The Korean Journal of Physiology
- Volume 25 Issue 2
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- Pages.147-158
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- 1991
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- 0300-4015(pISSN)
Excitatory Influences of Noradrenaline on the Spontaneous Contractions and Electrical Activity of Antral Circular Muscle of the Guinea-pig Stomach
- Lee, Taik-Jong (Department of Reconstructive and Plastic Surgery, Seoul National University College of Medicine) ;
- Kim, Jin-Hwan (Department of Reconstructive and Plastic Surgery, Seoul National University College of Medicine) ;
- Kim, Ki-Whan (Department of Physiology, Seoul National University College of Medicine)
- Published : 1991.12.01
Abstract
The effects of noradrenaline on the spontaneous contraction recorded from a strip of mucosa-free antral circular muscle were studied in the guinea-pig stomach, and the changes in slow waves and membrane resistance were analyzed in order to elucidate the mechanism for the excitatory response to noradrenaline. Electrical responses of circular muscle cells were recorded using glass microelectrodes filled with 3 M KCI. Electrotonic potentials were produced to estimate membrane resistance by the partition stimulating method. All experiments were performed in tris-buffered Tyrode solution which was aerated with 100%