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Medullary Infarction Presenting as Sudden Cardiac Arrest: Report of Two Cases and Review of the Literature (급성 심정지로 나타난 연수경색)

  • Lee, Eung-joon;Choo, Il-yeon;Ha, Sue Young;Kwon, Hyung-min
    • Journal of the Korean neurological association
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    • v.36 no.4
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    • pp.310-313
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    • 2018
  • The causes of sudden death after medullary infarction involve arrhythmia, central respiratory failure, and dysautonomia. Sudden cardiac arrest in a medullary infarction is uncommon. Most of these cases experienced sudden cardiopulmonary arrest within 2 weeks from stroke onset as the extent of lesion increased. Here, we report two cases of medullary infarction presenting as sudden cardiac arrest. These cases indicate that medullary infarction could be one of the causes of sudden cardiac arrest.

Cloning and Expression of a Rice cDNA Encoding a Lls1 Homologue of Maize

  • Jwa, Nam-Soo;Park, Sang-Geun;Park, Chan-Ho;Kim, Soon-Ok;Ahn, Il-Pyung;Park, Sook-Young;Yoon, Choong-Hyo;Lee, Yong-Hwan
    • The Plant Pathology Journal
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    • v.16 no.3
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    • pp.151-155
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    • 2000
  • A cDNA (Oslls1) encoding Lls1-homologue of maize was isolated from cDNA library of rice (Oryza sativa cv. Ilpum). The 2,138 bp of full length Oslls1 clone contains an open reading frame of 1,623 nucleotides encoding 575 amino acid residues. The deduced amino acid sequence of Oslls1 has a high level of homology with chlorophyll a oxygenases of Arabidopsis thaliana (67%) and Marchantia polymorpha (65%). Southern blot analysis of genomic DNA indicates the existence of a small gene family for Oslls1 in the rice genome. The expression of Oslls1 mRNA was induced in leaves and germinating seeds. Treatment of $H_2O$$_2$significantly down-regulated Oslls1 expression. The expression of Oslls1 mRNA was consititutively down-regulated in the blm, a rice mutant exhibiting spontaneous necrotic lesions. These results suggest that this Oslls1 gene may be involved incell death mechanisms in the blm mutant of rice.

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Airway management of a patient incidentally diagnosed with Mounier-Kuhn syndrome during general anesthesia

  • No, Hyun-Joung;Lee, Jung-Man;Won, Dongwook;Kang, Pyoyoon;Choi, Seungeun
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.19 no.5
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    • pp.301-306
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    • 2019
  • Mounier-Kuhn syndrome (MKS) is a disease characterized by dilation of the trachea and mainstem bronchi. Due to the risk of airway leakage, pulmonary aspiration, and tracheal damage, MKS can be fatal in patients undergoing tracheal intubation. Moreover, MKS may not be diagnosed preoperatively due to its rarity. In this case, a patient undergoing neurosurgery was incidentally diagnosed with MKS during general anesthesia. During anesthesia induction, difficulties in airway management led the anesthesiologist to suspect MKS. Airway leakage was resolved in this case using oropharyngeal gauze packing. Anesthesiologists should be aware of the possibility of MKS and appropriate management of the airways.

Analytic Threshold Voltage Model of Recessed Channel MOSFETs

  • Kwon, Yong-Min;Kang, Yeon-Sung;Lee, Sang-Hoon;Park, Byung-Gook;Shin, Hyung-Cheol
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.10 no.1
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    • pp.61-65
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    • 2010
  • Threshold voltage is one of the most important factors in a device modeling. In this paper, analytical method to calculate threshold voltage for recessed channel (RC) MOSFETs is studied. If we know the fundamental parameter of device, such as radius, oxide thickness and doping concentration, threshold voltage can be obtained easily by using this model. The model predicts the threshold voltage which is the result of 2D numerical device simulation.

Non-osseous Coalition of the Third Metatarsal-Lateral Cuneiform Joint: A Case Report (제 3중족-외측 설상 관절에서 발생한 비골성 족근골 결합: 증례 보고)

  • Seo, Jae-Seong;Min, Hak-Jin;Kim, Ki Chun;Roh, Young Ju;Shin, Seong Kee
    • Journal of Korean Foot and Ankle Society
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    • v.22 no.4
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    • pp.177-180
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    • 2018
  • This paper reports a rare case of the symptomatic third metatarsal (MT3) - lateral cuneiform (LC) in a 55-year-old male who presented with complaints of severe intermittent pain in his right foot. Plain radiographs and computed tomography scans revealed sclerosis and irregularity at this joint. The intraoperative findings demonstrated a fibrocartilaginous coalition. The pain had improved one year after removing the MT3-LC joint by en bloc and arthrodesis.

Effect of Prophylactic Use of Silymarin on Anti-tuberculosis Drugs Induced Hepatotoxicity

  • Heo, Eunyoung;Kim, Deog Kyeom;Oh, So Hee;Lee, Jung-Kyu;Park, Ju-Hee;Chung, Hee Soon
    • Tuberculosis and Respiratory Diseases
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    • v.80 no.3
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    • pp.265-269
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    • 2017
  • Background: The first line of anti-tuberculosis (TB) drugs are the most effective standard of drugs for TB. However, the use of these drugs is associated with hepatotoxicity. Silymarin has protective effects against hepatotoxicity of anti-TB drugs in animal models. This study aims to investigate the protective effect of silymarin on hepatotoxicity caused by anti-TB drugs. Methods: This is a prospective, randomized, double-blind and placebo-controlled study. Patients were eligible if they were 20 years of age or order and started the first-line anti-tuberculosis drugs. Eligible patients were randomized for receiving silymarin or a placebo for the first 4 weeks. The primary outcome was the proportion of patients who showed elevated serum liver enzymes more than 3 times the upper normal limit (UNL) or total bilirubin (TBil) > $2{\times}UNL$ within the first 8 weeks of anti-TB treatment. Results: We enrolled a total of 121 patients who silymarin or a placebo to start their anti-TB treatment, for the first 8 weeks. The proportions of elevated serum liver enzymes more than 3 times of UNL at week 2, week 4, and week 8 did not show any significant difference between the silymarin and placebo groups, at 0% versus 3.6% (p>0.999); 4.4% versus 3.6% (p>0.999); and 8.7% versus 10.8% (p=0.630), respectively. However, patients with TBil >$2{\times}UNL$ at week 8 were significantly low in the silymarin group (0% versus 8.7%, p=0.043). Conclusion: Our findings did not show silymarin had any significant preventive effect on the hepatotoxicity of anti-TB drugs.