• 제목/요약/키워드: behavioral test

검색결과 1,284건 처리시간 0.024초

Neural Mechanisms Underlying Antidepressant-Like Effects of Glycyrrhizae Radix in Rats

  • Park, Hyun-Jung;Shim, Hyun-Soo;Shim, In-Sop;Lee, Tae-Hee
    • 동의생리병리학회지
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    • 제24권6호
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    • pp.1053-1058
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    • 2010
  • Glycyrrhizae radix (GR) is an herbal medicine commonly used in East Asia for treating a variety of diseases, including stomach disorders. In this study, the antidepressant-like activity of GR was investigated using the forced swimming test (FST) in rats. After the FST, the expression of c-Fos and corticotrophin releasing factor (CRF) was assessed by immunochemistry of brain samples from the paraventricular nucleus of the hypothalamus (PVN). The results of the FST showed that a high dose (400 mg/kg) of extract was very effective in reducing immobility(P<0.01), and increased climbing. In addition, treatment with GR (400 mg/kg) significantly decreased the expression of c-Fos and CRF in the PVN, compared to controls. In conclusion, the findings of this study demonstrated that GR effectively reduced behavioral and physiological depression responses in an animal model of depression, suggesting that GR might be useful in the treatment of clinical depression.

여자 중$\cdot$고등학교 학생들의 의복행동에 관한 연구 -교복을 중심으로- (Attitudes toward School Uniform and Clothing Behavior among High School Girls)

  • 김영인;강혜원
    • 한국의류학회지
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    • 제5권2호
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    • pp.13-19
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    • 1981
  • The purpose of this study was to investigate the relationships among the variables of attitudes toward school uniform, three aspects of clothing behavior, self-concept, and selected behaviors. Instruments used to test the hypotheses were 12 items selected from the Behavior Test by Laubach, The Perceptual Orientation Scale by Choi, 14 items to assess the attitudes toward school uniform, and 21 modified items to evaluate conformity, fashion, and modesty in clothing. The questionnaires were completed by 484 2nd grade junior and senior high school girls in Seoul. Statistical analysis was performed using the correlation coefficient, $x^2$-tests, and t-tests. The findings could be summarized as follows: 1) Perceptual Orientation and Behavioral Orientation were not significantly related to attitudes toward school uniform. 2) Perceptual Orientation and Behavioral Orientation were negatively related to clothing conformity, 3) Attitudes toward school uniform and clothing behavior were partially different by the grade level and the type of school. 4) Fashion was positively related to conformity, but negatively related to modesty in clothing.

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한국과 연변조선족 부모별거 아동의 탄력성과 양육요인 및 사회정서적 적응력간의 관계 (The Relations mong Children's Resilience, Child Rearing Factors and Socio-Emotional Adjustment in Korean and Yanbian Korean-Chinese Shildren Separated from Parents)

  • 천희영;옥경희;황혜정
    • 가정과삶의질연구
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    • 제26권2호
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    • pp.57-70
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    • 2008
  • The focus of this study was finding out the relations among resilience of children separated from parents, child rearing factors and socio-emotional adjustment in Korean and Yanbian Korean-Chinese regions. Subjects were elementary school $5{\sim}6$ graders separated from their parents(184 in Korea and 81 in Yanbian). Data analysis was by Pearson's r, F-test and t-test. Resilience of Korean-Chinese children was higher than that of Korean children. Caregivers' child rearing behavioral factor than other child rearing factors was significant for children's resilience, and especially for Korean children, caregivers' child rearing psychological factor -efficacy and stress variables- were meaningful. Socio-emotional adjustment was significantly different between resilience high and low groups in both regions. Implications are that regional differences, caregivers' psychological and behavioral child rearing factors should be considered in supporting the development of children's resilience and socio-emotional adjustment.

