• Journal of Dental Anesthesia and Pain Medicine
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• 제19권6호
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• pp.323-341
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• 2019

Background: Local anesthetics alone or in combination with adjuncts, such as oral medications, have routinely been used for pain control during endodontic treatment. The best clinical choice amongst the vast numbers of agents and techniques available for pain control for irreversible pulpitis is unclear. This network meta-analysis combined the available evidence on agents and techniques for pulpal anesthesia in the maxilla and mandible, in order to identify the best amongst these approaches statistically, as a basis for future clinical trials. Methods: Randomized trials in MEDLINE, DARE, and COCHRANE databases were screened based on inclusion criteria and data were extracted. Heterogeneity was assessed and odds ratios were used to estimate effects. Inconsistencies between direct and indirect pooled estimates were evaluated by H-statistics. The Grading of Recommendation, Assessment, Development, and Evaluation working group approach was used to assess evidence quality. Results: Sixty-two studies (nine studies in the maxilla and 53 studies in the mandible) were included in the meta-analysis. Increased mandibular pulpal anesthesia success was observed on premedication with aceclofenac + paracetamol or supplemental 4% articaine buccal infiltration or ibuprofen+paracetamol premedication, all the above mentioned with 2% lignocaine inferior alveolar nerve block (IANB). No significant difference was noted for any of the agents investigated in terms of the success rate of maxillary pulpal anesthesia. Conclusion: Direct and indirect comparisons indicated that some combinations of IANB with premedication and/or supplemental infiltration had a greater chance of producing successful mandibular pulpal anesthesia. No ideal technique for maxillary anesthesia emerged. Randomized clinical trials with increased sample size may be needed to provide more conclusive data. Our findings suggest that further high-quality studies are required in order to provide definitive direction to clinicians regarding the best agents and techniques to use for mandibular and maxillary anesthesia for irreversible pulpitis.

• 한국의류산업학회지
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• 제15권1호
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• pp.138-146
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• 2013

Chemical compositions and biological functions of brown colorants extracted from pine bark(Pinus densiflora) have been studied. Dyeing test using multifiber fabrics with extracted colorants were preliminary carried out. Dyeing conditions and fastness tests of selected fabrics have been also studied. The brown colorants were produced 1.5% concentrations by solvent extraction from milled pine bark using methanol. The colorants were extracted with 80% methanol as best choice by a criteria of solid quantity and dyeability on fabrics. The chemical compositions were identified as mixtures of taxifolin epicatechin and procyanidin by LC/MS analysis. The brown colorants could be dyed not only natural fibers such as cotton, silk and wool but also synthetic fiber as nylon and semi-synthetic fiber as viscose rayon. Maximum K/S values was shown at 400 nm according to different fiber with color appearance of redish brown. Optimum pH and temperature of dyeing conditions was 4 and above $80^{\circ}C$, respectively. The brown colorants had a strong antioxidant activity compared to Butylated hydroxyanisole as standard and weak antimicrobial activity against E. coli. compared to kanamycin. Washing, rubbing, perspiration, dry cleaning and light fastness for cotton, nylon and silk dyed with the brown colorants were carried out by KS K method. Most of color fastness such as washing, rubbing, perspiration, and dry cleaning were represented as 4-5 grade. However, light fastness was reported as 2-3 grade. From this studies, brown colorants produced pine bark have a high potentials for natural dyeing on fabrics with antioxidant activity.

• 환경영향평가
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• 제23권6호
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• pp.517-526
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• 2014

본 연구는 객관적 방법으로써의 계층분석법(AHP)를 사용하여 최적의 철도사업의 노선선정에 있어서 필요한 환경 평가에 대한 중점항목의 가중치를 제시하여, 환경친화적인 노선 선택을 위한 정량적 기준을 제공하고자 하였다. AHP는 계층구조로 복합적인 선택 기준을 가진 각 기준들의 상대적 중요도를 평가하고, 대안들의 전체적인 우선 순위를 결정하는 의사결정의 접근법이다. 본 연구의 목적을 위해, 각 분야별 환경영향평가 검토를 담당하는 전문가 설문에 기초하여 철도사업 노선선정에 있어서 주요 환경평가 항목의 순위와 가중치를 정립하였다. 그 결과, AHP에 의한 가중치는 동 식물상, 지형 지질, 자연환경자산, 소음 진동, 수질, 위락 경관, 대기질 등 자연생태분야가 높게 나타났다. 보다 효율적인 환경친화적 노선 선정 체계를 개발하기 위해서는 환경적인 측면에 더불어, 기술적, 경제적, 사회적 측면도 고려되어야 할 것이다.

