• Journal of Acupuncture Research
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• v.27 no.5
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• pp.1-12
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• 2010

Objectives : This study was designed to evaluate the antidiabetes effects of Cinnamomum cassia and Aconitum carmichaeli in type II diabetes mellitus model mice. Methods : The experimental animals were divided into 3 groups and treated for 50 days as follows:control group, pharmacopuncture group and extract administration group. The effects of Cinnamomum cassia and Aconitum carmichaeli were observed by measuring body weight, blood glucose, insulin, insulin immunoreactivity of the pancreas and subpopulation of splenocytes. Results : Cinnamomum cassia sample groups were reduced a little body weight than control group. Glucose level of extract administration group lowered than control and pharmacopuncture group. Insulin immunoreactivity of Aconitum carmichaeli extract group appeared more effective than control and pharmacopuncture group. Conclusions : This study shows that Cinnamomum cassia and Aconitum carmichaeli have a distinct antidiabetes effect in type II diabetes mellitus model.

• Journal of Korean Biological Nursing Science
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• v.8 no.2
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• pp.29-39
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• 2006

The aim of this study was to examine the effect of telephone follow-up on glycemic control, lipid profiles. and treatment method in diabetic patients with depressive symptoms over one year follow-up period. Twenty-two diabetic patients attended the structured diabetes education program between March 2004 and February 2005 and completed a questionnaire using the Beck Depression Inventory(BDI) to measure depressive symptoms. The patients showed depressive symptoms with the criterion being a BDI score at least 16. The intervention was applied to the telephone follow-up for one year. Data were analyzed using Wilcoxon signed rank test and McNemar test. The patients decreased their mean glycosylated hemoglobin(HbAlc) levels by 1.9%(p=0.001). There was a significant mean change in the fasting blood sugar(FBS) level, with a mean change of -61mg/$d{\ell}$(p=0.008). These findings indicated that the telephone follow-up may be effective in the HbAlc and FBS control.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.2
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• pp.234-240
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• 2012

The purpose of this case-control study is to investigate the relationship between storke and stroke risk factors, such as family history and past history. The case-control study over clinical data registered from Daejeon Oriental Medical Hospital in the period of November 2006 to July 2010. Study subjects consisted of 108 patients with acute stroke within 1 month as the case group (Cases) and 108 people who visited hospital for health care as the genreral control group (Controls). The participants had been interviewed by residents to find out their family history and past history. Their blood was taken to check the blood lipid level and liver function. 1. The people whose family history included cerebrovascular accident had more probability of stroke than the people who did not have cerebral vascular accident as their family history. 2. The people who suffered from hypertension had more probability of stroke than the people who did not suffer from hypertension. 3. The people who suffered from diabetes mellitus had more probability of stroke than the people who did not suffer from diabetes mellitus. Based on this study, the people who had cerebral vascular accident as their family history should thoroughly treat their blood pressure and blood sugar level to prevent the cerebral vascular accident.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.14 no.1
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• pp.44-52
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• 2007

Purpose: This study was done to investigate the effect of Tai Chi Qigong exercise program on insulin resistance and blood glucose in patients with type 2 diabetes. Method: This was a quasi-experimental study used a non-equivalent control group pretest-posttest design. Participants included 39 patients with type 2 diabetes mellitus patients (ages between 40-70)(experimental group, 19, control group, 20). The Tai Chi Qigong exercise program consisted of 5 minute warming up, 30-minute main exercise, and 5 minute cooling down, and was conducted twice a week for 10 weeks. The outcome variables were insulin resistance (proinsulin, C-peptide, insulin, insulin sensitivity index) and blood glucose (fasting, post prandial 2hr, HbA1c). Data was analyzed using ANCOVA, with pre-test values as covariates, to examine difference between pre and post measures between the two groups. Results: The Tai Chi Qigong was effective in lowering postprandial 2hr blood glucose. Conclusion: Twice a week 10 week-Tai Chi Qigong exercise seems to be too short to improve insulin excretion or resistance, and fasting blood sugar and HbA1C in patients with type 2 DM. A Tai Chi Qigong program at least 3 times per week or longer is recommended.

