• 한국표면공학회:학술대회논문집
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• 한국표면공학회 2018년도 춘계학술대회 논문집
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• pp.140-140
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• 2018

The 3D interconnect technologies have been appeared, as the density of Integrated Circuit (IC) devices increases. Through Silicon Via (TSV) process is an important technology in the 3D interconnect technologies. And the process is used to form a vertically electrical connection through silicon dies. This TSV process has some advantages that short length of interconnection, high interconnection density, low electrical resistance, and low power consumption. Because of these advantages, TSVs could improve the device performance higher. The fabrication process of TSV has several steps such as TSV etching, insulator deposition, seed layer deposition, metallization, planarization, and assembly. Among them, TSV metallization (i.e. TSV filling) was core process in the fabrication process of TSV because TSV metallization determines the performance and reliability of the TSV interconnect. TSVs were commonly filled with metals by using the simple electrochemical deposition method. However, since the aspect ratio of TSVs was become a higher, it was easy to occur voids and copper filling of TSVs became more difficult. Using some additives like an accelerator, suppressor and leveler for the void-free filling of TSVs, deposition rate of bottom could be fast whereas deposition of side walls could be inhibited. The suppressor was adsorbed surface of via easily because of its higher molecular weight than the accelerator. However, for high aspect ratio TSV fillers, the growth of the top of via can be accelerated because the suppressor is replaced by an accelerator. The substitution of the accelerator and the suppressor caused the side wall growth and defect generation. The suppressor was used as Single additive electrodeposition of TSV to overcome the constraints. At the electrochemical deposition of high aspect ratio of TSVs, the suppressor as single additive could effectively suppress the growth of the top surface and the void-free bottom-up filling became possible. Generally, copper was used to fill TSVs since its low resistivity could reduce the RC delay of the interconnection. However, because of the large Coefficients of Thermal Expansion (CTE) mismatch between silicon and copper, stress was induced to the silicon around the TSVs at the annealing process. The Keep Out Zone (KOZ), the stressed area in the silicon, could affect carrier mobility and could cause degradation of the device performance. Cobalt can be used as an alternative material because the CTE of cobalt was lower than that of copper. Therefore, using cobalt could reduce KOZ and improve device performance. In this study, high-aspect ratio TSVs were filled with cobalt using the electrochemical deposition. And the filling performance was enhanced by using the suppressor as single additive. Electrochemical analysis explains the effect of suppressor in the cobalt filling bath and the effect of filling behavior at condition such as current type was investigated.

• Asian Spine Journal
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• 제12권6호
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• pp.1060-1068
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• 2018

Study Design: Retrospective study. Purpose: Lumbar intervertebral disc degeneration is an important cause of low back pain. Overview of Literature: Spinal fusion is often reported to have a good course for adolescent idiopathic scoliosis (AIS). However, many studies have reported that adjacent segment degeneration is accelerated after lumbar spinal fusion. Radiography is a simple method used to evaluate the orientation of the vertebral column. magnetic resonance imaging (MRI) is the method most often used to specifically evaluate intervertebral disc degeneration. The Pfirrmann classification is a well-known method used to evaluate degenerative lumbar disease. After spinal fusion, an increase in stress, excess mobility, increased intra-disc pressure, and posterior displacement of the axis of motion have been observed in the adjacent segments. Methods: we retrospectively secured and analyzed the data of 15 patients (four boys and 11 girls) with AIS who underwent a spinal fusion surgery. We studied the full-length view of the spine (anterior-posterior and lateral) from the X-ray and MRI obtained from all patients before surgery. Postoperatively, another full-length spine X-ray and lumbosacral MRI were obtained from all participants. Then, pelvic tilt, sacral slope, curve correction, and fused and free segments before and after surgery were calculated based on X-ray studies. MRI images were used to estimate the degree to which intervertebral discs were degenerated using Pfirrmann grading system. Pfirrmann grade before and after surgery were compared with Wilcoxon signed rank test. While analyzing the contribution of potential risk factors for the post-spinal fusion Pfirrmann grade of disc degeneration, we used generalized linear models with robust standard error estimates to account for intraclass correlation that may have been present between discs of the same patient. Results: The mean age of the participant was 14 years, and the mean curvature before and after surgery were 67.8 and 23.8, respectively (p<0.05). During the median follow-up of 5 years, the mean degree of the disc degeneration significantly increased in all patients after surgery (p<0.05) with a Pfirrmann grade of 1 and 2.8 in the L2-L3 before and after surgery, respectively. The corresponding figures at L3-L4, L4-L5, and L5-S1 levels were 1.28 and 2.43, 1.07 and 2.35, and 1 and 2.33, respectively. The lower was the number of free discs below the fusion level, the higher was the Pfirrmann grade of degeneration (p<0.001). Conversely, the higher was the number of the discs fused together, the higher was the Pfirrmann grade. Conclusions: we observed that the disc degeneration aggravated after spinal fusion for scoliosis. While the degree of degeneration as measured by Pfirrmann grade was directly correlated by the number of fused segments, it was negatively correlated with the number of discs that remained free below the lowermost level of the fusion.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제30권5호
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• pp.414-421
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• 2004

