Chronic Inflammatory Demyelinating Polyneuropathy Associated with HIV-Infection

사람면역결핍바이러스 감염과 연관된 만성염증탈수초다발신경병증

  • Huh, So-Young (Department of Neurology, Pusan National University Yangsan Hospital) ;
  • Ahn, Bo-Young (Department of Neurology, Pusan National University Yangsan Hospital) ;
  • Oh, Se-Jin (Department of Neurology, Pusan National University Yangsan Hospital) ;
  • Park, Yeong-Eun (Department of Neurology, Pusan National University School of Medicine) ;
  • Kim, Dae-Seong (Department of Neurology, Pusan National University Yangsan Hospital)
  • 허소영 (양산부산대학교병원 신경과) ;
  • 안보영 (양산부산대학교병원 신경과) ;
  • 오세진 (양산부산대학교병원 신경과) ;
  • 박영은 (부산대학교 의학전문대학원 신경과학교실) ;
  • 김대성 (양산부산대학교병원 신경과)
  • Received : 2011.03.29
  • Accepted : 2011.06.22
  • Published : 2011.12.30

Abstract

Chronic inflammatory demyelinating polyneuropathy (CIDP) is an acquired immune-mediated polyneuropathy. Corticosteroids, intravenous immunoglobulin (IVIG) and plasmapheresis have been reported to be effective treatment. Rarely, CIDP can occur in the patients with HIV infection. The clinical features and electrophysiological findings of CIDP are known to be similar in patients with and without HIV infection. We report a 30-year-old male with HIV infection associated CIDP who improved after the administration of intravenous immunoglobulin and long term oral prednisone.

Keywords

References

  1. Snider WD, Simpson DM, Nielsen S, Gold JW, Metroka CE, Posner JB. Neurological complications of acquired immune deficiency syndrome: analysis of 50 patients. Ann Neurol 1983;14:403-418. https://doi.org/10.1002/ana.410140404
  2. Cornblath DR, McArthur JC, Kennedy PG, Witte AS, Griffin JW. Inflammatory demyelinating peripheral neuropathies associated with human T-cell lymphotropic virus type III infection. Ann Neurol 1987;21:32-40. https://doi.org/10.1002/ana.410210107
  3. Kim HJ, Kim S, Lee KB, Lee KW, Oh MD, Choe KW. Neurologic complications of human immunodeficiency virus-type 1 infection. J Korean Med Sci 2003;18:149-157.
  4. Robinson-Papp J, Simpson DM. Neuromuscular diseases associated with HIV-1 infection. Muscle Nerve 2009;40:1043-1053. https://doi.org/10.1002/mus.21465
  5. Verma A. Epidemiology and clinical features of HIV-1 associated neuropathies. J Peripher Nerv Syst 2001;6:8-13. https://doi.org/10.1046/j.1529-8027.2001.006001008.x
  6. Spudich SS, Nilsson AC, Lollo ND, Liegler TJ, Petropoulos CJ, Deeks SG, Paxinos EE, Price RW. Cerebrospinal fluid HIV infection and pleocytosis: relation to systemic infection and antiretroviral treatment. BMC Infect Dis 2005;5:98. https://doi.org/10.1186/1471-2334-5-98
  7. Petratos S, Gonzales ME. Can antiglycolipid antibodies present in HIV-infected individuals induce immune demyelination? Neuropathology 2000;20:257-272. https://doi.org/10.1046/j.1440-1789.2000.00356.x
  8. de la Monte SM, Gabuzda DH, Ho DD, Brown RH Jr, Hedley- Whyte ET, Schooley RT, Hirsch MS, Bhan AK. Peripheral neuropathy in the acquired immunodeficiency syndrome. Ann Neurol 1988;23:485-492. https://doi.org/10.1002/ana.410230510
  9. Fauci AS. The human immunodeficiency virus: infectivity and mechanisms of pathogenesis. Science 1988;239:617-622. https://doi.org/10.1126/science.3277274
  10. Panicker R, Bloom AL, Compston DA. Inflammatory demyelinating polyneuropathy in a haemophiliac associated with human immunodeficiency virus infection, responding to high dose intravenous immunoglobulin. Postgrad Med J 1988;64:699-700. https://doi.org/10.1136/pgmj.64.755.699