• Title/Summary/Keyword: cell compatibility

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Analysis for Compatibility of Gyejibongnyeong-hwan and Its Biological Activities (계지복령환(桂枝茯苓丸)의 배오(配伍)분석과 그 생리활성)

  • Kim, Do Hoy;Jung, Yang Sam;Yoon, Michung;Yoon, Yoosik;Shin, Soon Shik
    • Herbal Formula Science
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    • v.24 no.4
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    • pp.353-365
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    • 2016
  • Objectives : We analysed Gyejibongnyeong-hwan's compatibility principle and investigated biological activities by categorizing with molecular level, cellular level, animal level and human level based on Korean study for this formula. Methods : Gyejibongnyeong-hwan's compatibiltity principle was examined by the system of chief, deputy, assistant, and envoy. We looked into studies that presented in Korea from 1956 to 2016 about Gyejibongnyeong-hwan through Korea Institute of Oriental Medicine, Korean medicine information system (OASIS). Then classify into molecular level, cellular level, animal level and human level to analyse. Results : According to the system of chief, deputy, assistant, and envoy, chief herb is Cinnamomi Ramulus, deputy herb is Persicae Semen, assistant herb is Moutan Cortex, Paeoniae Radix, Poria, and envoy herb is Mel. Biological activities can be detected in transcription factors, enzymes, and inflammatory mediators for molecular level. For cellular level, it can be determined in human uterine endometrial cancer cell, human hepatocarcinoma cell, and human platelets. In mouse and rats for animal level, in overian cystoma, menorrhalgia, quality of life improvement in postmenopausal women, and blood stasis with motor vehicle accident for human level, biological activities was caught. Conclusions : From above results, Gyejibongnyeong-hwan is composed in line with the system of chief, deputy, assistan, and envoy. Biological activities are effective to improvement of menorrhalgia, anti-cancer, anti-oxidative, anti-inflammation, improvement of atherosclerosis, analgesic, anti-convulsion, wound healing, and improvement of liver function.

A Study on Electromagnetic Compatibility Performance Evaluation of Power Conditioning System for Residential Fuel Cell (가정용 연료전지 전력변환장치 전자파적합성 성능 평가 연구)

  • Choi, Young-Joo;Nam, Tae-Ho;Lee, Eun-Kyung;Lee, Duk-Gwon;Lee, Jung-Woon;Lee, Seung-Kuk;Moon, Jong-Sam
    • Journal of the Korean Institute of Gas
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    • v.21 no.6
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    • pp.23-29
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    • 2017
  • Solar and wind energy among the renewable energy produce irregular power because resource is difficult to control. When connected to grid have unstable. However, when the fuel cell system is connected to grid more stable because regular frequency and output power based on controllable hydrogen energy. To using fuel cell system in the household, it is important that the safety performance of power conditioning system(PCS) and it is important that evaluation method of electromagnetic compatibility(EMC). In this study, we consider that introduce power-frequency magnetic field immunity test before analyzed that compare with the EMC of the international standards and KGS AB 934 PC53. Also, we conduct that actual assessment and study on available the quantitative analysis as using complementary indicator.

Preparation of PHBV/Collagen Nanofibrous Mats and their Tissue Compatibility Compatibilscaffolds for tissue engineering

  • Meng, Wan;Kim, Se-Yong;Yuan, Jiang;Kim, Jung-Chul;Kwon, Oh-Hyeong;Ito, Yoshihiro;Kang, Inn-Kyu
    • Proceedings of the Polymer Society of Korea Conference
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    • 2006.10a
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    • pp.50-51
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    • 2006
  • The nanofibrous scaffolds were obtained by co-electrospinning PHBV and collagen Type I in HIFP. The resulting fiber diameters were in the range between 300 and 600 nm. The nanofiber surfaces were characterized by ATR-FTIR, ESCA and AFM. The PHBV and collagen components of the PHBV-Col nanofibrous scaffold were biodegraded by PHB depolymerase and a collagenase Type I aqueous solution, respectively. It was found, from the cell-culture experiment, that the PHBV-Col nanofibrous scaffold accelerated the adhesion of the NIH 3T3 cell compared to the PHBV nanofibrous scaffold, thus showing a good tissue engineering scaffold.

