• Journal of Periodontal and Implant Science
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• v.50 no.3
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• pp.159-170
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• 2020

Purpose: Immunization with Porphyromonas gingivalis heat shock protein 60 (PgHSP60) may have an immunoregulatory effect on atherogenesis. The aim of this study was to determine whether nasal immunization with a PgHSP60 peptide could reduce atherosclerotic plaque formation in apolipoprotein E knockout (ApoE KO) mice. Methods: Seven-week-old male ApoE KO mice were assigned to receive a normal diet, a Western diet, a Western diet and challenge with PgHSP60-derived peptide 14 (Pep14) or peptide 19 (Pep19), or a Western diet and immunization with Pep14 or Pep19 before challenge with Pep14 or Pep19. Results: Atherosclerotic plaques were significantly smaller in mice that received a Western diet with Pep14 nasal immunization than in mice that received a Western diet and no Pep14 immunization with or without Pep14 challenge. An immunoblot profile failed to detect serum reactivity to Pep14 in any of the study groups. Stimulation by either Pep14 or Pep19 strongly promoted the induction of CD4⁺CD25⁺ forkhead box P3 (FoxP3)⁺ human regulatory T cells (Tregs) in vitro. However, the expression of mouse splenic CD4⁺CD25⁺FoxP3⁺ Tregs was lower in the Pep14-immunized mice than in the Pep14-challenged or Pep19-immunized mice. Levels of serum interferon gamma (IFN-γ) and transforming growth factor beta were higher and levels of interleukin (IL) 10 were lower in the Pep14-immunized mice than in the other groups. Induction of CD25^- IL-17⁺ T helper 17 (Th17) cells was attenuated in the Pep14-immunized mice. Conclusions: Nasal immunization with Pep14 may be a mechanism for attenuating atherogenesis by promoting the secretion of IFN-γ and/or suppressing Th17-mediated immunity.

• Publications of The Korean Astronomical Society
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• v.24 no.1
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• pp.53-64
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• 2009

MIRIS is the main payload of the STSAT-3 (Science and Technology Satellite 3) and the first infrared space telescope for astronomical observation in Korea. MIRIS space observation camera (SOC) covers the observation wavelength from $0.9{\mu}m$ to $2.0{\mu}m$ with a wide field of view $3.67^{\circ}\times3.67^{\circ}$. The PICNIC HgCdTe detector in a cold box is cooled down below 100K by a micro Stirling cooler of which cooling capacity is 220mW at 77K. MIRIS SOC adopts passive cooling technique to chill the telescope below 200 K by pointing to the deep space (3K). The cooling mechanism employs a radiator, a Winston cone baffle, a thermal shield, MLI (Multi Layer Insulation) of 30 layers, and GFRP (Glass Fiber Reinforced Plastic) pipe support in the system. Optomechanical analysis was made in order to estimate and compensate possible stresses from the thermal contraction of mounting parts at cryogenic temperatures. Finite Element Analysis (FEA) of mechanical structure was also conducted to ensure safety and stability in launching environments and in orbit. MIRIS SOC will mainly perform Galactic plane survey with narrow band filters (Pa $\alpha$ and Pa $\alpha$ continuum) and CIB (Cosmic Infrared Background) observation with wide band filters (I and H) driven by a cryogenic stepping motor.

• Korean Chemical Engineering Research
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• v.53 no.2
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• pp.236-242
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• 2015

We present two data-driven modeling methods, partial least square (PLS) and artificial neural network (ANN), to predict the major operating and performance variables of a polymer electrolyte membrane (PEM) fuel cell stack. PLS and ANN models were constructed using the experimental data obtained from the testing of a 30 kW-class PEM fuel cell stack, and then were compared with each other in terms of their prediction and computational performances. To reduce the complexity of the models, we combined a variables importance on PLS projection (VIP) as a variable selection method into the modeling procedure in which the predictor variables are selected from a set of input operation variables. The modeling results showed that the ANN models outperformed the PLS models in predicting the average cell voltage and cathode outlet temperature of the fuel cell stack. However, the PLS models also offered satisfactory prediction performances although they can only capture linear correlations between the predictor and output variables. Depending on the degree of modeling accuracy and speed, both ANN and PLS models can be employed for performance predictions, offline and online optimizations, controls, and fault diagnoses in the field of PEM fuel cell designs and operations.

• Journal of Digital Contents Society
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• v.10 no.1
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• pp.61-71
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• 2009

While the broadband network and multimedia technology are being developed, the commercial market on digital contents as well as IPTV has been widely spreading. Especially IPTV is providing various useful services since it makes using multimedia contents easier and more convenient by combining the strong points of both TV and PC system. Until now, IPTV system has been focused on VoD service as a general usages. However, various IPTV services are recently demanded since they can have special features for some specific places and occasions. So in this paper, we propose a design of the download based IPTV system using user-specific channel management. At first, program contents previously scheduled by users are downloaded and are played at settop-box according to the prescribed time table. This system has some advantages of giving users easy access to any wanted media contents in anytime that is IPTV's characteristics. And we can increase stability of services by using time slot distributed download for contents. Because this service can be constructed and maintained at relatively low cost, we confirm that this service model is more suitable to some companies with small infrastructure and special purposes. Accordingly, in this paper, we look into necessary elements and define some protocols for system in order to help other developer build this system.

