• Title/Summary/Keyword: central composite design method

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Scale-up of Flat Panel Photobioreactor considering Hydrodynamics (수력학을 고려한 평판형 광생물 반응기의 스케일업에 관한 연구)

  • Kim, Gwang-Ho;Lee, Dong-Woon;Jeong, Sang-Hwa
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.17 no.1
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    • pp.48-56
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    • 2018
  • Due to the growing concerns of energy resource depletion and environmental destruction, the mass production of microalgae has been studied. The scale-up of a photobioreactor (PBR) is required for the mass production of biomass. In this paper, the geometric parameters and oxygen transfer rate (OTR) are considered, to scale up a flat panel photobioreactor (FP PBR). The PBR is designed using the goal-driven optimization (GDO) method to accomplish the scale-up. The local sensitivity of each output parameter with respect to the input parameter is analyzed through the design of experiment (DOE), and the design candidates are evaluated with the screening sampling method. The volumetric mass transfer coefficient is measured by the dynamic method.

Tolerance Optimization of Design Variables in Lower Arm by Using Response Surface Model and Process Capability Index (반응표면모델과 공정능력지수를 적용한 로워암 설계변수의 공차최적화)

  • Lee, Kwang Ki;Ro, Yun Cheol;Han, Seung Ho
    • Korean Journal of Computational Design and Engineering
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    • v.18 no.5
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    • pp.359-366
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    • 2013
  • In the lower arm design process, a tolerance optimization of the variance of design variables should be preceded before manufacturing process, since it is very cost-effective compared to a strict management of tolerance of products. In this study, a design of experiment (DOE) based on response surface model (RSM) was carried out to find optimized design variables of the lower arm, which can meet a given requirement of probability constraint for the process capability index (Cpk) of the weight and maximum stress. Then, the design space was explored by using the central composite design method, in which the 2nd order Taylor expansion was applied to predict a standard deviation of the responses. The optimal solutions satisfying the probability constraint of the Cpk were found by considering both of the mean value and the standard deviation of the design variables.

Determination of nickel and cadmium in fish, canned tuna, black tea, and human urine samples after extraction by a novel quinoline thioacetamide functionalized magnetite/graphene oxide nanocomposite

  • Naghibzadeh, Leila;Manoochehri, Mahboobeh
    • Carbon letters
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    • v.26
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    • pp.43-50
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    • 2018
  • In this research, a novel and efficient quinoline thioacetamide functionalized magnetic graphene oxide composite ($GO@Fe_3O_4@QTA$) was synthesized and utilized for dispersive magnetic solid phase preconcentration of Cd(II) and Ni(II) ions in urine and various food samples. A number of diverse methods were employed for characterization of the new nanosorbent. The design of experiments approach and response surface methodology were applied to monitor and find the parameters that affect the extraction performance. After sorption and elution steps, the concentrations of target analytes were measured by employing FAAS. The highest extraction performance was achieved under the following experimental conditions: pH, 5.8; sorption time, 6.0 min; $GO@Fe_3O_4@QTA$ amount, 17 mg; 2.4 mL $1.1mol\;L^{-l}$ $HNO_3$ solution as the eluent and elution time, 13.0 min. The detection limit is 0.02 and $0.2ng\;mL^{-1}$ for Cd(II), and Ni(II) ions, respectively. The accuracy of the new method was investigated by analyzing two certified reference materials (sea food mix, Seronorm LOT NO 2525 urine powder). The interfering study revealed that there are no interferences from commonly occurring ions on the extractability of target ions. Finally, the new method was satisfactorily employed for rapid extraction and determination of target ions in urine and various food samples.

