• Journal of The Korean Astronomical Society
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• 제48권2호
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• pp.155-164
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• 2015

In Kang (2015) we calculated the acceleration of cosmic-ray electrons at weak spherical shocks that are expected to form in the cluster outskirts, and estimated the diffuse synchrotron radiation emitted by those electrons. There we demonstrated that, at decelerating spherical shocks, the volume integrated spectra of both electrons and radiation deviate significantly from the test-particle power-laws predicted for constant planar shocks, because the shock compression ratio and the flux of inject electrons decrease in time. In this study, we consider spherical blast waves propagating through a constant density core surrounded by an isothermal halo with ρ ∝ r⁻ⁿ in order to explore how the deceleration of the shock affects the radio emission from accelerated electrons. The surface brightness profile and the volumeintegrated radio spectrum of the model shocks are calculated by assuming a ribbon-like shock surface on a spherical shell and the associated downstream region of relativistic electrons. If the postshock magnetic field strength is about 0.7 or 7 µG, at the shock age of ∼ 50 Myr, the volume-integrated radio spectrum steepens gradually with the spectral index from α_inj to α_inj + 0.5 over 0.1–10 GHz, where α_inj is the injection index at the shock position expected from the diffusive shock acceleration theory. Such gradual steepening could explain the curved radio spectrum of the radio relic in cluster A2266, which was interpreted as a broken power-law by Trasatti et al. (2015), if the relic shock is young enough so that the break frequency is around 1 GHz.

• Journal of Microbiology
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• 제42권2호
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• pp.80-86
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• 2004

Pulsed-field gel electrophoresis (PFGE) typing was applied to the epidemiological investigation of 21 Candida tropicalis isolates collected from urine specimens of 11 patients and one healthcare worker, in an intensive care unit (ICU) over a 4-month period. Seventeen epidemiologically unrelated strains from 14 patients were also tested to determine the discriminatory power of PFGE. PFGE typing consisted of electrophoretic karyotyping (EK) and restriction endonuclease analysis of genomic DNA (REAG), using two restriction enzymes (BssHII and SfiI). The EK pattern was the same in all 38 isolates, while REAG using SfiI separated the isolates into nine types. However, 16 different PFGE types were iden-tified by REAG with BssHII, and the same results were obtained when the results of both REAG tests were combined. In serial urinary isolates from 10 patients, all strains from each patient had the same PFGE pattern. While the epidemiologically unrelated strains from 14 patients consisted of 13 different PFGE types, the 20 isolates from the 11 ICU patients fell into only two PFGE types (types Cl and C2), and these apparently originated from the two different outbreaks. All strains of type Cl (n = 12) were isolated from six patients, between November 1999 and January 2000, and all of the type C2 strains (n=8) were isolated from five patients, during January and February 2000. This study shows two con-secutive clusters of C. tropicalis candiduria in an ICU, defined by PFGE typing, and also demonstrates that a PFGE typing method using BssHII is perhaps the most useful method for investigating C. tropi-calis candiduria.

• Journal of the Korea Convergence Society
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• 제8권4호
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• pp.67-77
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• 2017

The purpose of this study is to find convergence differences of academic burnout, career preparation behavior, and general characteristics of the students majoring in medical records according to each cluster of resilience, and draw a proper improvement plan. A self-administered questionnaire survey had been conducted and a total of 168 copies were analyzed. As a results Cluster analysis was conducted on three detailed categories of resilience and was classified into two clusters. Cluster1 was a group that had points higher than the average points of Korean in each one of three categories. Cluster2 had all of which were lower points than that. Cluster1 had higher points than cluster2 in terms of career preparation behavior, hobby, subjectively good health condition, extroverted personality, good academic records, satisfaction with school life, and study satisfaction ratio, but had lower points than cluster2 in terms of academic burnout. Therefore, positiveness enhancement education focused on cluster2 will improve total group resilience.

