• Journal of the Korean Society of Environmental Restoration Technology
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• v.9 no.3
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• pp.51-58
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• 2006

The purpose of this research presents a method to position and makes the structure for eco-corridors reasonably with collectable analysing results of various effects shown in mammals' road-kill at 429 points. Target animals of this research are Leopard cat, Siberian weasel, Raccoon dog, Korean hare, Eurasian red squirrel, Siberian chipmunk and Water deer. The results derived from the empirical analysis on the contents above are followed. First, according to the results as for Leopard cat road kill analysis, which is designated as Endangered Species Class II, the eco-corridor might be located at near village having stead food in order to decrease the frequencies of road-kill, because its road kill points were mainly collected at 4 lane hilly road with mountain-road-farm area geological type of. Second, because Siberian weasel's road kill was detected at 2 lane hilly road with mountain-road-stream geological type, the eco-corridor might be located at near a mill to decrease road-kill frequencies. Third, the road-kill frequency of Eurasian red squirrel can be reduced when the eco-corridor is located at the area across coniferous tree near 4 lane west sea freeway with mountain-road-mountain. Fourth, the road-kill of Raccoon dog can be reduced when the eco-corridor is located at 4 lane mountain road or hilly road with the geological type having farm land-road-mountain(stream). Fifth, Korean hare's road-kill can be reduced when the eco-corridor is located at grass land across ridge line of mountain, because wild rabbit road kill was happened at 4 lane mountain road or 2 lane mountain road(mountain-road-mountain). Sixth, As for Siberian chipmunk, the eco-corridor might be located at the side slope of mountain road at 2 lane mountain road under the speed of 60km/h with mountain-road-mountain. Seventh, For Water deer, the eco-corridor might be located at 4 lane hilly road with mountain-road-farm land. As for Common otter, Amur hedgehog, Yellow-throated marten, Weasel, it is difficult to specify the proper site of eco-corridor due to the lack of data. Eco-corridors for carnivores might be well located at 4 lane hilly road or 2 lane hilly road with mountain-road-farm land, and the track for herbivores might be well located as a overhead bridge on mountain-road-mountain type across mountains. In order to position eco-corridors for wildlife properly, we have to research animal's behavior with ecological background, and to consider the local uniqueness and regularly collect the empirical road-kill data in long term 3 to 5 year, which can be the foundation for the more suitable place of wild life eco-corridors.

• 한국방재학회:학술대회논문집
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• 2011.02a
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• pp.213-213
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• 2011

근래 이상기후에 의한 강우량 증대와 도시화에 따른 첨두유출량의 증대 및 도달시간의 단축은 기존의 유수지만으로 도시홍수를 대처하는데 그 한계점에 다다르게 되었다. 1990년대에 들어 각종 우수유출 저감시설의 활용으로 이상의 문제를 해결하고자 하는 노력들이 시작되었으며, 현재 신규개발지에 저류지와 같은 우수유출저감시설 설치를 법제도적으로 의무화 하고 있어, 전국적으로 천여개소의 저류지가 시설되어 있거나 계획 중에 있다. 저류지는 개발로 인해 증가된 첨두유출량을 개발전의 상태로 저감시키기 위하여 임시 또는 상시 저류하거나 저류능력 이상의 유출량에 대해서는 암거방류시설을 통해 하류부의 하천 또는 하도로 방류시키는 역할을 수행하는 수공구조물로서 일반적으로 저류지 계획 및 설계는 첨두유출량 증가분에 대해 초점을 맞추고 있을 뿐 방류시설에 대한 구체적인 설계는 이루어지지 않고 있는 실정이다. 또한 현재 국내에는 저류지 방류시설로 주로 사용되는 암거에 관한 설계규정이나 기법은 미미한 상태로, 한국도로공사(1991)에서 발표한 "도로배수계획"을 이용하고 있으며, 이는 미국 연방도로국(FHWA, 1985)에서 발표한 설계기법을 그대로 인용하고 있다. 즉, 지형 또는 현장 여건에 따라 암거 흐름의 8형식 중 하나의 형식으로 결정하고, 그 형식에 따라 관련도표를 이용한 시산법 또는 도식해법을 적용하여 유입부 상류수위를 산정함으로써 암거설계가 이루어진다. 하지만 이러한 암거설계 방식은 도로 배수암거에 적합한 것으로 저류지 배수암거에 적용하기에는 무리가 있다고 본다. 따라서, 본 연구에서는 저류지의 일반적인 특성상 암거흐름 8형식 중 Class-II군의 암거 상류부 수위가 잠수된 조건 즉, 평상시 저류지가 일정수위 이상의 저류량을 유지하고 있는 상태에서 저류지 암거방류시설의 대표적인 설계인자인 암거직경, 암거경사, 암거경사, 하류단 수위조건의 변화에 따른 상류부 수위변화를 유량별로 분석해 보았다. 방류 암거의 개수를 고려하기 위하여 암거상류부 수위와 암거직경의 관계해석 시 암거단면적을 이용하여 분석하였으며, 각각의 유량별로 상류부 수위와 암거단면적의 관계를 회귀식으로 제시하였다. 암거상류부 수위와 암거경사의 관계를 분석한 결과 암거경사가 5~20%로 변화할 때 암거상류부 수위의 변화는 2~5%정도의 매우 작은 변화를 보임을 확인할 수 있었으며, 암거길이의 경우는 해석 조건의 특성상 상류부 수위에 영향이 전혀 나타나지 않았다. 암거상류부 수위와 암거하류단 수위의 관계에서 암거상류부 수위는 암거하류단 수위가 암거직경과 퇴사위 높이의 합보다 암거하류단의 수위가 높아지는 시점부터 암거하류단 수위에 비례해서 증가되는 결과를 알 수 있었다.