• The Journal of Pediatrics of Korean Medicine
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• v.21 no.1
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• pp.253-270
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• 2007

Objectives : This study has been carried out to understand the effect of Cimicifugae Rhizoma and Seungmagalgeuntang on the hyperglycemic mice induced with Streptozotocin(STZ). Methods : The 60mg/kg of STZ was fed into mice twice by 24 h interval and then 120mg/kg STZ was fed again 3 days after the earlier feeding, Control group was administered mice with 0.9% saline(2mL/kg/day), and experimental groups were administered Cimicifugae Rhizoma extract(CA group, 10mg/kg/day; CB group, 30mg/kg/day) or Seungmagalgeuntang(SA group, 10mg/kg/day; SB group, 30mg/kg/day) after hyperglycemic induction for 6 weeks. Results : The body weight of experimental groups higher than control. The blood glucose concentration of the control group increased continuously reaching to 298.9 mg/dL after 6 weeks, however, significantly(p<0.01 or p<0.05) decreased in the SA and SB groups compared with control group. Blood insulin level significantly(p<0.01) increased in the experimental groups. The activities of SOD and catalase were more decreased in the experimental group than control group compared with normal group. In the point of pancreatic immunohistochemical change, the experimental group's pancreatic islets have increased and enlarged and the concentration of insulin-positive beta cells has also increased, comparing with the control group. Meanwhile forms of nucleus and mitochondria in the experimental group's hepatic cells were almost similar to the normal group. Conclusion : The result from the six weeks of observation demonstrates that the extracts from Cimicifugae Rhizoma and Seungmagalgeuntang have positive effects on lowering blood sugar level and elevating insulin concentration. The extract had also effects on recovering and regenerating pancreatic tissue of the hyperglycemic mice induced with STZ. At the same time, it had a protective effect against hepatotoxicity as well.

• Korean Journal of Food Science and Technology
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• v.12 no.1
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• pp.77-81
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• 1980

The effect of dietary vegetable oils, sesame, perilla, soybean and rice bran oils, on the blood cholesterol level of rabbit was examined using isocaloric and isonitrogenous diets. The gain in body weight, liver weight, serum and liver cholesterol levels, globulin, blood sugar and acid phosphatase activity in relation to cholesterol level were studied. The results are summarized as follows : 1. The gain in body weight (g/day) of rabbit was 16.3 for control, 15.3 for A, 18.3 for 15.3 for A, 18.3 for B, 15.3 for C and 18.1 for D groups. 2. Liver weight of the control A, B, C and D groups were 30.35, 37.25, 38.25, 31.05 and 39.54, respectively. 3. Serum cholesterol levels (mg/100 ml serum) of the control, A, B, C, and D groups were 71.5, 112.0, 110, 93 and 96 respectively. 4. Liver cholesterol levels (mg/100 ml liver fat) of the control, A, B, C and D groups were 255, 292, 255, 317 and 195 respectively. 5. The contents of alpha-1-globulin for control was 0.60 %, for C, 0.35 % and for D groups, 0.32% of total globulin. The content of alpha-2-globulin for control was 0.68 % of total globulin and for D, 0.26 % of total globulin. 6. The contents of blood glucose (mg/100 ml) of the control, A, B, C and D groups were 40.34, 22.37, 77.0, 28.6 and 34.1 respectively. 7. Acid phosphatase of the control, A, B, C, and D groups were 3.95, 4.52, 3.98, 4.55 and 4.53 nM/hr/l serum respectively. 8. According to the regression and correlation in coefficient in blood components of rabbit, there were positive correlations between serum cholesterol and alpha-1-globulin, and between liver cholesterol and gamma-globulin.

• Korean Journal of Community Nutrition
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• v.18 no.2
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• pp.134-141
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• 2013

This study was conducted to investigate instant coffee-mix intakes and its relations with anthropometric measurements, nutrient intake, and blood lipid in Gangneung and Samcheok residents. Coffee-mix is a mixture of instant coffee, sugar and coffee-creamer. It is a standardized convenience food in Korea. Recently, Koreans appear to consume too much of instant coffee-mix. The respondents of this study were 218 Koreans (Gangneung region 133, Samcheok region 85). The average age was 56.0 years (male), 57.5 years (female). They were divided into 2 groups, the instant coffee-mix drinkers and the non-drinkers. The nutrient intake and anthropometric measurements and their relations with coffee-mix intakes were analyzed (nutrient intakes were calculated by converting per 1,000 kcal and adjusted by age, region). As for male, body fat was significantly higher in coffee-mix drinkers (18.1 kg, 25.0%) than in non-drinkers (17.1 kg, 23.8%). In the case of females, serum triglyceride was significantly higher in coffee-mix drinkers (109.1 mg/dL) than in nondrinkers (102.9 mg/dL). Coffee-mix intakes and coffee-mix's contributions to energy were higher for participants from Samcheok (21.2 g, 4.7%) than those from Gangneung (16.6 g, 3.4%). In addition, for Samcheok, coffee-mix's contribution to energy was significantly higher in male (5.6%) than in female (4.2%). Coffee-mix intakes and energy contribution of coffee-mix were not significantly correlated with anthropometric measurements. Only HDL-cholestrol showed significantly negative correlation with coffee-mix's contributions to energy. Based on the above results, we conclude that usual instant coffee-mix intake may increase intakes of sugar and fat and exert negative effects on serum lipids. Therefore, it is needed to control too much instant coffee-mix intake in the dietary management of rural residents.

