• 한방재활의학과학회지
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• 제34권3호
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• pp.89-96
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• 2024

Objectives This study is designed to evaluated the safety of peony root extract tablet in healthy male volunteers. Methods 12 healthy male volunteers were recruited, and this study was conducted by a single center. The safety was evaluated by collecting laboratory test and vital signs of volunteers. As the registration process, 12 subjects were assigned by serial number. To evaluate safety, vital signs were checked and blood samples were collected 4 times during the screening period, pre & post-administration (after 8 hours) and post-administration (after 7 days). The difference in variables was summarized by the mean±standard deviation. The normality test was carried out using the Shapiro-Wilk test and Kolmogorov-Smirnov test. When normality is fulfilled, a paired t-test is applied and the significance level was p<0.05. And the incidence of all adverse effects and serious adverse effects are shown in percentage. Results In the case of vital sign, body temperature (BT) (℃) was 0.06±0.05 ℃ (p=0.008), and there was a statistically significant difference in before and after administration. However, clinical symptoms were not occurred and BT (℃) of all subjects before and after administration showed values within the normal reference value. There was no significant difference from the control group in all other vital signs and laboratory test data. And no side-effects associated to clinical trial drugs were followed. Conclusions The peony root extract tablet was considered to be safe for healthy male volunteers.

• 대한한방부인과학회지
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• 제35권1호
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• pp.1-11
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• 2022

Objectives: Management of the postpartum period is important for the health of mothers, and postpartum edema is one of the management targets. In this study, the relationship between the value measured by the device and the postpartum edema sensation was examined to explain the subjective sensation of the mother as an objective value. Methods: Data from 54 cases provided by 24 mothers within 6 weeks postpartum were used in the study. The degree of postpartum edema sensation was measured using a visual analog scale (VAS), and the effect of VAS changes on the body edema index and weight change before and after childbirth was estimated through linear regression analysis. Results: As a result of the regression analysis, when the edema sensation of the mothers VAS increased by 1 point, the Inbody edema index increased by 0.002 points (p=0.000, R²=0.272), and when the VAS increased by 1 point, the weight gain increased by 0.99 kg compared to before pregnancy (p=0.000, R²=0.243), and when VAS increased by 1 point, weight loss decreased by 0.56 kg compared to just before childbirth (p=0.004, R²=0.136). Conclusions: The results of this study, in which the edema sensation of postpartum mothers was statistically significantly related to the edema index and weight change before and after childbirth, showed that the edema sensation complained by the mother could be used as an evaluation index for postpartum edema management in the future.

• Korean Chemical Engineering Research
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• 제47권6호
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• pp.688-694
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• 2009

PCB의 먼지 제거용 세정제로 사용되는 스프레이형 세정제를 선정하여 이에 대한 청정도를 평가하였다. 친환경적인 대체 세정제를 채택하기 위해서는 세정제의 세정성, 환경성, 경제성을 평가하여 체계적인 선정절차에 의거하여 도입 및 적용하여야 한다. 객관적이고 효율적인 세정성 평가방법의 정립이 현시점에서 매우 중요하다. 본 연구에서는 여러 세정성 평가 방법들 중 표면관찰평가법인 SEM-EDX(Scanning Electron Microscopy/Energy-Dispersive X-ray) 분석과 적외선열화상카메라(THERMOVISION A20 model)를 이용하여 청정도를 평가하였다. CT-2770 모델의 사운드카드를 $2{\times}2cm$로 잘라내어 스프레이 세정 전과 후의 청정도를 SEM의 이미지 분석을 통해 관찰할 수 있었고 EDX의 성분분석을 통해 먼지의 제거율을 정량화할 수 있었다. 컴퓨터의 P4T-E 모델의 마더보드와 IPC-A-36 모델의 기판을 사용, 오염물로 먼지와 철가루를 사용하여 열화상카메라로 세정 전, 후의 상온과 $50^{\circ}C$ Oven에 방치된 시간의 차이에 따른 온도의 변화를 비교하였다.

