• Journal of the Korean Magnetic Resonance Society
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• v.21 no.2
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• pp.72-77
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• 2017

${\beta}-catenin$ is a key signaling protein which regulates cell signaling and gene transcription. Abnormal activation of ${\beta}-catenin$ is linked to many cancers, particularly with colorectal cancers. Although many genetic and biological studies on $Wnt/{\beta}-catenin$ have been reported and structures of the complex between ${\beta}-catenin$ and its diverse binding partners have been published, many of them have focused on armadillo repeat domain of ${\beta}-catenin$. Both N- and C-terminal domains have been suggested to regulate interactions of ${\beta}-catenin$ with other molecules, but still little is known about the C-terminal unstructured domain. To investigate the structure of this domain, construct of C-terminus was designed and structural studies were performed using size exclusion chromatography (SEC), circular dichroism (CD), fluorescence and nuclear magnetic resonance (NMR) spectroscopy. We observed that not only the purified full-length construct but the purified C-terminal construct also dimerizes in solution by SEC, suggesting that this domain involves in dimerization of ${\beta}-catenin$. CD and fluorescence data indicate its flexibility and structural formation in the presence of membrane environments.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.10
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• pp.6102-6113
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• 2014

This is an empirical study of the factors impacting on supervisee's satisfaction on coaching and supervision in Korea. The study set four independent variables (supervisor, supervisee, contents, and organization), a moderator variable (relationship between the supervisor and supervisee) and a dependent variable (supervision satisfaction) based on the theoretical background on supervision. The data was collected from a survey of 112 certified coaches who had experienced supervision. As a results of the hypotheses tests, the supervisor and organization factors affected the supervision satisfaction. The relationship between the supervisor and supervisee moderates the impact of the supervisor and supervisee on the supervision satisfaction. They reported that the effectiveness of the coaching supervision in Korea was strongly dependent on the supervisors. These results were attributed to the short history of the coaching supervision and the lack of experience related to it. They also suggested that a great deal of research on coaching supervision will be needed to develop a clear identity/framework of coaching supervisor and its methods.

• Korean Journal of Food Science and Technology
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• v.34 no.4
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• pp.610-616
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• 2002

In order to improve a complicated Cheongju manufacturing process, saccharification process with gelatinized rice flour was employed during a Cheongju fermentation. High sugar content without unsaccharified residue appeared to impede the yeast growth and fermentation. To solve this problem, addition of zeolite to the saccharifying solution containing 20% (w/v) sugar and fed-batch system were employed. These adjustments resulted in a increase of yeast viability and 40% time-saving alterations of fermentation. The Cheongju, having 18% (v/v) of ethanol content and fresh and rich flavor, could be made in 12 days. Yeast cells recovered from the fermentation precipitates could be reused up to four times without any adverse effect on cell viability, alcohol production, and flavor of the product. The complicated conventional brewing process of Cheongju can thus be simplified effectively.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.13 no.2
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• pp.172-181
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• 2006

Purpose: This study was done to identify observation and performance of nursing role activities by student nurses graduating from 3 year junior colleges or 4 year universities. Method: A descriptive design was used and the participants were 295 student nurses who were graduating. Data were collected using a structured questionnaire. Results: The average score for observation of nursing role activity was $2.16{\pm}0.29$, and for performance $1.61{\pm}0.29$. Among the college students, the mean item score for observation was highest for medication administrator and lowest for provider of spiritual & bereavement care, while for the university students the highest was for provider of care during surgery and lowest for provider of spiritual & bereavement care. The college students had higher scores for observation, and the university students for performance. Conclusion: It is concluded that standardized practice learning programs need to be designed in schools and in clinical practice areas, in order to further develop adaptability to nursing roles.

• Physical Therapy Rehabilitation Science
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• v.3 no.1
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• pp.38-42
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• 2014

Objective: In this study, we applied a neurodynamic sciatic nerve sliding technique to healthy adults to elucidate its effects on hamstring flexibility and postural balance. Design: Cross-sectional study. Methods: This study targeted twenty four healthy adults (16 men, 8 women). A neurodynamic sciatic nerve sliding technique was applied 5 times to all subjects' dominant leg. The subjects were asked to sit on the bed while performing cervical and thoracic flexion, as well as knee flexion with ankle plantar flexion. Then, they were asked to perform cervical and thoracic extension and knee extension with their ankle in dorsiflexion and maintain the position for 60 s. For postural balance, we measured postural sway while the subjects maintained a one-legged standing posture using the Good Balance System and measured the hip joint flexion range of motion using a standardized passive straight leg raise (SLR) test. Results: SLR test increased significantly from $79^{\circ}$ before the intervention to $91.67^{\circ}$ after the intervention (p<0.05). Regarding the participants' balance evaluated using the one-legged standing test, the X-speed decreased significantly from 18.61 mm/s to 17.17 mm/s (p<0.05), the Y-speed decreased from 22.28 mm/s to 20.52 mm/s (p<0.05), and the velocity moment was significantly decreased from $89.33mm^2/s$ to $74.99mm^2/s$ after the intervention (p<0.05). Conclusions: Application of the neurodynamic sciatic nerve sliding technique exhibited improved hamstring flexibility and postural balance of healthy adults.

