• Journal of Pharmaceutical Investigation
• /
• v.20 no.3
• /
• pp.153-159
• /
• 1990

To increase the solubility of fentiazac which is used widely as a non-steroidal antiinflammatory drug, its inclusion complex and suppositories were prepared and studied. Inclusion complexes of fentiazac with ${\beta}-cyclodertin$ $({\beta}-CyD)$ were prepared by four diffrent methods; coprecipitation method, kneading method, solvent evaporation method, freeze drying method. Suppositories of $fentiazac/{\beta}-CyD$ with PEG 1500 and Witepsol H-15 were prepared by solvent evaporation method and freeze drying method. Inclusion complex formation of fentiazac with ${\beta}-CyD$ was ascertained by powder X-ray diffractometry, differential scanning calorimetry and IR spectroscopy. The dissolution rate of fentiazac from the inclusion complex increased in distilled water and KP 2nd disintegration test fluids (pH 6.8) but extemly decreased in KP 1st disintegration test fluid (pH 1.2). Inclusion complexes prepared by freeze drying method and solvent evaporation method were similar. Freeze drying method seemed to be suitable for preparation of complex with most higher dissolution rate but coprecipitation method seemed not to be suitable. The dissolution rate of fentiazac increased markedly by ${\beta}-CyD$ complexation. The release rates of suppositories increased in the following order. Complex prepared by freeze dying method in PEG 1500 > complex prepared by solvent evaporation method in PEG 1500 > fentiazac in PEG 1500 > complex prepared by freeze dying method in Witepsol H-15 > complex prepared by solvent evaporation method in Witepsol H-15 > fentiazac in Witepsol H-15.

• Journal of Korean Academy of Nursing Administration
• /
• v.19 no.4
• /
• pp.513-524
• /
• 2013

Purpose: This study was conducted to identify ethical climate factors in hospitals and analyze their influence on job satisfaction and organizational commitment. Methods: A convenience sample of 196 nurses from one national university hospital in J city participated in this descriptive study survey. Instruments included the Ethical Climate Questionnaire, Job Satisfaction Scale, and Organizational Commitment Scale. Cronbach's ${\alpha}$ and factor analysis were done to test reliability and construct validity of the scales. Data were collected from March 15 to March 25, 2013 and analyzed using descriptive statistics, one-way ANOVA, t-test, Pearson correlation, and multiple regression with SPSS/WIN 18.0. Results: Seven ethical climate factors were identified; laws and professional codes, social responsibility, company rules and procedures, self-interest, personal morality, efficiency, and friendship. Factors influencing job satisfaction were friendship (${\beta}$=.25), social responsibility (${\beta}$=.20), laws and professional codes (${\beta}$=.20), and educational level (${\beta}$=.27), explaining 37.6% of variance in job satisfaction. Factors influencing organizational commitment included social responsibility (${\beta}$=.29), friendship (${\beta}$=.27), laws and professional codes (${\beta}$=.23), and age (${\beta}$=.19), with explanatory power of 44.6%. Conclusion: Results can be used as preliminary data for developing new strategies to establish positive ethical climates in hospital environments and thus enhance nurses' job satisfaction and organizational commitment.

• Journal of the Korea Convergence Society
• /
• v.10 no.11
• /
• pp.557-564
• /
• 2019

The purpose of this study was to examine the influencing factors of job engagement among Korean police officers. This was the secondary analysis of data from the 5th Korean Working Conditions Survey (KWCS). The study subjects included 185 Korean police officers. Collected data were analyzed using descriptive statistics, t-test, ANOVA, Pearson's correlation and multiple regression with IBM SPSS Statistics 24.0 program. Job insecurity (${\beta}=-.34$, p<.001), job reward (${\beta}=.39$, p<.001), subjective health status (${\beta}=.22$, p<.001), and organizational justice (${\beta}=.20$, p=.002) were significant influencing factors on job engagement, explaining 59.3% of the variance (F=34.26, p<.001). Effective and systematic strategies to improve Korean police officers' job engagement should focus on job reward, job insecurity, subjective health status, and organizational justice. The results of this study can be utilized as base data to improve Korean police officers' job engagement.