• 한국수학교육학회지시리즈E:수학교육논문집
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• 제29권3호
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• pp.313-330
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• 2015

분류 활동은 개념 형성과 직결되는 중요한 활동이다. 따라서 분류는 학습자 중심적인 교수를 통해 의미 충실한 학습이 이루어질 필요가 있다. 하지만 분류와 관련한 교수 학습이 '학습자 중심'이라는 구성주의 철학을 잘 반영하고 있을지 의구심이 제기된다. 이에 본 연구에서는 각과 삼각형의 분류와 관련한 초등 교과서 및 교사용지도서의 내용을 구성주의의 관점에서 비판적으로 분석해 보았다. 그 결과 각의 분류에서는 공동체의 합의에 의한 합리적 기준 설정의 기회가 제공되지 않는 문제점이 있었다. 삼각형의 분류는 다양성의 측면에서 다소 급진적인 형태를 띠고 있다는 문제점이 있었다. 또한 삼각형의 분류는 학생 반응 예측에서 이미 그 지식을 습득한 사람에게나 가능한 반응을 제안하는 경우를 접할 수 있었다. 그리고 계층적 분할적 분류에 대한 선택과 논의의 기회가 제공되지 않는 단점을 지니고 있었다. 이러한 특징을 바탕으로 '학습자 중심' 원칙의 충실한 반영, 학생 반응에 대한 신중한 예측, 결과보다 과정에 주목하는 교수를 지향할 것을 제안하였다.

• 대한수의학회지
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• 제43권3호
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• pp.471-476
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• 2003

Malignant catarrhal fever (MCF) is a systemic disease of ruminants caused by ovine herpesvirus 2 (OvHV-2). OvHV-2 is a gamma herpesvirus, which induces frequent latent infection and often difficult to detect its antigens and even specific nucleic acids because of its low viral copies in the infected tissues. Histopathology, serology and polymerase chain reaction (PCR) were compared for the diagnosis of MCF using 10 bison infected with OvHV-2. Histopathological diagnosis was performed using the criteria which was based upon the pathognomic lesions. Serological diagnosis was conducted using its serum with competitive ELISA for the detection of antibodies of OvHV-2. Also, the nest PCR was performed with peripheral blood leukocytes for the detection of OvHV-2-specific DNAs. Primers 556 and 775 were used for the primary amplification, and primers 556 and 555 were used for the secondary amplification. As the results, positive cases were 6 by histopahology, 9 by serology and 10 by PCR. As comparing with other diagnostic methods, PCR was found to be more sensitive than histopathology and serology. The recent development of molecular diagnostic assays has provided powerful tools for investigating how viruses survive in nature. Development of PCR specific for viruses has dramatically improved the accuracy of diagnosis of viruses in clinically infected animals. Furthermore, amplification of viral genomic material by nest PCR represents the most sensitive method for the detection of viruses and might be detected successfully even though very low viral DNA copies. So, it could be used as the first choice for the detection of viral DNAs with low copies such as the status of latent infection. However, it has also some limitation of application like as false negative results by PCR inhibitors and false positive results by contamination. The results of this study suggest that the use of molecular biological methods like PCR may increase the accuracy for the diagnosis of infectious diseases. However, in diagnostic laboratory, it is recommended that PCR assay must be conducted with other diagnostic methods for more reliable diagnosis.

• 대한교통학회지
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• 제28권3호
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• pp.75-84
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• 2010

현재 우리나라에서는 심각한 교통 혼잡문제와 도시 환경문제를 해결하고자 자전거 이용 활성화 정책을 추진하고 있다. 그러나 정부의 이러한 정책에도 불구하고, 자전거 이용자들은 여전히 자전거를 이용하는데 불편을 느끼고 있다. 따라서 본 연구에서는 이용자 중심의 자전거도로 서비스수준 모형을 개발하여 기존의 가전거도로 및 시설을 이용자 입장에서 평가하고 개선하는데 활용하고자 하였다. 본 연구에서는 실제 자전거 이용자들이 자전거도로를 이용하면서 느끼는 만족도로 자전거도로의 서비스수준을 정의하였다. 분석모형은 순차적 의미를 주는 선택, 선호와 관련된 분석에 적합한 순서형 프로빗 모형을 이용하였다. 또한, 자전거도로의 서비스수준은 실제 이용자들이 구별할 수 있는 수준인 3개(A~C) 범위로 정의하였다. 분석 결과, 이용자 중심의 자전거도로 서비스수준은 자전거도로 폭, 자전거도로축의 진 출입로 수, 자전거도로 유형, 보행자교통량, 대면횟수 순으로 정의되었다.

