• Title/Summary/Keyword: beta test

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Factors related to empowerment of paramedic students who experienced clinical practice (임상실습을 경험한 응급구조(학)과 학생의 임파워먼트 관련 요인)

  • Song, Seo-Yeong;Han, Mi-Ah
    • The Korean Journal of Emergency Medical Services
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    • v.20 no.1
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    • pp.17-30
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    • 2016
  • Purpose: This study investigated factors related to empowerment of paramedic students. Methods: A total of 208 students in the department of emergency medical services who experienced clinical practice at 5 universities were selected by convenience sampling methods. Differences in empowerment by general and major-related characteristics were evaluated using a t-test and analysis of variance. The association between satisfaction with clinical practice and empowerment was tested using correlation coefficients. Multiple linear regression analysis was performed to investigate the factors associated with empowerment. Results: The levels of overall satisfaction with clinical practice and empowerment were 107.48 and 99.46, respectively. In simple analysis, empowerment level was associated with general characteristics, major-related characteristics, characteristics of clinical practice, and satisfaction with clinical practice. Empowerment level was significantly higher in older subjects (${\beta}=5.282$, p = .023), subjects with very good (${\beta}=8.487$, p = .002) or fair (${\beta}=4.879$, p = .010) subjective health status, and high subjective school record (${\beta}=5.837$, p = .008) in multiple linear regression analysis. Satisfaction with clinical practice was positively associated with empowerment (${\beta}=0.250$, p < .001). Conclusion: Empowerment was associated with major-related factors and satisfaction with clinical practice. Increased satisfaction with clinical practice could positively influence empowerment for paramedic students.

Immuno enhancing and chemopreventing agent from mushroom mycelial culture (버섯균사체 배양물로부터 면역증진 기능성 소재 개발)

  • Kim, Jeong-Ok
    • Proceedings of the Korean Society of Postharvest Science and Technology of Agricultural Products Conference
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    • 2007.11a
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    • pp.27-31
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    • 2007
  • This study relates to low and medium molecular weight isoflavone-${\beta}$-D-glucan produced by submerged liquid culture of Agaricus blazei, a method of producing the isoflavone-B-D-glucan using autolysis enzyme of Agaricus blazei mycelia, and use of the isoflavone-B-D-glucan for anti-cancer and immunoenhancing effect. In acordance with one aspect of the present study, it deals with a method of producing isoflavone-${\beta}$-D-glucan, which comprises the followings; 1) culturing and separating mushroom mycelia, 2) producing low-medium molecular weight isoflavone-${\beta}$-D-glucan from high molecular weight one. The cytotoxicity on human cnacer cell line (Caco-2, MCF-7), the expression of Cyclin D, Bcl-2, Bax protein, p21 protein, p53 protein in MCF-7 cells assessed by SDS-PAGE and immunoblotting, and other immuno related factors such as TNF-${\alpha}$ and IL-1B activities were examined. Structural identification of isoflavone-${\beta}$-D-glucan which showed cytotoxicity against cancer cell and immunoenhancing effects was carried by separation with DEAE-cellulose column chromatography, TLC, HPLC, IR, NMR. Clinical test for the cancer patients (n=119) for 6 month was carried out, and immunoenhancing factors (NK. cell number, ratio of T4/T8) were checked. We concluded the identified isoflavone-${\beta}$-D-glucan has immuno enhancing effects and could be useful for cancer chemoprevention.