• Translational and Clinical Pharmacology
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• 제25권3호
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• pp.147-152
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• 2017

This study focused on the role of cytochrome P450 2D6 (CYP2D6) genotypes to predict phenotypes in the metabolism of dextromethorphan. CYP2D6 genotypes and metabolic ratios (MRs) of dextromethorphan were determined in 201 Koreans. Unsupervised clustering algorithms, hierarchical and k-means clustering analysis, and color visualizations of CYP2D6 activity were performed on a subset of 130 subjects. A total of 23 different genotypes were identified, five of which were observed in one subject. Phenotype classifications were based on the means, medians, and standard deviations of the log MR values for each genotype. Color visualization was used to display the mean and median of each genotype as different color intensities. Cutoff values were determined using receiver operating characteristic curves from the k-means analysis, and the data were validated in the remaining subset of 71 subjects. Using the two highest silhouette values, the selected numbers of clusters were three (the best) and four. The findings from the two clustering algorithms were similar to those of other studies, classifying $^*5/^*5$ as a lowest activity group and genotypes containing duplicated alleles (i.e., $CYP2D6^*1/^*2N$) as a highest activity group. The validation of the k-means clustering results with data from the 71 subjects revealed relatively high concordance rates: 92.8% and 73.9% in three and four clusters, respectively. Additionally, color visualization allowed for rapid interpretation of results. Although the clustering approach to predict CYP2D6 phenotype from CYP2D6 genotype is not fully complete, it provides general information about the genotype to phenotype relationship, including rare genotypes with only one subject.

• The Bulletin of The Korean Astronomical Society
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• 제44권1호
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• pp.37.2-37.2
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• 2019

Recent investigations of the double red clump in the color-magnitude diagram of the Milky Way bulge cast serious doubts on the structure and formation origin of the outer bulge. Unlike previous interpretation based on an X-shaped bulge, stellar evolution models and CN-band observations have suggested that this feature is another manifestation of the multiple stellar population phenomenon observed in globular clusters (GCs). This new scenario requires a significant fraction of the outer bulge stars with chemical patterns uniquely observed in GCs. Here we show from homogeneous high-quality spectroscopic data that the red giant branch stars in the outer bulge ($>5.5^{\circ}$ from the Galactic center) are clearly divided into two groups according to Na abundance in the [Na/Fe] - [Fe/H] plane. The Na-rich stars are also enhanced in Al, while the differences in O and Mg are not observed between the two Na groups. The population ratio and the Na and Al differences between the two groups are also comparable with those observed in metal-rich GCs. Since these chemical patterns and characteristics are only explained by stars originated in GCs, this is compelling evidence that the outer bulge was mostly assembled from disrupted proto-GCs in the early history of the Milky Way. We will also discuss the implications of this result on the formation of the early-type galaxies in general.

• The Journal of the Korea Contents Association
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• 제21권10호
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• pp.656-667
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• 2021

Purpose: The purpose of this study was to explore the resilience experience and to identify in-depth the meaning of the resilience of newly graduated nurses. Methods: This study was a qualitative study using phenomenological research method and used data obtained from semi-structured in-depth interviews with 9 newly graduated nurses under 12 months of employment in tertiary general hospitals. The data were analyzed using Colaizzi's method. Results: As a result of analyzing the experiences of newly graduated nurses' resilience, there were totally 86 meaningful statements, 13 themes were derived from them, and they were integrated into 4 theme clusters. The four theme clusters were 'Acknowledging shortcomings and developing oneself', 'Enduring and tolerating', 'Support from people around oneself', and 'Freshening and sublimating oneself'. Conclusion: Understanding and enhancing the resilience of new nurses will help them improve nursing professionalism and reduce turnover due to reduced work stress.

• Journal of Korean Society on Water Environment
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• 제27권6호
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• pp.794-803
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• 2011

Self Organizing Map (SOM) was applied for pattern classification of hydrological and water quality data measured at Jangseong Reservoir on a monthly basis. The primary objective of the present study is to understand better data characteristics and relationship between the data. For the purpose, two SOMs were configured by a methodologically systematic approach with appropriate methods for data transformation, determination of map size and side lengths of the map. The SOMs constructed at the respective measurement stations for water quality data (JSD1 and JSD2) commonly classified the respective datasets into five clusters by Davies-Bouldin Index (DBI). The trained SOMs were fine-tuned by Ward's method of a hierarchical cluster analysis. On the one hand, the patterns with high values of standardized reference vectors for hydrological variables revealed the high possibility of eutrophication by TN or TP in the reservoir, in general. On the other hand, the clusters with low values of standardized reference vectors for hydrological variables showed the patterns with high COD concentration. In particular, Clsuter1 at JSD1 and Cluster5 at JSD2 represented the worst condition of water quality with high reference vectors for rainfall and storage in the reservoir. Consequently, SOM is applicable to identify the patterns of potential eutrophication in reservoirs according to the better understanding of data characteristics and their relationship.

