• The Journal of Internal Korean Medicine
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• v.19 no.1
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• pp.491-504
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• 1998

Mainly side effects of antitumor chemotheraphy are fatigue, G-Ⅰ trouble(such as vomitting, nausea, diarrhea) and reduction of medullary function etc. Differentiated from syndromes in oriental medicine, above symptoms are recognized to 'Deficiency of both ki(vital energy) and blood'. And SDT(Sipjeondaebotang) has been widely used in 'Deficiency of both ki(vital energy) and blood'. Dr. Mun's SDTG(Sipjeondaebotanggamibang) consists of SDT plus several herb medicines-these have antitumor effect and reduce chemotherapheutic side effect. This experiment was undertaken to study the effects of SDTG on chemotherapheutic side effect and cytotoxicity. The results obtained in this study were as follows: Antitumor activities of the ethanol extract from SDTG(Sipjeondaebotanggamibang) and MMC(Mytomycin) on ascitis form of calcinoma in mice is a little improved. Especialy mean survival times of the group of SDTG(200mg/kg) and MMC(0.1mg/kg) is improved over 50%. When SDTG and MMC is administrated together, the weight of tumor is more decreased than MMC alone. The effect of the ethanol extract from SDTG and MMC on the lysosomal enzymes in Ehrich ascites carcinoma cell are more significantly improved than MMC alone. SDTG extract increases both NKcell conjugation and cyto-lysis against target cell. According to the above results it is recognized that SDTG increases the chemotherapheutic cytotoxicity of MMC and the activity of NKcell.

• Fashion & Textile Research Journal
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• v.13 no.5
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• pp.752-758
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• 2011

In this paper, experiments to develop working clothes and evaluated, including the current and material-improved working clothes in relation to physiological functionality measurement. Experiments were conducted on subjects after wearing working clothes in an climate chamber, and the thermo-physiological response, such as human body temperature, micro-climate within the clothes, blood pressure, heart rate were measured. In this manner, the physiological functionality of improved working clothes was compared with that of current working clothes and evaluated. The summary of obtained results is as follows: For physiological functionality evaluation through material-improved working clothes, P working clothes showed significantly lower rectal temperature than C working clothes. For mean skin temperature, P's skin temperature was significantly higher than C's in the second half of the experiment. P working clothes's temperature around the thighs in Micro climate was significantly lower than that of the C working clothes. Also, humidity within the clothes showed similar trends. During the exercise period, C working clothes showed higher blood pressure than P, but P showed higher heart rates than C. Also, the oxygen uptake amount was higher in C than P during the exercise period, it explains that the energy consumption amount of P working clothes was smaller than that of C working clothes. Of the subjective evaluation, for temperature sensation, workers wearing P working clothes felt cooler. For humidity, C working clothes showed more humidity. For comfort, P working clothes were better, and for sense of fatigue, workers felt less tired wearing P working clothes. From results above, we can see that physiological functionality improved in the material-improved working clothes in the working clothes for construction site workers. The improvement of working clothes through functionality improvements not only will provide personal pleasantness to constriction site workers, but will also generate efficiency and productivity improvements at construction sites. All in all, the continuous study of functionality improvements in working clothes taking into consideration the human body's physiological responses is required.

• Biomedical Science Letters
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• v.18 no.4
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• pp.384-390
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• 2012

Diabetes mellitus (DM) is considered to be a serious metabolic disease which may cause systemic complications. The present study was designed to clarify a difference on stress, physiological variables and their correlation between diabetic (DM group) and nondiabetic adults (control group). The levels of body weight, waist circumference, blood pressure, body mass index, body fat mass, total cholesterol (TcH), triglyceride (TG), aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma-glutamyltransferase (GGT), total bilirubin (TB), autonomic balance (AB), stress index (SI), fatigue index (FI), and heart rate (HR) were all significantly higher in the DM group than in the control group. However, the levels of autonomic activity (AA), stress resistance (SR), and electrocardiac stability (ES) were significantly lower in the DM group than in the control group. The percentages of persons with abnormal levels in the Tch, high density lipoprotein, low density lipoprotein, TG, AST, ALT and GGT were significantly greater in the DM group than in the control group. In the correlation of glucose and hemoglobin A1c (HBA1c) to stress indices, the DM group had a significant relationship with AB, SR, SI, FI, ES, and HR, whereas the control group had no significant relationship with these, excepting AB. These results suggest that DM was harmfully associated with body, biochemical and stress indices and that blood glucose and HBA1c levels must be exhaustively regulated.