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리튬고분자 이차전지의 전기적 전기화학적 특성

  • 박수길;박종은;손원근;류부형;이주성
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 1998.06a
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    • pp.159-162
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    • 1998
  • The new type polymer electrolyte composed of polyacrylonitrile(PAN) baed polymer electrolyte contain LiClO$_4$-EC/PC and LiPF$\sub$6/-EC/PC were developed for the weightless and long or life time of lithium polymer battery system with using polyaniline electrode. The gel type electrolytes were prepared by PAN at different lithium salts in the glove box. We prepared for polymer electrolyte with knife casting method. The minimum thickness of PAN gel electrolyte for the slim type is about <400∼500$\mu\textrm{m}$. These gel electrolytes showed good compatibility with lithium electrode. The test cell of Li/polymer electrolyte/Lithium cobalt oxide solid state cell which was prepared by different lithium salt was researched by electrochemical technique. Resistance of polymer electrolyte which consist of LiClO$_4$ is more less than that of LiPF$\sub$6/ and cycle life is more longer than that of LiPF$\sub$6/.

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Electric and Electrochemical Characteristic of PMMA-PEO Gel Electrolyte for Rechargeable Lithium Battery

  • 박수길;박종은;이홍기;이주성
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.11 no.10
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    • pp.768-772
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    • 1998
  • The new type polymer electrolyte composed of polymethyl methacrylate(PMMA) - polyethy leneoxide(PEO) contain $LiClO_4$ -EC/PC was developed for the weightless and long or life time of lithium polymer batery system with using polyaniline electrode. the gel type electrolytes were prepared by PMMA with PEO at different lithium salts in the glove box. The minimum thickness of PMMA-PEO gel electrolyte for the slim type is about(400~450$\mu\textrm{m}$. These gel electrolyte showed good compatibility with lithium electrode. The test cell Li/polymer electrolyte/polyaniline solid state cell which was prepared by different lithium salt was researched by electrochemical technique.

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Characterization of PSCF3737 for intermediate temperature solid oxide fuel cell (IT-SOFC) (중.저온형 고체 산화물 연료전지의 공기극으로 사용되는 PSCF3737 물질의 특성에 관한 연구)

  • Park, Kwang-Jin;Bae, Joong-Myeon
    • 한국신재생에너지학회:학술대회논문집
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    • 2008.05a
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    • pp.61-64
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    • 2008
  • $Pr_{0.3}Sr_{0.7}Co_{0.3}Fe_{0.7}O_{3-\delta}$ (PSCF3737) was prepared and characterized as a cathode material for intermediate temperature-operating solid oxide fuel cell (IT-SOFC). X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), extended X-ray absorption fine structure (EXAFS), and electrical property measurement were carried out to study cathode performance of the material. XPS and EXAFS results proved that oxygen vacancy concentration was decreased and lattice constants of the perovskite structure material were increased by doping Fe up to 70 mol% at B-site of the crystal structure, which also extended the distance between oxygen and neighbor atoms. Thermal expansion coefficient (TEC) of PSCF3737 is smaller than that of $Pr_{0.3}Sr_{0.7}CoO_{3-\delta}$(PSC37) due to lower oxygen vacancy concentration. PSCF3737 showed better cathode performance than PSC37. It might be due good adhesion by a smaller difference of TEC between $Gd_{0.1}Ce_{0.9}O_2$ (CGO91) and electrode. Composite material PSCF3737-CGO91 showed better compatibility of TEC than PSCF3737. However, PSCF3737-CGO91 did not represent higher electrochemical property than PSCF3737 due to decreased reaction sites by CGO91.

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In vitro Cartilage Regeneration using Primary Chondrocytes Cultured within Porous Poly(lactide-co-glycolide) Scaffolds

  • Yun, Jun-Jin;Go, Ye-Jeong;Baek, Jeong-Hwan;Park, Tae-Gwan
    • 한국생물공학회:학술대회논문집
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    • 2000.11a
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    • pp.421-424
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    • 2000
  • Cartilage injuries are frequent nowadays. The previous surgical treatment of cartilage defect was limited. Another approach in the treatment of cartilage injuries is the use of reconstitute cartilage consisting of chondrocytes cultured in suitable biodegradable scaffolds. Current studies have demonstrated the compatibility of chondrocytes with different biomaterials and the chondrogenesis in various types of porous scaffolds. The cell ingrowth into the porous scaffolds is modulated by initial cell loading efficiency. Therefore, well-interconnected pore structure and even pore distribution of the scaffolds are essential for efficient cell seeding. According to our previous work, well-interconnected macroporous scaffolds can be prepared by gas-foaming/salt-leaching method using ammonium bicarbonate salt as porogen additives. In this work, primary chondrocytes were cultured in PLGA 65/35 scaffolds fabricated by using our method. Cells seeded in the scaffolds showed well distribution by agitated seeding method. Histochemical staining of proteoglycans present in the scaffolds was used to visualize the chondrocyte ingrowth in the scaffolds. At 3 weeks, the population of chondrocytes was increased for the most part of the scaffolds, and extra cellular matrix (ECM) secretion was increased as culture periods progressed.

