• 제목/요약/키워드: channel 2

검색결과 8,673건 처리시간 0.034초

Identification of Three Types of Voltage Dependent $Ca^{2+}$-Channels in Mouse Follicular Oocytes

  • Bae, In-Ha;Yoon, Sook-Young;Yoon, Yong-Dal;Kim, Moon-Kyoo;Kim, Hae-Kwon
    • Animal cells and systems
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    • 제3권1호
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    • pp.53-58
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    • 1999
  • The immunocytochemical method was used to identify the existence of voltage-dependent $Ca^{2+}$-channels in mouse follicular oocytes. Three types of voltage-dependent $Ca^{2+}$-channels were shown to exist in the follicular oocytes for the first time, the P/Q-type $Ca^{2+}$-channel, the N-type $Ca^{2+}$-channel, and the L-type $Ca^{2+}$-channel. Among proven $Ca^{2+}$-channels distributions of the P/Q-type $Ca^{2+}$-channel and L-type $Ca^{2+}$-channel showed localized staining (clustered pattern) on the oolemma. The distribution of the P/Q-type $Ca^{2+}$-channel showed all localized staining, and the range of localized staining was from 1 to 8 in staining intensity. As the staining intensity increased from 1 to 8, the number of localized staining decreased. The L-type $Ca^{2+}$-channel are homogeneously stained (29.4%-54.2%), while some of them (around 28.7%-44.1%) showed localized staining on the oolemma. However, the rest of them showed no staining at all (17.1%- 26.5%). On the contrary, the N-type $Ca^{2+}$-channel showed mostly homogeneous staining, while nonstaining oocytes were around 33.8%. The rest showed localized staining (10%). However, staining intensity was much weaker than those of the P/Q-type and L-type $Ca^{2+}$-channel. In fact, the N-type $Ca^{2+}$-channel has been known to exist only in neurons (from ectoderm origin), but it is unknown how the N-type $Ca^{2+}$-channel exists in the follicular oocytes (from mesoderm origin). Further studies are needed to examine the expression of $Ca^{2+}$-channels during the developmental stages of the oocytes.

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Effects of $Cl^-$ Channel Blockers on the Cardiac ATP-sensitive $K^+$ Channel

  • Kwak, Yong-Geun
    • The Korean Journal of Physiology and Pharmacology
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    • 제3권3호
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    • pp.305-313
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    • 1999
  • To explore whether $Cl^-$ channel blockers interact with the ATP-sensitive $K^+\;(K_{ATP})$ channel, I have examined the effect of two common $Cl^-$ channel blockers on the $K_{ATP}$ channel activity in isolated rat ventricular myocytes using patch clamp techniques. In inside-out patches, 4,4'-diisothio-cyanatostilbene- 2,2'-disulfonic acid (DIDS) and niflumic acid applied to bath solution inhibited the $K_{ATP}$ channel activity in a concentration-dependent manner with $IC_{50}$ of 0.24 and 927 ${\mu}M,$ respectively. The inhibitory action of DIDS was irreversible whereas that of niflumic acid was reversible. Furthermore, DIDS-induced block was not recovered despite exposure to ATP (1 mM). In cell-attached and inside-out patches, DIDS blocked the pinacidil- or 2,4-dinitrophenol (DNP)-induced $K_{ATP}$ channel openings. In contrast, niflumic acid did not block the pinacidil-induced $K_{ATP}$ channel openings in inside-out patches, but inhibited it in cell-attached patches. DIDS and niflumic acid produced additional block in the presence of ATP and did not affect current-voltage relationship and channel kinetics. All these results indicate that DIDS among $Cl^-$ channel blockers specifically blocks the cardiac $K_{ATP}$ channel.

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페이딩 통신로의 통신 용량에 관한 연구 (A Study on the Channel Capacity of Fading Channel)

  • 고봉진;황인수;조성준
    • 한국통신학회논문지
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    • 제18권8호
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    • pp.1136-1145
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    • 1993
  • 여러가지 페이딩 통신로의 통신 용량을 구한 다음 이를 가우스 잡음 통신로의 통신 용량과 비교하여 각 페이딩 환경에 따른 통신 용량의 감소치를 구하였다. 그 결과 Rician페이딩 통신로에서는 직접파 대 반사파 전력비가, m-분포 페이딩 통신로에서는 지수 m이 커짐에 따라 페이딩 통신로의 통신용량은 가우스 잡음 통신로의 통신 용량에 가까워짐을 확인하였고 반송파 대 잡음 전력비(CNR)의 변화에 따른 가우스 잡음 통신로와 각 페이딩 통신로간의 통신 용량의 차이를 구해냈다. 또한 Rayleigh페이딩 통신로에 있어서2-branch 다이버시티의 도입으로 인한 통신 용량의 개선치를 구해냈다. 다이버시티로서는 검파전 최대비 합성법과 검파후 선택 합성법을 다루었다. 그 결과, 2-branch 사이의 상관계수 값에 관계없이 검파전 최대비 합성 다이버시티가 검파후 선택 합성 다이버시티보다 더 우수하였다. 상관계수 값의 변화에 따른 통신 용량의 개선치는 두 방식 모두 2-branch가 서로 무상관일때 가장 좋았으며, 2-branch사이의 상관계수 값이 작으면 작을수록 두 방식 모두 개선치가 커진다는 것을 알아냈다.