• Korean Journal of Oriental Medicine
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• v.14 no.2
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• pp.101-106
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• 2008

Objective: The purpose of this study is to examine the characteristics and the improvement in the symptoms of the patients who showed improvement after the administration of Yeoldahanso-tang and Cheongpyesagan-tang. Methods: The patients whose Sasang Constitution were examined by an expert at six Oriental medical hospitals and three regional Oriental-medicine clinics, 89 showed a predetermined symptom improvement when Yeoldahanso-tang and Cheongpysagan-tang were administered to them from November 2007 to July 2008. The traits of the patients and the effects of their treatment were examined. Results and Conclusions: 1. There were about as many male patients as there were female patients, but 21.3% of the patients who were female and who were in their 40's showed the most improvement, which makes them the biggest category in this study. 2. The main syndromes in which the patients showed improvement were hemi-paralysis, vertigo, and headache, and the ordinary symptoms in which the patients showed improvement were diarrhea, fatigue, and dry mouth. 3. The average food intake of the patients was highest and their feces had intermediate hardness (semi-soft). 4. The amount of the patients' sweat was either high(38.2%) or appropriate(38.2%) and they showed a dislike of heat over coldness. 5. Among the diseases that the patients previously had, high blood pressure. The above results show that Yeoldahanso-tang and Cheongpyesagan-tang can be considered beneficial to females in their 40's and to stroke patients whose food intake is normal, whose sweat level is either copious or appropriate, who dislike heat and who are suffering from high blood pressure.

• Herbal Formula Science
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• v.18 no.2
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• pp.53-76
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• 2010

This report describes 173 formulas related to which are mainly used Paeoniae Radix in Dongeuibogam. The following conclusions were induced through investigations on the formulas that are used Paeoniae Radix as a main component. 1. We found the formulas in Dongeuibogam that Paeoniae Radix is used as a main ingredient in each prescriptions. 22 times(12.4%) of them are recorded in women's disease chapter, 20 times(11.3%) are in feces chapter, 14 times(7.9%) are in uterus, 12 times(6.8%) are in wind chapter, 10 times(5.6%) are in fatigue chapter, 9 times(5.1%) are in blood chapter, which are arranged in order of frequency. 2. Formulas that utilize Paeoniae Radix as the main ingredient are used in the treatment of women's disease, diarrhea, paralysis, yin and yang-deficiency syndrome. They are also used for treating 117 different types of diseases. 3. The dosage of Paeoniae Radix in formulas is from 1 don(nearly 3.75g) to 1 nyang 5 don (nearly 56.25g), however 1 don has been taken the most for clinical application. 4. Paeoniae Radix can make various effects with other ingredient, like fulfilling yin and blood, relaxing muscles and allaying pain. And this can be found in the formulas such as Samultang(四物湯), Jakyackgamchotang(芍藥甘草湯), Sambaektang(三白湯).

• Journal of Digital Convergence
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• v.14 no.6
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• pp.431-438
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• 2016

This study will be targeting 21-24 years old college students majoring in physical education. This study covers the effect of kinesiology taping and icing treatment on the recovery rate of blood lactate concentration, and cardiovascular function so that it can provide the basic data for improving physical performance. As a result of this study, Kinesio taping and icing aid the recovery rate of the maximum load of lactic acid recovery rate and 30 minutes after exercise heart rate after exercise, but increased, after 15 minutes, immediately after exercise heart rate, exercise lactate and heart rate, and 30 minutes after exercise lactate showed no difference. In conclusion, Kinesio taping and icing treatment, reduce pain and fatigue but it is not satisfactory. Further study, applying a more accurate and technical form of exercise programs needs to continuously research the effects of Kinesio taping and icing treatment

• Journal of Ginseng Research
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• v.44 no.4
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• pp.527-537
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• 2020

Panax ginseng, a medicinal plant, has been used as a blood-nourishing tonic for thousands of years in Asia, including Korea and China. P. ginseng exhibits adaptogen activity that maintains homeostasis by restoring general biological functions and non-specifically enhancing the body's resistance to external stress. Several P. ginseng effects have been reported. Korean Red Ginseng, in particular, has been reported in both basic and clinical studies to possess diverse effects such as enhanced immunity, fatigue relief, memory, blood circulation, and anti-oxidation. Moreover, it also protects against menopausal symptoms, cancer, cardiac diseases, and neurological disorders. The active components found in most Korean Red Ginseng varieties are known to include ginsenosides, polysaccharides, peptides, alkaloids, polyacetylene, and phenolic compounds. In this review, the identity and bioactivity of the non-saponin components of Korean Red Ginseng discovered to date are evaluated and the components are classified into polysaccharide and nitrogen compounds (protein, peptide, amino acid, nucleic acid, and alkaloid), as well as fat-soluble components such as polyacetylene, phenols, essential oils, and phytosterols. The distinct bioactivity of Korean Red Ginseng was found to originate from both saponin and non-saponin components rather than from only one or two specific components. Therefore, it is important to consider saponin and non-saponin elements together.

