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Pemphigus-like Drug Reaction after Surgical Removal of a Splenic Hemangiosarcoma in a Dog

  • An, Sung-Ah;Wang, Hye-Bin;Han, Man-Gil;Jung, In-Sung;Song, Kun-Ho;Seo, Kyoung-Won
    • Journal of Veterinary Clinics
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    • v.34 no.2
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    • pp.103-107
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    • 2017
  • A 7-year-old spayed female Shih-tzu dog with 4-month history of anorexia and weight loss was diagnosed with splenic hemangiosarcoma. One week after splenectomy, the dog developed severe, multifocal, coalescing erosive and ulcerative dermatosis with epidermal collarettes and crusts on the dorsal trunk. The dog was prescribed systemic antibiotics comprising cephradine and enrofloxacin postoperatively. Histopathological examination of skin biopsies from haired skin lesions revealed changes consistent with pemphigus foliaceus (PF). Tentative diagnosis for this patient was pemphigus-like drug reaction resulting from cephradine treatment. However, given the dog's history of hemangiosarcoma, paraneoplastic pemphigus (PNP), a rarely reported cancer-related pemphigus in dogs, was also considered for tentative diagnosis. Significant clinical remission of dermal lesions was achieved with four weeks of prednisolone and mycophenolate mofetil (MMF) treatment. Drugs were gradually tapered and eventually discontinued with concurrent reduction of dermal lesions, and no further recurrence was noted.

Impact and Fatigue Analysis of Superposed Leaf Spring in Electric Power Switch (전력 개폐기의 중첩 판 스프링의 충격 피로 해석)

  • Park W.J.;Ahn K.Y.;Jeong K.Y.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.10a
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    • pp.794-797
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    • 2005
  • The automatic load transfer switch (ALTS), a kind of electric power switch, typically automatically transfers electrical loads from a normal electrical power source to an emergency electrical power source upon reduction or loss of normal power source voltage. It can also automatically re-transfer the load to the normal power source when the normal voltage has been restored within acceptable limits. The transfer operation of ALTS is accomplished by a spring-driven linkage mechanism. In order to control or delay the transfer switching time, the ALTS studied in this paper uses the superposed leaf springs, which are subjected to impact leadings in contacting with electrical contacts. Therefore, to confirm whether the springs has enough mechanical endurance in ALTS, we build a finite element model of the superposed lear springs using LS-DYNA and perform the impact and fatigue analysis.

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Utilizing Pedicled Muscle Flap for Defect Coverage after External Auditory Canal Cancer Resection (외이도에 발생한 악성종양에서 유경근육피판을 이용한 결손 재건)

  • Lee, Kangwoo Nathan;Kim, Eun Key
    • Archives of Craniofacial Surgery
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    • v.12 no.1
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    • pp.37-42
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    • 2011
  • Purpose: Cancer arising from the external auditory canal is a rare disease. A lesion that seems harmless in someway, can be lethal when inadequately excised, the tumor may infiltrate nerves, the parotid and auditory tissues before re-invading the skin. Wide resection of the lesion surrounding the structure and reconstruction with an adequate plan is crucial for the treatment of this disease. Methods: Two patients with external auditory canal cancer were treated with muscle flaps and skin grafts. Lateral temporal bone resection (LTBR) was performed for complete resection of the cancer. The defect cavity was obliterated with highly vascularized tissue using pedicled sternocleidomastoid muscle, and temporalis muscle individually, combined with full thickness skin graft for covering the skin defect of the ear. Results: Clear resection margin was obtained, and both patients showed disease free survival during the follow up. There was no complications of hematoma, infection, flap loss, or wound problem in both patients. Both patient received radiation therapy, there was no osteoradionecrosis or any other complication related to radiation therapy. Conclusion: Utilizing pedicled muscle flaps for managing defects after wide resection of the external auditory canal cancer is an effective method for managing this difficult disease.

