• 한국임상수의학회지
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• 제34권3호
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• pp.222-224
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• 2017

A retrospective study was designed to determine whether there were any differences in prepartal blood biochemical parameters between cows developed subclinical ketosis (SCK) and non-SCK cows. Data on blood biochemistry from 33 Holstein parturient cows (15 SCK and 18 non-SCK cows) in one farm for one year, were compared. Plasma beta-hydroxybutyrate, non-esterified fatty acid and glucose concentrations were utilized in the diagnosis of SCK and showed significant differences between SCK and non-SCK cows after calving. Before calving, however, only plasma total cholesterol concentration in SCK cows was significantly lower than that in non-SCK cows. Consequently, it seems that lower plasma total cholesterol concentration before calving is related to the occurrence of SCK immediately after calving.

• 한국작물학회지
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• 제58권4호
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• pp.443-450
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• 2013

Effects of newly developed functional rice grains Goami (high-amylose rice) and Nokwon (green-kerneled rice) on the glucose metabolism and antioxidative defense system in C57BL/6N mice under high fat diet condition were investigated. Animals were randomly divided into five groups (n = 8) and given experimental diets for eight weeks: normal control diet (NC), high fat diet (HF), and high fat diet supplemented with white rice (HF-WR), Goami rice (HF-GR), and Nokwon rice (HF-NR). At the end of the experimental period, the HF group exhibited markedly higher blood glucose level, insulin concentration, plasma lipid peroxidation and lower hepatic glycogen concentration than that exhibited by NC group. However, diet supplementation of Goami and Nokwon suppressed the high fat diet-induced hyperglycemia and oxidative stress through inhibition of the glucose-regulating enzymes and enhancement of the antioxidant enzymes activities. The results illustrate that the new functional rice Goami and Nokwon may be useful in the development of functional foods with preventive effect against high fat diet-induced hyperglycemia and oxidative stress.

• Journal of Nutrition and Health
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• 제31권8호
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• pp.1226-1234
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• 1998

The aim of the study was to determine whether vitamin E supplementation in three experimental model rats with impaired glucse tolerance could change serum insulin concentration and lipid distribution. The three groups were adult(AS) and neonatal (NS) streptozotocin-induced groups, and a high sucrose diet(HS) group. Each group was divided into control and vitamin E supplementatino groups at the age of 9 weeks. The level of vitamin E supplementation was 5g/kg diet. Blood and organ samples were taken at 5 and 10 weeks and were examined for changes in the level of serum insulin, glucose, lipids, liver lipids, and oxidative status. Vitamin E supplementation significantly reduced serum insulin in the HS group and caused the significant beneficial changes in serum lipids and triglycerides in As grouop at 10 weeks . In all groups, serum vitamin E was increased and malondialdehyde(MDA) in serumand liver were decreased significantly by vitamin E supplementation. The results suggest that vitamin E supplementation improves lipid distribution in adult streptozotocin-induced rats and serum insulin concentration in high sucrose diet-induced rats. Vitamin E might prevent on reduce oxidative injury in all experimental model rats with impaired glucose tolerance.

• Toxicological Research
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• 제11권2호
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• pp.199-203
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• 1995

The focus of this study was to investigate that cellular parameters and glucose uptake might be altered by extracellular calcium and starvation. Addition of 1 mM $Ca^{++}$ to hepatocytes (equalling to the free calcium concentration of blood) significantly increased intracellular $Na^+$ and decreased $Na^+$ & LDH leakage. This pertains to the hepatocytes of control rats as well as those of rats fasted for 24 and 48. hr. These effects might be come from the membrane-stabilizing effects of calcium. But calcium had no effects on cell volumes, superoxide-formation and glucose uptake. Actually hepatocytes of starved rats showed changes in several cellular parameters. Starvation increased LDH leakage, glucose uptake and the total concentration of $Na^+$ and $Na^+$ whereas it markedly decreased cell volumes. Since total tonicity remained unchanged, intracellular $Na^+$ and $Na^+$ could contribute to a higher share of total osmolarity in starvation. Starvation increased the cytoplasmic pH because $R-NH^{3+}$ions and their corresponding counterions disappeared. This increase may be related to suppress the protonization of amino groups in proteins. Starvation decreased hepatic glycogen, a major compound that affects cytosolic volume of hepatocytes. The data indicate that starvation increases the glucose transport activity. The possible molecular basis will be discussed.

