• Title/Summary/Keyword: chronic administration

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Chronic Inflammatory Demyelinating Polyneuropathy Associated with HIV-Infection (사람면역결핍바이러스 감염과 연관된 만성염증탈수초다발신경병증)

  • Huh, So-Young;Ahn, Bo-Young;Oh, Se-Jin;Park, Yeong-Eun;Kim, Dae-Seong
    • Annals of Clinical Neurophysiology
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    • v.13 no.2
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    • pp.97-100
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    • 2011
  • Chronic inflammatory demyelinating polyneuropathy (CIDP) is an acquired immune-mediated polyneuropathy. Corticosteroids, intravenous immunoglobulin (IVIG) and plasmapheresis have been reported to be effective treatment. Rarely, CIDP can occur in the patients with HIV infection. The clinical features and electrophysiological findings of CIDP are known to be similar in patients with and without HIV infection. We report a 30-year-old male with HIV infection associated CIDP who improved after the administration of intravenous immunoglobulin and long term oral prednisone.

Implementation of a Weather Hazard Warning System at a Catchment Scale (시스템 구성요소 통합 및 현업서비스 구축)

  • Shin, Yong Soon
    • Proceedings of The Korean Society of Agricultural and Forest Meteorology Conference
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    • 2014.10a
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    • pp.74-85
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    • 2014
  • This study is a part of "Early Warning Service for Weather Risk Management in Climate-smart Agriculture", describes the delivery techniques from 840 catchment scale weather warning information using 150 counties unit special weather report(alarm, warning) released from KMA(Korea Meteorological Administration) and chronic weather warning information based on daily weather data from 76 synoptic stations. Catchment weather hazard warning service express a sequential risk index map generated by countries report occurs and report grade(alarm, warning) convert to catchment scale using zonal summarizing method. Additional services were chronic weather warning service at crop growth and accumulated more than 4 weeks, based on an unsuitable weather conditions, representing a relative risk compared to its catchment climatological normal conditions (normal distribution ) in addition to special weather report. Service provided by a real-time catchment scale map overlaid with VWORLD open platform operated by Ministry of Land, Infrastructure and Transport. Also provide a foundation for weather risk information to inform individual farmers to farm located within the catchment zone warning occur.

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The Study of Chronic Kidney Disease Classification using KHANES data (국민건강영양조사 자료를 이용한 만성신장질환 분류기법 연구)

  • Lee, Hong-Ki;Myoung, Sungmin
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2020.01a
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    • pp.271-272
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    • 2020
  • Data mining is known useful in medical area when no availability of evidence favoring a particular treatment option is found. Huge volume of structured/unstructured data is collected by the healthcare field in order to find unknown information or knowledge for effective diagnosis and clinical decision making. The data of 5,179 records considered for analysis has been collected from Korean National Health and Nutrition Examination Survey(KHANES) during 2-years. Data splitting, referred as the training and test sets, was applied to predict to fit the model. We analyzed to predict chronic kidney disease (CKD) using data mining method such as naive Bayes, logistic regression, CART and artificial neural network(ANN). This result present to select significant features and data mining techniques for the lifestyle factors related CKD.

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Intravenous Regional Administration of Prostaglandin E1 for the Treatment of Buerger's Disease (Buerger법 치료를 위한 국소 정맥내 Prostaglandin E1 주입)

  • Choe, Huhn;Kim, Dong-Chan;Han, Young-Jin
    • The Korean Journal of Pain
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    • v.5 no.1
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    • pp.85-88
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    • 1992
  • Buerger's disease is a chronic occlusive arterial disease in which a non-arteriosclerotic lesion involves medium-sized arteries, veins, and nerves of the distal leg or arm. Sympathetic interruption is indicated to improve blood flow to the involved extremity, although sympathetic blockade can provide temporally relief of vasospasm and pain. Chemical or surgical sympathectomy has been performed for this purpose and intravenous regional sympathetic block(IRSB) is an alternative. Guanethidine or reserpine has been administered for IRSB. Intraarterial or intravenous systemic administration of prostaglandin E1(PGE1) has been recommended for the treatment of Buerger's disease. We used PGE1 for intravenous regional administration as an IRSB with results as good as that of intraarterial injection. The advantages of the method include that it is less expensive than systemic administration, less invasive than intra-arterial injection, and simple in technical application.