Electrical Characteristics of Isotropic Conductive Adhesives (ICAs) for the Fabrication of RFID Inlays (RFID Inlay 제작용 등방성 도전 접착제의 전기적 특성 평가)

  • Lee, Jun-Sik;Kim, Jun-Ki;Kim, Mok-Soon;Lee, Jong-Hyun
    • Korean Journal of Metals and Materials
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    • v.47 no.7
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    • pp.447-453
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    • 2009
  • Isotropic conductive adhesives (ICAs) have been used or considered as an interconnect material for radio frequency identification (RFID) inlays or other flip chip assemblies due to the advantages of having a low temperature and high-speed bonding. In this work, the curing properties of commercial ICAs for the RFID tag application and the signal transmission in conductive lines that contained the ICA joints were evaluated as a function of the degree of cure at 900 MHz frequency range. The ICAs showed adequate signal transmission only after the curing process passed over the critical time. It was also found that the insertion loss of signal was more dependent on the contact states of Ag fillers in the bondline in preference to the electrical resistance of the ICA itself.

Characteristics of TiAlCrSiN coating to improve mold life for high temperature liquid molding (고온 액상 성형용 금형 수명 향상을 위한 TiAlCrSiN 코팅의 특성)

  • Yeo, Ki-Ho;Park, Eun-Soo;Lee, Han-Chan
    • Journal of Surface Science and Engineering
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    • v.54 no.5
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    • pp.285-293
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    • 2021
  • High-entropy TiAlCrSiN nano-composite coating was designed to improve mold life for high temperature liquid molding. Alloy design, powder fabrication and single alloying target fabrication for the high-entropy nano-composite coating were carried out. Using the single alloying target, an arc ion plating method was applied to prepare a TiAlCrSiN nano-composite coating had a 30 nm TiAlCrSiN layers are deposited layer by layer, and form about 4 ㎛-thickness of multi-layered coating. TiAlCrSiN nano-composite coating had a high hardness of about 39.9 GPa and a low coefficient of friction of less than about 0.47 in a dry environment. In addition, there was no change in the structure of the coating after the dissolution loss test in the molten metal at a temperature of about 1100 degrees.

Learning-Based Multiple Pooling Fusion in Multi-View Convolutional Neural Network for 3D Model Classification and Retrieval

  • Zeng, Hui;Wang, Qi;Li, Chen;Song, Wei
    • Journal of Information Processing Systems
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    • v.15 no.5
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    • pp.1179-1191
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    • 2019
  • We design an ingenious view-pooling method named learning-based multiple pooling fusion (LMPF), and apply it to multi-view convolutional neural network (MVCNN) for 3D model classification or retrieval. By this means, multi-view feature maps projected from a 3D model can be compiled as a simple and effective feature descriptor. The LMPF method fuses the max pooling method and the mean pooling method by learning a set of optimal weights. Compared with the hand-crafted approaches such as max pooling and mean pooling, the LMPF method can decrease the information loss effectively because of its "learning" ability. Experiments on ModelNet40 dataset and McGill dataset are presented and the results verify that LMPF can outperform those previous methods to a great extent.

Improvement of Thermoelectric Properties in Te-Doped Zintl Phase Magnesium-Antimonide

  • Rahman, Md. Mahmudur;Ur, Soon-Chul
    • Korean Journal of Materials Research
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    • v.31 no.8
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    • pp.445-449
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    • 2021
  • Zintl compound Mg3Sb2 is a promising candidate for efficient thermoelectric material due to its small band gap energy and characteristic electron-crystal phonon-glass behavior. Furthermore, this compound enables fine tuning of carrier concentration via chemical doping for optimizing thermoelectric performance. In this study, nominal compositions of Mg3.8Sb2-xTex (0 ≤ x ≤ 0.03) are synthesized through controlled melting and subsequent vacuum hot pressing method. X-ray diffraction (XRD) and scanning electron microscopy (SEM) are carried out to investigate phase development and surface morphology during the process. It should be noted that 16 at. % of excessive Mg must be added to the system to compensate for the loss of Mg during melting process. Herein, thermoelectric properties such as Seebeck coefficient, electrical conductivity, and thermal conductivity are evaluated from low to high temperature regimes. The results show that Te substitution at Sb sites effectively tunes the majority carriers from holes to electrons, resulting in a transition from p to n-type. At 873 K, a peak ZT value of 0.27 is found for the specimen Mg3.8Sb1.99Te0.01, indicating an improved ZT value over the intrinsic value.