• Journal of Home Health Care Nursing
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• v.19 no.1
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• pp.74-82
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• 2012

Purpose: The aim of this study is to evaluate the effects of community based chronic disease management program for managing hypertension and diabetes mellitus. Method: The subjects of this study were 1,000 clients, who participated in a city community based chronic disease management program. The data were collected by a phone survey directly, and selected from DB of community based chronic disease management program, indirectly. The data were analyzed by the STATA program, using descriptive statistics, t-test, and Multiple regression analysis. Results: The mean score of knowledge of hypertension was 4.33 and diabetes mellitus was 2.52. The affecting factors of knowledge of hypertension were the clinic visiting point and blood sugar. However, the affecting factors of knowledge of diabetes mellitus was core lab point, diastolic blood pressure, and blood sugar. Conclusion: the results of this study showed that knowledge of hypertension increased with higher level of education, and younger ages, while knowledge of diabetes mellitus increased with higher level education, more core lab point, younger ages, and in males. Therefore, to control the chronic diseases more effectively in a community, it is important to develop a more systematic education and self- managing programs, using collaboration of health centers and local clinics.

• Korean Journal of Food Science and Technology
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• v.34 no.3
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• pp.487-492
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• 2002

Low-fat and sugar-free (LFSF) cookies were developed for patients with metabolic syndrome X, such as obesity, diabetes, coronary heart disease, and hypertention, using artificial sweeteners (mixture of aspartame and saccharin), pectin and herb extracts such as Polygonatum Odoratum (Mill) Druce, Schizandrae Fructus and Lycii Fructus, without sugar and fats. LFSF cookies were composed of 7.5 : 1 of aspartame and saccharin, 5% pectin, 49% protein, and 5% herb extracts, with reduced fat level. The values for area under the curve in oral glucose tolerance tests were significantly lower in 90% pancreatomized-(Px, n = 8) and sham - operated (Sham, n = 8) rats which consumed LFSF cookies, than the control, which consumed regular cookies. Blood glucose levels were higher and the peak levels were significantly lower in the LFSF cookies group than the control group of Px and Sham rats. Blood glucose levels of healthy female college students (n = 10) at 30 and 60 min after the consumption of 30 g LFSF and regular cookies were not different, but they were significantly lower in the LFSF-cookies group in diabetes patients (n = 10). In conclusions, LFSF cookies was considered as a good snack for diabetic patients.

• Journal of Korean Academy of Nursing
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• v.20 no.2
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• pp.174-184
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• 1990

In order to determine the effect of individual patient teaching through home visiting on compliance with sick role behavior and the blood sugar level in diabetic patients, to determine if the effectiveness of the education was still present four year later and to inquire as to the effective time for a repeat education program this study was done through two quasi-experimental researches. The subjects consisted of 52 diabetic patients. The results of the study may be summarized as follows ; 1. Hypothesis I, in which the compliance with sick role behavior, the knowledge on diabetes and the health belief of the experimental group who received a diabetic education program will be higher than those of the control group who didn't receive the diabetic education, was supported by both studies in 1984 and 1988, confirming the effect on diabetic patients of the individualized education through home visiting ; In the 1984 study : Compliance(t＝-11.7, p＜.001) Knowledge(t＝-5.41, p＜.001) Health belief(t＝-4.74, p＜.001) In the 1988 study : Compliance(t＝-4.85, p＜.001) Knowledge(t＝-2.85, p＜.01) Health Belief(t＝-2.99, p＜.005) 2. The Hypothesis II, the blood sugar level of the experimental group will be lower than that of the control, was rejected in both studies, 1984 and 1988. 3. The Hypothesis III, the compliance, knowledge and health belief of the expermental group who received the education program in 1984 will not last till 1988, was supported in part, in compliance and health belief, but not in knowledge. In conclusion those who received the education program twice with an interval of 2 weeks, 4 years ago still had knowledge of diabetes but compliance and health belief had disappeared.