• Journal of Society of Preventive Korean Medicine
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• v.20 no.2
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• pp.77-86
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• 2016

Objectives : This study aims to investigate the current situation of domestic patents in Korea on natural products and to provide directions for developing and applying herbal medicinal products by in-depth analyses. Methods : Combinations of words, such as "A61K" or "A61P", "herb" or "Korean medicinal herb" or "Korean medicine" or "traditional" or "natural" or "$botanic^*$" or "China", and "medicine" or "treatment" or "prevention" or "improvement", were used to search patents in the World Intellectual Property Service (WIPS) database. Three methods were applied to analyze natural products patents. First, the number of patent registrations was sorted by year. Second, the assignees were analyzed by count and country of origin. Finally, cluster map analysis was conducted to explore frequently emerging words in natural products and the relationship amongst those words to treat corresponding diseases/technologies. Results : Results showed that, first, the total number of patents had been increasing. Among the patents, 76.4% were registered by domestic institutes/companies, and 23.6% by foreign institutes/companies. Second, USA, Japan, and China possess a considerable number of Korean patents and, therefore, domestic institutes/companies can seek joint technological development opportunities with their counterparts from those countries in the future. Finally, a total of four clusters were identified by cluster map analysis. Each of the clusters includes natural products related to diseases involving skin, aging, and blood sugar, as well as adult diseases. Conclusions : In this study, natural products patents registered in the Korean Intellectual Property Office were analyzed. The analyses results showed the kinds of natural products that had been employed for the treatment of certain diseases. However, natural products included in existing patents were minimal given that 4,174 species of indigenous plants are found in Korea. Thus, Korean institutes/companies should utilize unexplored plants to develop more value-added drugs.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.49 no.4
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• pp.295-299
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• 2004

The prices of domestic green tea products are relatively expensive and price differences within products of the same levels of quality are various. Also, there is no basic criteria on evaluation of green tea quality. To group 43 commercial green tea products into several parts by the principal component and cluster analyses, this work was done by use of 8 chemical constituents which were analyzed by NIR system. The principal component and cluster analyses revealed 8 groups. The first group included 16 products that had lower free amino acid and theanine contents. The second group included 5 products having higher free amino acid and theanine contents, but lower ash contents. The third group included 13 products showing medium values of 8 constituents. The IV group included 4 products having higher contents of moisture, free amino acids, and theanine. The V group included 1 product showing higher moisture but lower catechins contents. The VI group included 2 products that had higher moisture and catechins contents, but lower free amino acid and theanine contents. The VII group had higher moisture and catechins contents. The VIII group had higher ash and vitamin C contents. The free amino acid contents which were the most important in flavor evaluation of green tea quality did highly positively correlate with the contents of total nitrogen $(0.956^{**}),\;theanine\;(0.981^{**}),\;and\;caffeine\;(0.793^{**})$, but negatively with the contents of ash $(-0.884^{**})$. The catechins used as for functional ingredients did correlate with contents of caffeine(+) and vitamin C(-), respectively.

• Journal of the Korean Data and Information Science Society
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• v.21 no.6
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• pp.1211-1224
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• 2010

The study derives various anticipated benefits resulting from locating small and medium sized IT service firms in a specific industrial cluster area. The study also derives IT service agility factors to obtain competitive advantages vital to real-time global enterprises. The anticipated benefits were then used to analyze how they improve the firms' agility. Using questionnaire data, factor analyses were used to figure out eight anticipated benefit factors including coordination, information sharing, business costs, speciality, communication, trust improvement, mutual business understanding, and reciprocity. The eight empirically derived benefit factors were then used to examine how they affect the IT service agility including flexibility, speed, responsiveness, and lean efficiency. The results of regression analyses showed that each one of the anticipated benefit factors except communication influence one or more IT service agility factors.