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CLINICAL STUDY OF CHRONIC OSTEOMYELITIS (만성 골수염 환자의 임상적 연구)

  • Kim, Moon-Soo;Kim, Su-Gwan;Yeo, Hwan-Ho;Kim, So-Young;Kim, Soo-Min;Lee, Jun-Gil;Cho, Gyeong-An;Park, In-Soon
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.26 no.5
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    • pp.514-518
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    • 2000
  • Chronic osteomyelitis is often considered difficult to treat and may lead to refratory condition in oral and maxillofacial region. Clinical features of chronic osteomyelitis includes pain, swelling, pus discharge, and radiographic change. There are many kinds of treatment of chronic osteomyelitis. One of the most important factors in treating osteomyelitis are removal of infectious foci and administration of massive antibiotics. Recently we reviewed 29 patients with chronic osteomyelitis who visited in our department and treated successfully with our treatment protocols, consisting of surgical intervention and intravenous antibiotics for 2 weeks, and followed by oral antibiotics for 6 weeks. It is concluded that combination of surgical intervention and antibiotic therapy are sufficient to treat the chronic osteomyelitis in oral and maxillofacial region.

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Chronic Respiratory Symptoms and Associated Factors among Fruit and Vegetable Workers in Addis Ababa, Ethiopia: A Comparative Cross sectional Study

  • Mulualem Gete Feleke;Yidnekachew Alemu;Meaza Gezu Shentema;Samson Wakuma;Zerihun Emiru;Tesfaye Yitna Chichiabellu
    • Safety and Health at Work
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    • v.14 no.3
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    • pp.287-294
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    • 2023
  • Background: Fruit and vegetable market is an abundant source of bioaerosols. Exposure to organic and inorganic waste and long-term inhalation of bioaerosols during working hours leads to chronic respiratory symptoms. Hence, this study aimed to determine the prevalence of chronic respiratory symptoms and related factors among fruit and vegetable workers compared with the control group in Addis Ababa, Ethiopia. Methods and materials: A comparative cross-sectional study was conducted from 2020 to 2021. Data were entered in EpiData 3.1 and exported to Statistical Package for the Social Sciences (SPSS) version 25. Logistic regressions were computed to depict the data and related factors. The culture method was done to count and compare bacterial and fungal concentrations between fruit and vegetable workers and office workers. Results: In this study, the prevalence of chronic respiratory symptoms (PR = 2.87, 95% confidence interval [CI]: 1.772-4.66) was significantly higher among fruit and vegetable workers (46.7%) than controls (23.4%). Sex (adjusted odds ratio [AOR] = 2.11, 95% CI = 1.12-3.98), educational status (AOR = 1.34, 95% CI = 0.78-2.32), working hours per day (AOR = 3.91, 95% CI = 1.586-9.65), and working department (AOR = 3.20, 95% CI = 0.90-11.40) were associated with chronic respiratory symptoms. Bacterial and fungal concentrations were significantly higher in the air of the vegetable market (276 colony-forming unit) than the air in the workplace of controls (7 colony-forming unit). Conclusion: The fruit and vegetable market workers (greengrocers) had a higher prevalence of chronic respiratory symptoms relative to office workers. Respiratory protective devices should be given to deliver preventive measures.

