• The Journal of Korean society of community based occupational therapy
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• v.4 no.2
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• pp.75-83
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• 2014

Objective : The purpose of this study is to find out the effects of a Home-based cognitive occupational therapy program conducted for the dementia patients in the initial stages living in Taebaek region in Gangwon-do. Methods : This study carried out Home-based cognitive occupational therapy intervention by 30 Occupational Therapy Dept. students and volunteers targeting 30 dementia patients in the initiative stages for eight sessions, once a week. To identify the change of cognitive function of the participants before and after the program, MMSE-K was used for measuring. Results : As a result of applying Home-based cognitive occupational therapy to the dementia patients in the initial stages, overall cognitive function improvement was demonstrated. Especially, statistically significant improvement was exhibited in orientation, memory retrieval, the concentration of attention, and language ability. Conclusion : The program for cognitive function improvement is considered to be usefully applied to intervention in the dementia patients. The development of various Home-based occupational therapy intervention programs is required in order to adopt the Home-based occupational therapy service in the future.

• Journal of Digital Convergence
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• v.11 no.3
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• pp.317-325
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• 2013

The purpose of this study is to evaluate the cognitive functional improvement of cognitive occupational therapy using cognitive function, activities of daily living (ADL) executive function and depression tests in community living elders with mild cognitive impairment (MCI) and dementia. Thirty two elders who diagnosed MCI (n=13) and dementia (n=19) were enrolled in this study. They visited to local elder welfare office and nursing care home from Feb. 2012 to Jun. 2012. They received occupational activity program in terms of physical activity, cognitive function and occupational function of Craft as the manner of a session per week for 8 weeks. The cognitive function, executive function, depression score were improved in both group. Furthermore in MCI participants, cognitive function scores for concentration and memory functions were significant improved more than dementia subjects. Further studies dealing with the development of novel occupational program for cognitive function improvement and its preventive effects were needed.

• Nutrition Research and Practice
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• v.17 no.2
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• pp.192-205
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• 2023

BACKGROUND/OBJECTIVES: It is known that the renin-angiotensin system (RAS) in the brain could regulate cognitive functions as well as blood pressure. Inhibition of RAS for the improvement of cognitive function may be a new strategy, but studies so far have mostly reported on the effects of RAS inhibition by drugs, and there is no research on cognitive improvement through RAS inhibition of food ingredients. Therefore, this study investigated the effect of curcumin on blood pressure and cognitive function and its related mechanism in spontaneously hypertensive rat/Izm (SHR/Izm). MATERIALS/METHODS: Six-week-old SHR/Izm rats were divided into 5 groups: control group (CON), scopolamine group (SCO, drug for inducing cognitive deficits), positive control (SCO and tacrine [TAC]), curcumin 100 group (CUR100, SCO + Cur 100 mg/kg), and curcumin 200 group (CUR200, SCO + Cur 200 mg/kg). Changes in blood pressure, RAS, cholinergic system, and cognitive function were compared before and after cognitive impairment. RESULTS: The SCO group showed increased blood pressure and significantly reduced cognitive function based on the y-maze and passive avoidance test. Curcumin treatments significantly improved blood pressure and cognitive function compared with the SCO group. In both the CUR100 and CUR200 groups, the mRNA expressions of angiotensin-converting enzyme (ACE) and angiotensin II receptor type1 (AT1), as well as the concentrations of angiotensin II (Ang II) in brain tissue were significantly decreased. The mRNA expression of the muscarinic acetylcholine receptors (mAChRs) and acetylcholine (ACh) content was significantly increased, compared with the SCO group. CONCLUSIONS: The administration of curcumin improved blood pressure and cognitive function in SCO-induced hypertensive mice, indicating that the cholinergic system was improved by suppressing RAS and AT1 receptor expression and increasing the mAChR expression.

• Korean Journal of Biological Psychiatry
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• v.9 no.2
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• pp.120-128
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• 2002

Objectives:The purpose of this study was to develop a cognitive rehabilitation program and to investigate the effect of the program that restores the deficiency of memory, which is necessary to operate on high cognitive function such as problem-solving or judgement, for TBI(traumatic brain injury) patients. Methods:Sixteen TBI patients participated in this study. The inclusion criteria were : 1) aged 18 to 60 ; 2) higher than IQ 80 ; 3) lower than MMSE-K 25 and K-MAS(Korean version of Memory Assessment Scale) 85. We administered our program to an experimental group(N=8) in order to improve attention and memory for 4 weeks(total 12 section). Our program was not administrated to a control group(N=8) for 4 weeks. After administrating this program, we measured MMSE-K and K-MAS for the experimental and control groups. Results:The findings of the study were as follows. 1) the experimental group showed significant improvement on MMSE-K score in comparison with baseline, but the control group did not. 2) the experimental group showed significant improvement on K-MAS score in comparison with baseline, but the control group did not. In particular, among the three subscales of K-MAS, only verbal memory scale revealed significant improvement, while visual and short-term memory scales revealed no differences. Conclusion:Our cognitive rehabilitation program improves cognitive state and memory, particulary verbal memory, for TBI patients. These results imply that our program aids in rehabilitation of basic cognition such as memory which is necessary to operate on high cognitive function such as problem-solving or judgement, for TBI(traumatic brain injury) patients.

