• Title/Summary/Keyword: block division

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Poly(benzyl-L-histidine)-b-Poly(ethylene glycol) Micelle Engineered for Tumor Acidic pH-Targeting, in vitro Evaluation

  • Lee, Eun-Seong;Youn, Yu-Seok
    • Bulletin of the Korean Chemical Society
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    • v.29 no.8
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    • pp.1539-1544
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    • 2008
  • A polymeric micelle, based on the poly(benzyl-L-histidine)-b-poly(ethylene glycol) (polyBz-His-b-PEG) diblock copolymer, was designed as a tumor-specific targeting carrier. The micelles (particle size: 67-80 nm, critical micelle concentration (CMC); 2-3 $\mu$g/mL) were formed from the diafilteration method at pH 7.4, as a result of self-assembly of the polyBz-His block at the core and PEG block on the shell. Removing benzyl (Bz) group from polyBz-His block provided pH-sensitivity of the micellar core; the micelles were physically destabilized in the pH range of pH 7.4-5.5, depending on the content of the His group free from Bz group. The ionization of His group at a slightly acidic pH promoted the deformation of the interior core. These pHdependent physical changes of the micelles provide the mechanism for pH-triggering anticancer drug (e.g., doxorubicin: DOX) release from the micelle in response to the tumor’s extracellular pH range (pH 7.2-6.5).

Models for Determining the Size of Import Container Block in Automated Container Terminals (자동화 컨테이너 터미널에서 수입 컨테이너 장치 블록 크기 결정을 위한 모형)

  • Kim, Ki-Young
    • Journal of Navigation and Port Research
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    • v.31 no.8
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    • pp.705-710
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    • 2007
  • The productivity of automated container terminals is significantly affected by not only the speed related performances of automated transfer cranes(ATCs) but also the sizes of container blocks. In this paper, it is discussed how to determine the size of import container blocks considering both the container handling times of an ATC and their storage space. Firstly, evaluation models are suggested for the container handling times of an ATC in a typical import container blocks. Secondly, three mathematical formulations are suggested to determine the size of import container blocks. Numerical experiments for the suggested models to determine the size of import container block are provided.

Partitioned Block Frequency Domain Adaptive Filtering Algorithm for Nonlinear Acoustic Echo Cancellation (비선형 음향 반향 제거를 위한 파티션 블록 주파수 영역 적응 필터링 알고리즘)

  • Lee, Keunsang;Ji, Youna;Park, Youngcheol
    • The Journal of the Acoustical Society of Korea
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    • v.34 no.3
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    • pp.177-183
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    • 2015
  • This paper proposes a robust nonlinear acoustic echo canceller (NAEC) which is effective for modeling the nonlinearity of a speaker module and the long acoustic echo path within a speech communication environment. The proposed NAEC utilizes a sigmoid pre-processor for modeling the speaker nonlinearity and a partitioned block frequnecy-domain adaptive filter for identifying the acoustic echo path with small delay. Simulation results confirmed that the proposed algorithm achieves excellent performance with much lower computational complexity than the previous NAEC.

Secure Block Cipher Algorithm for DC and LC (DC와 LC에 안전한 SPN 구조 암호 알고리즘)

  • Choe, Eun-Hwa;Seo, Chang-Ho;Seong, Su-Hak;Ryu, Hui-Su;Jeon, Gil-Su
    • The KIPS Transactions:PartC
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    • v.9C no.4
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    • pp.445-452
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    • 2002
  • In this paper, we suggest the design of 128bit block cipher which is provable security based on mathematics theory. We have derived the 16$\times$16 matrix(i.e.,linear transformation) which is numerous active S-box, and we proved for DC and LC which prove method about security of SPN structure cipher algorithm. Also, the minimum number of active S-box, the maximum differential probabilities and the maximum linear probabilities in round function of 128bit block cipher algorithm which has an effect to DC and LC are derived.

Reinforcement design for the anchorage of externally prestressed bridges with "tensile stress region"

  • Liu, C.;Xu, D.;Jung, B.;Morgenthal, G.
    • Computers and Concrete
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    • v.11 no.5
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    • pp.383-397
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    • 2013
  • Two-dimensional tensile stresses are occurring at the back of the anchorage of the tendons of prestressed concrete bridges. A new method named "tensile stress region" for the design of the reinforcement is presented in this paper. The basic idea of this approach is the division of an anchor block into several slices, which are described by the tensile stress region. The orthogonal reinforcing wire mesh can be designed in each slice to resist the tensile stresses. Additionally the sum of the depth of every slice defined by the tensile stress region is used to control the required length of the longitudinal reinforcement bars. An example for the reinforcement design of an anchorage block of an external prestressed concrete bridge is analyzed by means of the new presented method and a finite element model is established to compare the results. Furthermore the influence of the transverse and vertical prestressing on the ordinary reinforcement design is taken into account. The results show that the amount of reinforcement bars at the anchorage block is influenced by the layout of the transverse and the vertical prestressing tendons. Using the "tensile stress region" method, the ordinary reinforcement bars can be designed more precisely compared to the design codes, and arranged according to the stress state in every slice.