• Animal Bioscience
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• 제35권6호
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• pp.826-837
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• 2022

Objective: Cambodia is located within the distribution range of the red junglefowl, the common ancestor of domestic chickens. Although a variety of indigenous chickens have been reared in Cambodia since ancient times, their genetic characteristics have yet to be sufficiently defined. Here, we conducted a large-scale population genetic study to investigate the genetic diversity and population genetic structure of Cambodian indigenous chickens and their phylogenetic relationships with other chicken breeds and native chickens worldwide. Methods: A Bayesian phylogenetic tree was constructed based on 625 mitochondrial DNA D-loop sequences, and Bayesian clustering analysis was performed for 666 individuals with 23 microsatellite markers, using samples collected from 28 indigenous chicken populations in 24 provinces and three commercial chicken breeds. Results: A total of 92 haplotypes of mitochondrial D-loop sequences belonging to haplogroups A to F and J were detected in Cambodian chickens; in the indigenous chickens, haplogroup D (44.4%) was the most common, and haplogroups A (21.0%) and B (13.2%) were also dominant. However, haplogroup J, which is rare in domestic chickens but abundant in Thai red junglefowl, was found at a high frequency (14.5%), whereas the frequency of haplogroup E was considerably lower (4.6%). Population genetic structure analysis based on microsatellite markers revealed the presence of three major genetic clusters in Cambodian indigenous chickens. Their genetic diversity was relatively high, which was similar to findings reported for indigenous chickens from other Southeast Asian countries. Conclusion: Cambodian indigenous chickens are characterized by mitochondrial D-loop haplotypes that are common to indigenous chickens throughout Southeast Asia, and may retain many of the haplotypes that originated from wild ancestral populations. These chickens exhibit high population genetic diversity, and the geographical distribution of three major clusters may be attributed to inter-regional trade and poultry transportation routes within Cambodia or international movement between Cambodia and other countries.

• The Bulletin of The Korean Astronomical Society
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• 제46권2호
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• pp.70.1-70.1
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• 2021

We examine the HI gas kinematics and distributions of galaxy pairs in group or cluster environments from high-resolution Australian Square Kilometer Array Pathfinder (ASKAP) WALLABY pilot observations. We use 32 well-resolved close pair galaxies from the Hydra, Norma, and NGC 4636, two clusters and a group of which are identified by their spectroscopy information and additional visual inspection. We perform profile decomposition of HI velocity profiles of the galaxies using a new tool, BAYGAUD which allows us to separate a line-of-sight velocity profile into an optimal number of Gaussian components based on Bayesian MCMC techniques. Then, we construct super profiles via stacking of individual HI velocity profiles after aligning their central velocities. We fit a model which consists of double Gaussian components to the super profiles, and classify them as kinematically cold and warm HI gas components with respect to their velocity dispersions, narrower or wider 𝜎, respectively. The kinematically cold HI gas reservoir (M_cold/M_HI) of the paired galaxies is found to be relatively higher than that of unpaired control samples in the clusters and the group, showing a positive correlation with the HI mass in general. Additionally, we quantify the gravitational instability of the HI gas disk of the sample galaxies using their Toomre Q parameters and HI morphological disturbances. While no significant difference is found for the Q parameter values between the paired and unpaired galaxies, the paired galaxies tend to have larger HI asymmetry values which are derived using their moment0 map compared to those of the non-paired control sample galaxies in the distribution.

• Monthly Notices of the Royal Astronomical Society
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• 제491권2호
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• pp.2268-2279
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• 2020

It is known observationally that the major axes of galaxy clusters and their brightest cluster galaxies are roughly aligned with each other. To understand the origin of the alignment, we identify 40 cluster-sized dark matter (DM) haloes with masses higher than 5 × 10¹³ M_⊙ and their central galaxies (CGs) at z ≈ 0 in the Horizon-AGN cosmological hydrodynamical simulation. We trace the progenitors at 50 different epochs between 0 < z < 5. We then fit their shapes and orientations with a triaxial ellipsoid model. While the orientations of both DM haloes and CGs change significantly due to repeated mergers and mass accretions, their relative orientations are well aligned at each epoch even at high redshifts, z > 1. The alignment becomes tighter with cosmic time; the major axes of the CGs and their host DM haloes at present are aligned on average within ~30° in the 3D space and ~20° in the projected plane. The orientations of the major axes of DM haloes on average follow one of the eigenvectors of the surrounding tidal field that corresponds to the slowest collapsing (or even stretching) mode, and the alignment with the tidal field also becomes tighter. This implies that the orientations of CGs and DM haloes at the present epoch are largely imprinted in the primordial density field of the universe, whereas strong dynamical interactions such as mergers are important to explain their mutual alignment at each epoch.