The influence of the water ingression and melt eruption model on the MELCOR code prediction of molten corium-concrete interaction in the APR-1400 reactor cavity

  • Amidu, Muritala A.;Addad, Yacine
    • Nuclear Engineering and Technology
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    • v.54 no.4
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    • pp.1508-1515
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    • 2022
  • In the present study, the cavity module of the MELCOR code is used for the simulation of molten corium concrete interaction (MCCI) during the late phase of postulated large break loss of coolant (LB-LOCA) accident in the APR1400 reactor design. Using the molten corium composition data from previous MELCOR Simulation of APR1400 under LB-LOCA accident, the ex-vessel phases of the accident sequences with long-term MCCI are recalculated with stand-alone cavity package of the MELCOR code to investigate the impact of water ingression and melt eruption models which were hitherto absent in MELCOR code. Significant changes in the MCCI behaviors in terms of the heat transfer rates, amount of gases released, and maximum cavity ablation depths are observed and reported in this study. Most especially, the incorporation of these models in the new release of MELCOR code has led to the reduction of the maximum ablation depth in radial and axial directions by ~38% and ~32%, respectively. These impacts are substantial enough to change the conclusions earlier reached by researchers who had used the older versions of the MELCOR code for their studies. and it could also impact the estimated cost of the severe accident mitigation system in the APR1400 reactor.

Optimized Thermoelectric Properties in Zn-doped Zintl Phase Magnesium-Antimonide

  • Rahman, Md. Mahmudur;Ur, Soon-Chul
    • Korean Journal of Materials Research
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    • v.32 no.6
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    • pp.287-292
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    • 2022
  • Magnesium-antimonide is a well-known zintl phase thermoelectric material with low band gap energy, earth-abundance and characteristic electron-crystal phonon-glass properties. The nominal composition Mg3.8-xZnxSb2 (0.00 ≤ x ≤ 0.02) was synthesized by controlled melting and subsequent vacuum hot pressing method. To investigate phase development and surface morphology during the process, X-ray diffraction (XRD) and scanning electron microscopy (SEM) were carried out. It should be noted that an additional 16 at. % Mg must be added to the system to compensate for Mg loss during the melting process. This study evaluated the thermoelectric properties of the material in terms of Seebeck coefficient, electrical conductivity and thermal conductivity from the low to high temperature regime. The results demonstrated that substituting Zn at Mg sites increased electrical conductivity without significantly affecting the Seebeck coefficient. The maximal dimensionless figure of merit achieved was 0.30 for x = 0.01 at 855 K which is 30% greater than the intrinsic value. Electronic flow properties were also evaluated and discussed to explain the carrier transport mechanism involved in the thermoelectric properties of this alloy system.

Postoperative infection after cranioplasty in traumatic brain injury: a single center experience

  • Mahnjeong, Ha;Jung Hwan, Lee;Hyuk Jin, Choi;Byung Chul, Kim;Seunghan, Yu
    • Journal of Trauma and Injury
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    • v.35 no.4
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    • pp.255-260
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    • 2022
  • Purpose: To determine the incidence and risk factors of postoperative infection after cranioplasty in patients with traumatic brain injury (TBI). Methods: Data of 289 adult patients who underwent cranioplasty after TBI at a single regional trauma center between year 2018 and 2021 were reviewed retrospectively. Patient characteristics and various procedural variables, such as interval between craniectomy and cranioplasty, estimated blood loss, laterality and materials of the bone flap, and duration and classification of perioperative antibiotics usage were analyzed. Results: Postoperative infection occurred in 17 patients (5.9%). Onset time of infectious symptom ranged from 9 days to 174 days (median, 24 days) after cranioplasty. The most common cultured organism was Staphylococcus aureus (47.1%), followed by Klebsiella pneumoniae (17.6%) and Enterococcus faecalis (17.6%). Patients with postoperative infection were more likely to have diabetes (odds ratio [OR], 6.96; 95% confidence interval [CI], 1.92-25.21; P=0.003), lower body mass index (OR, 0.81; 95% CI, 0.66-0.98; P=0.029), and shorter duration of perioperative antibiotics (OR, 0.83; 95% CI, 0.71-0.98; P=0.026). Conclusions: For TBI patients with diabetes, poor nutritional status should be managed cautiously for increased risk of infection after cranioplasty. Further studies and discussions are needed to determine an appropriate antibiotics protocol in cranioplasty.