• 동의생리병리학회지
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• 제18권5호
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• pp.1456-1462
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• 2004

This study was carried out to understand the effects of Bambusae Caulis in Liquamen manufactured by different production facilities on blood glucose of the mice induced with streptozotocin. Filtered Bambusae Caulis in Liquamen manufactured by two different facilitiesproduction process were used. The physiochemical properties of filtered Bambusae Caulis in Liquamen manufactured by two different facilities(300L×300W×400H and 700L×700W×800H electric furnace) were compared. Furthermore, the effects of filtered Bambusae Caulis in Liquamen were observed in terms of blood glucose, BUN and AL T in the mice induced with streptozotocin. The results were as follows : The pH value was the highest in L-BCL(E)B(pH 2.83) between manufactured by two different facilities. The L-BCL(E)B which observed low values of Hunter's color values show decreased concentration of methanol and phenolic compounds. The blood glucose contents was decreased in the experimental groups compared with the control. The amount of BUN and ALT did not show any differences between control and experimental group.

• Asian-Australasian Journal of Animal Sciences
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• 제22권7호
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• pp.984-992
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• 2009

The objective of this study was to determine the effects of milk supplemented with Sel-Plex on thyroid hormones, rectal temperature, plasma glucose and cholesterol concentrations, and body weight in suckling calves. Ten Holstein suckling male calves of approximately 1 month of age were selected and randomly allocated to one of two groups and fed either unsupplemented milk (control) or milk supplemented with 0.3 mg/kg DM Se from Sel-Plex (treated). The animals received treated milk and free choice starter for two months. Dry matter intake for each individual animal was recorded daily throughout the study. The calves were weighed and blood samples were taken weekly. Plasma concentrations of triiodothyronine ($T_{3}$), thyroxin ($T_{4}$) and $T_{3}$-Uptake were determined using radioimmunoassay kits. Plasma cholesterol and glucose concentrations were determined by enzymatic-colorimetric methods. Rectal temperature was recorded at blood sampling time. During the experiment, ambient temperature and relative humidity were recorded at the time of blood sampling and every four hours. Treatment significantly (p<0.01) affected the concentration of $T_{3}$, free $T_{3}$ index ($FT_{3}I$) and ratio of $T_{3}$:$T_{4}$ in plasma. The plasma concentrations of $T_{3}$ in treated calves were 33% higher than in the control. The plasma concentrations of $T_{4}$ (p<0.05), glucose (p<0.01) and cholesterol (p<0.01) were decreased in the treated group. Calves fed Sel-Plex had higher rectal temperature (p<0.01). Plasma free $T_{4}$ index (FT4I) did not differ significantly between the two groups. An increase in body weight was observed (p<0.09) in the treated group. The results indicated that milk fortified with Sel-Plex could increase tissue conversion of $T_{4}$ to $T_{3}$ and therefore improve thermometabolism in suckling calves.

• 한국동물위생학회지
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• 제39권3호
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• pp.151-157
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• 2016