• Animal Systematics, Evolution and Diversity
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• v.7 no.2
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• pp.179-188
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• 1991

In order to determine the taxonomic status of Apodemus agrarius chejuensis from Cheju island in Korea, three hundred and eleven samples of eight subspecies of striped field mice (subspecies, agrarius, ningpoensis , pallidior, chevrieri, insulaemus, manchuricus, coreae, and chejuensis of A. agrarius Pallas) in Asia, collected from Turkey , China, Taiwan, , Manchuria, and Koarea, were used. Four external and 27 cranial characters were measured and their measurements were utilized for multivariate analyses such as cluster, principal component, and discriminant analyses. Four forms were revealed . A largest-size from was chejuensis, whereas a large-size form was cheverieri. A medium -size from and a small-size from were coreae and other five subspecies (agrarius , ningpoensis, pallidior, insulaemus, and manchuricus) , respecitvley, but their differences were clinal. A discontinuous gap was revealed between chejuensis (a largest-size from) and six subspecies ( a medium-size from and a small-size form) Although chejuensis appeared to be a distinct species, it is concluded that molecular analyses are necessary in order to describe it as a new species.

• ALGAE
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• v.17 no.1
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• pp.59-68
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• 2002

A phylogenetic affinity between charophytes and embryophytes (land plants) has been explained by a few chloroplast genomic characters including gene and intron (Manhart and Palmer 1990; Baldauf et al. 1990; Lew and Manhart 1993). Here we show that a charophyte, Spirogyra maxima, has the largest operon of angiosperm chloroplast genomes, rpl23 operon (trnⅠ-rpl23-rpl2-rps19-rpl22-rps3-rpl16-rpl14-rps8-infA-rpl36-rps11-rpoA) containing both embryophyte introns, rpl16.i and rpl2.i. The rpl23 gene cluster of Spirogyra contains a distinct eubacterial promoter sequence upstream of rpl23, which is the first gene of the green algal rpl23 gene cluster. This sequence is completely absent in angiosperms but is present in non-flowering plants. The results imply that, in the rpl23 gene cluster, early charophytes had at least two promoters, one upstream of trnⅠ and and another upstream of rpl23, which partially or completely lost its function in land plants. A comparison of gene clusters of prokaryotes, algal chloroplast DNAs and land plant cpDNAs indicated a loss of numerous genes in chlorophyll a+b eukaryotes. A phylogenetic analysis using presence/absence of genes and introns as characters produced trees with a strongly supported clade containing chlorophyll a+b eukaryotes. Spirogyra and embryophytes formed a clade characterized by the loss of rpl5 and rps9 and the gain of trnⅠ (CAU) and introns in rpl2 and rpl16. The analyses support the hypothesis that the rpl23 gene cluster and the rpl2 and rpl16 introns of land plants originated from a common ancestor of Spirogyra and land plants.

• The Korean Journal of Zoology
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• v.38 no.3
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• pp.324-329
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• 1995

The phylogenetic relationships between Cheju native horses and Tsushima native horses were studied by protein polymorphism analyses in 16 gene loci (Trypsin inhibitor: Ti, Chymotrypsin inhibitor: CTi, Albumin: Al, Esterase: Es, Transferrin: Tf, Hemoglobin: Hb, Catalase: Cat, Esterase D: EsD, Glutamate oxaloacetate transaminase: GOT, Glyoxalase I: GLO I, Acid phosphatase: AcP, Superoxide dismutase: SOD, Lactate dehydrogenase: LDH, Hexokinase: HK, Malate dehydrogenase: MDH, Malic enzyme: ME). All allelic patterns of the protein loci, except 5 loci (SOD, LDH, HK, MDH, ME), were polymorphic in both two populations. Gene frequencies of the polymorphic loci of the population of Cheju native horses were higher than those of Tsushima native horses. Average heterozygosity in Cheju native horses was 0.375, showing higher than that of Tsushima native horses (0.304). The Da distance and gene identity of two populations were 0.108 and 0.868, respectively. The phylogenetic tree constructed by these results and those previously reported in other horse populations, consisted of three clusters. From this phylogenetic tree, it could be suggested that Cheju native horses and Tsushima native horses had diverged from the Mongolian wild horse (Equus prsewolskii).

