• Clinical and Experimental Pediatrics
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• v.59 no.5
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• pp.205-211
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• 2016

Idiopathic nephrotic syndrome (INS) in children is characterized by massive proteinuria and hypoalbuminemia. Minimal change nephrotic syndrome (MCNS) is the most common form of INS in children. The pathogenesis of MCNS still remains unclear, however, several hypotheses have been recently proposed. For several decades, MCNS has been considered a T-cell disorder, which causes the impairment of the glomerular filtration barrier with the release of different circulating factors. Increased levels of several cytokines are also suggested. Recently, a "two-hit" theory was proposed that included the induction of CD80 (B7-1) and regulatory T-cell (Treg) dysfunction, with or without impaired autoregulatory functions of the podocyte. In contrast to the well-established involvement of T cells, the role of B cells has not been clearly identified. However, B-cell biology has recently gained more attention, because rituximab (a monoclonal antibody directed against CD20-bearing cells) demonstrated a very good therapeutic response in the treatment of childhood and adult MCNS. Here, we discuss recent insights into the pathogenesis of MCNS in children.

• Journal of Korea Multimedia Society
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• v.11 no.9
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• pp.1245-1257
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• 2008

The establishment of a production pipeline imported 30 computer graphics is suggested in this paper to improve the efficiency of existing production pipeline of clay animation. The point is that the process of building clay characters that remains labor intensive among the existing procedures is replaced by the process of creating computer generated characters. In order to create characters out of clay by means of 30 computer graphics, a diffuse map and displacement map are made of an oil-based clay according to the UVW coordination of polygon modeling, which is the same color and kind of clay used to make a clay character. In addition, a panoramic HDRI recording system is developed to record the lighting information of shooting environment for miniature sets, which is imported in 3D computer graphic tools as digital light source. On account of the new production pipeline, a hyper realistic rendering image can be produced, and at the same time it improves the traditional pipeline of stop motion animation that is know-how based procedure of a complete artist by the engineering approach to the automatic process.

• Journal of the Korean Society for Railway
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• v.12 no.3
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• pp.427-436
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• 2009

This paper introduced Railway Network Design Problem (RNDP) to provide priority decisions on high-speed railway investment scenarios defined by various network segments and train systems. The RNDP optimizes the objective functions of minimize total travel time. Results show that the priority of high-speed railway investment is found to be East-west, West-coast, and South-coast line respectively. An entirely new line built with 400km/h is found to be the best alternative to East-west line. Regarding West-coast and South-coast line, the combined alternative of upgrading Geolla and Kyeonjon line with 200km/h and building a new line with 400km/h and 350km/h for remains of each line is the best.

• Journal of the Korea Safety Management & Science
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• v.10 no.4
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• pp.105-109
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• 2008

The purpose of this study is to distinguish the causes of broken glass on doors or windows when it is originally kept among the remains on the floor in fire site - whether it was broken due to heating or outer power-through test and characteristics of the broken plane including the pattern on the plane. Addition to it, the study tries to find characteristics to judge the point and direction of breakdown through the analysis of glass broken by outer power. With two assumed causes - a) breakdown due to heating and b) breakdown due to outer power-3 pieces of glass plates ($30cm{\times}30cm{\times}5mm$) were tested for each case, getting the results as following: First, for the glass broken due to the change of temperature, the broken plane is of slow and smooth curve without any pattern. Second, for the glass broken due to outer power, with the impact point as the center, the glass shows breakdown of radial type and the side shows breakdown of near-perpendicular type. The far the broken piece is from the impact point, the bigger the size is. The broken piece at the impact point is of long triangle type and the two long planes of the triangle shows semi-arc with the center of breakdown point and the other plane shows opposite pattern. Third, when glass that is damaged by outer power is heated, damaged forms and side patterns of the glass that is damaged by outer power are heated and disappeared.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.26 no.2
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• pp.241-268
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• 2015

Since 2008, the Presidential Committee on Library and Information has conducted 'National Library Management Evaluation,' and almost all of the public libraries have participated in the evaluation. In order to find the effect of the Evaluation on the public libraries, this study analyzed four years of the performance scores (2010~2013) during the period of the $1^{st}$ National Library Development Plan 2009~2013, which used the same measurement, were analyzed by the size groups and regions. The results indicated positive effect on the quality of the internal process such as planning and collection building. Yet attainment gab remains between metropolitan and the other regions, and also different relationship exists between input and attainment among the public library size groups. It suggested the policy development considering the library size and the regional difference.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2013.10a
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• pp.1041-1043
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• 2013

As the mobile device supply is increasing currently, the era of N mobile devices per person has opened. Types of mobile devices and OS are increasing continuously. Samsung and Intel are developing TIZEN, the OS mobilized by UBUNTU of Linux is going to be released as well as the market share of Google's Android and Apple's IOS remains above 90%. However, it is a reality that there are not specific technologies or systems which can share files between different OS. Despite of technologies such as Bluetooth and WiFi Direct, constraints are shown in device compatibility and file formats. In this paper, we have studied how to share files between OS as well as mobile devices, and to share files in a wireless LAN environment of heterogeneous variety. Future research includes the mobile phone integration server system that provides services such as introduction, management, maintenance, and repair in one-touch Mobile Server that spread and building are easy.