The Simulation System for Scheduling Validation of the Panel Block Shop (판넬 블록공정 모델에 대한 일정검증 시뮬레이션 시스템)

  • Lee, Phi-Lippe;Oh, Dae-Kyun;Lee, Kwang-Kook;Shin, Jong-Gye
    • Journal of the Society of Naval Architects of Korea
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    • v.46 no.6
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    • pp.641-649
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    • 2009
  • There were many simulation models that made for validation of industrial environment and estimate of efficiency to be constructed. And there will be more simulation models made for same reason, too. Already, there have been a lot of simulation models in industry field and scholar labs. To reuse these simulation models, it is necessary to find common properties and make the high abstract simulation model. Based on this idea, this study shows to define the high abstract simulation model to be able to specialize in need and to make the software framework for connecting the specific simulation model to the abstract model. And it is held up as the example that applying the simulation framework to the Ship Panel Block shop simulation model.

Implementation of Low Complexity FFT, ADC and DAC Blocks of an OFDM Transmitter Receiver Using Verilog

  • Joshi, Alok;Gupta, Dewansh Aditya;Jaipuriyar, Pravriti
    • Journal of Information Processing Systems
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    • v.15 no.3
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    • pp.670-681
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    • 2019
  • Orthogonal frequency division multiplexing (OFDM) is a system which is used to encode data using multiple carriers instead of the traditional single carrier system. This method improves the spectral efficiency (optimum use of bandwidth). It also lessens the effect of fading and intersymbol interference (ISI). In 1995, digital audio broadcast (DAB) adopted OFDM as the first standard using OFDM. Later in 1997, it was adopted for digital video broadcast (DVB). Currently, it has been adopted for WiMAX and LTE standards. In this project, a Verilog design is employed to implement an OFDM transmitter (DAC block) and receiver (FFT and ADC block). Generally, OFDM uses FFT and IFFT for modulation and demodulation. In this paper, 16-point FFT decimation-in-frequency (DIF) with the radix-2 algorithm and direct summation method have been analyzed. ADC and DAC in OFDM are used for conversion of the signal from analog to digital or vice-versa has also been analyzed. All the designs are simulated using Verilog on ModelSim simulator. The result generated from the FFT block after Verilog simulation has also been verified with MATLAB.

A Differential SFBC-OFDM for a DMB System with Multiple Antennas

  • Woo, Kyung-Soo;Lee, Kyu-In;Paik, Jong-Ho;Park, Kyung-Won;Yang, Won-Young;Cho, Yong-Soo
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.32 no.2A
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    • pp.195-202
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    • 2007
  • A differential space-frequency block code - orthogonal frequency division multiplexing (SFBC-OFDM) scheme as a multiple-input multiple-output (MIMO) transmission technique for next-generation digital multimedia broadcasting (DMB) is proposed in this paper. A linear decoding method for differential SFBC, which performs comparably to the ML decoding method, is derived for the cases of two or four transmit antennas. A simple table lookup method is proposed to improve the efficiency of the encoding/decoding process of DSFBC for the case of non-constant modulus constellations. A DMB MIMO channel model, developed by extending the 3GPP MIMO model to fit DMB environments, is used to compare BER performances of differential space block code schemes for various channel environments. Simulation results show that the differential SFBC-16QAM scheme using either four transmit antennas with one receive antenna or two transmit antennas with two receive antennas achieves a performance gain of 12dB than that of the conventional DQPSK scheme, even with a data rate twice faster.

Preparation and Characterization of PEG/PLA Multiblock and Triblock Copolymer

  • Zhao, Hesong;Liu, Zhun;Park, Sang-Hyuk;Kim, Sang-Ho;Kim, Jung-Hyun;Piao, Longhai
    • Bulletin of the Korean Chemical Society
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    • v.33 no.5
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    • pp.1638-1642
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    • 2012
  • A series of poly (lactic acid) (PLA) and poly (ethylene glycol) (PEG) tri and multiblock copolymers with relatively high molecular weights were synthesized through the coupling reaction between the bis(acyl chloride) of carboxylated PLA and mono or dihydroxy PEG. The coupling reaction and the copolymer structures were monitored by nuclear magnetic resonance (NMR), Fourier transform infrared spectroscopy (FTIR) and gel permeation chromatography (GPC). The melting temperature (Tm) of PEG blocks decreased with the presence of PLA sequences attaching to PEG blocks. The CMC values were determined to be 10-145 mg/L depending on the length of PLA and PEG blocks and the structure of the block copolymers.

Iterative Channel Estimation for Higher Order Modulated STBC-OFDM Systems with Reduced Complexity

  • Basturk, Ilhan;Ozbek, Berna
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.10 no.6
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    • pp.2446-2462
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    • 2016
  • In this paper, a frequency domain Expectation-Maximization (EM)-based channel estimation algorithm for Space Time Block Coded-Orthogonal Frequency Division Multiplexing (STBC-OFDM) systems is investigated to support higher data rate applications in wireless communications. The computational complexity of the frequency domain EM-based channel estimation is increased when higher order constellations are used because of the ascending size of the search set space. Thus, a search set reduction algorithm is proposed to decrease the complexity without sacrificing the system performance. The performance results of the proposed algorithm is obtained in terms of Bit Error Rate (BER) and Mean Square Error (MSE) for 16QAM and 64QAM modulation schemes.