An experimental study on the effects of Dokwhaljiwhang-tang affecting gastro-intestinal track and central nervous system in rats and mice (독활지황탕(獨活地黃湯)의 위장관(胃腸管) 및 중추신경(中樞神經)에 미치는 효능(效能)에 관(關)한 실험적(實驗的) 연구(硏究))

  • Jin, Hyon-Chol
    • Journal of Sasang Constitutional Medicine
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    • v.9 no.2
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    • pp.187-201
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    • 1997
  • An experimental study was done to examine the effects of Dokwhaljiwhang-tang on gastro-intestinal track and central nervous system and were undertaken by being carried out with rat. The following results have been obtained ; 1. Dokwhaljiwhang-tang showed to have an inhibitory effect on the smooth muscle contraction of the isolated ileum by acetylcholene chloride and barium chloride. 2. Dokwhaljiwhang-tang showed to have an inhibitory effect on the contraction of the gastric fundus-strip by acetylcholine chloride and barium chloride. 3. The preventive effect was recognized on the pylorus-ligated ulcer, by administration of Dokwhaljiwhang-tang. 4. The preventive effect was not recognized on the indomethacine -induced ulcer, by administration of Dokwhaljiwhang-tang. 5. The inhibitory effects on the secretion gastric juice, free acidity were recognized, by administration of Dokwhaljiwhang-tang 6. The transport ability in the small intestine was increased, by administration of Dokwhaljiwhang-tang. 7. The transport ability in the large intestine was increased, by administration of Dokwhaljiwhang-tang. 8. The analgesic effect was recognized, by administration of Dokwhaljiwhang-tang. 9. The effect of sleeping time was not recognized, by administration of Dokwhaljiwhang-tang. according to the results, it is considered that Dokwhaljiwhang-tang has effects of gastric ulcer, chronic gastritis,hyper-acidity, gastroptosis such as abdominal discomfort, gastric acid, indigestion and anorexia.

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Studies on variation of somatic cell in milk after administration of staphylococcus aureus vaccine and immunostimulant and antibiotics resistance of isolated staphylococcus spp in milk from dairy cow (유우에서 포도상구균 백신과 면역증강제 투여후 우유의 체세포수 변화 및 분리된 포도상구균의 항생제 내성에 관한 조사)

  • 성명숙;김규섭;김우현;박희주;배성수;권헌일
    • Korean Journal of Veterinary Service
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    • v.23 no.1
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    • pp.61-69
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    • 2000
  • Thirty-one dairy cow from two farm(more than 500,000 cells/ml of bulk milk) in Kyongbuk northern province were selected because of their high somatic cell(more than 500,000 cells/ml of milk In individual cow). Each cow received. staphylococcus aureus vaccine(Labac Staph) and immunostimulant(Ultracon) by intramuscular injection to be repeated every fifteen days for S times. The present study was investigated variation of somatic cell after administration of Labac Staph and Ultracon, and antibiotics resistance of isolated staphylococcus spp from milk in selected cow. The results obtained through the survey were summarized as follows ; 1. Ten dairy cow was injected in A farm. Chronic mastitic two cow after 2rd injection was weeded out the herd. Decrease rate of somatic cell after 1st, 2nd, ,3rd, 4th and 5th administration were 41.4%, 35.6%, 56.4%, 65.4% and 36.7%, respectively. Twenty-one cow was injected in B farm. Chronic mastitic five cow after ,3rd injection was weeded out the herd. Decrease rate of somatic cell after 1st, 2nd, 3rd, 4th and 5th administration were 36.9%, 59.9%, 24.5%, 62.6% and 78.4%, respectively. 2. In A farm, isolated staphylococcus spp were identified as S hyicus 2 strains(11.8%), coagulase negative staphylococcus 15 stains(89.2%) and S epidermidis 6strain(35.3%). In B farm, isolated staphylococcus spp were identified as S aureus 19 strains(55.98%) and coagulase negative staphylococcus 15 strains (44.2%). 3. In A fm, antibiotics resistant rate of isolated staphylococcus spp was high at ampicillin, penicillin and kanamycin, and middle at neomycin, streptomycin and erythromycin. in B farm, antibiotics resistant rate was moderate at ampicillin, penicillin, gentamicin, ka-namycin, neomycin, streptomycin, erythromycin and tetracycline, and coagulase negative staphylococcus spp was moderate at streptomycin.