This is a reprospective study on the care of odontogenic infections in admission patients with geriatric diseases. The study was based on a series of 480 patients at Dong San Medical Center, Wonju Christian Hospital and Il San Health Insurance Hospital, From Jan. 1, 2000, to Dec. 31, 2002. The Obtained results were as follows: 1. The systemic malignant tumor was the most frequent cause of the geriatric diseases with odontogenic infectious diseases, and refractory lung disease, systemic heart disease, type II diabetes mellitus, cerebrovascular disease, bone & joint disease, senile psychologic disease were next in order of frequency. 2. Male prediction(57.5%) was existed in the odontogenic infectious patients with geriatric diseases. But, there were female prediction in senile psychologic disease, systemic heart disease and cerebrovascular disease. 3. The most common age group of the odontogenic infectious patient with geriatric disease was the sixty decade(47.9%), followed by the seventy & eighty decade in order. 4. In the contents of chief complaints on the odontogenic infectious patients with geriatric disease, peak incidence was occurred as toothache(52.7%), followed by extraction wish, tooth mobility, oral bleeding, oral ulcer, fracture of restoration, gingival swelling in order. 5. In the diagnosis group of odontogenic infectious diseases, periodontitis, pulpitis & periapical abscess were more common. 6. In the treatment group of odontogenic infectious diseases, the most frequent incidence(34.2%) was showed in primary endodontic treatment (pulp extirpation, occlusal reduction and canal opening drainage) and followed by scaling, incision & drainage, only drugs, pulp capping, restoration in order.

• Clinical and Experimental Pediatrics
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• 제52권9호
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• pp.1005-1014
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• 2009

목 적:간질아동의 치료과정에서 이들을 돌보는 부모들은 스트레스, 사회적 낙인 등으로 인한 정신사회적 곤란으로 삶의 질이 저하될 수 있다. 따라서 본 연구는 간질아동 부모들의 간질에 대한 지각된 낙인과 삶의 질을 평가하고 지각된 낙인이 간질아동의 질병관련 변수들과 삶의 질 사이에서 매개변수로 작용하는지 조사하고자 하였다. 방 법:경기, 부산, 대구, 경북 소재 5개 대학병원의 소아간질클리닉에서 간질로 진단받고 치료중인 간질아동의 부모 260명을 대상으로 지각된 낙인과 삶의 질 측정도구 등 구조화된 설문조사를 실시한 후 통계학적으로 분석하였다. 결 과:부모들의 삶의 질 수준은 비교적 양호하게 나타났으며 지각된 낙인이 간질아동의 질병관련 변수들과 삶의 질 사이에서 매개변수로 작용함을 확인하였다. 지각된 낙인, 고용 여부, 월수입, 종교 유무, 여가시간은 간질아동 부모의 삶의 질에 직접적으로 영향을 미치는 것으로 나타났고, 간질아동의 질병관련 변수들인 동반장애 유무 및 경련의 빈도는 매개변수인 지각된 낙인을 통해 간접효과를 미치는 것으로 나타났다. 총인과 효과는 동반장애 유무, 지각된 낙인, 고용여부, 월수입 순으로 크게 나타나 지각된 낙인의 매개효과가 매우 중요함을 알 수 있었다. 결 론:간질아동 부모들의 삶의 질이 다양한 사회경제적 요인 및 아동의 의학적 요인에 의해 영향 받으며 간질에 대한 지각된 낙인의 역할이 중요함을 알 수 있었고, 그들의 삶의 질 향상을 위해서는 다학문간의 공동 노력이 필요할 것으로 보인다.

• Asian-Australasian Journal of Animal Sciences
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• 제21권6호
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• pp.861-867
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• 2008

