• The Korean Journal of Physiology
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• v.25 no.2
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• pp.147-158
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• 1991

The effects of noradrenaline on the spontaneous contraction recorded from a strip of mucosa-free antral circular muscle were studied in the guinea-pig stomach, and the changes in slow waves and membrane resistance were analyzed in order to elucidate the mechanism for the excitatory response to noradrenaline. Electrical responses of circular muscle cells were recorded using glass microelectrodes filled with 3 M KCI. Electrotonic potentials were produced to estimate membrane resistance by the partition stimulating method. All experiments were performed in tris-buffered Tyrode solution which was aerated with 100% $O_2$ and kept at $35^{\circ}C$. The results obtained were as follows: 1) The spontaneous contractions were potentiated dose-dependently by the application of noradrenaline. 2) Through the experiments using adrenoceptor-blockers, the strong excitatory effect via $[\alpha}-adrenoceptors$ and the weak inhibitory efffect via ${\beta}-adrenoceptors$ were noted. 3) Noradrenaline produced hyperpolarization of membrane potential, and increases in the amplitude and the maximum rate of rise of slow waves. 4) In the presence of apamin, Ca-dependent K channel blocker, the characteristic hyperpolarization was not developed. However, the excitatory effect of noradrenaline on spontaneous contraction remained. 5) Membrane resistance was reduced during the hyperpolarized state by the application of noradrenaline, and the change of membrane resistance and the hyperpolarized state were completely abolished by apamin. From the above results, following conclusions could be made: Excitatory responses to noradrenaline result from the dominant ${\alpha}-excitatory$, and the weak ${\beta}-inhibitory$ action of noradrenaline. Hyperpolarization of membrane potential by noradrenaline is due to the activation of Ca-dependent K channel.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.18 no.2
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• pp.268-275
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• 2014

In this paper, a dual-band circular ring monopole antenna with stub and ground slot for WLAN(Wireless Local Area Networks)/WiMAX(World interoperability for Microwave Access) applications. The proposed antenna is based on a planar monopole design, and composed of one circular ring of radiating patch, cross strip in circular ring, modified feed line, and two rectangular slot in the ground plane for triple-band operation. To obtain the optimized parameters, we used the simulator, Ansoft's High Frequency Structure Simulator(HFSS) and found the parameters that greatly effect antenna characteristics. Using the obtained parameters, the antenna is fabricated. The numerical and experiment results demonstrated that the proposed antenna satisfied the -10 dB impedance bandwidth requirement while simultaneously covering the WLAN and WiMAX bands. And characteristics of gain and radiation patterns are determined for WLAN/WiMAX application.

• The Korean Journal of Physiology
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• v.24 no.1
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• pp.39-49
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• 1990

It has been reported that bombesin induces contraction of the smooth muscle of the gastrointestinal tract. Thus, the present investigation was undertaken to see an influence of bombesin on electrical activity of the gastric smooth muscle, since electrical activity is associated with contractile activity in the smooth muscle of the stomach. Smooth muscle strips $(5\;{\times}\;1.5\;cm)$ that included the corpus and antrum were prepared from the ventral and dorsal portion of the feline stomach along the greater curvature. Circular muscle strips $(1\;{\times}\;0.3\;cm)$ of the corpus were also obtained. Electrical activity of the corpus and antrum of the muscle strip was monophasically recorded by using Ag-AgCl capillary electrodes placed on the circular muscle layer. Contractile activity of the circular muscle strip was also recorded. The recordings were performed in Krebs-Ringer solution that was continuously aerated with $O_{2}$ containing 5% $Co_{2}$, and kept at $36^{\circ}C$. Dose-related responses of electrical activity and contractility to bombesin was studied after frequency of slow waves and contraction of each strip reached to a steady state. An action of $D-leu^{13}-{\psi}\;(CH_{2}NH)-D-leu^{14}-bombesin,\;D-pro^{2}-D-trp^{7,9}-substance\;P$, tetrodotoxin, hexamethonium, atropine, phentolamine or propranolol on the effect of bombesin was also observed. 1) Bombesin increased frequency of slow waves and contractions dose-dependently at concentrations from $10^{-9}\;M\;to\;3\;{\times}\;10^{-8}\;M$. 2) The bombesin analogue at a concentration of $3\;{\times}\;10^{-7}\;M$ antagonized the effect of bombesin on frequency of slow waves. 3) The effect of bombesin on frequency of slow waves was inhibited by tetrodotoxin $(10^{-6}\;M)$ and hexamethonium $(10^{-3}\;M)$ but unaffected by atropine $(10^{-6}\;M)$, phentolamine $(10^{-5}\;M)$ and propranolol $(10^{-5}\;M)$. 4) The effect of bombesin on frequency of slow waves was blocked by the substance P analogue at a concentration of $10^{-5}\;M$. 5) Substance P at a concentration of $10^{-5}\;M$ failed to change frequency of slow waves. It is concluded from the above results that bombesin increases the frequency of slow waves as well as contractions of the smooth muscle strip from the feline stomach, and the effect of bombesin might be mediated by non-cholinergic or non-adrenergic mechanism at neuromuscular junction. However, enteric nerves that have substance P as a neurotransmitter do not appear to participate in the action of bombesin on frequency of slow waves.