내시경검사 대상자의 정보인지, 불안, 불편 및 정보의 가치 (Awareness of Information, Anxiety, Distress, and Perceived Value of Information in Patients undergoing Endoscopic Examination)

  • 손정태
    • 기본간호학회지
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    • 제10권2호
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    • pp.198-205
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    • 2003
  • Purpose: A descriptive study was conducted to identify awareness of information, emotional distress, behavioral distress, and perceived value of information in clients who were scheduled for endoscopic examinations, and to determine correlations between the variables. Method: Participants were 87 clients who were scheduled for endoscopic examinations; gastroscopy, bronchoscopy, and colonoscopy. The questionnaires were collected from September to December, 2002 by a trained nurse. Self reports, interviews, and observations were used. Data were analyzed with frequencies, percentages, means, Pearson correlation coefficients, ANOVA, and Scheffe post test using the SPSS/PC 9.0. Result: The score for awareness of information was 17.46, state anxiety was 47.26, emotional distress during exam was 2.90, behavioral distress was 11.18, and perceived value of information was 4.21, Clients aged above 60 showed significantly lower awareness of information than other groups. Clients undergoing broncoscopy reported significantly higher emotional distress during the ekam than subjects for colonoscopy. Clients undergoing gastroscopy showed significantly higher behavioral distress than any of the others. There were no relationships between awareness of information and anxiety, but, a significant positive relationship was found between anxiety and emotional distress during exam, between emotional distress and behavioral distress, and between awareness of information and perceived value of information. Conclusion: Awareness of information by the clients through provision of an educational booklet was low, and clients showed moderate level of state anxiety. Research studies are needed to compare providing information with other interventions for comfortable progress of endoscopic examinations. Especially specific strategies should be established for elderly clients to facilitate awareness of information.

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서울 남자 직장인의 건강행위실천별 건강식품 섭취 행동 의도 및 영향 요인 (Health Food Intake and Behavioral Intentions to Take Health Food on Male Workers by Practiced Health Behavior in Seoul)

  • 이승교
    • 한국지역사회생활과학회지
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    • 제21권2호
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    • pp.243-257
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    • 2010
  • This study was conducted to search the health food intake behavioral intentions of male workers. The health-related behavior of 150 subjects were compared(smoke, alcohol drink, breakfast, BMI, sleep, exercise and health check). On the basis of the Theory of Planned Behavior, the factors health-food intake behavior were evaluated; there were normative beliefs, motivation for compliance, subjective norms, social influence factors, and barriers as perceived behavior control. The results were showed with five points by the Likert scale and Significance by t-test. The most frequently consumed health food was tea(3.40/4points) followed by healthy drinks(2.49/4). As behavioral beliefs, if consumption of 'nutritional supplements'(3.61/5) and 'fatigue recovery'(3.62/5) received the highest scores. As a result, the idea of 'nutritional supplements'(3.94/5) and 'fatigue recovery'(4.06/5) were the important aspects, but others were also positively evaluated. As a sub-factor of subjective norms on normative beliefs, The highest social groups to encourage consumption of health food were parents (3.93/5), and the lowest were doctors (3.02/5). The most influential people were doctors (3.67/5) and spouses (3.65/5). Barriers to consumption health food were side effects (1.09/5) and price (2.08/5). Taking Ginseng products and other processed foods (juice, honey, bamboo, etc.) were correlated with health concern (p<0.05). Taking traditional stamina foods was correlated with dietary habit recognition (p<0.05). Mineral intake was positively correlated with age. Healthy drinks was negative (p<0.05). Minerals and supplement consumption were correlated with the practice of healthy behavior (p<0.01).