• Journal of the Korean Society of Food Science and Nutrition
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• v.43 no.12
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• pp.1937-1941
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• 2014

The effects of Tabebuia avellanedae (Taheebo) on exercise endurance capacity were investigated using mice in an adjustable-current water pool. Compared to the control group, a 1.8~2.0 fold increase in swimming time was observed in mice administered hot water extract (TAW) and 80% ethanol extract (TAE) of inner bark from T. avellanedae. Blood lactate level, an important fatigue relevance factor, was significantly lower in the TAW and TAE groups than in the control group. The total phenolic contents of TAW and TAE were $93.3{\pm}1.6$ and $115.7{\pm}1.5mgGAE/g$, respectively. The levels of flavonoids in the extracts were $77.3{\pm}1.3$ and $95.9{\pm}1.7mgCE/g$, respectively. Higher antioxidant activities of TAE were observed in each assay at the same concentration as compared to TAW. Correlation between antioxidant activities of TAE with total polyphenol contents was observed. These results suggest that extracts of Taheebo increase exercise endurance capacity by elevating antioxidative potentials.

• Journal of Sasang Constitutional Medicine
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• v.30 no.3
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• pp.48-61
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• 2018

Objectives The purpose of this study was to investigate the ordinary symptoms, special symptoms and Body Mass Index (BMI) according to Sasang constitution in female college students. Also, we aimed to analyze the factors affecting BMI. Methods Forty-four female college students participated in this study. Sasang Constitution was determined by Questionnaire for Sasang Constitution Classification (QSCC) II. BMI was measured and ordinary symptoms were acqired through the questionnaire. Special symptoms was determined by Fatigue Severity Index (FSS), Premenstrual Symptom Screening Tool (PSST), ROME III, Ocular Surface Disease Index (OSDI), respectively. For statistical analysis, t-test, analysis of variance and correlation test has been used. Results There existed significant differences in ordinary symptoms and special symptoms between sasang constitutions. Taeumin had higher urine frequency than soyangin, soeumin had higher gap of feces than taeumin. Taeumin had higher BMI and ROME III score than soyangin and soeumin. They showed significant differences in ordinary symptoms and special symptoms according to BMI. Overweight and obese group is higher in water intake than low and normal group. Low weight and normal group is higher in gap of feces than overweight and obese group. High score group in PSST and ROME III showed high BMI than low score group. We analyzed the factors that affect BMI. BMI are highly correlated with systolic and diastolic blood pressure. Also, FSS, PSST, ROME III and OSDI showed high correlation with each other. Conclusion Urine frequency and gap of feces are different among sasang constitutional types. The obese group and normal group showed significant differences in water intake, gap of feces, PSST and ROME III score. It is found that factors that affecting BMI are systolic and diastolic blood pressure. These results may lead to identifying the causes and factors of obesity in female college students related to Sasang constitution.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.6
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• pp.1742-1748
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• 2006

In order to establish the manifestational symptoms in men and women and highly frequent symptoms(HFS) of deficiency of Qi and blood(氣虛, 血虛), stagnation of Qi(氣滯), deficiency of Yin(陰虛), deficiency of Yang(陽虛), and, 546 questionaires were analyzed through Cronbach alpha value and Pearson's correlative efficient. Symptomatic differences of male and female specimens were as follows. HFS of Qi deficiency were similar in terms of inactivity like mental and physical fatigue, enervation in men and women. In blood deficiency, dizziness and light sleep were common in men and women, but mucosal symptoms of conjunctiva, lip, nail bed were more frequent in women than men. Emotional explosion was common in Qi stagnation, then women had more motivation-related symptoms than men. Inner heat was frequently arisen in Yin deficiency in both, and the heat was expressed more common in exterior and upper part in women but in interior abdominal part in men. In Yang deficiency, main symptoms of men were feeling coldness in peripheral, but Qi deficiency symptoms were more common in women former than coldness.