• The Korean Journal of Physiology and Pharmacology
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• v.4 no.3
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• pp.227-234
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• 2000

Many reports suggest that neurotensin (NT) in the gastrointestinal tract may play a possible role as a neurotransmitter, a circulating hormone, or a modulator of motor activity. NT exerts various actions in the intestine; it produces contractile and relaxant responses in intestinal smooth muscle. This study was designed to investigate the effect of NT on motility of antral circular muscle strips in guinea-pig stomach. To assess the role of $Ca^{2+}$ influx in underlying mechanism, slow waves were simultaneously recorded with spontaneous contractions using conventional intracellular microelectrode technique. At the concentration of $10^{-7}$ M, where NT showed maximum response, NT enhanced the magnitude $(863{\pm}198%,\;mean\;SEM,\;n=13)$ and the frequency $(154{\pm}10.3%,\;n=11)$ of spontaneous contractions. NT evoked a slight hyperpolarization of membrane potential, tall and steep slow waves with abortive spikes $(278{\pm}50%,\;n=4).$ These effects were not affected by atropine $(2\;{\mu}M),$ guanethidine $(2\;{\mu}M)$ and tetrodotoxin (0.2μM). NT-induced contractile responses were abolished in $Ca^{2+}-free$ solution and reduced greatly to near abolition by $10\;{\mu}M$ of verapamil or 0.2 mM of $CdCl_2.$ Verapamil attenuated the effects of NT on frequency and amplitude of the slow waves. Taken together, these results indicate that NT enhances contractility in guinea-pig gastric antral circular muscle and $Ca^{2+}$ influx through the voltage-operated $Ca^{2+}$ channel appears to play an important role in the NT-induced contractile mechanism.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 1992.04a
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• pp.30-35
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• 1992

Since many design problems in the railroad, aerospace and machine structures involve considerations of the effect of cyclic loading, manufacturing and quality control processes must fully account for fatigue of critical components. Due to the sensitivity of the Paris law, it is very important to calculate the ΔK numerically to minimize the error of predicted fatigue life in cycles. It is shown that the p-version of FEM based on LEFM analysis is far better suited for computing the stress intensity factors than the conventional h-version. To demonstrate the proficiency of the proposed scheme, the welded T-joint with crack problem of box car body bolster assembly and a crack problem emanating Iron a circular hole in finite strip have been solved.

• Bulletin of the Society of Naval Architects of Korea
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• v.20 no.2
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• pp.27-36
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• 1983

This paper presents numerical results of the added mass and damping coefficients of vertical axisymmetric bodies on or under the free surface. Also computed are the excitation forces on these bodies due to an incident regular wave system. The numerical scheme employs a localized finite-element method, which is based on the theory of the calculus of variations. The excitation forces and moments on a submerged half-spheroid lying on the bottom are computed and compared with the results obtained by others. he agreement is good. Several specific types of floating vertical axisymmetric platforms are considered for ten different wave lengths, in connection with the design of an ocean-thermal-energy converter platform. The added mass and damping coefficient, as well as the excitations, are presented. It is shown that simple strip theory gives a good approximation of the sway(and pitch) added mass for a disc platform having a long circular cylinder.

