• Nuclear Engineering and Technology
• /
• v.54 no.10
• /
• pp.3833-3840
• /
• 2022

A method for calibrating the energy scale and detection efficiency of stilbene scintillators is presented herein. This method can be used to quantitatively analyze the Compton continuum of gamma-ray spectra obtained using such scintillators. First, channel-energy calibration was conducted by fitting a semi-empirical equation for the Compton continuum to the acquired energy spectrum and a new method to evaluate the intrinsic detection efficiency, called intrinsic Compton efficiency, of stilbene scintillators was proposed. The validity of this method was verified by changing experimental conditions such as the number of sources being measured simultaneously and the detector-source distance. According to the energy calibration, the standard error for the estimated Compton edge position was ±1.56 keV. The comparison of the intrinsic Compton efficiencies calculated from the single- and two-source spectra showed that the mean absolute difference and the mean absolute percentage difference are 0.031 %p and 0.557%, respectively, demonstrating reasonable accuracy of this method. The feasibility of the method was confirmed for an energy range of 0.5-1.5 MeV, showing that stilbene scintillators can be used to quantitatively analyze gamma rays in mixed-radiation fields.

• Journal of Korean Society of Rural Planning
• /
• v.19 no.4
• /
• pp.125-135
• /
• 2013

Analysis and evaluation of uncertainty is adopting the advanced methodology among the methods for greenhouse gas emission assessment that was defined in GPS2000 (Good practice guideline 2000) and GPG-LULUCF (GPG Land Use, Land-Use Change and Forestry). In 2006 IPCC guideline, two approaches are suggested to explain the uncertainty for each section with a national net emission and a prediction value on uncertainty as follows; 1) Spread sheet calculation based on the error propagation algorithm that was simplified with some assumptions, and 2) Monte carlo simulation that can be utilized in general purposes. There are few researches on the agricultural field including greenhouse gas emission that is generated from livestock and cultivation lands due to lack of information for statistic data, emission coefficient, and complicated emission formula. The main objective of this study is to suggest an evaluation method for the uncertainty of greenhouse gas emission in agricultural field by means of intercomparison of the prediction value on uncertainties which were estimated by spread sheet calculation and monte carlo simulation. A statistic analysis for probability density function for uncertainty of emission rate was carried out by targeting livestock intestinal fermentation, excrements treatment, and direct/indirect emission from agricultural lands and rice cultivation. It was suggested to minimize uncertainty by means of extraction of emission coefficient according to each targeting section.

• Journal of Bio-Environment Control
• /
• v.24 no.3
• /
• pp.147-152
• /
• 2015

In order to develop the cooling load estimation method in the greenhouse, the cooling load calculation formula based on the heat balance method was constructed and verified by the actual cooling load measured in the fog cooling greenhouse. To examine the ventilation heat transfer in the cooling load calculation formula, we measured ventilation rates in the experimental greenhouse which a cooling system was not operated. The ventilation heat transfer by a heat balance method showed a relatively good agreement. Evaporation efficiencies of the two-fluid fogging system were a range of 0.3 to 0.94, average 0.67, and it showed that they increased as the ventilation rate increased. We measured thermal environments in a fog cooling greenhouse, and calculated cooling load by heat balance equation. Also we calculated evaporative cooling energy by measuring the sprayed amount in the fogging system. And by comparing those two results, we could verify that the calculated and the measured cooling load showed a relatively similar trend. When the cooling load was low, the measured value was slightly larger than calculated, when the cooling load was high, it has been found to be smaller than calculated. In designing the greenhouse cooling system, the capacity of cooling equipment is determined by the maximum cooling load. We have to consider the safety factor when installed capacity is estimated, so a cooling load calculation method presented in this study could be applied to the greenhouse environmental design.

• Agribusiness and Information Management
• /
• v.6 no.2
• /
• pp.40-48
• /
• 2014