The objective of this study was to evaluate the effect of exogenous ghrelin on the behaviors, weight gain, and feed intakes of weanling piglets. A total of 25 pairs of Duroc$\times$Landrace$\times$Large White piglets weaned at 21 days of age were used in this experiment which finished on day 36. Each pair of healthy piglets from the same litter with similar body weight and of the same gender were selected and randomly arranged to ghrelin or control groups. Thus, there were 50 piglets (ghrelin 25; control 25) kept in 10 pens (ghrelin 5; control 5) and 5 piglets per pen. Initial body weight of the pigs did not differ between the control and ghrelin treatment ($7.43{\pm}0.17kg$; p = 0.81). Experimental pigs were infused with ghrelin ($1{\mu}g/d$ pig) via the marginal ear vein between 0750 and 0800 h at 22, 23, 24 days of age. Control pigs were infused with 0.9% saline. Feed consumption was measured on days 23, 24, 25, 29 and 36. Body weight was measured on days 22, 23, 24, 25, 29 and 36. Behavior data of individual piglets were collected by real-time observation from 0800-1500 h through remote supervisory equipment at 22, 23 and 24 days of age. The results indicated that ghrelin infusion could increase drinking (p<0.05) and lying behaviors (p<0.01) and decrease mounting behaviors (p<0.05). No significant influence of ghrelin was found on average daily weight gain (ADG) and average daily feed intake (ADFI) in this experiment (p>0.05). In conclusion, exogenous ghrelin by the method above and at the dosage of $1{\mu}g/d$ pig could cause a variety of behavioral effects, but not improve performance of weanling piglets.

• 보건교육건강증진학회지
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• 제9권1호
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• pp.39-47
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• 1992

This study was surveyed among 1136 respondent of high school girls in seoul from Feb. 6, till Feb. 22, 1992 for the purpose of analysing the smoking of high school girls and its factor. The data was analied by X²-test and Multiple Regression and shows the following. 1. Out of 1,136 respondent, the current smokers were found to be 176, 15.5% and the former smokers were 204, 18.0%. This implies that 23.5% of high school girls seoul have experience smoking. 2. For the first smoking time in both smoking group and former smokers, it shows that the third grade of middle school lead the lists. 36.9% (65) of the smokers and 37.3(75)of former smokers experienced the first smoking at that time. 70.5%(124) of the smoking group have the intention to stop smoking and the first reason of it is health problem, 65.6%(75). 3. For the type of the school the smoking rate rages from 2.7%(7) of literary part in day time to 25.3%(97) of vocational part in evening time and the rate of smoking experience shows from 9.9%(26) literary part in day time to 25.3%(97) of vocational part in evening time. This data show that literary part in day time has the lowst rate while vocational part in eveing time the highest rate. 4. Compared with non smoker group, smoking group and former smoking group spent more money (P<0.001) and felt dissatisfied with school life and didn't have good school records. 5. Smoking group and former smokers have more boy friends than non smoking group and in most cases their boy friend have smoking habits (P<0.001) and it is the same with their gril friend (P<0.001). 6. Compared with non smoker group, smoking group and former smokers lack of their parents' interest (P<0.001). But whether it is strict or free there is little difference among the three group. 7. For smoking group and former smoking group, in most cases their parent, brother and sister tend to smoke and especially their sisters' smoking has much influence on their smoking in comparison with non-smokers. 8. Compared with non-smoker group, smoking group and former smoking group tend to think less of the harm of smoking. In regard with health problem, more smoking group and former smokers think that smoking can relieve the stress (P<0.001), and more non-smokers know that when a pregnant woman smokes, it can cause the lack of supply of Oxygen{P<0.01). 9. Smoking group and former smoking group have more positive attitude towards smoking than non-smokers and tend to agree to their boy and girl friends' smoking(P<0.001).

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2004년도 춘계학술발표회
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• pp.453-460
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• 2004

To prevent penetration of rainwater into the landfill site is the main purpose of the final cover in landfill sites. Conventional designs of landfill covers uses geotextiles such as geomembrane and GCL, and clay liners to lower the permeability of final covers of landfill sites. However, differential settlement and the variation of temperature in landfill sites cause the development of cracks or structural damage inside the final cover and it is also difficult to obtain clay - the main material of the compacted clay liner in Korea. Thus the former final cover system that suggests geomembrane and GCL or compacted clay liner has several limitations. Therefore, an alternative method is necessary and one of them is the application of SRSL(self-Recovering Sustainable Liner) material. SRSL is two different layers consist of individual materials that react with each other and form precipitates, and with this process lowers the permeability of the landfill final cover. SRSL generally is made up of two layers, so that when a internal crack occurs the reactants of the two layers migrate towards the crack and heal it by forming another liner. In this study the applicability of SRSL material for landfill final cover was examined by performing; (1) jar test to verify the formation of precipitate in the mixture of each reactants, (2) falling head test considering the field stress in order to confirm the decrease of permeability or prove that the hydraulic condctivity is lower than the regulations, (3) compression tests to judge weather if the strength satisfies the restricts for landfills, (4) freeze/thaw test to check the applicability of SRSL for domestic climate. In addition, the application of waste materials in the environmental and economical aspect was inspected, and finally the possibility of secondary contamination due to the waste materials was examined by performing elution tests.