• Spatial Information Research
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• v.14 no.1 s.36
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• pp.163-176
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• 2006

The concept of 'spatial association' explains spatial distribution pattern of geographical phenomenon based on similarity with neighborhoods, as in the Tobler's Law of Geography: 'Everything is related to everything else, but near things are more related than distant things.' In this study, we develop a time-series exploratory analysis tool for discovering temporal patterns of spatial association by combining spatial statistics and geo-visualization, and thus present a possibility to support spatial decision-making process. As for the spatial proximity weight matrix indispensable to measuring global and local spatial association, we employ a variety of flexible weighting schemes using geometric characteristics of areal unit. In addition, we renovate the existing visualization methods for more effective understanding of the procedures and results of time-series analysis on spatial association: for instance, temporal parallel coordinate plot with box plot, animated map for spatial association, and 3D Moran scatterplot. The feasibility of our system is verified by time-series analysis experiments on the spatial association of land price fluctuation rate for all administrative units in Korea, $1995{\sim}2004$.

• Journal of the Korea Society of Computer and Information
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• v.11 no.5 s.43
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• pp.39-52
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• 2006

As accelerates the technical evolution of high-speed network and progresses the digitalization of broadcasting network, TV channel service through satellite/cable/terrestrial networks becomes more stable and mature. However, TV channel service using IP network such as IPTV is recently emerging. Especially, when it comes to current mosaic EPG(Electronic Program Guide) as a channel guide, the implementation of EPG via IP network is under developing. Furthermore, the personal target mosaic EPG is not provided at all in the IPTV. This paper proposes a construction method of mosaic system which can support fixed and personalized mosaic EPG using IP network for viewers. The fixed mosaic EPG is made several steps as follows ; First, H/E generates several mosaic A/V streams. Then, which are transmitted to the STB in terms of multicasting via IP network. Finally, mosaic EPG is displayed on TV through STB. In addition, this paper describes a construction model of the personalized A/V mosaic EPG that represents each person's favorite channels according to their tastes and interests. As for the contributions. The TV channel guide using IP network enable viewer to select channel more easily with practical adaptation of multi-channel expansibility and sufficient usability. In addition, through personal mosaic EPG, a number of viewers can compose their own mosaic EPG and enjoy a variety of channel easily in accordance with their preferences. Finally, the personal mosaic EPG can prohibit non-adult users from connecting adult-only contents more efficiently.

• Nuclear Engineering and Technology
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• v.3 no.2
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• pp.65-75
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• 1971

The gamma-ray shielding effects of magnetite concretes have been measured using a broad beam Co-60 gamma-ray source. Mathematical formulae for a trans-mission ratio-to-shield thickness relation were derived from the attenuation curve obtained experimentally and are I (x) = I (ο) exp(-$\mu$X) exp(1.03$\times$10$^{-1}$ X-3.38$\times$10$^{-3}$ X$^2$＋5.29$\times$10$^{-5}$ X$^3$) when X< 20 cm, I (x) =I (ο) exp(-$\mu$X) exp(4.66$\times$10$^{-2}$ X＋2.12$\times$10$^{-1}$ ) when X＞20 cm. Here I (x) is radiation intensity after passing through a thickness X of absorber, I(o) is the initial radiation intensity, $\mu$ is the linear attenuation coefficient of magnetite concrete and is given by (0.0532$\rho$＋ 0.0083)$^{4)}$ $cm^{-1}$ / in accordance with an earlier study, and X is the thickness of absorber. In addition, a model shield which is a rectangular magnetite concrete box with walls of 8cm thickness walls and internal demensions of 40$\times$40$\times$40 cm was constructed and its shielding effect has been measured. The emergent radiation flux appears to be greater with this configuration than with a slab shield of equal thickness.