Restoration after endodontic treatment with Endocrown (임상가를 위한 특집 3 - Endocrown을 이용한 근관치료 후 수복)

  • Park, Jeong-Kil
    • The Journal of the Korean dental association
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    • v.50 no.7
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    • pp.384-393
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    • 2012
  • Successful treatment of a badly broken down tooth with pulpal disease depends not only on good endodontic therapy, but also on good prosthetic reconstruction of the tooth after endodontic therapy is completed. The ideal treatment of endodontically treated teeth has been widely and controversially discussed. Endocrown is a restorative option for endodontically treated teeth. Endocrown design incorporates the core and short post into the crown as a single restoration. The preparation of endocrown consists of a circular equigingival butt-joint margin and central retention cavity of the entire pulp chamber instead of employing intraradicular posts. This design significantly increases the surface area of the preparation available for cementation. It is particularly useful in young patient teeth for long-term provisional restoration and in teeth with short clinical crowns. This technique represents a promising and conservative method for the treatment of endodontically treated teeth that require long-term protection and stability. Endocrown can be considered as a feasible alternative to full crowns or composite overlays for the restoration of non vital teeth.

Analysis of corrugated board panels under compression load

  • Biancolini, M.E.;Brutti, C.;Porziani, S.
    • Steel and Composite Structures
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    • v.9 no.1
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    • pp.1-17
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    • 2009
  • This paper is focused on the buckling and post buckling behaviour of rectangular corrugated board panels simply supported and subjected to compression load. The aim of the work is to understand the failure mechanism of investigated structure in order to quantify the effect of design parameters on the strength of a panel of given geometry. Two numerical models were developed adopting the finite element method. In the first one the corrugated board is represented by means of shell elements adopting an equivalent material, in the second the local structure is described in full detail modelling both straight and corrugated layers by means of shell elements and representing the connection between layers by special interface elements. The model correctness was checked by the comparison between out of plane central displacement predicted by the models and the experimental values found in literature. For the same case the effect of panel planarity error was evaluated. Finally a parametric analysis to investigate the effect of design parameters was carried out.

A trajectory prediction of human reach (Reach 동작예측 모델의 개발)

  • 최재호;정의승
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 1995.04a
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    • pp.787-796
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    • 1995
  • A man model is a useful design tool for the evaluation of man machine systems and products. An arm reach trajectory prediction for such a model will be specifically useful to present human activities and, consequently, could increase the accuracy and reality of the evaluation. In this study, a three-dimensional reach trajectory prediction model was developed using an inverse kinematics technique. The upper body was modeled as a four link open kinematic chain with seven degrees of freedom. The Resolved Motion Method used for the robot kinematics problem was used to predict the joint movements. The cost function of the perceived discomfort developed using the central composite design was also used as a performance function. This model predicts the posture by moving the joints to minimize the discomfort on the constraint of the end effector velocity directed to a target point. The results of the pairwise t-test showed that all the joint coordinates except the shoulder joint's showed statistically no differences at .alpha. = 0.01. The reach trajectory prediction model developed in this study was found to accurately simulate human arm reach trajectory and the model will help understand the human arm reach movement.

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Size Effect on the Modulus of Rupture in Automotive Ceramic Monolithic Substrate using Optimization and Response Surface Method (반응표면법과 최적화방법을 이용한 자동차 세라믹 모노리스 담체의 파단계수에 미치는 치수효과)

  • Baek, Seok-Heum;Shin, Soon-Gi;Joo, Won-Sik;Cho, Seok-Swoo
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.30 no.11 s.254
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    • pp.1392-1400
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    • 2006
  • Since the monolithic ceramic substrate was in introduced for automotive catalytic converters, the durability of the substrate has been a continuing requirement to reduce the emission, gas of vehicle. The substrate can occupy a volume as small as 82 $cm^3$ and as large as 8200 $cm^3$ to provide the required substrate for catalytic activity. The long-term durability varies with the size of the substrate from manufacture's point of view. Therefore this study presents that the response surface model using central composite design can explain size effect on the modulus of rupture in a cordierite ceramic monolithic substrate.