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Immunomodulatory Effects of Zingiber officinale in Cyclophosphamide-induced Immunosuppress Mice (Cyclophosphamide로 유발된 면역억제 마우스에서 생강의 면역 억제 효과)

  • Koo, Sung-Wook;Lim, Mee-Kyung;Lee, Keun-Woo
    • Journal of Veterinary Clinics
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    • v.32 no.1
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    • pp.56-61
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    • 2015
  • The object of this study was to find out the immunomodulatory effects of Ginger Aqueous extracts, as compared with that of ${\beta}$-glucan well-known an immune modulator, on the cyclophosphamide (CPA) induced immunosuppress mice. To induce immunosuppress, 150 and 110 mg/kg of CPA were dissolved in saline and injected intraperitoneally at 3 or 1 day before start of test article administration, respectively. ${\beta}$-glucan or gingers (125, 250, 500 mg/kg) were dosed, 4 times at 12-hr intervals starting 24hrs after last CPA-treatment. Distilled water was used as a vehicle and each groups were used 10 mice. As results of twice intraperitoneal CPA treatment, decreases in the body weight and gain, weight of thymus, spleen. However these CPA-induced immunosuppress changes were inhibited by treatment of three different dosages of ginger or ${\beta}$-glucan as compared with CPA control. Similar favorable inhibitory activities on weight and histopathological change of spleen and thymus induced CPA treatment were detected between ${\beta}$-glucan and ginger 250 mg/kg treated groups.

Isolation and characteristics of serotype F staphylococcal phage singly converting staphylokinase (Staphylokinase 단독변환 혈청형 F 포도구균 phage의 분리 및 특성)

  • Park, Cheong-kyu;Seo, Mi-sook
    • Korean Journal of Veterinary Research
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    • v.40 no.1
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    • pp.49-55
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    • 2000
  • Lysogenic conversion of Staphylococcus aureus to loss of ${\beta}-hemolysin$ production by serological group F phages is always associated with gain in staphylokinase production. In this study, the new phages belonging to serotype F were detected during the course of isolation of phages from Staph aureus of bovine origin and some characteristics of the new phages isolated were investigated. The new phages, ${\phi}470$ and ${\phi}499$, isolated from Staph aureus producing ${\beta}-hemolysin$ and staphylokinase(${\beta}^+\;K^+$) were found to convert ${\beta}^+\;K^+$ strain to ${\beta}^+K\;^+$, Staph aureus strains lysogenized by this serotype F single-converting phage ${\phi}470$ or ${\phi}499$ could be again lysogenized with serotype F double-converting phage ${\phi}506$. The frequency of lysogenization of indicator strains by serotype F single-converting phage was 100%, whereas the frequency for serotype F double-converting phage ${\phi}506$ varied from 4.2% to 97.6% according to the indicator strains. The indicator strain lysogenized with phage ${\phi}470$ was resistant to phage ${\phi}499$, and vice versa, but not to phage ${\phi}506$. Therefore, phage ${\phi}470$ and ${\phi}499$ were shown to be identical by immunity test.

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Effect of aging treatment on the microstructures and mechanical properties of 6N01 Aluminium alloy (6N01 Al 합금의 미세조직 및 기계적 성질에 미치는 시효처리의 영향)

  • Kang, Min-Cheol;Koo, Hung-Suh;Yun, In-Taeg;Kang, Chung-Yun;Kim, In-Bae
    • Journal of the Korean Society for Heat Treatment
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    • v.11 no.4
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    • pp.268-273
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    • 1998
  • Effect of aging treatment on the microstructures and mechanical properties of 6N01 Aluminium alloy was investigated by differential scanning calorimetry, transmission electron microscopy, microhardness measurement and tensile test. It was found that the precipitation sequence of 6N01 Aluminium alloy was GP zone ${\rightarrow}$ metastable hexagonal $Mg_2S_i({\beta}^{\prime})$,${\rightarrow}$ equilibrium fcc $Mg_2S_i({\beta})$, and the precipitates at peak aged condition were GP zones and ${\beta}^{\prime}$ phase. Microhardness changes during over aged condition showed very small decrease upon increased aging time. This result was attributed to the very slow transformation rate of ${\beta}^{\prime}$ to ${\beta}$. Maximum hardness(116 Hv) and tensile strength(312.6MPa) with 22.3% elongation were obtained from the specimen aged at $180^{\circ}C$ for 15hrs.