As basic research to develop HEV and EV agricultural field machinery, the present study analyzes the technical trend of electric agricultural field machinery through product analysis, paper analysis, and patent analysis concerning HEV and EV in the automobile, construction machinery, and agricultural machinery sectors. For product analysis, the homepages of companies in these sectors were consulted to analyze the number of products of each company. For paper analysis, key words related to HEV and EV were selected, a search formula was drawn up, and articles search sites were consulted. And for patent analysis too, key words were selected and then a search formula was drawn up to examine published patent applications or registered patent applications, and trends were analyzed by structure, country, and year. The number of HEV and EV products were 17 in the automobile area, 8 in construction machinery, and 4 in agricultural machinery. Notably, in the agricultural machinery area, all HEV and EV products were from advanced companies overseas. In terms of papers, papers published in the past 5 years were searched and 33,195 papers were from the automobile area, 3,806 were from construction machinery, and 2,687, the fewest papers, were from the agricultural machinery area. A search of patents in the electric drive technology area in Korea, USA, and Japan, and Europe showed 1,927 valid patents, with 1,120 in Japan, 497 in USA, 193 in Korea, and 117 in Europe. Analysis of the trend of research on electric agricultural field machinery by product, paper, and patent shows the development of HEV and EV technology in Korea is insufficient compared to USA, Japan, and Europe, which means rapid technological development is needed.

• Herbal Formula Science
• /
• v.28 no.4
• /
• pp.385-406
• /
• 2020

Objectives : To study the use of Cinnamomum cassia among the 394 prescriptions listed in Donguibogam Methods : After selecting a total of 394 prescriptions, 284 prescriptions with Cinnamon Cassia as the protagonist were analyzed and summarized in the table. In particular, the investigation was conducted by comparing the Cinnamomi Ramulus and Cinnamomi Cortex. Results : The Cinnamomum cassia is used in 52 fields of treatment such as common cold & flu diseases, abscess and stroke, etc. Prescriptions containing Cinnamomi Ramulus were most commonly used for cold disease. And prescriptions containing Cinnamomi Cortex were most commonly used for wind diseases. Prescriptions that utilize Cinnamomum cassia are used in the treatment of feeling of cold, numbness, low back pain, cough and so on. Prescriptions containing Cinnamomi Ramulus mainly treat cold disease. And prescriptions containing Cinnamomi Cortex treat mainly abdominal pain and diarrhea. 14 prescriptions of the same name are included with Cinnamomum cassia. The other unclassified Cinnamomum cassia is considered suitable for use with Cinnamomi Cortex. Cinnamomum cassia is only used as a raw material. Conclusions : According to the classification of Cinnamomum cassia, further study of prescription utilization is needed.

• Herbal Formula Science
• /
• v.28 no.4
• /
• pp.327-337
• /
• 2020

Objective : Citri Unshius Pericarpium is the dried peel of mature fruit of Citrus unshiu Markovich and has been used to treat indigestion, vomiting, and removal of phlegm. This study investigated the hepatoprotective and antioxidant effect of CEE (Ethanol extract of Citri Unshius Pericarpium) in cadmium (CdCl₂)-treated HepG2 cells. Methods : Component analysis of Citri Unshius Pericarpium was analyzed by UPLC with C₁₈ column. Cell viability was determined by MTT assay. The enzyme activity of superoxide dismutase (SOD) and the level of reactive oxygen species (ROS) and reduced glutathione (GSH) were analyzed using commercially available kits. Results : Cadmium caused severe HepG2 cell death. Cadmium also increased ROS production, consistent with depletion of GSH and inhibition of the SOD enzyme. However, CEE treatment reduced cell death and relieved oxidative stress caused by cadmium toxicity. CEE lowered ROS levels and improved depletion of GSH levels. CEE also enhanced the enzymatic activity of SOD. In component analysis, hesperidin was the most abundant of the five marker compounds (Narigenin, Narigin, Narirutin, Hesperidin and Hesperidin), which assumes that hesperidin partially contributed to the antioxidant activity of CEE. Conclusion : These results suggested that CEE could be a potential substance to solve heavy metal-related health problems. In particular, inhibition of oxidative stress by CEE can be a way to treat liver damage caused by cadmium.

• Herbal Formula Science
• /
• v.28 no.4
• /
• pp.365-384
• /
• 2020

Objectives : This report describes 241 prescriptions related to the use of Gardenia Fructus blended prescriptions from Dongeuibogam. Methods : The following conclusions were reached through investigations on the prescriptions that use Gardeniae Fructus. Results : The Gardeniae Fructus is used in 49 fields of treatment such as urinary diseases, jaundice and furuncle, etc. Prescriptions that utilize Gardeniae Fructus are used in the treatment of fever, eye disease, hemorrhage, skin disease, ear disease, internal disease and so on. In the view of the causative agent of a disease, the prescriptions which are compounded with Gardeniae Fructus are related to endogenous agents such as jaundice, seven emotion, alcohol, exogenous agents such as cold, wind, heat and non-endo-exopathogenic factors like disease due to external factor, injury. The dosage of Gardeniae Fructus is 1pun(about 0.375) to 5don 5pun(about 21g), however 5pun(about 1.87g)~1don(about 3.75g) has been taken the most for clinical application. Conclusions : Hwangryunhaedok-tang is the most base prescriptions which use the Gardenia Fructus. Gardeniae Fructus is mainly used as a raw material.