• Journal of Korean Neurosurgical Society
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• 제54권4호
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• pp.280-288
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• 2013

Objective : Perfusion computed tomography (PCT) has the ability to measure quantitative value and produce maps of mean transit time (MTT), cerebral blood flow (CBF), and cerebral blood volume (CBV). We assessed cerebral hemodynamics by using these parameters and acetazolamide (ACZ) challenge for pre- and post-procedural evaluation in patients with unilateral cerebrovascular stenotic disease. Methods : Thirty patients underwent pre-procedural PCT with ACZ challenge, and 24 patients (80%) was conducted follow up PCT after angioplasty with same protocol. The mean MTT, CBF, and CBV were measured and compared in both middle cerebral arterial (MCA) territories before and after ACZ challenge. Hemispheric ratio and percent change after ACZ challenge were calculated before and after angioplasty. Results : The mean stenosis rate was 76.6%. Significant increases in MTT (32.6%, p=0.000) and significant decreases in CBF (-14.2%, p=0.000) were found in stenotic side MCA territories. After ACZ challenge, there were significant changes in MTT (37.4%, p=0.000), CBF (-13.1%, p=0.000), and CBV (-10.5%, p=0.001) in pre-procedural perfusion study. However, no significant increases were found in MTT, or decreases in CBF and CBV in post-procedural study. There were no significant changes after ACZ challenge also. In addition, the degrees of these changes (before and after ACZ challenge) were highly correlated with the stenotic degrees in pre-procedural perfusion study. Conclusion : PCT with ACZ challenge appears to be a useful tool to assess the cerebral perfusion status especially in patients with unilateral symptomatic stenotic disease.

• 인간식물환경학회지
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• 제22권5호
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• pp.445-454
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• 2019

This study was conducted to find out physical changes in the blood pressure and saliva cortisol of patients with high blood pressure and diabetes after participating in agro-healing activities. The saliva cortisol and blood pressure of 14 males and females aged 49.79±10.48 on average were measured after participating in agro-healing activities. The saliva collection system was used, and their satisfaction level for the program was also surveyed. Changes in the values before and after participating in the agro-healing activities were compared and analyzed. The cortisol concentration, a stress hormone, was reduced from 6.76nmol/L before the program to 4.86nmol/L after the program, down by 1.9nmol/L, which was a statistically significant difference (z=-3.170, p<.01). In addition, the cortisol concentration was gradually reduced through the entire program from Session 1 to Session 7. Changes in the blood pressure of subjects before and after participating in agro-healing activities were examined, and the total systolic and diastolic blood pressure continuously decreased after participating in agro-healing activities through the entire program from Session 1 to Session 7. Their systolic blood pressure was reduced statistically significantly (z=-1.947, p<.05). Also, participants' satisfaction was analyzed and it was found that more than 95% of participants answered 'satisfied' and 'very satisfied' with agro-healing activities. Therefore, these results indicate that agro-healing activities performed in the healing-farm had a positive impact on the cortisol concentration and blood pressure of patients with chronic diseases such as diabetes and high blood pressure. In addition, their high satisfaction for this program seemed to improve the psychological and physiological conditions of subjects.

• 수산해양교육연구
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• 제27권5호
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• pp.1236-1251
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• 2015

This study examined understanding and attitude of sustainable development(SD) of 38 college students in a nuclear power plant construction after education for sustainable development(ESD) through panel discussion. The results were as follows: First, after lesson 66% of students were expected that SD is possible if scientific technology is developed and a frugal life for the protection of environment is carried out. However, the remaining students regarded SD as an ideal concept, because they thought it is not possible to pursue environmental sustainability and socio-economic development simultaneously. Second, students' opinions in the evaluation of constructing a nuclear power plant in three aspects(environment, society and economy) before and after panel discussion were changed as follows; 1) After panel discussion, the objectors increased to 21% in economic evaluation, while the supporters increased to 11% in environmental evaluation. 2) Students majoring in engineering or natural sciences changed their opinions to agree in environmental evaluation because they considered a nuclear power plant safe and eco-energy. However students majoring in social science/business or liberal arts/arts changed their opinions to disagree in economic evaluation because they considered a nuclear power plant as high-cost energy when assessing danger-accidents cost, public consensus cost, operation and maintenance cost, and waste disposal cost. 3) This change of decision-making in students majoring in social science/business or liberal arts/arts after panel discussion was statistically significant(p<0.05). Implications of panel discussion as a teaching and learning method in ESD are also discussed.

• The Journal of Advanced Prosthodontics
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• 제1권1호
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• pp.26-30
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• 2009

