• 대한본초학회지
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• 제30권2호
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• pp.43-48
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• 2015

Objectives : The aim of this study was to investigate the memory enhancing properties of extract of Hoelen Cum Radix (HCR) and its possible mechanism in mice of normal condition. Methods : We evaluated the effects of HCR on cognitive function and memory enhancement in normal mice. Male ICR mice were orally administrated with HCR 100 mg/kg for 7 days and equal volume of saline was administrated to the control group in the same condition. We conducted two behavioral tests which measure the spatial working memory (Y-maze test) and cognitive fear memory (passive avoidance test). We also investigated whether HCR affects the hippocampal neurogenesis in the brain. To assess the effects of HCR on neural progenitor cell differentiation and neurite outgrowth in the early stage of hippocampal neurogenesis, we performed doublecortin (DCX), a direct neurogenesis marker, immunohistochemical analysis in the dentate gyrus (DG) of the mouse hippocampus. Results : HCR significantly enhanced memory and cognitive function as determined by the Y-maze test (p<0.05) and passive avoidance test (p<0.001). Moreover, HCR increased DCX positive cells (p<0.01) and neurite length (p<0.01) compared to the control group. These results indicated that HCR stimulates differentiation of neural progenitor cells and promotes neurite outgrowth in hippocampal DG of the mice. Conclusion : We concluded that HCR shows memory enhancing effects through the stimulation of hippocampal neurogenesis as a consequence of accelerated neuronal differentiation and neurite outgrowth in the DG of the hippocampus after HCR treatment.

• 한국심리학회지 : 문화 및 사회문제
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• 제11권spc호
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• pp.117-131
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• 2005

본 논문은 현재 우리사회에서 문제가 대두되고 있는 준법의식의 약화에 대한 설명과 관련될 수 있는 다양한 관점의 심리학적 이론들 비교분석하고, 특히 준법의식 약화에서 인지부조화 기제의 역할에 대한 이론적 실증적 연구들을 개관요약하였다. 이를 위해 범죄의 현상과 원인을 설명하는 고전이론, 유전학과 생물학적 이론과 정신분석학, 성격이론, 지능/도덕성 발달, 의사결정이론 과 같은 심리학적 이론들의 특성과 준법과 위법행동의 다양한 측면을 통합적으로 비교하였다. 이런 이론들이 현재의 범죄행동에 대한 설명을 제공하는데 초점을 맞춘다면, 사회학습이론과 인지부조화 이론은 직간접의 경험을 통한 준법의식의 변화에 대한 설명을 제공해 주고 있다. 특히 과거의 위법행동이 준법의식과 인지부조화와 부정적 각성을 일으키고, 이 각성을 없애기 위한 준법의식의 변화시킨다는 인지부조화적 관점은 사소한 법규위반이 낮아지는 준법의식의 부분적 원인이라는 것이 일련의 연구들을 통해 검증 되었다. 이런 인지부조화의 이론적 틀이 법률입안과 정책제안에 제안하는 시사점들을 논의하였다.

• Journal of Ginseng Research
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• 제48권1호
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• pp.59-67
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• 2024

Background: Alzheimer's disease (AD) has memory impairment associated with aggregation of amyloid plaques and neurofibrillary tangles in the brain. Although anti-amyloid β (Aβ) protein antibody and chemical drugs can be prescribed in the clinic, they show adverse effects or low effectiveness. Therefore, the development of a new drug is necessarily needed. We focused on the cognitive function of Panax ginseng and tried to find active ingredient(s). We isolated panaxcerol D, a kind of glycosyl glyceride, from the non-saponin fraction of P. ginseng extract. Methods: We explored effects of acute or sub-chronic administration of panaxcerol D on cognitive function in scopolamine- or Aβ_25-35 peptide-treated mice measured by several behavioral tests. After behavioral tests, we tried to unveil the underlying mechanism of panaxcerol D on its cognitive function by Western blotting. Results: We found that pananxcerol D reversed short-term, long-term and object recognition memory impairments. The decreased extracellular signal-regulated kinases (ERK) or Ca²⁺/calmodulin-dependent protein kinase II (CaMKII) in scopolamine-treated mice was normalized by acute administration of panaxcerol D. Glial fibrillary acidic protein (GFAP), caspase 3, NF-kB p65, synaptophysin and brainderived neurotrophic factor (BDNF) expression levels in Aβ_25-35 peptide-treated mice were modulated by sub-chronic administration of panaxcerol D. Conclusion: Pananxcerol D could improve memory impairments caused by cholinergic blockade or Aβ accumulation through increased phosphorylation level of ERK or its anti-inflammatory effect. Thus, panaxcerol D as one of non-saponin compounds could be used as an active ingredient of P. ginseng for improving cognitive function.

• 한국경영과학회지
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• 제23권4호
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• pp.203-212
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• 1998

본 논문에서는 FCM을 이용하여 의사결정의 질을 높일 수 있는 추론방법을 제시한다. 이를 위하여 FCM의 추론의 질을 저하시키는 문제중의 하나인 동기화 문제(synchronizatinon Problem)를 설명하고. 이를 해결하기 위한 방안으로서 FCM 계층화(levelization) 알고리즘을 제시한다. 본 논문에서 제안된 계층화된 FCM을 이용한 추론절차를 제시하고, 그 활용예를 설명한다.