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The Effects of Emotional Labor and Job Involvement on Turnover Intention of Nurses in Long-term Care Hospitals (요양병원 간호사의 감정노동과 직무몰입이 이직의도에 미치는 영향)

  • Kang, Su-Jeong;Kwon, Suhye
    • Korean Journal of Occupational Health Nursing
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    • v.24 no.4
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    • pp.290-301
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    • 2015
  • Purpose: The purpose of this study was to identify the influencing factors on turnover intention of nurses in long-term care hospitals. Methods: Data were collected from 210 nurses in 11 long-term care hospitals in B city. Data were analyzed using descriptive statistics, t-test, ANOVA, Pearson's correlation coefficient, and Stepwise multiple regression. Results: Turnover intention was significantly correlated with emotional labor(r=.35, p<.001) and job involvement (r=-.38, p<.001). In a multiple regression, emotional labor (${\beta}=.31$, p<.001), age (${\beta}=-.27$, p<.001), job satisfaction (${\beta}=.24$, p<.001), job involvement (${\beta}=-.23$, p<.001), and number of patients assigned(${\beta}=.14$, p=.009) were associated with turnover intention. These factors attributed to 41.2% of the total variance in turnover intention. Conclusion: Considering the results of this study, proactive educational and/or human resource management interventions need to be developed especially for those younger nurses in order to reduce emotional labor as well as to promote job satisfaction and job involvement of nurses in long-term care hospitals.

버섯균사체 배양물로부터 면역증진 기능성 소재 개발

  • Kim, Jeong-Ok
    • Food preservation and processing industry
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    • v.6 no.2
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    • pp.11-13
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    • 2007
  • This study relates to low and medium molecular weight isoflavone-${\beta}$-D-glucan produced by submerged liquid culture of Agaricus blazei, a method of producing the isoflavone-B-D-glucan using autolysis enzyme of Agaricus blazei mycelia, and use of the isoflavone-B-D-glucan for anti-cancer and immunoenhancing effect. In acordance with one aspect of the present study, it deals with a method of producing isoflavone-${\beta}$-D-glucan, which comprises the followings; 1) culturing and separating mushroom mycelia, 2) producing low-medium molecular weight isoflavone-${\beta}$-D-glucan from high molecular weight one. The cytotoxicity on human cnacer cell line (Caco-2, MCF-7), the expression of Cyclin D, Bcl-2, Bax protein, p21 protein, p53 protein in MCF-7 cells assessed by SDS-PAGE and immunoblotting, and other immuno related factor such as TNF-a and IL-1B activities were examined. Structural identification of isoflavone-${\beta}$-D-glucan which shoed cytotoxicity against cancer cell and immunoenhancing effects was carried by separation with DEAE-cellulose column chromatography, TLC, HPLC, IR, NMR, Clinical test for the cancer patients (n=119) for 6 month was carried out, and immunoenhancing factors(NK cell number, ratio of T4/T8) were checked. We concluded the identified isoflavone-${\beta}$-D-glucan has immuno enhancing effects and could be useful for cancer chemoprevention.

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Comparison of Factors influencing Depression between Non-Multicultural and Multicultural Middle School Students (비다문화 중학생과 다문화 중학생의 우울 관련 요인 비교)