• Journal of Biosystems Engineering
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• v.19 no.1
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• pp.9-16
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• 1994

135 and 136 pine cones were sampled from age class of II to VI Korean pine trees for the study of their physical properties in 1991 and 1992, respectively. The length, width, weight, volume, and the largest projected area of cones were measured, and the specific gravity, apparent volume ratio sphericity, and roundness were calculated. Regression analysis were performed for the weight, volume, and projected area to the cone length and width. The length, and major and minor diameters of the cone stalks were measured and analyzed. 1. The range of the length of cone stalks was 0 to 47.3mm. The average length of stalks were 9mm ('91) and 10mm('92), respectively. Cross section of the stalks was ellipse with average major and minor diameters of 9.1mm and 10.1mm, and 8.6 and 8.7mm in 91 and 92, respectively. 2. The length of pine cones distributed from 8cm to 17cm and the average length were about 13cm('91, '92). The width varied from 5cm to 9.5cm and the average width were 6.7cm('91) and 6.9cm('92). The ratios of the length to the width were 0.56('91) and 0.65('91) and the shape of the cones were found to be ellipse with minor diameter of 1/2 to 2/3 of the major diameter. 3. The roundnesses and sphericity of cones were 0.74 and 0.75('91), 0.63 and 0.67('92), respectively. The average of the largest projected area of cones were $85.3cm^2$('91) and $93.1cm^2$('92) and the criterion areas were $71.0cm^2$ and $74.5cm^2$, respectively. 4. Cone weights were from 83g to 467g('91 and '92) and averages were 186g('91) and 220g('92). The average specific gravities were 0.89 and 0.96('91 and '92). The true volumes were $212cm^2$('91) and $230cm^2$('92), and the average bulk volume was $321cm^2$('91, '92). The average apparent volume ratios of cones were 35% ('91) and 28% ('92), respectively. 5. The weight and the volume were proportional to the length of the cone multiplied by the width squred and the largest projected area was proportional to the length multiplied by the width of cones.

• Journal of Pharmaceutical Investigation
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• v.40 no.1
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• pp.51-57
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• 2010

Losartan potassium, 2-butyl-4-chloro-1-[p-(o-1H-tetrazol-5-ylphenyl)benzyl]imidazole-5-methanol mono-potassium salt, is a new class of antihypertensive agents, and is an antagonist in angiotensin receptor. The purpose of the present study was to evaluate the bioequivalence of two Losartan potassium tablets, Cozaar tablet (MSD Pharmaceutical Co., Ltd.) and Losata tablet (Kyung Dong Pharmaceutical Co., Ltd.), according to the guidelines of the Korea Food and Drug Administration (KFDA). The release of losartan from the two losartan potassium formulations in vitro was tested using KP VIII Apparatus II method with various dissolution media. Twenty eight healthy male subjects, $23.86{\pm}1.80$ years in age and $67.27{\pm}6.60\;kg$ in body weight, were divided into two groups and a randomized $2{\times}2$ cross-over study was employed. After a single tablet containing 50 mg as losartan potassium was orally administered, blood samples were taken at predetermined time intervals, and the concentrations of losartan in serum were determined using HPLC with fluorescence detector. The dissolution profiles of two formulations were similar in all tested dissolution media. The pharmacokinetic parameters such as $AUC_t$, $C_{max}$ and $T_{max}$ were calculated, and Equiv Test/K-BE Test 2002 was utilized for the statistical analysis of the parameters using logarithmically transformed $AUC_t$, $C_{max}$ and untransformed $T_{max}$. The results showed that the differences between two formulations based on the reference drug, Cozaar, were -2.70%, 1.45% and 2.31% for $AUC_t$, $C_{max}$ and $T_{max}$, respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log 0.8 to log 1.25 (e.g., log 0.8852~log 1.0655 and log 0.8319~log 1.2342 for $AUC_t$ and $C_{max}$, respectively). Thus, the criteria of the KFDA bioequivalence guideline were satisfied, indicating Losata tablet was bioequivalent to Cozaar tablet.