• 한국시뮬레이션학회논문지
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• 제7권1호
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• pp.53-68
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• 1998

FCM은 비구조적인 (unstructured) 문제영역에서 주어진 문제에 대한 효과적인 추론시 적용될 수 있는 매우 유용한 추론도구이다. 그러나, FCM에 사이클이 존재하면 추론효과가 크게 감소한다. 본 노문에서는 사이클이 있는 FCM을 이용한 의사결정의 질을 높일 수 있는 추론방법을 제시한다. 아울러 사이클이 제거된 FCM의 추론이 질을 저하시키는 문제중의 하나인 동기화 문제 (synchronization problem)를 설명하고, 이를 해결하기 위한 방안으로서 FCM 계층화 (levelization) 알고리즘을 제시한다.

• 동아시아경상학회지
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• 제8권2호
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• pp.57-68
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• 2020

Purpose - This study investigated the effect of the social exclusion experience on the compulsive buying tendency. The purpose of current study is to examine the mechanism through compulsive buying, one of selfdefeating behaviors. While previous studies on compulsive buying focused only on the mechanism of psychological escapism to overcome negative emotions, this study intends to expand the study on the causes of compulsive buying by presenting a social exclusion experience as one of the causes of negative emotions. Research design and methodology - Present study was performed with 114 university students. Participants were assigned to one of two groups at random - the social exclusion experience group and the social exclusion nonexperience group. Authors analyzed the influence of social exclusion experience on the compulsive buying. Results - The social exclusion experience group showed compulsive buying tendency than the social exclusion non-experience group. Conclusions - People with social exclusion experiences avoid self-awareness and show cognitive narrowing, which leads to compulsive buying. Academic implications and practical implications of current research were discussed and the limitations were suggested.

• ETRI Journal
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• 제40권4호
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• pp.483-498
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• 2018

Nowadays, with progresses in robotic science, the design and implementation of a mechanism for human-robot interaction with a low workload is inevitable. One notable challenge in this field is the interaction between a single human and a group of robots. Therefore, we propose a new comprehensive framework for single-human multiple-robot remote interaction that can form an efficient intelligent adaptive interaction (IAI). Our interaction system can thoroughly adapt itself to changes in interaction context and user states. Some advantages of our devised IAI framework are lower workload, higher level of situation awareness, and efficient interaction. In this paper, we introduce a new IAI architecture as our comprehensive mechanism. In order to practically examine the architecture, we implemented our proposed IAI to control a group of unmanned aerial vehicles (UAVs) under different scenarios. The results show that our devised IAI framework can effectively reduce human workload and the level of situation awareness, and concurrently foster the mission completion percentage of the UAVs.

• The Journal of Korean Physical Therapy
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• 제16권2호
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• pp.90-98
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• 2004

Traumatic brain injury is an insult to the brain caused by an external physical force, that may product a diminished or altered state of consciousness, which results in impairment of cognitive abilities or physical function. The purposes of this study were to overview injury mechanism and neural plasticity of traumatic brain injury. Injury mecanism includes exitotoxicity, production free radical, inflammation and apoptosis. Furthermore traumatic brain injury has protective mechanisms includes production of neural growth factor, heat shock protein, anti-inflammatory cytokines.

• 한국의상디자인학회지
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• 제7권3호
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• pp.1-6
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• 2005

'Interaction' here means an action that reciprocally affects each other. In this action each change and movement does not exist independently but acts upon each other. The interaction of fashion design has undergone a lot of changing experiences. Besides it assumes the role of an appreciator that participates in the formation of work. This interaction breaks down the distinction between the designer as the maker and presenter of dress and the passive dresser and appreciator as its passive receivers.. Finally, it integrates the creator, receiver and technology altogether. The interaction tendencies of fashion design treated in this study are classified into four types. First, the mechanism that is included as a part of work and the cognitive response that the observer experiences. Second, the response that fashion design displays towards the stimulus of circumstances. Third, the changeability of manipulation of fashion design. Fourth, the control that mechanism acts upon dynamic status by technology. As in may other fields of our life, interaction in fashion design reflects the change and interactivity of our thinking and ideas.

• 한국과학교육학회지
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• 제31권3호
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• pp.440-454
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• 2011

This study proposes a new instructional strategy and corresponding materials designed from various alternative frameworks to help students understand evolution as a biologically acceptable theory. Biology teachers have normally taught the evolutionary mechanism by means of comparing Lamarckism with natural selection. In this study, a new instructional strategy in which the Lamarckian explanation is first excluded because Lamarckism is known to be subsumed in a learner's cognitive structure as a strong preconception of evolution is suggested for teaching evolution. After mutation theory is introduced, Darwinism including natural selection is explained separately during the next class hour. Corresponding instructional materials that aid student understanding of the evolutionary mechanism were developed using recently published articles on human genetic traits as scientific evolutionary evidence instead of the traditional evolutionary subject matter, giraffe neck. Evolutionary evidence from human genetic traits allows students to exclude anthropocentric thoughts effectively and raise concern for the phenomenon of evolution positively. The administered instructional strategy and materials in this research improved student conception, concern, and belief of evolution and it is believed that they helped students understand the evolutionary mechanism effectively.