• Herbal Formula Science
• /
• v.20 no.2
• /
• pp.55-63
• /
• 2012

Objectives : This study was conducted to investigate the safety of Bangpungtongsung-san in rats. Methods : The safety of this prescription on acute toxicity was evaluated by single dose toxicity study. Rats were orally administrated in a single dose of 0 and 2,000 mg/kg(limited dose) Bangpungtongsung-san. There were 7 rats in each groups. All animals were sacrificed after 14 days of treatment. After single administration, mortality, clinical signs, and body weight changes were observed for 14 days. Three parameters(autopsy finding, clinical chemistry, and hematology) were tested on the last day. Results : In this study with rats, Bangpungtongsung-san treatment did not show any acute toxicity. No mortality was noted for 14 days of treatment. There were no adverse effects on clinical signs, body weight changes, and autopsy finding at all treatment groups. The clinical chemistry parameters attesting to liver and kidney functions as well as the hematological parameters were within the normal ranges. Conclusions : It is considered that $LD_{50}$ of Bangpungtongsung-san is over 2,000 mg/kg in oral administration by rats. This finding of the safety of Bangpungtongsung-san is expected to strengthen the position of this prescription as nontoxic medicine.

• Journal of TMJ Balancing Medicine
• /
• v.3 no.1
• /
• pp.15-22
• /
• 2013

Objectives and Methods: This study was conducted to investigate the formula of ONGABO to composed of Ginseng Radix (Red Ginseng), Angelica Gigantis Radix, Schisandrae Fructus, Cuscuta Semen, Curcumae Tuber with the method to observe the cell viability of HepG2 in the basic principle of oriental medicine formula study, Sovereign, Minister, Assistant and Courier principle (君臣佐使論). Results: Ginseng Radix (Red Ginseng) and Schisandrae Fructus were having a cell protection effect in HepG2 significantly. Angelica gigantis radix was decreased the cell viability of HepG2 significantly, and there were no effects for Cuscuta Semen and Curcumae Tuber to the cell viability of HepG2. Conclusions: As the above results, in the Sovereign, Minister, Assistant and Courier principle (君臣佐使論), Ginseng Radix (Red Ginseng) corresponds to sovereign medicinal having cell protect effects, angelica gigantis radix corresponds to minister medicinal having cell killing effects, Schisandrae Fructus corresponds to assistant medicinal to help red ginseng having cell protect effects. Cuscuta Semen and Curcumae Tuber correspond to courier medicinal having no effect in cell viability in HepG2. We hope the advanced research on sovereign, minister, assistant and courier principle will be proceed in the tomorrow.

• Journal of Animal Reproduction and Biotechnology
• /
• v.37 no.1
• /
• pp.27-33
• /
• 2022

Functional dyspepsia (FD) is a gastrointestinal disorder with diverse symptoms but no structural or organic manifestations. Benachio-F^® (herein named 'BF-1') is an over-the-counter liquid digestive formulated with multiple herbal extracts, which has been reported to improve symptoms of FD. A total two experiments were conducted. First, we examined whether BF-1 can modulate the progression of FD through two experimental rat models. A total of three doses (0.3x, 1x, 3x of the human equivalent dose) were used. In the gastric emptying model, both 1x (standard) or 3x (3-fold-concentrated) BF-1 enhanced gastric emptying was compared with that of vehicle-treated animals. In a feeding inhibition model induced by acute restraint stress, treatment with 1x or 3x BF-1 led to a similar degree of restoration in food intake that was comparable to that of acotiamide-treated animals. Among the constituents of BF, fennel is known for its choleretic effect. Thus, we next investigated whether a novel BF-based formula (named 'BF-2') that contains an increased amount of fennel extract (3.5-fold over BF-1), has greater potency in increasing bile flow. BF-2 showed a superior choleretic effect compared to BF-1. Furthermore, the postprandial concentration of serum secretin was higher in animals pretreated with BF-2 than in those pretreated with BF-1, suggesting that the increased choleretic effect of BF-2 is related to secretin production. Our results demonstrate that BF-1 can modulate the pathophysiological mechanisms of FD by exerting prokinetic and stress-relieving effects, and that BF-2 has a better choleretic effect than BF-1.