• Cartoon and Animation Studies
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• s.34
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• pp.197-217
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• 2014

The 1920s and 1930s ushered in "the golden age" of Chinese comics when the comics flourished. Satirical cartoons in modern Chinese comics were popular due to emotional instability and war caused by foreign powers. Among many popular comics, this paper analyzes in the 1920s and in the 1930s which were made into films and dramas. Chapter Two shows that China in the Republican era of China expanded its consumer culture into some sectors like films, novels, magazines and fashion in the 1920s and 1930s. However, more than any other things, this chapter considers from the historical perspective "the golden age" of comics including comic magazine in the 1930s and a history of comic magazines that gained popularity with conventional and common story. Chapter Three explains that social satire cartoons were in vogue since the May Fourth Movement and anti-imperialistic and semi-feudalistic stories in the 1920s were realized in life. It also says that comics that describes the negative sides of its society were popular. Ye QianYu, a cartoonist, portrayed many facets of Shanghai through : the daily life of the middle and lower classes, bureaucratic corruption and sympathy for the working class. drawn by Zhang LePing describes the unfair social system between the bourgeoisie and the proletariat and the gap between the rich and poor through the main character, the powerless and poor orphan. and lampooned the reality of its time in an objective, witty and humorous way in terms of ethics and economy respectively. The researcher chooses to study and which are very familiar to us, because good cartoons, animations and movies stimulate the feelings about our surroundings.

• Journal of Microbiology and Biotechnology
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• v.19 no.9
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• pp.1041-1050
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• 2009

Equine respiratory disease is a common cause of poor performance and training interruptions. The higher incidence rate of infectious upper respiratory disease (IURD) in thoroughbred racehorses at the Seoul Race Park coincided with the frequent stabling season, shorter stabling periods, and younger ages in this study. Incidence rates were also correlated with significantly lower proportions of cells expressing MHC class II-, CD2 antigen-, $CD4^+$- or $CD8^+$-T lymphocyte-, and B lymphocyte in IURD patients compared with healthy control groups in the summer and fall and in 2-and-3-year-old groups. The data suggested that movement and new environments may have resulted in immunosuppression and inappropriate responses to respiratory pathogens in IURD patients. The IURD incidence decreased with age, perhaps by the acquisition of immunity, and study results suggested that immunologic protection was associated with IURD, particularly in young thoroughbred racehorses. Streptococci isolates were identified in 11 of 72 IURD horses, and 3 of these isolates were identified as Streptococcus. equi subsp. equi. S. equi subsp. zooepidemicus was isolated from 2 of 23 IURD horses in the spring (8.7%), 5 of 23 in the summer (21.7%), and 1 of 6 in winter (16.7%). S. equi subsp. zooepidemicus (5%) was also identified in 3 of 61 isolates from clinically normal horses. Racetracks should implement anti-IURD protective measures by assessing the capacity of equine immunologic protection at the Park and by limiting the introduction of specific respiratory pathogens (such as S. equi subsp. equi) by preventing the access of infected but subclinical horses with a specified respiratory pathogen-free certification system prior to Park entry.

• Journal of Chest Surgery
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• v.49 no.3
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• pp.165-170
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• 2016