• International Journal of High-Rise Buildings
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• v.3 no.2
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• pp.99-106
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• 2014

This paper presents the determination of the structural system of the Changsha IFC T1 tower with 452 m in architectural height and 440.45 m in structural height. Sensitivity analyses are carried out by varying the location of belt trusses and outriggers. The enhancement of seismic capacity of the outer frame by reasonably adjusting the column size is confirmed based on parametric studies. The results from construction simulation including the non-load effect of structures demonstrate that the deformation of vertical members has little effect on the load-bearing capacity of belt trusses and outriggers. The elastoplastic time-history analysis shows that the overall structure under rare earthquake load remains in an elastic state. The influence of the frame shear ratio and frame overturning moment ratio on the proposed model and equivalent mega column model is investigated. It is found that the frame overturning moment ratio is more applicable for judging the resistance of the outer frame against lateral loads. Comparison is made on the variation of these two effects between a classical frame-core tube-outrigger structure and a structure with diagonal braces between super columns under rare earthquakes. The results indicate that plasticity development of the top core cube of the braced structure may be significantly improved.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.10
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• pp.743-750
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• 2016

In this research, the effects of the strength and stiffness of shear walls on the design strength of coupling beams are studied in the shear wall-coupling beam structural system widely used as the lateral-drift resistant system of high-rise buildings. The results show that the design strength of the coupling beams decreases with decreasing concrete strength and core wall thickness, but the shape remains unchanged. In all six models, the design strength of the coupling beams has the largest value at the 10~15th floors in a 40-story building. In other words, the design strength of the coupling beams has the largest value at 0.25H~0.375H where the inflection point exists. The thicker the walls, the smaller the change in the member forces. The thickness of the coupled shear walls has more influence on the design strength of the coupling beams than the concrete strength.

• Journal of the Regional Association of Architectural Institute of Korea
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• v.20 no.6
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• pp.41-46
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• 2018

The context of innovation in which we evolve today, subtracts us in a spacial reality and virtuality (digital) that aimed less and less to interact with natural processes which could converge to new possible relationships in the world. We constantly live in presence of fluctuations and imperceptible natural energies (wind, solar radiation, etc.) defined by flows, their own physicality, which remains without being virtual, elusive. This study first outlines how these energies already exploited within the framework of production, could be thought as interactive of our habitat's space dimension, as a prolongation of a physical and material environment built by men and for men, giving rise to new social, cultural dynamics, and making natural complexity of our space vivid, comprehensible with new visual and physical clues. In recent days, where lifestyles are changing, architecture no longer needs to limit its scope of creation to only built structures. Based on a deeper understanding of human and through new potential advanced technologies (kinetic system, etc), it is time to fundamentally diagnose what environments or devices contribute to our lives. Architecture becomes ${\ll}interface{\gg}$, step up its fundamental role, and newly defines the sturdy image and tectonics of existing environment, establishing a stance to search for a new typology. In the end, building will show two simultaneous and distinctive connections related to its physical existence: reality in its function and irreductibility, in its ability to forge new dynamic connections with its environment, hybridizing the spatial dimension to a new form of physicality, adaptive and incessantly flexible in the dimension time, becoming a vessel for ever changing contemporary lifestyles.

• Journal of architectural history
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• v.28 no.1
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• pp.25-34
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• 2019

"Stupa of Buddhist Monk, YeomGeo"(844) is known as the earliest Seon-stupa relic remains in Korean peninsula, from which, during late Silla and ealy Goryeo period, there were more than 30 of stupa was built on such canon. and became the well-known material culture in Seon Buddhism in late Silla period. In $9^{th}$ century, with the JeonDeong(delivering the light of Seon)from Tang to Silla, the culture of "GeonTapIpBi(building the pagoda and erecting stele)" was also moved in. And it was right after the style of monk's stupa had been methodically changed in china, from having the room in stupa for the corpse, named as "QuanShenSheLi", to the lessened stupa that contain the cremated. Analyzing the "Master ChengGuang's stupa"（807）and its stele, it can be found the correspondences of octagonal plan and the subjects of ornamentation to that of Stupas built in Silla, reveals they were made by the same canon. By the document in the stele, surmising the historical cause of alteration in Chan stupa, there was the most famous zen master ShenHui at the time, who has the most important role of making the NanZongChan to get the authenticity in Chan Buddhism. His reliqury was the first ${\acute{s}}ar{\bar{i}}ra$ casket discovered among Chan monks' relics, consequentially it was to influence to Chan cuture and size the monks 'stupa for his ${\acute{s}}ar{\bar{i}}ra$. The stupa of master ChengGuang, by its shape and geological location, is the lost piece in the Puzzle of Chan stupa culture between Silla and Tang.