• Journal of Korean Clinical Nursing Research
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• v.17 no.1
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• pp.57-69
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• 2011

Purpose: This study aimed to investigate the types of nursing organizational culture and its relationships with nurses' satisfaction with life, and job satisfaction. This study was eventually aimed to create healthier and more positive nursing organizational culture. Methods: This study utilized a descriptive correlational method to explore mediating effects of the types of nursing organizational culture on nurses' satisfaction with life and their job. Data were collected from a total of 1,801 nurses who have worked for more than 3 years in 35 different hospitals with more than 100 beds. Using SPSS 17.0 and Sobel Test Calculator, t-test, one way ANOVA, Duncan test, multiple regression and sobel test were used for data analysis. Results: The analysis showed that the nurses had a hierarchical organizational culture. Also the subjects' job satisfaction was significantly correlated with innovation, relation, and hierarchy-oriented factors and satisfaction with life. Conclusion: Innovative organizational culture is a leading factor in determining nurses' professional satisfaction. In view of the above it is recommended that strategies for creating innovative organizational culture and its application to nursing practice.

• Journal of Korean Clinical Nursing Research
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• v.17 no.3
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• pp.375-387
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• 2011

Purpose: Evidence-based practice (EBP) has emerged as a marker for healthcare quality and a global issue in nursing care. This study was conducted to identify Korean registered nurses' knowledge, attitudes, and practice about EBP in Korea. Methods: With a cross-sectional design, the EBP questionnaire (EBPQ) was administered to a convenience sample of nurses (N=453) recruited from 44 general hospitals. To increase the response rate, the directors of nursing were individually contacted by the researchers. The final response rate was 95.7%. Results: The majority of participants were females (99.3%), staff nurses (57.8%), and with bachelors degree (40.6%). Most of them (314, 73.4%) had ever heard about EBP. The overall mean score for the EBPQ was $4.72{\pm}0.69$ out of maximum score of 7. The mean score for the knowledge of EBP, attitudes towards EBP, and practice/use of EBP were $4.61{\pm}0.75$, $4.85{\pm}0.94$, and $4.90{\pm}0.88$, respectively. Educational level, age, and exposure to EBP were statistically significant predictors of Korean nurses' EBP perception. Conclusion: The findings showed that nurses with higher education are more likely to use and value the best available evidence for practice. This study suggests needs not only for further exploration but also for developing educational plans provided by each institute to assist nurses with the process of EBP and the associated skills.

• Journal of the Korean Society of Clothing and Textiles
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• v.45 no.4
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• pp.573-585
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• 2021

This paper describes the processes conducted in the analysis and conservation of suit worn by Yu Rim (1898-1961). The suit consists of a jacket and pants and is a typical Mao-style suit for independence activists; it is notable in that it was made of domestic wool. Inside the jacket, there is a machine embroidery of the name "Danju," a label of synthetic resin which reads "Daegu citizen's tailor's shop," and buttons engraved with "PUSAN SIN-HUNG." According to our textile analysis, the outer layer is composed of worsted wool while the lining is made from acetate. Damage to the garment from malodor and insects has been repaired, and the suit has been restored to its original shape by a conservation treatment that has reinforced the textiles. This conservation case can provide valuable research data on the preservation of modern and contemporary clothing. In addition, this study also attempts to estimate the date of suit worn by Yu Rim's production by comparing it with woolen suits produced around the same time and examining the clues associated with the relics. This is significant since it enhances the value of the cultural assets and provides detailed information on the historical transformation of domestic suits.

• Journal of Engineering Education Research
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• v.24 no.6
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• pp.3-19
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• 2021

This study aimed to introduce a case study of a basic engineering design course using the ENACT model for fostering social responsibility of engineers, and to investigate the educational effects of the course. Since the ENACT model was designed to encourage STEM college students to pursue responsible problem solving based on their understanding of socioscientific issues, we assumed that it would be beneficial for engineering students to foster their social responsibility as well as their understanding of science/engineering-related issues. A total of 49 engineering students who enrolled in the course participated in the study. Data included students' course artifacts, reflection papers, and responses to survey questionnaires. Results indicated that the students became more aware of nature of science and technology after the program, and began to solve the problems while considering the views of multiple stakeholders. They highly valued the experience of communicating with others as engaging in the civic activities. They also expressed high satisfaction and feeling of achievement on the course learning. We expect the ENACT model to be an effective teaching guideline that fosters the social responsibility of engineering students and furthermore, engineering ethics.

• International Area Studies Review
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• v.18 no.3
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• pp.3-21
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• 2014

The OECD DAC has recommended the member countries to raise the ODA budget by 0.7% of GNI. Most of DAC's members, howver, have not reached at the target level, mainly due to global economic crisis, with some exceptions in Northern Europe countries. Korea has increased the ODA budget allocation dramatically, but she could not still meet even the level 0.3%, which is the average level of DAC countries. In terms of national budget operation, DAC country groups are classified as the international norm type and the self-economic dependence type. And then, this study analyzes the time trends of the ODA budget in Korea, comparing with DAC's members on the economic scale. By forecasting Korean ODA budgets by country-type classifications, the optimal size of Korean government's ODA budget is proposed and discussed.