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Effect of Poly(3-hydroxibutyrate-co-3-hydroxivalerate) Surface with Different Wettability on Fibroblast Behavior

  • Lee, Sang-Jin;Lee, Young-Moo;Khang, Gilson;Kim, Un-Young;Lee, Bong;Lee, Hai-Bang
    • Macromolecular Research
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    • v.10 no.3
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    • pp.150-157
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    • 2002
  • Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) is a microbial storage polymer with biodegradable properties. In order to improve the cell compatibility of PHBV surfaces, the physicochemical treatments have been demonstrated. In this study, physical method was corona discharge treatment and chemical method was chloric acid mixture solution treatment. The physicochemically treated PHBV film surfaces were characterized by the measurement of water contact angle, electron spectroscopy for chemical analysis, and scanning electron microscopy (SEM). The water contact angle of the physicochemically treated PHBV surfaces decreased from 75 to 30~40 degree, increased hydrophilicity. due to the introduction of oxygen-based functional group onto the PHBV backbone chain. The mouse NIH/3T3 fibroblasts cultured onto the physicochemically treated PHBV film surfaces with different wettability. The effect of the PHBV surface with different wettability was determined by SEM as counts of cell number and [$^3$H]thymidine incorporation as measures of cell proliferation. As the surface wettability increased, the number of the cell adhered and proliferated on the surface was increased. The result seems closely related with the serum protein adsorption on the physicochemically treated PHBV surface. In conclusion, this study demonstrated that the surface wettabilily of biodegradable polymer as the PHBV plays an important role for cell adhesion and proliferation behavior for biomedical application.

Solution-Processed Anti Reflective Transparent Conducting Electrode for Cu(In,Ga)Se2 Thin Film Solar Cells (CIGS 박막태양전지를 위한 반사방지특성을 가진 용액공정 투명전극)

  • Park, Sewoong;Park, Taejun;Lee, Sangyeob;Chung, Choong-Heui
    • Korean Journal of Materials Research
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    • v.30 no.3
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    • pp.131-135
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    • 2020
  • Silver nanowire (AgNW) networks have been adopted as a front electrode in Cu(In,Ga)Se2 (CIGS) thin film solar cells due to their low cost and compatibility with the solution process. When an AgNW network is applied to a CIGS thin film solar cell, reflection loss can increase because the CdS layer, with a relatively high refractive index (n ~ 2.5 at 550 nm), is exposed to air. To resolve the issue, we apply solution-processed ZnO nanorods to the AgNW network as an anti-reflective coating. To obtain high performance of the optical and electrical properties of the ZnO nanorod and AgNW network composite, we optimize the process parameters - the spin coating of AgNWs and the concentration of zinc nitrate and hexamethylene tetramine (HMT - to fabricate ZnO nanorods. We verify that 10 mM of zinc nitrate and HMT show the lowest reflectance and 10% cell efficiency increase when applied to CIGS thin film solar cells.

Effects and permeation property of anti-aging material from tinged autumnal leaves of Maple tree in the skin

  • Kim, Jin-Hwa;Lee, Jeong-Jae;Park, Sung min;Lee, Bum chun;Pyo, Hyeong-Bae
    • Proceedings of the SCSK Conference
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    • 2003.09b
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    • pp.464-478
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    • 2003
  • Free radicals and reactive oxygen species (ROS) caused by UV exposure or other environmental facts play critical roles in cellular damage and aging. The extract of tinged autumnal leaves of maple tree(Acer palmatum) has proven to be a powerful antioxidant. The Acer palmatum extract is very effective on the stabilization of biological membranes( containing unsaturated fatty acid). We studied photoprotective effect of the extract against UVB-induced cytotoxicity in human keratinocytes. The extract improved cell viability comparing to control after UVB irradiation. In the determination test of pro inflammatory cytokines the extract decreased expression of interleukin 1 a and 6, which play an important role in inflammation and skin erythema caused by UV. We also studied property of varying cosmetic formulations on the percutaneous absorption of the extract. After 24 hour in vitro penetration study, the content of the extract was more highly detected in skin residue part. This result showed the extract had relatively high compatibility of skin in our emulsion system. On human skin, after appling the product containing the extract we obtained a good result of antiwrinkle effect by skin visiometer. In conclusion, the Acer palmatum extract is a photoprotective and very effective in stressed and aged skin care. And we can predict the extract mainly affects on the skin cell and tissue in our emulsion system.

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