the specimen stability test was performed according to CLSI documents GP29-A2. After the low and high concentration specimen were made, and rapidly cooled down in a deep freezer with $-30^{\circ}C$, serum of two concentrations was measured for 10 consecutive days with 3 times a day by Architect i2000 and observed a change in the mean value. As the results of two groups, there were changes in the established target value, and a change level was evaluated by calculating it with % bias. The low concentration specimen had no significant reduction until the 4 day lapse in cold storage. However, % bias were reduced by -17.5% from the 5 day lapse, by 21.5% after the 7 day lapse, and by -26.9% after the 9 day lapse. The frozen specimen had only intra-day variation for 10 days. In the high concentration specimen, bias began to show as -12.2% from the 3 day lapse in cold storage. There was reduction by -28.9% from the 5 day lapse, by -39% after the 7 day lapse, and by -42.9% after the 9 day lapse. In the frozen specimen, there was only intra-day variation like the low concentration specimen in cold storage.

• Atmosphere
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• v.32 no.4
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• pp.277-295
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• 2022

The global weather prediction model, Korean Integrated Model (KIM), has been in operation since April 2020 by the Korea Meteorological Administration. This study assessed the performance of heat waves (HWs) in Korea in 2020. Case experiments during 2018-2020 were conducted to support the reliability of assessment, and the factors which affect predictability of the HWs were analyzed. Simulated expansion and retreat of the Tibetan High and North Pacific High during the 2020 HW had a good agreement with the analysis. However, the model showed significant cold biases in the maximum surface temperature. It was found that the temperature bias was highly related to underestimation of downward shortwave radiation at surface, which was linked to cloudiness. KIM tended to overestimate nighttime clouds that delayed the dissipation of cloud in the morning, which affected the shortage of downward solar radiation. The vertical profiles of temperature and moisture showed that cold bias and trapped moisture in the lower atmosphere produce favorable conditions for cloud formation over the Yellow Sea, which affected overestimation of cloud in downwind land. Sensitivity test was performed to reduce model bias, which was done by modulating moisture mixing parameter in the boundary layer scheme. Results indicated that the daytime temperature errors were reduced by increase in surface solar irradiance with enhanced cloud dissipation. This study suggested that not only the synoptic features but also the accuracy of low-level temperature and moisture condition played an important role in predicting the maximum temperature during the HWs in medium-range forecasts.

• Restorative Dentistry and Endodontics
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• v.47 no.4
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• pp.40.1-40.18
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• 2022

Objectives: This study aimed to investigate the influence of different obturation techniques compared to cold lateral compaction on the success rate of primary non-surgical endodontic treatments. Materials and Methods: Systematic searches were performed for studies published up to May 17^th, 2022 in MEDLINE/PubMed, Cochrane Library, Web of Science, Scopus, EMBASE, and Grey Literature Reports. Randomized clinical trials and nonrandomized (nonrandomized clinical trials, prospective or retrospective) studies that evaluated the success rate of primary non-surgical endodontic treatments obturated with the cold lateral compaction (control) and other obturation techniques were included. The revised Cochrane risk of bias tools for randomized trials (RoB 2) and nonrandomized studies of interventions (ROBINS-I) were used to evaluate the risk of bias. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) tool was used to evaluate the certainty of evidence. Results: Eleven studies (4 randomized clinical trials (RCTs), 4 prospective, and 3 retrospectives) were included. Two RCTs were classified as having some concerns risk of bias and 2 as a low risk of bias. Two nonrandomized studies were classified as having a critical risk of bias and 5 as having a moderate risk of bias. The GRADE analysis demonstrated a very low to moderate certainty of evidence. Conclusions: This systematic review generally evidenced no differences in the success rate of primary non-surgical endodontic treatments when the cold lateral compaction technique and other obturation techniques are performed. Further well-designed studies are still necessary.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.41 no.2
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• pp.59-64
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• 2004

In this paper, a Cold PHEMT equivalent circuit was proposed, and it is applied to extract extrinsic resistances. By using the proposed Cold PHEMT equivalent circuit, the variation of impedance with frequency and bias were mainly emphasized. Especially, the convergence of impedance with frequency and the change in impedance with bias were carefully analyzed, which may be used for fast extraction of extrinsic resistances. The proposed extraction method demonstrated improving of small signal model accuracy than conventional extraction method.

• Atmosphere
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• v.18 no.4
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• pp.507-524
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• 2008

In this paper, future climate changes over East Asia($20^{\circ}{\sim}50^{\circ}N$, $100^{\circ}{\sim}150^{\circ}E$) are projected by anthropogenic forcing of greenhouse gases and aerosols using coupled atmosphere-ocean general circulation model (AOGCM) simulations based on Intergovernmental Panel on Climate Change (IPCC) Special Report on Emissions Scenarios (SRES) B1, A1B and A2 scenarios. Before projection future climate, model performance is assessed by the $20^{th}$ Century (20C3M) experiment with bias, root Mean Square Error (RMSE), ratio of standard deviation, Taylor diagram analysis. The result of examination of the seasonal uncertainty of T2m and PCP shows that cold bias, lowered than that of observation, of T2m and wet bias, larger than that of observation, of PCP are found over East Asia. The largest wet bias is found in winter and the largest cold bias is found in summer. The RMSE of temperature in the annual mean increases and this trend happens in winter, too. That is, higher resolution model shows generally better performances in simulation T2m and PCP. Based on IPCC SRES scenarios, East Asia will experience warmer and wetter climate in the coming $21^{st}$ century. It is predict the T2m increase in East Asia is larger than global mean temperature. As the latitude goes high, the warming over the continents of East Asia showed much more increase than that over the ocean. An enhanced land-sea contrast is proposed as a possible mechanism of the intensified Asian summer monsoon. But, the inter-model variability in PCP changes is large.