Assessment of Coal Combustion Safety of DTF using Response Surface Method (반응표면법을 이용한 DTF의 석탄 연소 안전성 평가)

  • Lee, Eui Ju
    • Journal of the Korean Society of Safety
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    • v.30 no.1
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    • pp.8-13
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    • 2015
  • The experimental design methodology was applied in the drop tube furnace (DTF) to predict the various combustion properties according to the operating conditions and to assess the coal plant safety. Response surface method (RSM) was introduced as a design of experiment, and the database for RSM was set with the numerical simulation of DTF. The dependent variables such as burnout ratios (BOR) of coal and $CO/CO_2$ ratios were mathematically described as a function of three independent variables (coal particle size, carrier gas flow rate, wall temperature) being modeled by the use of the central composite design (CCD), and evaluated using a second-order polynomial multiple regression model. The prediction of BOR showed a high coefficient of determination (R2) value, thus ensuring a satisfactory adjustment of the second-order polynomial multiple regression model with the simulation data. However, $CO/CO_2$ ratio had a big difference between calculated values and predicted values using conventional RSM, which might be mainly due to the dependent variable increses or decrease very steeply, and hence the second order polynomial cannot follow the rates. To relax the increasing rate of dependent variable, $CO/CO_2$ ratio was taken as common logarithms and worked again with RSM. The application of logarithms in the transformation of dependent variables showed that the accuracy was highly enhanced and predicted the simulation data well.

Optimal Parameter Design for a Cryogenic Submerged Arc Welding(SAW) Process by Utilizing Stepwise Experimental Design and Multi-dimensional Design Space Analysis (단계적 실험 설계와 다차원 디자인 스페이스 분석 기술을 통한 초저온 SAW 공정의 최적 용접 파라미터 설계)

  • Lee, Hyun Jeong;Kim, Young Cheon;Shin, Sangmun
    • Journal of Korean Society for Quality Management
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    • v.48 no.1
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    • pp.51-68
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    • 2020
  • Purpose: The primary objective of this research is to develop the optimal operating conditions as well as their associated design spaces for a Cryogenic Submerged Arc Welding(SAW) process by improving its quality and productivity simultaneously. Methods: In order to investigate functional relationships among quality characteristics and their associated control factors of an SAW process, a stepwise design of experiment(DoE) method is proposed in this paper. Based on the DoE results, not only a multi-dimensional design space but also a safe operating space and normal acceptable range(NAR) by integrating statistical confidence intervals were demonstrated. In addition, the optimal operating conditions within the proposed NAR can be obtained by a robust optimal design method. Results: This study provides a customized stepwise DoE method (i.e., a sequential set of DoE such as a factorial design and a central composite design) for Cryogenic SAW process and its statistical analysis results. DoE results can then provide both the main and interaction effects of input control factors and the functional relationships between the input factors and their associated output responses. Maximizing both the product quality with high impact strength and the productivity with minimum processing times simultaneously in a case study, we proposed a design space which can provide both acceptable productivity and quality levels and NARs of input control factors. In order to confirm the optimal factor settings and the proposed NARs, validation experiments were performed. Conclusion: This research may provide significant contributions and applications to many SAW problems by preparing a standardization of the functional relationship between the input factors and their associated output response. Moreover, the proposed design space based on DoE and NAR methods can simultaneously consider a number of quality characteristics including tradeoff between productivity and quality levels.

Machine learning modeling and DOE-assisted optimization in synthesis of nanosilica particles via Stöber method

  • Moradi, Hiresh;Atashi, Peyman;Amelirad, Omid;Yang, Jae-Kyu;Chang, Yoon-Young;Kamranifard, Telma
    • Advances in nano research
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    • v.12 no.4
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    • pp.387-403
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    • 2022
  • Silica nanoparticles, which have a broad range of sizes and specific surface features, have been used in many industrial applications. This study was conducted to synthesize monodispersed silica nanoparticles directly from tetraethyl orthosilicate (TEOS) with an alkaline catalyst (NH3) based on the sol-gel process and the Stöber method. A central composite design (CCD) is used to build a second-order (quadratic) model for the response variables without requiring a complete three-level factorial experiment. The process was then optimized to achieve the minimum particle size with the lowest concentration of TEOS. Dynamic light scattering and scanning electron microscopy were used to analyze the size, dispersity, and morphology of the synthesized nanoparticles. After optimization, a confirmation test was carried out to evaluate the confidence level of the software prediction. The results revealed that the predicted optimization is consistent with experimental procedures, and the model is significant at the 95% confidence level.