• 한국환경과학회지
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• 제26권2호
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• pp.231-238
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• 2017

Rapid industrial development has led to a serious problem of pollution in the industrial sector. With the increasing social need for environmental protection, research on air pollution prevention equipment for reducing pollutants in industrial processes is actively being undertaken. The deterioration of existent, installed facilities, their increased emission rates, and the strengthening of the effluent quality standards make complying with permissible emission standards difficult. In fact, installing new electric precipitators or complementing existent facilities is inevitable. The expansion and complementation of the installed electrical precipitators have led to improvements in dust collection efficiency, shorter working times, and lower costs. Because of its easy installation and simple manufacturing process, the production method with the discharge electrode of an electric precipitator is widely used. The following conclusions were reached by classifying discharge electrodes into four types based on the production method and mutually comparing them by their dust collection efficiency. None of the four types used in this study were damaged by impact. However, we were able to confirm some strain from the compression sites of both type A and type B. Both type B and type C are expected to have greater dust collection efficiencies than the other models due to their large vibration transmissibility. Moreover, the high vibrational energy is expected to cause rapping damage during its operation. Particularly, in the case of type B, some of the strain was found at the end of the compression site. The coupling schemes of both type C and type D are out of vibration transmissibility. On the other hand, the ability to maintain straightness and solidity of the side is regarded as outstanding and stable. Type D has outstanding on-site workability, considering the presence of locking, structural stability, and work conditions. From these experiments, we determined that type C is the most ideal connection method of discharge electrode, considering its construction period of renovation. Type C is inferior to type D with regard to on-site workability. However, type C has outstanding dedusting transmission with regard to the straightness, solidity maintenance, and vibration of shearing stress.

• 대한치과의사협회지
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• 제52권12호
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• pp.744-752
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• 2014

There are many causes of oral mucosal diseases, so accordingly, there are various treatments available. The most commonly used agents include adrenocortical hormones, antifungals, antivirals, antibacterials, and immunosuppressants. However, it must also be noted that improving oral hygiene and nutrition, and reducing stress are effective in symptom relief. Furthermore, patients with existing diseases of the oral mucosa should avoid behavior that may cause an increase in pain. Unfortunately, many patients are unaware of the activities that may lead to increased pain and therefore do not avoid these activities. The aim of this study was to investigate and analyze the behavior of patients with oral mucosal disease with regard to activities that led to increase pain. This cross-sectional study was performed on a sample of patients with oral mucosal disease selected from the Oral Medicine Clinic of the Pusan National Hospital during March to August 2013. These patients were randomly selected. From a total of 479 patients, 116 patients with mucosal disease were selected and 73 fully completed questionnaires were included in the analysis. Data were collected by using self-completed questionnaires. The results were as follows: Mean score of Question 13 (Not smoking) is $2.47{\pm}1.11$. Mean score of Question 11 (Not drinking alcohol or not using mouthwash containing alcohol) is $2.22{\pm}1.15$. The other questions resulted in scores lower than 1.5. The answers to the questions were scored according to the following assigned numerical values: not keeping = score of 0; little keeping = score of 1; often keeping = score of 2; always keeping = score of 3. In conclusion, patients with oral mucosal diseases unknowingly engage in activities that result in an increase in pain. Therefore, they need to be educated about how to behave to protect oral mucosal lesion.

• 생명과학회지
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• 제20권5호
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• pp.639-643
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• 2010

비육우의 공장, 회장 및 결장의 특징적 괴사 출혈성 장염 증상은 폐사 증후군과 관련이 있는 것으로 인식되고 있다. 특히 젖먹이 송아지들이 폐사 증후군에 가장 영향을 받는데, 포유시 송아지에게 과식을 시키거나, 비위생적 초유 급유, 체온 하강 및 스트레스는 장독혈증 발생의 원인들이다. 2006년 7월 중 경북 영천 지역에서 축우의 폐사가 발생하였다. 식욕부진, 의기소침, 간헐적인 설사 및 경미한 호흡 곤란을 제외하고는 특별한 임상 증상은 없었으나, 조직학적 소견에 의하면, 심장, 신장, 간, 비장 및 임파선을 포함한 각종 기관에서 globular leukocytes 의 침윤뿐 아니라 핵내 봉입체가 현저하게 나타났다. 비장과 림프조직에서는 림프 괴사와 림프구 괴사로 인한 'starry sky appearance'를 나타내었다. 소장 점막 하에서는 다량의 globular leukocytes와 호산 구의 침윤과 함께 호 염기성 세포 집단이 관찰되었다. 봉입체가 있는 소장 조직의 단면은 그램 염색에 대해 조직 화학적으로 양성 반응을 나타내었다. 결론적으로, 비축우의 폐사 원인은 조직학적 및 조직화학적 분석 결과를 근거로 Clostridium perfringens D 형균에 의한 장독혈증으로 진단되었다.