• Proceedings of the Optical Society of Korea Conference
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• 2005.07a
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• pp.28-29
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• 2005

본 논문에서는 MEH-PPV와 DFPP의 폴리머 물질을 이용하여 photovoltaic device가 제작되었고, 그림 1에 두 물질의 분자 구조가 보여진다. Photovoltaic cell의 전기-광학적 특성은 활성층의 폴리머 물질에 의해 결정된다. 이러한 특성을 알아보기 위해서 홉수 스펙트럼이 측정되었다. DFPP는 chloroform, chlorobenzen, THF, acetone에 잘 녹았으며, 본 논문에서는 chloroform이 용매로 사용되었다. 제작 공정은 다음과 같다. 인듐 주석 산화물 (ITO)이 증착된 유리기판은 photolithography 공정을 거친 후, 왕수(HNO$_{3}$ + HCL)로 식각됨으로서 전극의 패턴이 제작되었다. 그리고 ITO 전극 패턴 된 유리기판 위에 PEDOT (CH8000, Baytron)이 코팅된 후 Ar이 주입되는 Convection Oven을 이용하여 120$^{\circ}$C에서 2시간 동안 열처리되어 수분이 제거되었다. 활성층에는 MEH-PPV와 DFPP가 9:1과 2.33:1로 혼합된 폴리머가 사용되었고, 이것은 0.3 %w.t.가 되도록 chloroform에 넣어 5시간 동안 스핀바를 돌려서 용해되었다. 이 용액은 ITO 전극 패턴이 형성된 글라스 위에 3000 rpm으로 45 초간 스핀코팅 되었다. 이 때 얻어진 유기물 박막층은 80$^{\circ}$C의 Ar이 주입되는 convection oven에서 3시간 동안 경화되었다. 경화된 단층 유기물 박막층 위에 Li-Al이 1000 ${\AA}$의 두께로 증착되어 전극이 형성되었고, 이후 질소가 채워진 globe box에서 소자는 encapsulation되어 산소와 수분에 대한 영향으로부터 차단되었다. 상기의 공정으로 제작된 소자의 박막구조는 그림 2에서 보여진다. 그림 3은 MEH-PPV와 DFPP를 혼합했을 때의 흡수 스펙트럼이다. 최대 흡수 파장은 511 nm였다. 그리고 photovoltaic cell의 V-I 특성 결과가 그림 4와 같이 측정되었다. 측정에서는 300${\sim}$700 nm의 파장대를 갖는 태양광 모사계가 사용되었고, 셀의 면적은 10 mm$^{2}$였다. 그림 5의 I-V 특성으로부터 MEH-PPV와 DFPP가 9:1 로 혼합했을 때보다 2.33:1 로 혼합했을 때, photovoltaic device의 효율이 향상됨을 확인할 수 있다. 빛이 75 mW/cm$^{2}$ 의 세기로 조사될 때 9:1과 2.33:1로 혼합된 소자의 open circuit voltage (V$_{oc}$)는 비슷하지만, short circuit current Density (J$_{sc}$)는 각각 -1.39 ${\mu}$A/cm$^{2}$ 와 -3.72${\mu}$A/cm$^{2}$ 로 약 2.7배 정도 증가되었음을 볼 수 있다. 이러한 결과를 통해 electron acceptor인 DFPP의 비율이 높아질수록 photovoltaic cell의 conversion efficiency가 더 크게 됨을 확인할 수 있다. 그러므로 효율이 최대가 되는 두 폴리머의 혼합 비율이 최적화되는 조건을 찾는 것은 매우 중요한 연구가 될 것이다.

• Journal of the Society of Naval Architects of Korea
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• v.28 no.1
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• pp.150-168
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• 1991

A practical procedure for the ultimate compressive strength-based safety and reliability assessment of the double skin upper deck structure is described. The external compressive stress acting on the upper deck structure which is due to the still water and wave-induced sagging moment is approximately estimated by using the existing rule of classification society. The ultimate compressive stress of double skin structure under the action of sagging moment is analyzed by using idealized structural unit method. Here an idealized plate element subjected to uniaxial load is formulated by idealizing the nonlinear behaviour of the actual element taking account of the initial imperfections in the form of initial deflection and welding residual stress. The interaction effect between the local and global failure in the structure is also taken into consideration. The accuracy of the present method is verified comparing with the present solution and the existing numerical and experimental results for unit member and welded box columns. The safety of the structure is evaluated using the concept of conventional central safety factor and the reliability assessment is made by using Cornel's MVFOSM method. The present procedure is then applied to upper deck structure of double skin product oil carrier. The influence of the initial imperfections and the yield stress of the material on the safety and reliability of the structure is investigated.

• Journal of the Korean Society for Railway
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• v.18 no.3
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• pp.261-269
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• 2015

To overcome the weaknesses of viaduct bridges and the non-economic efficiency of underground LRT, the study of near-surface railway systems is in progress. To apply a box structure to the low depth transit, a connection joint to precast modules are very important when applying precast modular structures to replace temporary structures. In this study, wall to wall connections were applied in diverse cases such as rebar connections, guiding structures that were used to fit the verticality of precast walls during construction, and non-reinforcement structures used only for waterstop. Experimental performance verification was carried out for the bending, shear and splitting of the wall to wall connection. Precision of construction joints between wall to wall was identified as a factor that influenced the structural performance of the precast wall. A structure that can serve as a guide during the vertical insertion of a wall is confirmed for the most suitable case, but it will be necessary to modify this structure for detailed cases.