• Journal of the East Asian Society of Dietary Life
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• v.24 no.6
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• pp.915-923
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• 2014

This study investigated organic coffee choice motives from a coffee shop market segmentation perspective in order to understand the potential importance they may have upon attitudes and behavioral intentions to buy organic coffee. A factor-cluster segmentation approach was used for this study. An exploratory factor analysis identified five organic coffee choice motives: 'Sensory', 'Environment', 'Trust', 'Health' and 'Price'. Based upon these five choice motives, cluster analyses classified all respondents into three homogeneous subgroups: 'Highly motivated', 'Moderately motivated' and 'Unmotivated'. Analysis of variance tests indicated that attitudes and intentions to purchase organic coffee were significantly different among the three clusters. In particular, two cluster groups representing 'Highly motivated' and 'Moderately motivated' were found to offer the most utility for further organic coffee market segmentation research. Especially, due to perceptions about high price premium of organic coffee, the 'Moderately motivated' group had higher positive attitudes, although, their intentions to buy organic coffee were not higher than those of the 'Unmotivated' cluster. Findings support previous research propositions that high price could be the strongest barrier for people to purchase organic products including the organic coffee business context. This will assist to market and promote pricing strategies for caf$\acute{e}$s and restaurants to optimize organic coffee sales revenue. Implications for all cluster groups regarding unique socio-demographic characteristics and behavioral intentions are discussed. Organic coffee marketers can apply these findings towards the development of effective target market strategies.

• World Technopolis Review
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• v.1 no.3
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• pp.177-185
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• 2012

In recent years, some experts have shown that urban competitiveness is more important than national competitiveness. They have also argued that innovation will make cities more competitive. The purpose of this paper is to create Korean urban competitiveness index, and to also highlight strategic aspects for enhancement of urban competitiveness of metropolitan cities based on innovation in Korea. First, we will present various factors and indicators of urban competitiveness based on three components for innovation: formation of cluster, human capital, creative economy. Available literature and statistical analyses will be used. Second, scores of urban competitiveness will be developed based on Analytic Hierarchy Process (AHP). Evaluation of scores with weights will be used for this purpose. The resulting weights are 0.3672 for the formation of cluster, 0.3318 for human capital, and 0.3010 for creative economy, respectively. Finally, we present urban competitiveness using the standardized T-score. The most competitive city based on innovation is Daejeon(1st), followed by Gwangju(2nd) and Daegu(3rd). Three least competitive cities are Incheon (6th), Busan(5th) and Ulsan(4th).

• Journal of The Korean Astronomical Society
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• v.37 no.5
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• pp.605-609
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• 2004

We present a set of high-resolution 3D MHD simulations exploring the evolution of light, supersonic jets in cluster environments. We model sets of high- and low-Mach jets entering both uniform surroundings and King-type atmospheres and propagating distances more than 100 times the initial jet radius. Through complimentary analyses of synthetic observations and energy flow, we explore the detailed interactions between these jets and their environments. We find that jet cocoon morphology is strongly influenced by the structure of the ambient medium. Jets moving into uniform atmospheres have more pronounced backflow than their non-uniform counterparts, and this difference is clearly reflected by morphological differences in the synthetic observations. Additionally, synthetic observations illustrate differences in the appearances of terminal hotspots and the x-ray and radio correlations between the high- and low-Mach runs. Exploration of energy flow in these systems illustrates the general conversion of kinetic to thermal and magnetic energy in all of our simulations. Specifically, we examine conversion of energy type and the spatial transport of energy to the ambient medium. Determination of the evolution of the energy distribution in these objects will enhance our understanding of the role of AGN feedback in cluster environments.

• Journal of The Korean Astronomical Society
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• v.17 no.1
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• pp.1-14
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• 1984

Analyses of an integrated form $N(\tau)={\int}_{\tau}^{\infty}n(\tau)d{\tau}$ of the distribution of cluster ages, rather than its differential form $n(\tau)$, demonstrate that the observed distribution has clusters older than about 500 million years in a significant excess over theoretical model distributions. Considerations on cluster disruption processes show that a single disruption time-scale, frequently employed by current theoretical models, is no longer an adequate parameter for describing survival probability of clusters over wide age range, because different initial conditions of these clusters produce corresponding spreads in their lifetimes. To take into account for the spread in initial conditions, we have introduced an age-dependent disruption time, and deduced its age-dependence from the present-day age distribution of clusters. Results show a distinct two-stage variation: The newly introduced disruption time stays constant at about 50 million years for clusters younger than about 100 million years, while for clusters older than that it increases monotonically with the cluster age. This leads us to conclude that clusters experience different types of disrupting causes as they get old.