• Journal of the Korean Geotechnical Society
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• v.30 no.3
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• pp.29-46
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• 2014

For circular rigid footings with a rough base on sand, combined vertical - horizontal loading capacity was studied by three-dimensional numerical modelling. A numerical model was implemented to simulate the swipe loading and the probe loading methods and an interpretation procedure was devised in order to eliminate the numerical error from the restricted mesh density. Using the Mohr-Coulomb plasticity model, the effect of friction angle was studied under the associated flow-rule condition. The swipe loading method, which is efficient in that the interaction diagram can be drawn with smaller number of analyses, was confirmed to give similar results with the probe loading method, which follows closely the load-paths applied to real structures. For circular footings with a rough base, the interaction diagram for combined vertical (V) - horizontal (H) loading and the inclination factor were barely affected by the friction angle. It was found that the inclination factors for strip and rectangular footings are applicable to circular footings. For high H/V ratios, the results by numerical modelling of this study were smaller than the results of previous studies. Discussions are made on the factors affecting the numerical results and the areas for further researches.

• Journal of the Korea Computer Graphics Society
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• v.7 no.2
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• pp.29-35
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• 2001

In general, image-based virtual environment is represented by panoramic images created by image mosaic algorithm. The cylindrical panoramic image supports the fixed-viewpoint navigation due to the constraints of construction. Shum proposed concentric mosaics to allow users to navigate freely within a circular area[10]. It is constructed by a sequence of images which is acquired from a regularly rotating camera. Concentric mosaics technique, proposed by Shum, is considered as 3D plenoptic function which is defined three parameters : distance, height and angle. In this paper, we suggest an effective method for creating concentric mosaics, in which we first align a set of strip images on the cylinder plane and stitch the aligned strips to build a panoramic image. The proposed method has no constraints such as regular panning motion of camera. Furthermore, our proposed method minimizes the use of interpolation image to create a novel view images from the concentric mosaics. It allows the result image on a novel view to have better quality with respect to the number of input images.

• Journal of the Microelectronics and Packaging Society
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• v.20 no.4
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• pp.59-63
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• 2013

In this paper, the impact of the copper densities of substrate layers on IC package warpage is studied experimentally and numerically. The substrate strips used in this study contained two metal layers, with the metal densities and patterns of these two layers varied to determine their impacts. Eight legs of substrate strips were prepared. Leg 1 to leg 5 were prepared with a HD (high density) type of strip and leg 6 to leg 8 were prepared with UHD (ultra high density) type of strip. The top copper metal layer was designed to feature meshed patterns and the bottom copper layer was designed to feature circular patterns. In order to consider the process factors, the warpage of the substrate bottom was measured step by step with the following manufacturing process: (a) bare substrate, (b) die attach, (c) applying mold compound (d) and post reflow. Furthermore, after the post reflow step, the substrate strips were diced to obtain unit packages and the warpage of the unit packages was measured to check the warpage trends and differences. The experimental results showed that the warpage trend is related to the copper densities. In addition to the experiments, a Finite Element Modeling (FEM) was used to simulate the warpage. The nonlinear material properties of mold compound, die attach, solder mask, and substrate core were included in the simulation. Through experiment and simulation, some observations were concluded.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.21 no.5
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• pp.906-912
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• 2017

In this paper, we studied a design method for a broadband 3-element quasi-Yagi antenna (QYA) for indoor digital television (DTV) reception. The proposed QYA employs a novel balun between a microstrip (MS) line and a coplanar strip (CPS) line feeding the driver dipole. The proposed balun is constructed by connecting the end of MS line to CPS line through a shorting pin, and the CPS and ground reflector are connected through a circular ring-type conductor. An antenna, as an design example for the proposed antenna, is designed for the operation in the frequency band of 470-806 MHz for terrestrial DTV. The antenna fabricated on an FR4 substrate with a size of $270mm{\times}150mm$ showed a good performance such as a frequency band of 470-820 MHz for a voltage standing wave ratio < 2, a gain > 4.0 dBi, and a front-to-back ratio > 8.4 dB over the DTV frequency band.