• Proceedings of the KIPE Conference
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• 1999.07a
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• pp.643-645
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• 1999

The conventional high frequency phase-shifted full bridge dc/dc converter has a disadvantage that a circulating current flows through transformer and switching devices during the freewheeling interval. Due to this circulating current, RMS current stress, conduction losses of transformer and switching devices are increased. To alleviate this problem, this paper provides a circulating current free type high frequency soft switching phase-shifted full bridge (FB) dc/dc converter with the modified energy recovery snubber (ERS) attached at the secondary side of transforemr.

• Proceedings of the KIPE Conference
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• 1999.07a
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• pp.626-630
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• 1999

A new integrated single-stage zero current switched(ZCS) quasi-resonant converter (QRC) for the power factor correction(PFC) converter is introduced in this paper. The power factor correction can be achieved by the discontinuous conduction mode(DCM) operation of an input current. The proposed converter has the characteristics of the good power factor, low line current harmonics, and tight output regulation. Furthermore, the ringing effect due to the output capacitance of the main switch can be eliminated by use of active clamp circuit.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2006.10a
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• pp.209-210
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• 2006

• Journal of Power Electronics
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• v.2 no.3
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• pp.199-205
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• 2002

This paper compares three kinds of soft-switching circuits from viewpoints of surge suppression, load characteristic, and power efficiency for a tapped-inductor buck converter with low voltage and high current. As a result, these soft-switching techniques have achieved much higher efficiency of 80 % when compared with a hard-switching buck converter for the output condition of 1V and 20A.

• Journal of Chest Surgery
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• v.19 no.4
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• pp.549-557
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• 1986

In cardiac patients who received multidose cold blood potassium cardioplegia for intracardiac procedures, the intraoperative and the immediate postoperative blood potassium levels were decreased at aortic cross-clamp time below 2 hours and increased at aortic cross-clamp time above 2 hours, but they were within normal limit [not hypokalemia or hyperkalemia]. In spite of increased infusion numbers and amount of cold blood potassium cardioplegia, the postoperative blood potassium levels were similar to the postoperative levels, the immediate postoperative A-V blocks were transient and the postoperative arrhythmia were rare.

• Proceedings of the KIEE Conference
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• 2001.04a
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• pp.301-303
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• 2001

This paper proposes the boost input type active clamp DC-DC converter featuring the high efficiency and improved EMI characteristics. The main characteristic of the converter is to operate with the non-pulsating input and output currents. Besides, it has the zero-voltage switching (ZVS) and low voltage stress characteristics. For the proposed converter, the detailed operation principles and the simulation results are presented.

• Proceedings of the KIEE Conference
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• 2006.07b
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• pp.1235-1236
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• 2006

In this paper, we designed high performance, high quality and high density switch mode power supply for precision electronics, and communication equipments. For this, we used two parallel DC-DC converters, which have opposite phases, to support proper high performance and high quality power. To reduce switching losses and make high switching frequency, active-clamp and ZVS technique were employed in each converter.

• Proceedings of the KIEE Conference
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• 2006.07c
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• pp.1695-1696
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• 2006

In this paper, we designed high performance, high quality and high density switch mode power supply for precision electronics, and communication equipments. For this, we used two parallel DC-DC converters, which have opposite phases, to support proper high performance and high quality power. To reduce switching losses and make high switching frequency, active-clamp and ZVS technique were employed in each converter.

• The Korean Journal of Physiology and Pharmacology
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• v.22 no.6
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• pp.649-660
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• 2018

Migraine is a neurological disorder characterized by recurrent and disabling severe headaches. Although several anticonvulsant drugs that block voltagedependent $Na^+$ channels are widely used for migraine, far less is known about the therapeutic actions of carbamazepine on migraine. In the present study, therefore, we characterized the effects of carbamazepine on tetrodotoxin-resistant (TTX-R) $Na^+$ channels in acutely isolated rat dural afferent neurons, which were identified by the fluorescent dye DiI. The TTX-R $Na^+$ currents were measured in medium-sized DiIpositive neurons using the whole-cell patch clamp technique in the voltage-clamp mode. While carbamazepine had little effect on the peak amplitude of transient $Na^+$ currents, it strongly inhibited steady-state currents of transient as well as persistent $Na^+$ currents in a concentration-dependent manner. Carbamazepine had only minor effects on the voltage-activation relationship, the voltage-inactivation relationship, and the use-dependent inhibition of TTX-R $Na^+$ channels. However, carbamazepine changed the inactivation kinetics of TTX-R $Na^+$ channels, significantly accelerating the development of inactivation and delaying the recovery from inactivation. In the current-clamp mode, carbamazepine decreased the number of action potentials without changing the action potential threshold. Given that the sensitization of dural afferent neurons by inflammatory mediators triggers acute migraine headaches and that inflammatory mediators potentiate TTX-R $Na^+$ currents, the present results suggest that carbamazepine may be useful for the treatment of migraine headaches.

• The Korean Journal of Physiology and Pharmacology
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• v.10 no.3
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• pp.131-135
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• 2006

Coeruleo-vestibular pathway which connects locus coeruleus and vestibular nuclei is noradrenergic. This study was designed to elucidate the effects of phenylephrine on the spontaneous activity of acutely isolated medial vestibular nuclear neurons of rat by whole-cell patch-clamp technique. Sprague-Dawley rats, aged 14 to 16 days, were used. After enzymatic digestion, dissociated medial vestibular neurons were transferred to a recording chamber mounted on an inverted microscope, and spontaneous action potentials were recorded by standard patch-clamp techniques. In current-clamp mode, the frequency of spontaneous action potential of medial vestibular nuclear neurons was decreased by phenylephrine (n=15). Phenylephrine increased the amplitude of afterhyperpolarization without changes in the resting membrane potential and spike width. In voltage-clamp mode, the whole potassium currents of the medial vestibular nuclear neurons were increased by phenylephrine (n=12). These experimental results suggest that ${\alpha}-receptor$ mediates the inhibitory effects on the neuronal activity of the medial vestibular nuclear neuron.