• Journal of Korean Elementary Science Education
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• v.38 no.3
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• pp.360-374
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• 2019

The purpose of this study is to investigate the self-perceptions of the elementary school students' on the affective, behavioral and cognitive domains in science class. To see if there are differences in students' perceptions according to grade levels, a self-perception questionnaire was applied to third and fifth grade students in Seoul, Korea. The major results of the study are as follows. First, the perception level of the affective domain was higher than that of the cognitive domain in third grade students. There was no significant difference in the self-perception level of the fifth grade students. Both third and fifth grade students perceived the greatest improvement in the cognitive domain through one year of science teaching. Second, in the life science class, the same tendency was also observed. The students in the third and fifth grade reported that cognitive domains were the most improved through the one-year life science class. Third, when the students' perceptions were compared by grades, the third grade students showed higher self-perception scores than fifth grade students. As the grade increased, the perception scores of the students' lowered. Based on these findings, implications for science education research and teaching and learning at school are discussed.

• Journal of Ginseng Research
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• v.35 no.4
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• pp.457-461
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• 2011

A 24-week randomized open-label study with Korean red ginseng (KRG) showed cognitive benefits in patients with Alzheimer's disease. To further determine long-term effect of KRG, the subjects were recruited to be followed up to 2 yr. Cognitive function was evaluated every 12 wk using the Alzheimer's Disease Assessment Scale (ADAS) and the Korean version of the Mini Mental Status Examination (K-MMSE) with the maintaining dose of 4.5 g or 9.0 g KRG per d. At 24 wk, there had been a significant improvement in KRG-treated groups. In the long-term evaluation of the efficacy of KRG after 24 wk, the improved MMSE score remained without significant decline at the 48th and 96th wk. ADAS-cog showed similar findings. Maximum improvement was found around week 24. In conclusion, the effect of KRG on cognitive functions was sustained for 2 yr follow-up, indicating feasible efficacies of long-term follow-up for Alzheimer's disease.

• Journal of Physiology & Pathology in Korean Medicine
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• v.36 no.1
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• pp.18-22
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• 2022

To investigate effects of cognitive function improvement whether against Taegeuk ginseng on scopolamine-induced memory impairment in rats. All experiments were conducted in three groups: the control group (CTR), the scopolamine 0.4mg/kg (SCP), and the scopolamine (SCP+T) treated with Taegeuk ginseng 100 mg/kg. Taegeuk ginseng 100 mg/kg daily was orally administered for one month and treated with scopolamine was only for 7 consecutive days on the Morris water maze task. 3 weeks after oral administration of Taegeuk ginseng, subjects were performed the Morris water maze test for 8 days and then the open-field exploration test which to assessed for cognitive function improvement. After behavioral testing, subjects were sacrificed and microdissected brains for neurochemical analysis. In the cognitive-behavioral test, long-term administration of Taegeuk ginseng improved spatial navigation learning task compared with the impeded by scopolamine treatment. In neurochemistry, the expression of the synaptic marker PSD95 (postsynaptic density protein 95) was increased in the hippocampus compared to the scopolamine group. Also, brain-derived neurotrophic factor (BDNF) expression was significantly increased in the taegeuk ginseng administration group. These data suggested that long-term administration of taegeuk ginseng might improve cognitive-behavioral functions on hippocampal related spatial learning memory, and it was correlated with neurotropic and synaptic reinforcement. In conclusion, treatment with taegeuk ginseng may positive outcome on learning and memory deficit disorders.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.4 no.3
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• pp.289-304
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• 2010

This paper proposes a novel scheme for cooperative spectrum sensing on distributed cognitive radio networks. A fuzzy logic rule - based inference system is proposed to estimate the presence possibility of the licensed user's signal based on the observed energy at each cognitive radio terminal. The estimated results are aggregated to make the final sensing decision at the fusion center. Simulation results show that significant improvement of the spectrum sensing accuracy is achieved by our schemes.

• Journal of Korean Clinical Health Science
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• v.10 no.2
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• pp.1600-1606
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• 2022

Objective: This study was to compares and analyzes programs applied to improve cognitive function in patients with mild cognitive impairment and early dementia in the community to find out their effectiveness. Methods: In this study, 12 papers were finalized by searching for "elderly", "cognitive", "community", and "program" using the database of the Research Information System (RISS), National Assembly Library, and Korean Studies Information (KISS). Results: Programs for cognitive function were in the order of cognitive stimulation program, arts and crafts, and exercise program. In the program, rather than applying the cognitive stimulation program alone, the program was operated by combining leisure or exercise, music, art, and handicraft. The time was shown to be 30 minutes. The most frequently used evaluation tool was MMSE, followed by GDS and BBS. By cognitive domain, cognitive stimulation program and memory, satisfaction in psychology, and balance ability in exercise were evaluated the most. In the cognitive area, various cognitive stimulation areas were included, and in the exercise area, basic exercise, muscle strength exercise, joint exercise, and balance exercise were applied. Conclusion: Therefore, developing a program to improve cognitive function for mild cognitive impairment, it will be possible to prepare guidelines to establish and development.

• Journal of the Korean Society of Physical Medicine
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• v.19 no.2
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• pp.65-73
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• 2024

PURPOSE: This study examined the effects of kinesio taping of tibialis anterior combined with cognitive dual-task training on balance and gait ability in post-stroke patients. METHODS: This study was a single-blinded, randomized control design. Thirty post-stroke patients were allocated randomly to two groups: 1) kinesio taping of tibialis anterior combined with cognitive dual-task training (KTCDT group, n = 15) and cognitive dual-task training (Control group, n = 15). Both groups were given training for 30 minutes, five days a week for four weeks. The Berg balance test and timed up-and-go test were used to measure the balance ability. GaitRite was used to analyze the gait ability. RESULTS: Both groups showed significant improvements in balance and gait ability. The KTCDT group showed significantly greater improvement in balance ability after four weeks than the control group (p < .05). In addition, the KTCDT group showed significantly greater improvement in gait ability after four weeks compared to the control group (p < .05). CONCLUSION: Kinesio taping of the tibialis anterior combined with cognitive dual-task training effectively improves the balance and gait abilities in post-stroke patients.