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Multichannel Quantum Defect Study of the Perturber's Effect on the Overlapping Resonances in Rydberg Series for the Systems Involving 2 Closed and Many Open Channels

  • Lee, Chun-Woo
    • Bulletin of the Korean Chemical Society
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    • 제31권6호
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    • pp.1669-1680
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    • 2010
  • The phase-shifted version of the multichannel quantum-defect theory (MQDT) was reformulated by disentangling the interloper spectrum from the perturbed dense Rydberg series for a systems involving 2 closed and more than 1 open channel. The theory was applied successfully to Martins and Zimmermann's photoionization spectra of the Rydberg series Cu I $3d^9\;4s(^1D_2)\;nd^2G_{9/2}$ perturbed by the interloper, $3d^9\;4p^2\;^4F_{9/2}$, for which Cohen's 4 channel QDT had failed. The zero surface graphic of the perturbed Fano's asymmetry parameter q of the autoionization spectrum of dense Rydberg series by the interloper was determined by only two parameters for this system. It was used as a map to trace the transformation route of the 3 channel autoionization spectra to the 4 channel spectra when the channel coupling of the closed channels with a newly added open channel was turned on progressively.

TELEMAC-2D모형을 이용한 개수로 분류흐름에 대한 수치모의 연구 (Numerical study of dividing open-channel flows at bifurcation channel using TELEMAC-2D)

  • 정대진;장창래;정관수
    • 한국수자원학회논문집
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    • 제49권7호
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    • pp.635-644
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    • 2016
  • 본 연구에서는 2차원 수치모형을 이용하여 개수로 분류부에서 분류수로 폭과 유량비 변화에 따른 흐름특성을 파악하였다. 2차류 영향을 고려한 분류부 수치모의시 흐름분포를 실험결과에 더 정확하고 안정하게 모의가능하다. 분류수로내 통수능을 감소시키는 흐름분리구역과 2차류의 상호 작용에 의한 흐름정체 효과는 분류유량비를 감소시킨다. 분류부 상류 유입유량과 유속이 감소할수록 수로폭 변화에 따른 분류유량비 변화가 더 크다. 동일 하류단 경계조건에서 분류수로 폭을 감소시킬 때, 본류 하류부 프루우드 수-분류유량비 관계식의 변화율은 -2.4843~-2.6675로 유사하게 나타난다. 동일 분류유량비 조건에서 분류수로 폭이 감소할수록 수축계수는 증가하고, 흐름분리구역의 폭은 감소한다. 분류수로 폭을 증가시킬 경우 분류부 상류 유입유량이 적을수록, 그리고 분류부 상류 유입량을 증가시킬 경우 분류수로 폭이 좁을수록 흐름분리구역 폭 감소율이 더 크다. 동일 상류 유입유량 조건에서 분류수로 폭이 감소할수록 분류유량비, 흐름분리구역의 길이와 폭은 감소한다.

Interference Coordination for Device-to-Device (D2D) under Multi-channel of Cellular Networks

  • Zulkifli, Aunee Azrina;Huynh, Thong;Kuroda, Kaori;Hasegawa, Mikio
    • Journal of Multimedia Information System
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    • 제3권4호
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    • pp.135-140
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    • 2016
  • To improve the throughput of Device-to-Device (D2D) communication, we focus on the scenario where D2D pair can reuse multi-channel of cellular communication. However, as sharing same channel with cellular communication can cause interference between D2D communication and cellular communication, a proper interference management is needed. In this paper, we propose interference-based channel allocation to select the channels to be used by D2D communication and a solution from game theory perspective to optimize the D2D communication throughput under multi-channel as well as guarantee the interference from it to cellular network. The simulation results verify the stability of the proposed method.

댐 하류 만곡부 하천에 대한 수리학적 특성 연구 (A Study on Hydraulic Characteristics of the Curved Channel in the Downstream of Dam)

  • 최한규;백효선;이계윤
    • 산업기술연구
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    • 제25권A호
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    • pp.3-14
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    • 2005
  • In order to accurately analyze the detailed hydraulic characteristics of the curved channel in the downstream of dam with the hydraulic structures such as bridge piers, RMA2 model which is one of two-dimensional models is applied to ChunCheon dam downstream curved channel. A series of hydraulic model tests are carried out for comparison studies. HEC-RAS model is also applied to the same site. There are no errors when velocities and water levels resulted from HEC-RAS model RMA2 model are compared with those of hydraulic model test on the straight channel. But, it is found that results of RMA2 model have a better agreement with those of hydraulic model test than those of HEC-RAS model on the curved channel with bridge piers. Additionally, RMA2 model can be predicted the eddy phenomena around bridge piers of the curved channel.