Effects of Glycyrrhizae Radix on Repeated Restraint Stress-induced Neurochemical and Behavioral Responses

  • Park, Hyun-Jung;Shim, Hyun-Soo;Kim, Hyun-Young;Kim, Kyung-Soo;Lee, Hye-Jung;Hahm, Dae-Hyun;Shim, In-Sop
    • The Korean Journal of Physiology and Pharmacology
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    • 제14권6호
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    • pp.371-376
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    • 2010
  • Glycyrrhizae radix (GR) is an herbal medicine that is commonly used in the East Asia for treating a variety of diseases, including stomach disorders. The objective of the present study was to examine the anti-stress effects of GR on repeated stress-induced alterations of anxiety, learning and memory in rats. Restraint stress was administered for 14 days (2 h/day) to the rats in the Control and GR groups (400 mg/kg/day, PO). Starting on the eighth day, the rats were tested for spatial memory on the Morris water maze test (MW) and for anxiety on the elevated plus maze (EPM). We studied the changes of the expressions of cholineacetyl transferase (ChAT) and tyrosine hydroxylase (TH) in the locus coerleus (LC) using immunohistochemistry. The results showed that the rats treated with GR had significantly reduced stress-induced deficits on their learning and memory on the spatial memory tasks. In addition, the ChAT immunoreactivities were increased. Gor the EPM, treatment with GR increased the time spent in the open arms (p<0.001) as compared to that of the control group. Moreover, GR treatment also normalized the increases of the TH expression in the LC (p<0.001). In conclusion, administration of GR improved spatial learning and memory and reduced stress-induced anxiety. Thus, the present results suggest that GR has the potential to attenuate the behavioral and neurochemical impairments caused by stress.

행동경제학 관점에서 프라이버시 역설에 관한 연구 (A Study on Privacy Paradox from the Behavioral Economics Perspective)

  • 김종기;김상희
    • 정보화정책
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    • 제22권3호
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    • pp.16-35
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    • 2015
  • 최근 프라이버시 분야에서는 태도와 행동의 일관성 가정을 토대로 진행되어온 기존의 프라이버시 연구를 부정하고, 프라이버시 태도가 더 이상 행동에 영향을 미치지 않는다고 주장하는 프라이버시 역설 관점의 연구가 점점 증가하고 있는 추세이다. 본 연구에서는 정보제공의도와 정보제공행동 간의 관계에서 프라이버시 역설 현상이 실제로 존재하는지 확인하고, 왜 이러한 현상이 나타나는지 행동경제학에서 논의되는 이중 프로세스 이론을 통해 설명하고자 하였다. 실증분석 결과, 정보제공의도와 정보제공행동 간에는 통계적으로 유의한 차이가 있는 것으로 나타나 프라이버시 역설의 존재가 확인되었다. 다음으로, 프라이버시 위험은 합리적 사고에 의해 지배되는 프라이버시 의사결정의 결과인 정보제공의도에, 프라이버시 신뢰는 직관적 사고에 의해 지배되는 실제 교환관계의 결과인 정보제공행동에 영향을 미치는 것으로 분석되어 이들이 상황에 따라 차별적 역할을 한다는 것이 확인되었다.

Neuronal Apoptosis: Pathological Basis of Behavioral Dysfunctions Induced by Angiostrongylus cantonensis in Rodents Model

  • Luo, Shiqi;OuYang, Lisi;Wei, Jie;Wu, Feng;Wu, Zhongdao;Lei, Wanlong;Yuan, Dongjuan
    • Parasites, Hosts and Diseases
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    • 제55권3호
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    • pp.267-285
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    • 2017
  • Angiostrongylus cantonensis invades the central nervous system (CNS) of humans to induce eosinophilic meningitis and meningoencephalitis and leads to persistent headache, cognitive dysfunction, and ataxic gait. Infected mice (nonpermissive host), admittedly, suffer more serious pathological injuries than rats (permissive host). However, the pathological basis of these manifestations is incompletely elucidated. In this study, the behavioral test, histological and immunohistochemical techniques, and analysis of apoptotic gene expression, especially caspase-3, were conducted. The movement and motor coordination were investigated at week 2 post infection (PI) and week 3 PI in mice and rats, respectively. The cognitive impairs could be found in mice at week 2 PI but not in rats. The plaque-like lesion, perivascular cuffing of inflammatory cells, and dilated vessels within the cerebral cortex and hippocampus were more serious in mice than in rats at week 3 PI. Transcriptomic analysis showed activated extrinsic apoptotic pathway through increased expression of TNFR1 and caspase-8 in mice CNS. Immunohistochemical and double-labeling for NeuN and caspase-3 indicated the dramatically increased expression of caspase-3 in neuron of the cerebral cortex and hippocampus in mice but not in rats. Furthermore, western-blotting results showed high expression of cleaved caspase-3 proteins in mice but relatively low expression in rats. Thus, extrinsic apoptotic pathway participated in neuronal apoptosis might be the pathological basis of distinct behavioral dysfunctions in rodents with A. cantonensis infection. It provides the evidences of a primary molecular mechanism for the behavioral dysfunction and paves the ways to clinical diagnosis and therapy for A. cantonensis infection.