• Journal of the Korea Convergence Society
• /
• v.9 no.11
• /
• pp.529-538
• /
• 2018

The purposes of this study were to examine the stress, quality of sleep, Social support according to Myes-Briggs Type Indicator(MBTI) personality type in nursing students. Structured questionnaires were used for survey with a convenience sample of 290 nursing students. Data were analyzed using descriptive statistics, t-test, Pearson's correlation coefficient, and multiple regression with SPSS/WIN 18.0. Extroversion preference(${\beta}=.23$, p=.047) in quality of sleep, thinking prefernce((${\beta}=.06$, p=.025) in tangible support, judgement preference(${\beta}=.24$, p=.014) in appraisal support and perception preference(${\beta}=-.21$, p=.011) in Self-esteem maintenance were significantly associated factors with stress. Therefore, intervention programs for managements of stress should include systematic and indivisual intervention through the convergence of departments, university and specialists in nursing students.

• Journal of the Korea Convergence Society
• /
• v.9 no.11
• /
• pp.561-567
• /
• 2018

The study was investigate the effect of family stress and job stress on depression in middle man. A questionnaire was completed by 127 C & K city middle aged mans from july 1 to August 20 2018. The data were analyzed by SPSS/WIN 21.0 program, descriptive statistics, ANOVA, t-test, and Pearson correlation coefficient calculation and multiple regression analysis. Differences in family stress job stress depression according to general characteristics of middle-aged men showed significant difference in economic status and old age instability. The variables affecting depression are job stress(${\beta}=0.288$, p<.001), aging anxiety(${\beta}=0.142$, p<.001), economic status(${\beta}=0.035$, p<.001), family stress(${\beta}=0.016$, p<.001). As a way to reduce family stress and job stress, it is necessary to deal with health care and family conflict such as exercise hobby life relaxation.

• Journal of Home Health Care Nursing
• /
• v.26 no.2
• /
• pp.199-209
• /
• 2019

Purpose: This study was conducted to determine factors affecting the positive feelings and care burden of elderly residents' primary caregivers in long-term care facilities. Methods: The survey was conducted between November and December 2018. A structured questionnaire was used to collect data, and 148 individuals voluntarily participated. The collected data were examined through descriptive statistical analysis using SPSS WIN ver.24.0, t-test, one-way Anova $Scheff{\acute{e}}$ test, Pearson's correlation coefficient, and multiple regression. Results: Factors that significantly affected caregivers' positive feelings included caregivers' education level(${\beta}=-.32$, p<.001), social support(${\beta}=.31$, p<.001), care burden(${\beta}=-.29$, p=.001), and total support fee(not more than 1.5million won)(${\beta}=-.18$, p=.012). The explanation power was as high as 40.0%(Adj $R^2=.40$). Factors that significantly affected caregivers' burden included social support(${\beta}=-.25$, p=.002), positive feelings(${\beta}=-.25$, p=.002), elderly individual's religion(${\beta}=-.17$, p=.007), and elderly individual's marriage status(${\beta}=.17$, p=.021). The explanation power was as high as 45.0%(Adj $R^2=.45$). Conclusion: Our results suggest that it is necessary to increase social support for elderly residents' primary caregivers in long-term care facilities. This can be helpful to decrease burden and enhance positive feelings in caregivers. We should also collect caregivers' information as well to provide appropriate assistance.

• The Korean Journal of Health Service Management
• /
• v.9 no.3
• /
• pp.201-210
• /
• 2015

Objectives : The purpose of this study was to identify the effect on cognitive function in elderly people above 65 years of age. Methods : The data were collected from June 1 to August 30 2014. Data were collected by questionnaire from 994 elderly people. The instruments for this study were ADL, IADL, depression, MMSE-DS. The data were analyzed using descriptive statistics, t-test, ANOVA, Pearson's correlation coefficients, multiple linear regression with the SPSS/WIN 18.0 program. Results : The significant factors influencing MMSE-DS were education(${\beta}=-0.314$, p<.001), IADL(${\beta}=0.196$, p<.001), age(${\beta}=-0.168$, p<.001), exercise time(${\beta}=0.089$, p=.004), economic conditions(${\beta}=0.086$, p=.007), depression(${\beta}=-0.084$, p=.001), income(${\beta}=-0.083$, p=.003), sleep time(${\beta}=-0.079$, p=.001), medical insurance(${\beta}=0.059$, p=.024) and leisure(${\beta}=0.057$, p=.039). Conclusions : Based on the study, subjects with cognitive impairment detected at an early stage it is necessary to intervene in consideration of the individual characteristics and to develop and apply the program that improve the living habits such as exercise and sleep, and decreasing depression.