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Effects of 8 weeks administration of Korean Panax ginseng extract on the mood and cognitive performance of healthy individuals

  • L., Reay J.;B., Scholey A.;O., Kennedy D.
    • Journal of Ginseng Research
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    • v.31 no.1
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    • pp.34-43
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    • 2007
  • Background: Previous research has suggested that single doses of a standardised Panax ginseng extract can decrease fasted blood-glucose levels and modulate cognitive performance in healthy young volunteers. The latter has generally been seen in terms of improved secondary memory performance. However, both the cognitive effects of chronic administration of ginseng and the potential modulation of working memory have received comparatively little research attention. Aims: The current double-blind, placebo-controlled, balanced cross-over study investigated the effects of 8-weeks administration of Korean ginseng extract (200 mg) on cognitive performance, gluco-regulatory parameters and ratings of subjective mood and 'quality of life'. Methods: 'Eighteen healthy young participants were assessed pre-dose and 3 hours post-dose on the mornings of Day 1, Day 29 and Day 57 of 8 week treatment regimens of both placebo and ginseng. A four-week placebo wash-out separated the treatment phases. Each assessment included the Cognitive Drug Research battery, computerised working memory tasks, and Bond-Lader mood scales. The WHO Quality of Life scale (WHOQOL-BREF) was completed once per visit. Gluco-regulatory parameters were assessed with assays of blood glucose, insulin and HbA1c. Results: Data from the 16 participants that completed the study showed that there were no significant, acute treatment related differences on Day 1 of treatment, or in gluco-regulatory parameters throughout the study. However, time related performance improvements were evident following chronic administration of ginseng on the '3-Back' and 'Corsi-block' computerised working memory tasks. Ginseng was also associated with an improved score on the 'social relations' subscale of the WHOQOL-100, and a significant shift on the 'calm' factor of the Bond-Lader mood scales (from calm/relaxed towards excited/tense). Conclusion: The results of the current study suggest that Korean ginseng extract can modulate working memory performance and subjective ratings of 'quality of life' and mood. Replication with a larger sample size may further elucidate the actions of this product.

Factors Related to the Outpatient Visits for Blood Pressure Management in Patients diagnosed with Hypertension (고혈압 진단자의 혈압 관리를 위한 외래 방문 영향요인)

  • Cho, Hyung-Kyung;Lee, Hyun-Ji;Seol, Jin-Ju;Lee, Kwang-Soo
    • Korea Journal of Hospital Management
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    • v.26 no.2
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    • pp.56-67
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    • 2021
  • Background: Regular doctor visits are vital for hypertension patients, especially for who have never received hypertension medication or non-pharmacologic therapy. This study purposed to study factors affecting outpatient visits for patients diagnosed with hypertension. Methods: This study included 59,009 respondents with hypertension over 30 from 2019 Community Health Survey data. Outpatient visits were defined by having hypertension treatments such as medication or non-pharmacologic therapy. Logistic regression was used to examine the factors affecting outpatient visits using SAS ver. 9.3. Results: 57,081(96.73%) patients with hypertension were identified as those having a outpatient visit for hypertension treatments, whereas 1,928(3.27%) patients did not have visits. Patient's characteristics such as gender, age, periods of hypertension, education level, perception of the blood pressure, hypertension management education, place of living, body mass index, depression and diabetes were found to have statistically significant relationship with the outpatient visits. Practical Implications: There is a need to select patients with high blood pressure who are unlikely to visit for hypertension treatments based on the study results. For those, establishing a personalized management plan such as health education and counseling programs will be helpful for the successful implementation of national chronic disease management program.