• 한국도서관정보학회지
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• 제42권4호
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• pp.31-50
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• 2011

교육에 있어서 평가는 피교육자의 성장과 발달 정도를 확인하고, 교육의 질적 향상을 도모하는 중요한 요소이다. 평가의 방법에는 여러 가지가 있으나 지필시험, 객관식 고사와 같은 전통적인 평가 방식이 갖는 한계를 극복하기 위해서 수행평가가 등장하였다. 수행평가는 피교육자가 과제를 완성한 정도나 상태를 바탕으로 평가하는 방법이다. 정보활용교육은 피교육자의 정보활용능력을 신장하는데 목적이 있으며, 수행평가는 정보활용능력의 상태나 정도를 측정하는데 매우 적합하다. 수행평가를 위해서는 먼저 수행과제가 준비되어 있어야 한다. 그러나 교수자가 수행평가의 요건을 모두 고려하여 수행과제를 개발한다는 것은 쉽지 않다. 이에 본 연구에서는 교수자가 정보활용교육을 전개함에 있어서 수행과제를 쉽게 제작할 수 있도록 수행과제 개발도구를 제안하고자 한다. 본 연구에서 제안한 수행과제 개발 도구는 템플릿 형태를 취하고 있으며, 4단계 즉, 교육목적 및 학습목표, 지식과 기능, 과제 유형, 측정 및 채점기준으로 구성하였다.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제21권2호
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• pp.101-110
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• 2018

Purpose: Functional constipation (FC) is a common gastrointestinal (GI) problem affecting children's well-being and quality of life. Although polyethylene glycol (PEG) is recommended as the first line therapy, it is not always applicable in lower socioeconomic populations. Hence, this study aimed to compare clinical courses of FC in children treated with different medications in order to identify prognostic factors related to treatment outcomes. Methods: We reviewed the medical records of patients aged ${\leq}15$ years diagnosed with FC according to the Rome IV criteria from 2007 to 2015 at the GI clinic, Songklanagarind Hospital. Baseline characteristic, medical history, and treatment outcomes were collected at first and subsequent visits. Results: Exactly104 patients (median age at diagnosis, 2.8 years) were diagnosed with FC. The number of follow-up visits per patient ranged from 1 to 35. The median duration of follow-up was 18.0 months (range, 6.0-84.2 months). PEG was given to 21% of patients. During the follow up period, 76% of patients experienced first recovery with a median time to recovery of 9.8 months. There were no significant differences in time until first recovery and relapse between patients who received and those who did not receive PEG (p=0.99 and 0.06, respectively). Age >6 years, normal defecation frequency, no history of cow's milk protein allergy, and use of laxatives were associated with successful outcomes. Conclusion: Treatment outcomes between patients who had and never had PEG demonstrated no significant difference in our study. Hence, current practices in laxative prescriptive patterns may be effective.

• 한국문헌정보학회지
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• 제50권4호
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• pp.55-75
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• 2016

본 논문은 임상의사가 선호하는 임상정보원의 특성과 정보검색 시 장애요인을 심층인터뷰를 통해 분석하였다. 환자 진료를 위한 정보검색은 환자치료방법 결정, 최신 경향 파악, 내부 컨퍼런스 발표자료 준비 등으로 구분되었으며, 이러한 검색행위에 영향을 미치는 변인으로는 주제 배경지식, 진료 경험, 직급, 검색 능력, DB 이용교육, 도서관 홈페이지 친숙도 등으로 나타났다. 온라인 임상정보원은 익숙하고 신뢰성이 높고 방대한 정보의 양 때문에 PubMed가 가장 선호되었으며, 속도가 빠르고 쓰기 쉬운 구글도 많이 사용되었다. 정보내용의 정확성과 최신성이 정보원 선정에 있어 가장 중요한 기준으로 적용되었으며, 시간이 많이 부족한 관계로 검색방법의 용이성, 정보에 대한 접근 편이성도 중요하게 여겨지고 있었다. 사용하기 불편한 검색시스템, 생소한 주제나 용어의 검색 어려움, 너무나 방대한 자료, 원문 접근의 어려움, 복잡한 고급검색 기능 등이 장애요인으로 도출되었다. 본 연구결과는 도서관 서비스 개선이나 임상의사의 정보검색 교육과정을 개선하는데 기초자료로 활용될 수 있을 것이다.

• Structural Engineering and Mechanics
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• 제74권4호
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• pp.567-576
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• 2020

Considerable controversy surrounds the choice of the best abutment type for implant prosthetics. The two most common structures are hex and non-hex abutments. The non-hex abutment typically furnishes a larger contact area between itself and the implant than that provided by a hex structure. However, when a hex abutment is loaded, the position of its contact area may be deeper than that of a non-hex abutment. Hence, the purpose of this study is to determine the different biomechanical behaviors of an internal bone-level implant based on the abutment type-hex or non-hex-and clinical crown length under static and cyclic loadings using finite element analysis (FEA). The hex structure was found to increase the implant and abutment stability more than the nonhex structure among several criteria. The use of the hex structure resulted in a smaller volume of bone tissues being at risk of hypertrophy and fatigue failure. It also reduced micromovement (separation) between the implant components, which is significantly related to the pumping effect and possible inflammation. Both static and fatigue analyses, used to examine short- and long-term stability, demonstrated the advantages of the hex abutment over the non-hex type for the stability of the implant components. Moreover, although its impact was not as significant as that of the abutment type, a large crown-implant ratio (CIR) increased bone strain and stress in the implant components, particularly under oblique loading.