Background: In elderly high-risk surgical patients, sutureless aortic valve replacement (AVR) should be an alternative to standard AVR. The potential advantages of sutureless aortic prostheses include reducing cross-clamping and cardiopulmonary bypass (CPB) time and facilitating minimally invasive surgery and complex cardiac interventions, while maintaining satisfactory hemodynamic outcomes and low rates of paravalvular leakage. The current study reports our single-center experience regarding the early outcomes of sutureless aortic valve implantation. Methods: Between October 2012 and June 2015, 65 patients scheduled for surgical valve replacement with symptomatic aortic valve disease and New York Heart Association function of class II or higher were included to this study. Perceval S (Sorin Biomedica Cardio Srl, Sallugia, Italy) and Edwards Intuity (Edwards Lifesciences, Irvine, CA, USA) valves were used. Results: The mean age of the patients was $71.15{\pm}8.60years$. Forty-four patients (67.7%) were female. The average preoperative left ventricular ejection fraction was $56.9{\pm}9.93$. The CPB time was $96.51{\pm}41.27minutes$ and the cross-clamping time was $60.85{\pm}27.08minutes$. The intubation time was $8.95{\pm}4.19hours$, and the intensive care unit and hospital stays were $2.89{\pm}1.42days$ and $7.86{\pm}1.42days$, respectively. The mean quantity of drainage from chest tubes was $407.69{\pm}149.28mL$. The hospital mortality rate was 3.1%. A total of five patients (7.69%) died during follow-up. The mean follow-up time was $687.24{\pm}24.76days$. The one-year survival rate was over 90%. Conclusion: In the last few years, several models of valvular sutureless bioprostheses have been developed. The present study evaluating the single-center early outcomes of sutureless aortic valve implantation presents the results of an innovative surgical technique, finding that it resulted in appropriate hemodynamic conditions with acceptable ischemic time.

• Korean Journal of Ichthyology
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• v.18 no.4
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• pp.283-292
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• 2006

Expressed sequence tag (EST) analysis was conducted using a complementary DNA (cDNA) library made from the kidney mRNA of olive flounder (Paralichthys olivaceus). In the survey of 390 ESTs chosen from the kidney cDNA library, 250 ESTs showed significant homology to previously described genes while 140 ESTs were unidentified or novel. Comparative analysis of the 250 identified ESTs showed that 14 (5.6%) clones were representing 11 unique genes identified as homologous to the previously reported olive flounder ESTs, 198 (79.2%) clones representing 160 unique genes were identified as orthologs of known genes from other organisms, and orthologs were established for 38 (15.2%) clones representing 37 genes of known sequences with unknown functions. We also identified several kinds of immune associated proteins, indicating EST as a powerful method for identifying immunerelated genes of fish as well as identifying novel genes. Further studies using cDNA microarrays are needed to identify the differentially expressed transcripts after disease infection.

• Journal of The Korean Association For Science Education
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• v.25 no.3
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• pp.327-335
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• 2005

This study investigates student achievement and science-related attitudes on STS hypothetical deductive instruction strategy in the water section of high school chemistry. Two 11th grade co-ed high school classes participated in the study; one control group and one treatment group. After being taught for 10 class periods during the second semester. ANCOVA analysis revealled no significant difference (p>.05) between two groups' achievement tests. However, analysis by ANCOVA did show that the scores for science-related attitudes in the treatment group were significantly higher than those of the control group (p<.05). In particular, the scores of science learning contents and science value about science-related attitude were significantly higher in the treatment group.

• IMMUNE NETWORK
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• v.3 no.2
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• pp.103-109
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• 2003

Background: As all HLA class II genes, the DQ genes show their polymorphic variation mainly in the second exon, which encodes the first extracellular domain of the molecule. PCR-SSOP (Polymerase chain reaction-Sequence specific oligonucleotide probe) techniques were frequently used for HLA-DQA1 and DQB1 typing but certain alleles, $DQA1^*0101/0104/0105$, $^*302/0303$, $*0501/0505$ and $DQB1^*0201/^*0202$ which differ from each other in segment other than exon 2, could not be unequivocally assigned. Methods: To overcome this problem, we applied additional PCR-SSP (PCR-Sequence specific primer) method to analyze DQA1 exons 1, 3 and 4 and DQB1 exon 3. And we investigated the distributions and haplotypes of HLA-DRB1, DQA1 and DQB1 alleles in 406 unrelated Korean healthy individuals. Results: Using this method the indistinguishable alleles of DQA1 and DQB1 in PCR-SSOP were typed definitively. We also found several important associations between DQA1 and DQB1 alleles in the Korean population; $DQA1^*0101-DQB1^*0501$, $DQA1^*0104-DQB1^*0502$ or $-^*0503$, $DQA1^*0105-DQB1^*0501$, $DQA1^*0302-DQB1^*0303$, $DQA1^*0303-DQB1^*0401$ or $-^*0402$, $DQA1^*0501-DQB1^*0201$, $DQA1^*0505-DQB1^*0301$, and $DQA1^*0201-DQB1^*0202$. The haplotypes of DRB1-DQA1-DQB1 associated with $DQA1^*01$, $^*03$, $^*05$, and $DQB1^*02$ subtypes were investigated. Several haplotypes associated with these alleles were observed in the Korean population. Conclusion: Our results can be helpful to find potential unrelated donors for bone marrow registries and study the HLA-associated disease and anthropology at high-resolution allelic level.