STATEMENT OF PROBLEM. Qualitative and semi-quantitative methods have been developed for TMJ sound classification, but the criteria presented are completely inhomogeneous. Thus, to develop more objective criteria for defining TMJ sounds, electroacoustical systems have been developed. We used Joint vibration analysis in the BioPAK system(Bioresearch Inc., Milwaukee, USA) as the electrovibratography. PURPOSE. The aim of this study was to examine the TMJ sounds with repect to frequency spectra patterns and the integral > 300 Hz /< 300 Hz ratios via six-months follow-up. MATERIAL AND METHODS. This study was done before and after the six-months recordings with 20 dental school students showed anterior disk displacement with reduction. Joint vibrations were analyzed using a mathematical technique known as the Fast Fourier Transform. RESULTS. In this study Group I and Group II showed varied integral > 300 /< 300 ratios before and after the six-months recordings. Also, by the comparative study between the integral > 300 /< 300 ratios and the frequency spectrums, it was conceivable that the frequency spectrums showed similar patterns at the same location that the joint sound occurred before and after the six-months recordings. while the frequency spectrums showed varied patterns at the different locations that the joint sound occurred before and after six-month recordings, it would possibly be due to the differences in the degree of internal derangement and/or in the shape of the disc. CONCLUSIONS. It is suggested that clinicians consider the integral > 300 /< 300 ratios as well as the frequency spectrums to decide the starting-point of the treatment for TMJ sounds.

• 한국건축시공학회지
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• 제21권4호
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• pp.257-268
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• 2021

본 연구는 최근 급증하고 있는 공동주택의 하자분쟁과 관련하여 하자소송이 급증한 시점인 2013년을 기준으로 2013년 이전과 이후의 하자소송 판례 24건의 공종별 주요 쟁점사항에 대하여 분석한 결과 세대당 하자적출금액은 2013년 이후는 2013년 이전과 비교하여 약 5% 감소한 세대당 2,572천원이나, 세대당 판결금액은 오히려 약 19%가 증가하여 2013년 이후에는 세대당 1,916천원으로 나타났다. 공종별로 살펴보면 균열에 대한 하자가 2013년 이전과 이후 가장 큰 비율을 차지하였고, 2013년 이전에는 설비, 타일, 창호 순으로 나타났고, 2013년 이후에는 조경, 타일, 단열 및 창호공사 순으로 나타났다. 이러한 하자분쟁 예방을 위해서는 설계단계, 시공단계 및 유지보수단계에서 하자분쟁 방지 노력이 필요할 것이다.

• 한국산업보건학회지
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• 제34권1호
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• pp.35-47
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• 2024

Objectives: Many cases of lung cancer have been reported by school kitchen workers as occupational cancer. Twenty-eight schools in Gyeongsangnam-do Province were selected to evaluate the effect of improved kitchen ventilation systems. Ventilation characteristics before and after renovation were compared and design techniques were identified. Methods: In the design stage for kitchen ventilation systems, expert intervention was used to improve the designs. Ventilation characteristics and air quality were evaluated before and after the renovations. Hood face velocity and fan flow rate were measured and the smoke visualization technique was used to evaluate the capability of protecting worker's breathing zone. The concentrations of PM_0.3 were measured at points not adjacent to cooking equipment because these concentrations fluctuate greatly. Results: Mean hood face velocity increased from 0.29 m/s before renovation to 0.7m/s after renovation. The concentrations of PM_0.3 showed a roughly 95% reduction. Concentrations of CO showed more than a 75% reduction. Smoke visualization showed greater protection of workers' breathing zone. Conclusions: Advanced design techniques for school kitchen ventilation systems were applied to renovate old kitchen ventilation systems. The performance of the new kitchen ventilation systems was nearly excellent. Further improvement of design techniques is still needed, however.

• 대한치과교정학회지
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• 제54권4호
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• pp.247-256
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• 2024

Objective: This retrospective study evaluated the mandibular condyle position before and after bimaxillary orthognathic surgery performed with the mandibular condyle positioned manually in patients with mandibular prognathism using cone-beam computed tomography. Methods: Overall, 88 mandibular condyles from 44 adult patients (20 female and 24 male) diagnosed with mandibular prognathism due to skeletal Class III malocclusion who underwent bilateral sagittal split ramus osteotomy (BSSRO) and Le Fort I performed using the manual condyle positioning method were included. Cone-beam computed tomography images obtained 1-2 weeks before (T0) and approximately 6 months after (T1) surgery were analyzed in three planes using 3D Slicer software. Statistical significance was set at P < 0.05 level. Results: Significant inward rotation of the left mandibular condyle and significant outward rotation of the right mandibular condyle were observed in the axial and coronal planes (P < 0.05). The positions of the right and left condyles in the sagittal plane and the distance between the most medial points of the condyles in the coronal plane did not differ significantly (P > 0.05). Conclusions: While the change in the sagittal plane can be maintained as before surgery with manual positioning during the BSSRO procedure, significant inward and outward rotation was observed in the axial and coronal planes, respectively, even in the absence of concomitant temporomandibular joint disorder before or after the operation. Further long-term studies are needed to correlate these findings with possible clinical consequences.