  • Jang, Hyungsoon;Park, Hyunju
    • Journal of the Korean Society of School Health
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    • v.32 no.1
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    • pp.10-19
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    • 2019
  • Purpose: The purpose of this study was to compare the factors related to depression between non-multicultural and multicultural middle school students. Methods: In this study, data were collected using structured questionnaires targeting students of 9 middle schools in G Province, Korea. Finally, the data of 304 students were analyzed by descriptive statistics, t-test, ANOVA, Pearson's correlation, and multiple regression analyses using SPSS 24.0. Results: The multicultural students showed a higher depression score ($47.14{\pm}8.33$) than the counterpart ($44.22{\pm}8.11$) (p<.001). The results of the multiple regression analysis revealed that academic stress (${\beta}=.33$, p<.001), peer attachment (${\beta}=-.13$, p<.02), and body image (${\beta}=.25$, p<.001) were the influencing factors on depression in non-multicultural students. However, in multicultural students, depression was related to peer attachment (${\beta}=-.16$, p=.03) and self-esteem (${\beta}=-.42$, p<.001). Conclusion: To prevent and manage depression in non-multicultural middle school students, it is essential to help them relieve academic stress and build peer relationships and positive body image. For multicultural middle school students, helping them to have high self-esteem and peer attachment would be the first measure to prevent and manage depression.

Influence of Perfectionism and Coping Styles on Burnout in Clinical Nurses (임상간호사의 완벽주의 성향과 대처유형이 소진에 미치는 영향)

  • You, Ji Hye;Choi, Hyunkyung
    • Korean Journal of Occupational Health Nursing
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    • v.28 no.1
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    • pp.64-74
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    • 2019
  • Purpose: The purpose of this study was to identify the influencing factors on burnout after analyzing the relationship among clinical nurses' various perfectionism and coping styles. Methods: A descriptive, cross-sectional study was conducted with 200 clinical nurses who had six months or more years of clinical experiences from two general hospitals located in D city. The data were analyzed by t-test, one-way ANOVA, Pearson's correlation coefficients, and stepwise regression analysis using IBM SPSS statistics 23.0 program. Results: The burnout of clinical nurses was positively correlated with socially prescribed perfectionism and negatively correlated with active coping style. Socially prescribed perfectionism was positively correlated with active coping style and passive coping style. Influencing factors on the burnout of clinical nurses were socially prescribed perfectionism (${\beta}=.37$), satisfied work unit (${\beta}=-.64$) and neutral satisfaction of work unit (${\beta}=-.27$), over 40 years of age (${\beta}=-.21$), and active coping style (${\beta}=-.14$). The model consisting of these variables explained 42% of variance of burnout in clinical nurses. Conclusion: Based on the findings of this study developing intervention programs that consider influencing factors such as perfectionism and coping styles is needed to reduce the level of burnout of clinical nurses.

Influencing Factors in Preventive Behavior of Tuberculosis among Elementary School Teachers (초등교사의 결핵 예방행위와 영향요인)

  • Kang, Da-Hai-Som
    • The Korean Journal of Health Service Management
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    • v.12 no.3
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    • pp.157-168
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    • 2018
  • Objectives: The purpose of this study was to explore and describe the influencing factors in preventive behavior of tuberculosis among elementary school teachers. Methods: Participants were 151 teachers working at 3 elementary schools in Kimhae City, 3 in Changwon City and 2 in Miryang City. Data were collected with structured questionnaires from May. 8. to Jun. 1. in 2018. Data were analyzed by SPSS/WIN 21.0 program for descriptive statistics, t-test, ANOVA, Pearson's correlation coefficient and stepwise multiple regression. Results: The preventive behavior of tuberculosis among elementary school teachers were significantly positive correlated with knowledge(r=.275, p=.001), attitude(r=.493, p<.001) and self-efficacy(r=.280, p=.001). Moreover, The significant factors of the preventive behavior of tuberculosis were attitude(${\beta}=.341$, p<.001), gender(${\beta}=.407$, p<.001), smoking status(${\beta}=.210$, p=.004), self-efficacy(${\beta}=.187$, p=.005) and knowledge(${\beta}=.145$, p=.026). Conclusions: In this study, in order to promote the preventive behavior of tuberculosis among elementary school teachers, it is necessary to find ways to increase knowledge, attitude, and self-efficacy of tuberculosis, which are significant influencing factors. In addition it would be possible to develop more effective and efficient nursing intervention program if the individual characteristics of the subjects such as gender and smoking status are considered.