Effect of Education on Knowledge, Attitude and Behavioral Intention in Family Relative with Colorectal Cancer Patients Based on Theory of Planned Behavior

  • Baghianimoghadam, Mohammad Hosein;Ardakani, Mojtaba Fattahi;Akhoundi, Mohsen;Mortazavizadeh, Mohammad Reza;Fallahzadeh, Mohammad Hosein;Baghianimoghadam, Behnam
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권12호
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    • pp.5995-5998
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    • 2012
  • Background: Colorectal cancer is one of most common cancers in women and men and one of the major causes of death due to neoplasia. Colonoscopy is considered as the most accurate diagnostic procedure to detect colorectal cancer at the earlier stages. Objectives: The current study aimed to evaluate the effects of an education program using the Theory of Planned Behavior on promoting behavioral intention among first degree relatives of colorectal cancer patients. Materials and Methods: A quasi-experimental study conducted to evaluate the effectiveness of an educational program to promote attitudinal factors associated with early detection of colorectal cancer in 99 first degree relatives of colorectal cancer patients aged more than 20 years in Yazd city, Iran. A researcher made questionnaire forwhich validity and reliability were confirmed by expert point of view and pilot testing was employed for data collection. Questionnaires were filled in before and after educational intervention. The registered data were transferred to SPSS 19 and analyzed by paired T-test, Man-Whitney and Wilcaxon. Results: Mean scores of knowledge, attitude, perceived behavioral control and intention regarding colorectal cancer increased after education significantly (P<0.05). Conclusions: Application of the Theory of Planned Behavior has positive influence on promoting intention behavior. It is therefore recommended to apply educational programs to promote behavioral intention.

환경 문제에 대한 평가 도구 개발 및 국민학생과 중학생의 태도 조사 연구 (A study on elementary school students' and middle school students' attitudes toward environmental problems)

  • 우현경;정영란
    • 한국과학교육학회지
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    • 제14권2호
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    • pp.225-235
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    • 1994
  • Concidering environmental education as an ultimate resolution for environmental problems, we conducted a study focusing on affective matters. An instrument was developed to evaluate attitudes of elementary and middle school students toward environmental problems. To develop a reliable Likert-type evaluation instrument scale with which emotional intensity could be judged, mean, standard deviation, response frequency distribution, discrimination index, reliability were calculated. As a result, 21 statements for recognition level and 14 statements for behavioral level were made(The Cronbach alpha coefficient of the instrument was .786). This instrument was used to evaluate 5th and 6th grade elementary school students and 1st and 2nd grade middle school students(total number of subjects was 980). The result of this survey can be summarized as follows. 1. Students recognized the seriousness of environmental problems but they did not behave in such a manner as to prevent it. 2. As a result of t-test, behavioral level score of elemenatary school students was significantly higher than that of middle school students(p<.001). 3. This study showed that there was a significant correlation between the recognition level score and the behavioral level score(r=.386, p<.001). 4. Two-Way ANOVA was used to analyze that there was any significant difference according to grade and sex. The results were as follows. (1) No significant difference was found in total score. (2) On recognition level, female students' score was signigicantly higher than that of male students(p<.01). (3) On behavioral level, higher-grade students' score was lower than that of lower-grade-students (p<.001).

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