• Atmosphere
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• v.28 no.4
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• pp.357-367
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• 2018

In this study, the temperature bias of aircraft observation was estimated through comparison with sonde observation prior to developing the temperature bias correction method at the Korea Institute of Atmospheric Prediction Systems (KIAPS). First, we tried to compare aircraft temperature with collocated sonde observations at 0000 UTC on June 22, 2012. However, it was difficult to estimate the temperature bias due to the lack of samples and the uncertainty of the sonde position at high altitudes. Second, we attempted a background innovation comparison for sonde and aircraft using KIAPS Package for Observation Processing (KPOP). The one month averaged background innovation shows the aircraft temperature have a warm bias against sonde for all levels. In particular, there is a globally distinct warm bias about 0.4 K between 200 hPa and 300 hPa corresponding to flight level. Spatially, most of the areas showed the warm bias except for below 300 hPa in some part of China at 0000 and 1200 UTC and below 850 hPa in Australia at 0000 UTC. In general, the temperature bias was larger at 1200 UTC than 0000 UTC. Based on the estimated temperature bias, we have applied the static bias correction method to the aircraft temperature observation. As a result, the warm bias of the aircraft temperature has decreased at most levels, but a slight cold bias has occurred in some areas.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.7 no.4
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• pp.743-749
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• 2003

By biasing the gate of cold-HEMT with a voltage slightly lower than the pinch-off point, a new small-signal modeling method that is free from gate degradation problem and requires no additional DC measurement is proposed in this paper. The method has shown excellent agreement between modeled and measured S-parameters up to 62 GHz at 49 different normal operating bias points.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.36 no.4
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• pp.122-144
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• 2023

Objectives : The purpose of this study is to evaluate the effects of herbal medicine treatment in patients with cold urticaria. Methods : We searched randomized controlled trials(RCTs) reporting the effects of herbal medicine for cold urticaria through domestic and international databases from their inception to September 2023. The results were summarized in tables. We assessed the risk of bias in included RCTs through Cochrane risk of bias tool and the data synthesis was conducted through RevMan version 5.4. Results : A total of 12 RCTs were included in this review and all trials compared herbal medicine alone treatment(treatment group) with western medicine alone treatment(control group). The total effective rate(TER) of treatment group was statistically higher than that of control group(RR: 1.49, 95% CI: 1.38 to 1.62, p<0.00001, I²=65%). On the other hand, when comparing except for 1 trial with different evaluation period, the TER of treatment group was statistically higher than that of control group and heterogeneity was very low(RR: 1.36, 95% CI: 1.26 to 1.47, p<0.00001, I²=0%). And when comparing 8 trials using the total symptom score(TSS) change index as an indicator of TER, the TER of treatment group was statistically higher than that of control group and heterogeneity was very low(RR: 1.38, 95% CI: 1.26 to 1.51, p<0.00001, I²=0%). The treatment group showed more statistically significant decrease compared to the control group in TSS(MD: -2.51, 95% CI: -2.63 to -2.40, p<0.00001, I²=99%). The relapse rate of treatment group was statistically lower than that of control group(RR: 0.19, 95% CI: 0.10 to 0.40, p<0.00001, I²=0%). Mild adverse events such as sleepiness, dizziness were reported in control group and gastric discomfort was reported in treatment group. In the risk of bias assessment, many cases were evaluated as 'Unclear risk'. Conclusions : This review found that herbal medicine alone treatment could more effective and safe than western medicine alone treatment for cold urticaria. But further well-designed researches are needed because of heterogeneity between trials and the quality of the included trials.

• Journal of Advanced Marine Engineering and Technology
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• v.18 no.2
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• pp.54-63
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• 1994

Mg thin films were prepared on SPCC(cold-rolled steel) substrates by vasuum evapoaration and ion-plating. The influence of argon gas pressure and substrates bias voltage on the crystal orientation and morphology of the film was determined by using X-ray diffraction and scanning electron micrography (SEM), respectively. And the effect of crystal orientation and morphology of the Mg thin films on corrosion behavior was estimated by measuring the anodic polarization curves in deaerated 3% NaCl solution. The crystal orientation of the Mg films deposited at high argon gas pressure exhibited a (002) preferred orientation, regardless of the substrate bias voltage. Film morphology changed from a columnar to a granular structure with the increase of argon gas pressure. The morphology of the films depended not only on argon gas pressure but also bias voltage ; i.e., the effect of increasing bias voltage was similar to that of decreasing argon gas pressure. The influences of argon gas pressure and bias voltage were explained by applying the adsorption inhibitor theory and the sputter theory. And also, this showed that the corrosion resistance of the Mg thin films can be changed by controlling the crystal orientaton and morphology.

• Journal of the Korean Ceramic Society
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• v.34 no.3
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• pp.296-302
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• 1997

The effect of cold cyclic compaction on densification of SiC whisker/Al2O3 composite was investigated. Re-lative density of the compact increased as the number of cycle and the compaction pressure increased and the bias pressure decreased. The rate of loading and unloading and the frequency of cold cyclic compaction did not affect much on sliding and rearrangement of the particles. Fracture of SiC whisker was hardly ob-served during cold cyclic compaction and the direction of whisker was randomly oriented throughout the compact regardless of the direction of compaction. Thus, cold cyclic compaction may be an efficient method to densify SiC whisker/Al2O3 composite.