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Two-Bit/Cell NFGM Devices for High-Density NOR Flash Memory

  • Lee, Jong-Ho
    • JSTS:Journal of Semiconductor Technology and Science
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    • 제8권1호
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    • pp.11-20
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    • 2008
  • The structure of 2-bit/cell flash memory device was characterized for sub-50 nm non-volatile memory (NVM) technology. The memory cell has spacer-type storage nodes on both sidewalls in a recessed channel region, and is erased (or programmed) by using band-to-band tunneling hot-hole injection (or channel hot-electron injection). It was shown that counter channel doping near the bottom of the recessed channel is very important and can improve the $V_{th}$ margin for 2-bit/cell operation by ${\sim}2.5$ times. By controlling doping profiles of the channel doping and the counter channel doping in the recessed channel region, we could obtain the $V_{th}$ margin more than ${\sim}1.5V$. For a bit-programmed cell, reasonable bit-erasing characteristics were shown with the bias and stress pulse time condition for 2-bit/cell operation. The length effect of the spacer-type storage node is also characterized. Device which has the charge storage length of 40 nm shown better ${\Delta}V_{th}$ and $V_{th}$ margin for 2-bit/cell than those of the device with the length of 84 nm at a fixed recess depth of 100 nm. It was shown that peak of trapped charge density was observed near ${\sim}10nm$ below the source/drain junction.

전산유체역학을 이용한 Fischer-Tropsch 마이크로채널 반응기 반응채널구조에 따른 열적 효과 분석 (Analysis on Thermal Effects of Process Channel Geometry for Microchannel Fischer-Tropsch Reactor Using Computational Fluid Dynamics)

  • 이용규;정익환;나종걸;박성호;;한종훈
    • Korean Chemical Engineering Research
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    • 제53권6호
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    • pp.818-823
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    • 2015
  • 본 연구에서는 전산유체역학(CFD)을 이용하여 마이크로채널 내부의 Fischer-Tropsch(FT) 반응을 모사하였고, 나아가 반응채널의 너비와 높이, 냉각채널과의 거리 그리고 채널 사이 간격을 변수로 두고 채널 내부 온도에 대해 민감도 분석을 수행하였다. 마이크로채널 반응기는 채널 간의 열교환을 고려하기 위한 5개의 반응채널과 냉각채널을 대신한 냉각면으로 이루어져 있으며 채널의 높이와 너비를 포함한 변수들의 길이는 0.5 mm ~ 5.0 mm 범위에서 설정하였다. 반응물로는 $H_2$와 CO의 혼합기체($H_2/CO$ molar ratio=2)를 사용하였으며 반응기의 운전 조건은 $GHSV=10000h^{-1}$, 압력 20 bar와 온도 483 K($210^{\circ}C$)이다. 민감도 분석의 결과로 반응채널 내부의 최대 온도는 채널의 높이에 비례하며 너비에 대해서는 특정 길이 이상에서 영향을 받지 않는 것을 확인하였으며 이 중에 냉각채널과의 거리와 채널 사이 간격은 채널 내부 온도에 거의 영향을 미치지 않았다. 따라서 채널 레이아웃에서 반응채널의 높이는 짧을수록(약 2 mm 이하), 너비는 길수록(약 4 mm 이상) 열제거뿐만 아니라 생산량 측면에서 이득을 얻을 수 있었다.

Channel-fill Deposits of Gravel-bed Stream, Southeastern Eumsung Basin (Cretaceous), Korea

  • Ryang, Woo-Hun
    • 한국지구과학회지
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    • 제27권7호
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    • pp.757-767
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    • 2006
  • Alluvial-plain deposits in the southeastern part of the Eumsung Basin (Cretaceous) are characterized by coarse-grained channel fills encased in purple siltstone beds. It represents distinct channel geometry, infill organization, and variations in facies distribution. The directions of paleocurrent, sedimentary facies changes, and channel-fill geometry can be used to reconstruct a channel network in the alluvial system developed along the southeastern margin of the basin. The channel-fill facies represent downstream changes: 1) down-sizing and well-sorting in clast and martix of channel fills and 2) internal organization of scour fill or gravel lag and overlying cross-stratified, planar-stratified beds. These findings suggest multiple stages of channel-filling processes according to flooding and subsequent stream flows. In the small-scale pull-apart Eumsung Basin (${\sim}7{\times}33km^2$ in area), vertical-stacked alluvial architecture of the coarse-grained channel fills encased in purple siltstone is expected to result from episodic channel shifting under a rapidly subsiding setting.