• The Korean Journal of Health Service Management
• /
• v.8 no.2
• /
• pp.89-100
• /
• 2014

The purpose of this study was to reveal association between medical service quality, consumer satisfaction, service value and customer loyalty. Medical service quality was composed of physical quality, personal quality, technical quality, procedural quality. We thought these factors affect to the consumer satisfaction, service value and customer loyalty. For this study, 221 dental patients in Busan and Ulsan are participated in this study. The data were analyzed with descriptive statistics, t-test, ANOVA, pearson's correlation coefficients, and stepwise multiple regression analysis with SPSS 18.0 program. In conclusion, we obtained the next results. First, the influencing factor in consumer satisfaction were physical quality(${\beta}$=.519), personal quality(${\beta}$=.262), procedural quality(${\beta}$=.110), adjusted $R^2$=.537. Second, the influencing factor in service value were physical quality(${\beta}$=.253), personal quality(${\beta}$=.251), technical quality(${\beta}$=.210), procedural quality(${\beta}$=.136), adjusted $R^2$=.401. Third, the influencing factor in customer loyalty were personal quality(${\beta}$=.343), physical quality(${\beta}$=.302), procedural quality(${\beta}$=.148), adjusted $R^2$=.398. As dental patients' desire to medical service quality becomes diversified, the analysis result is considered to help the future dental service management.

• Journal of the Korean institute of surface engineering
• /
• v.37 no.4
• /
• pp.234-241
• /
• 2004

Cavitation erosion properties of the Cu-9Al-4.5Ni-4.5Fe alloys (Al-bronze) surface-modified by flame quenching process have been investigated. After flame quenching at above $T_{\beta}$, the surfaces of Al-bronze with $\alpha$ + $\textsc{k}$ structure have been changed into the $\alpha$ + $\beta$' martensite phases by the eutectoid reaction of $\alpha$ + $\textsc{k}$\longrightarrow$\beta$ followed by the martensite transformation of $\beta$\longrightarrow$\beta$'. As a result of cavitation test, the measured incubation time and erosion rate of the $\alpha$ + $\beta$' alloy was 1.2 times higher and 1.5 times lower, respectively, compared to those of the conventional $\alpha$ + $\textsc{k}$ alloys, showing a remarkable increase of cavitation resistance with the formation of $\beta$' martensite. This is attributed to a preferential erosion of the $\textsc{k}$ precipitates that show the lowest resistance among the $\alpha$, $\textsc{k}$, $\beta$' phases under cavitation loading.ases under cavitation loading.

• Journal of Veterinary Clinics
• /
• v.5 no.1
• /
• pp.23-30
• /
• 1988

A total of 127 foremilk samples from dairy farms in Chonnam district was examined for the subclinical mastitis eve. six months, using a method of the N-acetyl-${\beta}$ -D-glucosaminidase (NAGase) test in relation to the California mastitis test(CMT) and the somatic tell count(SCC) and the compatibility and efficiency rating between the NAGase test and the other screening test were conducted. Fifteen subclinically mastitic cows were treated with a single oral dose of 7.5mg/kg of levamisole hydrochloride. The results are summarized as follows. 1. A linear relationship was found among the NAGase level, the CMT score and the SCC level, and it was found that NAGase activity measurements were comparable with other screening tests for diagnosing cows with mastitis. 2. Compatibilites between the NAGase and the CMT were 96.1%, and that of the NAGase and SCC were 93.7%. On the other hand, relative efficiency ratings of Postle's equation between the NAGase and CMT were 89.4%, and that of the NAGase and SCC were 84.1%. 3. Considering the result of CMT, SCC and NAGase level after treatment with levamisole hydrochloride it seemed to be of special value in the treatment of bovine subclinical mastitis.