The present study was undertaken to clarify the changes in blood chemical values of indigenous Korean striped calves according to age. Blood samples were collected from 15 calves (8 females and 7 males) reared at the Gyeongsangbukdo Livestock Research Institute and the levels of various chemicals in serum were analyzed. The mean total protein, albumin and globulin concentration in calves increased from 2 weeks after birth, and the levels in females were higher than those in males at 8 weeks after birth. The mean glucose concentration increased significantly at 2 weeks after birth. The mean blood urea nitrogen concentration increased from 2 weeks after birth, whereas the mean creatinine concentration decreased significantly from 2 weeks after birth. The mean uric acid concentration increased gradually from 2 weeks after birth. The mean glutamic oxaloacetic transaminase and glutamic pyruvic transaminase concentration increased significantly from 2 weeks after birth. The mean total bilirubin concentration tended to decrease from 2 weeks after birth. The mean triglyceride, total cholesterol and high density lipoprotein cholesterol concentration increased significantly from 2 weeks after birth. In conclusion, the data obtained from this study may be valuable as a standard for interpreting results of biochemical analyses in indigenous Korean striped calves.

• Asian-Australasian Journal of Animal Sciences
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• 제15권11호
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• pp.1564-1567
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• 2002

Influence of dietary sesame meal on plasma glucose, non-esterified fatty acid (NEFA), triglyceride, total cholesterol, high-density lipoprotein (HDL)-cholesterol and urea concentrations in goats was examined. Goats were fed a control diet (50% timothy hay and 50% concentrates) (CD) or a sesame meal diet (50% timothy hay, 25% concentrates and 25% sesame meal) (SMD) during 12 days. Blood samples were taken after overnight fasting and afternoon every day. Body weight was not changed by feeding either CD or SMD. The concentrations of plasma triglyceride and urea were higher (p<0.05) in goats fed SMD than those fed CD. Plasma NEFA concentration was higher in plasma samples after overnight fasting. Plasma glucose concentration in plasma samples collected afternoon was higher than those after overnight fasting. Plasma total cholesterol concentration was significantly increased by feeding SMD but not by feeding CD, which was due to the remarkable increase of plasma HDL-cholesterol concentration. In conclusion, dietary sesame meal brought about an increase in plasma total cholesterol concentration accompanied with an increment in plasma HDL-cholesterol consentration in goats.

• 대한가정학회지
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• 제29권2호
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• pp.55-64
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• 1991

This study was designed to elucidate the effects of mugwort powder supplemented to high fat diets on blood components levels in rats. The levels of mugwort content in the experimental diets were divided into 12, 21, 28% and the fat levels in high fat diet was 30% of total caloie intake. Forty-nine male Sprague-Dawley rats weighing 72.5$\pm$0.3g were divided into group I(add mugwort during 8 weeks), group II(add during 4 weeks) andcontrol group. The results of this study were summarized as follows : 1. There were no difference in body weight gain and FER throughout eight weeks of experiment. The organ weights were somewhat higher in control group, but not significant. 2. The mugwort groups(I, II) were significantly higher than control group in RBC. This result showed that the mugwort affect the content of RBC. Author would like to conclude this result that the RBC content of experim-ental animal was affected by the iron in the mugwort. There were no difference among experimental groups in Hb, Hct. 3. It was noteworty that the concentration of serum glucose and triglyceride in the mugwort groups(I, II) was significantly lower than the control group. This result concluded that concentration of serum glucose and triglyceride which had become high by high fat diet were affected by the calcium or dietary fiber in the mugwort. There were no difference among experimental groups in albumin, total cho-lesterol, HDL-cholesterol.

• 한국식품영양학회지
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• 제15권4호
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• pp.289-294
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• 2002

본 연구에서 선발된 17종의 천연물을 Sprague-Dawleyra rat에 급여한 결과, 체중증가, 에너지 소비, fat pads 중량, 간의 triglyceride함량, atherogenic index 그리고 혈중 글루코오스의 함량 등이 감소하는 경향을 나타내었다. 특히 동아를 구강으로 섭취시킨 결과, 체중증가, 에너지 소비, fat pads 중량, 그리고 혈중 글루코오스의 함량 등이 감소하였으나, 간의 triglyceride 함량은 오디와 송엽의 열수 추출물보다 적게 감소하였다. 동아, 오디, 그리고 송엽을 혼합하여 사용한 결과, 각각의 원효를 사용할 경우보다 비만이 개선되는 것으로 나타났다.